Diseases are one of the most serious challenges in both developing and developed countries. According to the International Diabetes Federation, there are 285 million ill people worldwide. This total is expected to rise to 380 million within 20 years. Due to its importance, a design of classifier for the detection of symptoms of disease with optimal cost and better performance is the need of the age. The Pima Indian database at the UCI machine learning laboratory has become a standard for testing data mining algorithms to see their prediction accuracy in data classification. The proposed method uses Support Vector Machine (SVM), a machine learning method as the classifier for diagnosis of disease. The machine learning method focus on classifying disease from high dimensional medical data set. The experimental results obtained show that support vector machine can be successfully used for diagnosing disease.