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Amgen is dedicated to the fght against heart disease and has now launched Breakaway from Heart Disease™. The collective goal of this national campaign is to help make America’s heart health a priority.

Leading
Experts have been pessimistic about the future of healthcare for a while, speculating on what
it might entail in the years to come. The pandemic has altered the environment and perhaps the course of healthcare in the future. The healthcare ecosystem has been thrust into an uncharted realm of virtual doctor visits, remote working, and a supply chain plagued by severe shortages.
However, by using solutions like IoT, augmented reality, machine intelligence, and additive manufacturing, health-tech companies have the opportunity to drive efficiency and face problems. The healthcare industry has been extremely busy in recent years, yet despite the ongoing demands and needs, these companies continue to work hard and deliver regularly. The healthcare industry is similarly ready for any eventuality, despite carrying the dual burden of providing excellent patient care while under stress.
However, this abrupt change has generated several queries, starting with, will the new reality give customers the chance to get fair and high-quality treatment when they need it so they can concentrate on their long-term well-being? What will the future of healthcare look like?
Our team at Business APAC has launched a new magazine issue titled “Business APAC Leading Healthcare Companies of 2022” to learn in-depth about the future of the healthcare sector. The importance of the changes the healthcare industry will experience has been addressed in this issue by the top healthcare businesses. These businesses are certain that the healthcare industry will rebound from the COVID-19 pandemic even stronger.
Featured on the magazine cover, Origin Integrated Studios began its journey with a desire to make a difference by providing superior healthcare solutions with a team of talented, motivated, and passionate software engineers and designers. Further, in the magazine, we have highlighted several companies that are steadfastly working to deliver the best patient care and improve clinician communication. We hope to keep you rest assured as these companies are confident about a bright future.
Have a Happy and Healthy Read!


sarang mahajan Project Editor



Publisher : Archana Ghule
Editor-in-Chief : Vikram Suryawanshi
Managing Editor : Utkarsh Deshpande
Project Editors :
Prajakta Zurale Sarang Mahajan
Creative Head :
Poonam Mahajan
Graphic Designer : Aboli Purkar
Head of Distribution & Production: Aakash Mahajan
Web Development & Maintenance : Vishal More
Project Manager : Pratik Kumar
Business Analysts : Maria Smith
Advertising : Jacob Eddy


Kenneth Kee CEO



The Main Ingredient of Successful Project Implementations and Longevity

Kenneth Kee CEO
Over the years, Malaysia Healthcare has presented a seamless end-to-end healthcare journey experience, affording quality care for the peace of mind of healthcare travelers. Besides being one of the leading countries in Southeast Asia for medical tourism, the increasing aging population in Malaysia is sighted to bring revenue-earning opportunities for healthcare companies. Excelling in the Malaysian private healthcare is Origin Integrated Studios , developing innovative and creative software solutions for Malaysia and its regions. Origin is one of the very few software development companies which focuses on enterprise systems for the healthcare industry.
Origin was established in 2015 with an aim to become a household brand in the healthcare industry and focusing on a long term and trusting relationship with its customers. Headquartered in Kuala Lumpur, it is the fastest-growing Multimedia Super Corridor (MSC) status software development and solutions company. Within a year of establishment, it managed to expand in the Asian countries primarily in Indonesia and now working together with customers in their business expansion into the Philippines, Vietnam and South Korea. Origin is currently serving more than 20 hospitals and 15 clinics in Malaysia and Indonesia.
The Leader behind the Curtain
Origin was requested to deliver a state-of-art comprehensive EMR solution by a local healthcare provider. Thus, due to Kenneth Kee's (CEO) decade of experience in enterprise business software applications and solutions, the company set out to create groundbreaking products along with a team of expert software developers. Kenneth is always updated with the daily news and tech trends in the healthcare industry. As a leader, it becomes his responsibility to stay updated with the trends so that the solutions Origin provides stays relevant to the time.
Apart from this, he also attends conferences and seminars to stay connected with industry veterans, healthcare specialists, and healthcare solution vendors.
Kenneth initially started his career as a Sales Executive serving an ICT consulting company in Asia. For 18 years, he contributed

“To ensure the quality of our support services, our support team provides an immediate response to a user on any issues and provide bug fixes as and when reported 24/7.”

ales in banking, s manufacturing and healthcare industries. While he was a Vice President of Sales for the enterprises' software solutions, he decided to leave and remained as a Director till early 2020. It was then he noticed that there was a gap in the healthcare system particularly outdated client-server based hospital information system lacking in the EMR and integration to systems. This led him to venture into developing modern web-based
healthcare application software solutions with his team of passionate and talented software developers in mid-2015. “ All started from one hospital looking for hospital information system with EMR, ” said Kenneth.
Origin haspioneered in its EMR services and gaining popularity across the sector despite the
competitors in the market. Origin Electronic Medical Record (Origin EMR) is the flagship product of Origin, followed by the Origin Hospital Information System (Origin HIS) .
These two products have been developed with over 10 years of industry experience which touts high adoption rates amongst the doctors and nurses. Both of these products have gained popularity due to its accuracy and efficiency.
secure as they have been put on a stringent test by the hospital quality management team to be certified by an external auditor for hospital process flow. All security access rights and changes in the system are traceable through audit log and versioning capability.
The characteristics that distinguish Origin products are that it is developed on Java Platform i.e.
JAVA EE, the standard communitydriven enterprise software. The user interface is also developed using the latest web technologies, thus making it as intuitive, user friendly and up to date at the same time. Further, Kenneth adds, “ Origin EMR comes with iNTERFACEWARE
IGUANA HL7 interface engine which is used by more than 800+ healthcare providers and vendors. It is fully web-based support for Mozilla Firefox and Google Chrome. ”
emerge stronger than before after the COVID-19 outbreak has resolved. The same however cannot stand true for the other sectors which have been devastated. Across all sectors, the largest disruptor to productivity and the financial implications had caused the offices and business to hold and staff has been quarantined at home. Being positive, Kenneth predicts that it may take up to 6 to 9 months for a full recovery.
Kenneth concluded by saying, “ I foresee that more investors will

adopting the modernized platforms such as EMR for storing medical records digitally. Being one of the leading EMR providers Origin is experiencing a high demand from the existing hospitals for solutions that can provide digitalization or replacing the traditional healthcare systems. Also, few new hospitals are seeking the latest solutions to meet the market expectation.
“Origin addressed the issue of limitation of space capacity for the fast-growing healthcare sector, by using Origin EMR which helps efficiency in the process flow by eliminating physical medical records.”
With the pandemic adversely affecting all the businesses, Kenneth has an optimistic outlook and is hoping for the best to come from this situation. The outbreak has given notable exposure to the healthcare sector. The healthcare sector, however, is trying to manage its hold and may even
divert their investment into healthcare and related industries within this period while waiting for others such as tourism, hospitality, and entertainment. This is indeed good news for the healthcare solutions vendor. ”
With a spike in digitization and novel tech, most of the health systems in APAC have begun
In order to be upgraded and fit for all the customer requirements, the company is looking to improve the services. Thus, Origin is determined to focus on its plan for the immediate and future needs of its customers in the area of a mobile patient portal, remote patient monitoring system, integration to various vital sign monitoring devices, business analytics management dashboard and predictive analysis for the patient bill.
Our Global Vision & Mission
VISION: We are a people company that inspires young talent software developers and designers to make a positive difference in developing innovative and creative healthcare application software solutions of internationally recognized.
MISSION: To make an impact by becoming a household brand in the healthcare industry and focusing on
The OIS software provides interoperability, efficient clinical services, and better patient safety,
Ÿ With CPOE
Ø Physician orders are automatically routed to ancillary services departments for more efficient services.
Ø Improve patient safety by reducing potential human errors due to manual transcription of doctor orders.
Ÿ With EMR
Ø Real-time entry and fast access to electronic medical records.
Ø Improve patient safety through better documentation of care give.
Ø Provide system generated reports required by insurance or discharges.
Ø Accessing patient information with mobile devices.
Ÿ With Nursing Module
Ø Online nursing documentation for a care plan, order fulfillment, eMAR, etc.
Ø Online clinical handover during the shift for better and safer care.
Ø Accessing patient information with mobile devices.
Ÿ With Document Scanning Management module
Ø Digitizing and online filing of paper-based clinical documentation.
Ø Seamless integration with EMR to achieve complete online patient records.
Ÿ With Reporting module
Ø Provide accurate reporting mechanisms to assist management decision and promote accountability.
Ø Leveraging on the integrated platform for ease of data collection.
Ø Using Business Intelligence system or tools. Automate accurate reporting.










Ashwini Kumar CEO

Over the last two decades, the healthcare industry has seen a major consolidation of existing companies and the emergence of startups. Many companies are moving from a traditional business approach to newer business verticals like medical devices, valueadded wellness products, global licensing, and geographical expansion.
All these areas require major compliance in terms of regulatory & commercialization support. The major challenge is to coach these companies regarding the newer policies and key information which is essential for their business continuum & expansion. Based in India, CliniExperts is the country’s leading regulatory solutions that assist companies to handle such challenges. It offers structured and responsive regulatory services, complying with the highest quality standards. Essentially, it’s the only Indian organization to offer end-to-end regulatory and affiliated business solutions to the life sciences industry.
CliniExperts offers end-to-end business solutions which include identification of product opportunity, its regulatory approval, and setting up the sales channels for commercialization. Its structured and responsive services comply with the highest quality standards which cater to a vast range of products. Thus, CliniExperts helps clients to ease through various regulatory aspects and acts as a bridge that joins research with the market, bringing quality
healthcare products and services to the healthcare sector.
Furthermore, CliniExperts provides value-added services like business intelligence, product portfolio building, distribution set-up, and marketing and logistics solutions that help clients achieve commercial success. Since its inception in 2009, CliniExperts has facilitated unified and market-ready outcomes which offer benchmark services for the pharmaceutical, biological and vaccine, medical device, diagnostic kit, food, nutraceutical, cosmetic, and pesticide and insecticide industries.
Since its establishment, CliniExperts’team has maintained a “quality first” culture in the company’s environment. Therefore, to achieve the best quality in its services, the company followed a process-driven structured workflow. Our India and Singapore offices support our clients, as a result, with our “gamut of quality services”, many global firms entered the Indian and Southeast Asian markets. To date, CliniExperts has helped over 35 offshore companies to establish their businesses in these regions. It has also secured over 5,000 approvals for its 450+ clients worldwide from various developing and developed countries like the USA, Canada, UK, Germany, Spain, Japan, Ireland, etc. Today, CliniExperts is aiming to build new partnerships across the geographies to build a Globally acclaimed organization.
In addition to the quality-centric approach, the management
board of CliniExperts believes in the philosophy of“giving back” to society. The leading healthcare service provider connects with activities that will contribute to improving healthcare facilities for underprivileged. The best thing to mention is that CliniExperts donates medical devices, medicines, and other essential consumables to charities engaged in rural development. The team of CliniExperts also participates in healthcare programs conducted for children suffering from rare diseases.
Ashwini Kumar, the CEO of CliniExperts is focused on offering efficient and quality-driven regulatory affairs services to his clients. Committed to the need for absolute perfection and ethical correctness, Ashwini knows that the current reputation and excellent services of CliniExperts are the result of the dedicated work from his highly motivated, talented, and experienced team of professionals. He proudly says, “The team members of CliniExperts have brought us to the current heights in the life science industry as a leading regulatory solutions provider and licensing organization.”
The team of CliniExperts is made of professionals from various related backgrounds including Doctorates, Pharmacy, Food / Nutritional experts, and Medical engineers covering the entire spectrum of Healthcare products. Additionally, to help team members stay updated with the latest regulatory reforms, an expert professional for every team regularly watches for updates on regulatory changes. Today, with the dedicated team of experts, CliniExperts is recognized for its meritocracy, stringent QA and QC standards, up-to-the-minute knowledge base, professionalism, and unquestionable ethics.
The COO of CliniExperts, Ms. Rashmi Verma, believes that they have many miles to go and the team at CliniExperts is striving hard towards their goal of expanding the company
across the world. To keep the team capabilities updated with the evolving business environment, CliniExperts provides regular training and coaching. The company also offers structured programs, peer-to-peer learning and mentor-mentee coaching for employees.
These programs assist the employees to stay updated with the latest advancements in the life science industry and the ever-changing regulatory scenarios. Likewise, the managing team promotes a culture of empowerment where leaders encourage their employees and trust their abilities to solve the problem. This process develops a mutually-growing environment in the company. In addition, the teams have regular internal project meetings which help them to be on track with the project. To promote knowledge sharing with a culture of continuous improvement, the management team of CliniExperts also provides rewards and recognition for employees.
“Technology is impacting all spheres of life and all industries..,” says Ashwini
According to the well-versed CEO of CliniExperts, technology is the current driving force behind the ongoing improvements in the healthcare industry. It is facilitating precise diagnosis with advanced tools for physicians, patients, and researchers. Likewise, he believes that advancements like digital records instantly enable access to patient history including dates, diagnosis, lab results, treatment, and symptoms. This greatly improves the quality of care. With smart devices, smartphones, smart-watches, and other wearable devices, the user can easily measure health conditions like ECG, sleep pattern, exercise pattern, etc. Such advanced technologies are adding a new dimensions to the healthcare sector.
Further, highlighting the potential of AI in the healthcare sector, Ashwini adds that, AI with advanced algorithms and analysis of genomics and other data will help to design medical breakthroughs for better clinical outcomes. It will be beneficial especially in the field of oncology and immunology.

We help our clients through every step of the healthcare regulatory. Licensing & commercialization process to bring their quality products in the healthcare market.

A Perfect Blend of Functionality and Affordable Biotech towards Global Society
pentavalent vaccine for pediatric application at Serum Institute.
Dr. Vinodkumar always believed that learning does not stop; this self-stimulus to gain knowledge and experience in the field of biotech benefitted to his clients and partners with many logical marvels. In the years of his professional journey, he simultaneously completed his Ph.D. and also was awarded Doctorate of Philosophy in the field of science and biotechnology at International Open University. Today, he has an experience of more than two decades starting from cleanroom design, equipment design, manufacturing, validation and setting up processes for microbial and cell culture products, and he showcases matchless and inspiring expertise.
Under the strong leadership of Dr. Vinodkumar, he and the team of Dyna Biotech have been rewarded with several awards and accolades like Business Excellence Award, Company of the year Award 2020, Adarsh Udyojag Award, Certificate of Excellence from CEO magazine, Industry Young Academic Entrepreneur Award, Global Asian of the Year 2019-20 Award, Greatest Brand of the year award and the list goes on.
The recent outbreak of COVID 19 has proven to be very unfortunate. This has also affected the outlook for
healthcare companies. Dr. Vinodkumar believes that in the wake of this pandemic, the outlook has become gloomier towards the healthcare companies. The COVID 19 has ruined all the routine operations of hospitals, diagnostic labs, Drug manufacturers, Biopharma equipment manufacturers, Healthcare supplement providers, etc. The major impact is the breakdown of the supply chain of the healthcare management process, which has caused a cascading effect on the healthcare industry. The fatalities due to imbalance in the economy of the nation caused due to Corona Disease will surely take time to heal. He also predicts that this will create a disparity in all sectors, including healthcare services as well.
Dr. Vinodkumar concludes by saying, “ We all, human society have to prove again for our human civilization. We have to be united to face this tragedy, follow the guidelines of government authorities, and keep the hope of doing the best again. ”
Dyna Biotech is a visionary organization, and the team is determined to maintain the goal of Indian Multinational brands. It envisions to ' Go Global ' and thus is stepping towards the exploration of the international market under the leadership of Dr. Vinodkumar. Currently, the clientele base is located in countries like South Korea, Taiwan, Thailand, Bangladesh, Turkey, Germany, and the United States. The team plans to extend its geographical expansion and is the leading biopharma and biotech company in the global healthcare market.
Our continuous innovation approach towards the product and services development is a key to keeping us all above the competitors.
Presently, Dyna Biotech has a stronghold in the healthcare industry. Still, in the coming years, with a strong trust and strong association with clients and vendors, it plans to cater to Food processing industries, biodiesel manufacturing firms, agro-based fertilizer businesses, dairy industries, etc. Dr. Vinodkumar adds, “ We strongly believe serving the international market allows generating foreign currency for development of the nation as well as society. ”
Apart from Dyna Biotech, the team will also focus on the growth of SV Biotech—another concerned sister branch of Dyna Biotech. S V Biotech is a brainchild of Dr. Vinodkumar, and the company deals with API manufacturing, Diagnostic kits manufacturing and will be leading new product development modules.

Rita Chaudhury | Founder Director
Redefining Traditional Healthcare Models and Transforming Medical Claim Management
The skillful team is led by Rita Chaudhury , the Founder Director of ELATE RCM , who has the experience of 18+ yearsintheInternationalHealthcareIndustry.Ritahasalways been curious about the healthcare industry. She wanted to pursue her career in medicine and earn the highest affiliation as MD. However, due to some personal issues, she proceeded to study computer programming and became an AI programmer. Prior to establishing ELATE, she worked at Jawaharlal Nehru University, New Delhi for 4 years. She always wanted to work within the healthcare system, thus she studiedUSAHealthcareComplianceandMedicalCoding.
Rita has achieved gold standard certification from the American Academy of professional coders, USA as CPC. Along with this, she is also Six Sigma Black Belt Certified from Anexus Denmark Se Pvt Ltd. She is also “Advanced HIPAA Policy and Procedure Development” certified from American Health Insurance Management Association (AHIMA), USA. She is a tech veteran and due to her expertise, she has been a guest trainer at various hospitals across the US and India. Besides, she has also authored various articles that highlight medical errors and gaps. “ I always share my knowledge with my team, which matters the most to our clients, they appreciate it and sometimes expect me to share my knowledge with them too. I happily do the same ,”assertsRita.
To keep herself ahead from the competitors, Rita always is abreast of the new changes in the industry by attending conferences,throughcontinuouseducation,readingbookson healthcare advancement, etc. Rita further said, “ One has to keep themselves updated always in this ever-changing
industry. This is the key to success, survival, and to be on the topofanychanges. ”
With the rise of digitization and increased client demands, thereisarisingneedforskilledprofessionalsforstreamlining the hospital billing procedures and implementation of compliance, which is an impetus to the growth of the healthcare industry around the globe. Rita is affirmative that due to this challenge the healthcare industry will create variousjobopportunitiesfortheseekers.However,healthcare compliance is the one, which has to be taken as a priority for patient care, as government and commercial insurances look for the “medical necessity” in the documentation before releasing the reimbursement of any claims. ELATE incorporates HIPPAstandards for the privacy and security of patient data. Medical coders and billers' job is to maintain these compliance criteria when submitting any claim to the Insurance companies. Not maintaining the security standards is resulting in denied claims due to fraudulent billing and the providers come under the radar of RAC(Recovery Audit Controller).
Ritaexplains,“ Physicians'livelihooddependsontheMedical coders and this is the reason the certification on Medical Coding from AAPC (American Academy of Professional Coders) is so important” . ELATE also acts as the Education Provider of AAPC in India on Medical Coding. ELATE continuously striving for development of the skills among the young graduates on Medical Coding, and creating job opportunitiesinIndiaandAbroad.
The Coding Education will benefit the coders with sound knowledge on medical coding, rules, and regulations including compliance and reimbursement. A trained medical coding professional can better handle issues such as medical necessity,claimdenials,bundlingissues,andchargecapture.
We focus on providing timely and errorless endto-end revenue cycle solutions to our clients.
Indian healthcare will soon follow compliance similar to HIPPA compliance as data and identity protection is crucial for everyone. ELATE aims to contribute to the Indian Healthcare Industry by sharing knowledge in creating better patient care opportunities and data protection and security. For5+yearsELATEhasbeensuccessfulindeliveringservice with quality and commitment to the client, the turn-around time for service delivery, and charges. By 2025, ELATE aims to touch the lives of youths, by developing the skills in medical coding and enhancing their employability in the HealthcareIndustryofIndiaandabroad.



Use of Biotechnology along with the study of microorganisms have significantly grown for industrial & commercial exploitation over a period. We have known for long about how milk curdles by Lactobacillus to understanding how Nitrogen is fixed and liberated in the soil to promote vegetation. But the applications have reached far beyond like even metal extraction from ores! Biotechnology is, as the name suggests, a product of the original science -viz- “Biology” that branched into Micro and Molecular Biologies and further developed for application as Biotechnology.
Biotech works on two aspects, firstly making the microorganisms work for us and secondly, modifying the structures of DNA & RNA towards a specific functional purpose including manufacturing drugs. Many antibiotics are manufactured using biotechnology. This study is rapidly gaining its ground in the industry and is fast advancing.
The only drawback here and that islike Atomic Science, Biotechnology is a double edged sword – and so can also be used for good and bad purposes. Depending upon the ethical and moral values of the society, Biotech can be a boon or bane for humanity. For instance, the pharma
industry has to set standards for quality and purpose, and have to be unidirectional in helping humanity. However, several companies are rather exploiting the tech resources only for pure commercial gains & success. This is an area that needs soul-searching by all and needs huge transformation and improvement.
As an ardent & committed member in the industry, Emmessar Biotech & Nutrition Ltd (EBNL), has always kept human well-being at the centre of its R&D, services and products. Established in 1992, the company has to date never compromised on its quality & purpose.
EBNL is a healthcare company that manufactures and markets healthcare and nutritional products globally. With rising healthcare concerns, ENBL attempts a holistic approach by fusing various concepts and principles from ancient and modern medical science. It combines the fundamental principles of Biophysics, Biochemistry, Biotechnology, and the Indian system of medicine -ie- AYUSH (Ayurveda + Yoga + Unani + Siddha + Homeopathy) to create a unique set of effective and curative products. This amalgamation of techniques resulted in the birth of a new science and technology called as VedaCeuticals™
which is the foundation of all products of EBNL.
VedaCeuticals™ was a result of the inhouse R&D for over 15 years resulting in and evolution of a new science and technology that integrated different schools of thought. This science enabled EBNL to make edible nutrients work like potential medicines, and in the process eliminating the toxic & adverse sideaffects inevitable in the usage of modern drugs.
ENBL is involved in creating products with the principal and crucial characteristics of Bio-availability, Bioacceptability, Bio-interactivity, and Biocorrectivity, and their combination has resulted in a lasting solution to the health problems. ENBL's products are related to Skin-Care & Skin-Cure, Muscle Health, Bone Health, General Health, Non-Toxic Cosmetics, etc. This wide-ranging portfolio of products addresses various unmet medical needs of healthcare. It caters to patients with obstinate skin problems, muscle problems, bone problems, and other debilitating chronic physical ailments. Presently, ENBL has over 38 products across 7 categories that can treat over 200 different health problems.
ENBL specializes in catering to diverse requirements and health concerns and is

MSR Ayyangar, Managing Director & CEO
“
proficient in delivering excellent results. The team has achieved high credentials amongst its peers and competitors alike. It aims to leverage the principles of VedaCeuticals through continuous innovation and create holistic healthcare solutions for -
•All the Sick & Suffering—all genders and age groups.
•All the chronic patients who are clueless about the cause of their disease and sickness.
•All those who are frustrated with modern but long and ineffective treatments in hospitals & dispensaries.
•All those trusting consumers who are suffering from the adverse effects of toxic drugs.
With ENBL's capability and capacity, the team's vision is to propel an evolution towards a healthcare revolution by providing simple solutions to complex health problems.
Principal Architect of Product Strategies
The principal architect of ENBL's overall business philosophy and product strategies is Mathurakavi
Srinivasa Raghavan Ayyangar (MSR Ayyangar) . MSR is the Managing Director and CEO of ENBL and serves on the board of directors. Apart from the product strategies, he is also responsible for the company's global sales & operations, driving innovative research & development, and is instrumental in worldwide marketing & business development.
MSR is an Electrical & Electronics Engineer from REC (NIT) Warangal from 1965-70 batch. Since childhood, MSR has had a natural inclination towards spirituality and human health. This resulted in a profound study of Veda, Upanishads, Ayurveda, Homeopathy, and Naturopathy - which he continues to date. Being an industrialist himself since 1984, he has witnessed the health care industry mature and face the various challenges.
Like all other industries in India, ENBL also faced the problem of bureaucratic despotism. He explains, “ When people who produce nothing—but control all others who produce everything with arrogance & irresponsible conduct—the society & the nation will have to pay the heavy price !”. Despite the setbacks, MSR
” .
with his team are continually striving to deliver the best. Since 2016, the team has developed 38 new products to meet a spectrum of healthcare needs.
MSR also shared his thoughts on the ongoing crisis of COVID-19 and termed the pandemic as a man-made and avoidable disaster. The global health crisis is being exploited by many who see an opportunity for commercial exploitation. He states that wisdom is lacking at all levels and if one carried a good sense of responsibility towards fellow humans, it would have made a huge difference. MSR is hoping for better sense to prevail.
In the upcoming years, Biotech shall rule the roost for future generations—just as IT is ruling today. As for the ENBL, MSR is optimistic about the future. He concludes, “ We are conscious of our eventful journey so far with inevitable ups and downswhich we withstood. We look forward to more challenges that will lead us towards serving the humanity at large in the healthcare field .”

The global NGS market is expected to grow exponentially in the coming years. This is contributed to the increased amount of treatment options. Moreover, more practitioners are utilizing precision medicine and molecular diagnostics now than ever before. There have been advancements in NGS platforms as well. Sequencers can now provide increased throughput and better data quality. Concurrently, capital requirements have decreased, making the technology more accessible. Additionally, payers are now compensating for tests due to reimbursement changes.
Though these are positive and crucial steps forward, they have created a dilemma for those in the industry. The diagnostic process is both laborintensive and requires specific expertise. With clinical labs effectively doubling their workforce in the next few years, the problem of managing the inevitable shortage of clinical experts is expected to appear. Analysts must give a ruling upon multiple lines of evidence, following complex decision trees and leveraging evidence weighing systems. Automation is the only solution to this problem as it eliminates human error and subjectivity. By providing guided workflows the time and labor of molecular geneticists will be cut to a fraction of what was previously presented.
Golden Helix is a company that has been extensively collaborating with its customers to illuminate what processes, workflows, and other challenges need to be addressed. Founded in 1998, the Bozeman, Montana-based company has hundreds of customers around the world with thousands of users that are provided with innovative bioinformatics solutions for both clinical and research spaces analyzing NGS data.
The software provided by Golden Helix accomplishes several things. It enables a clinician to deliver consistent, high-quality interpretations. It provides a framework for newer, less experienced clinicians.
What truly sets golden Helix in the market is its simple business model with no per-sample costs. Its products are available through an annual license fee, which allows their users to retain all the efficiencies they generate in their lab, reducing the cost per samples.
As a company, Golden Helix stays abreast of new developments. Its software is consistently updated so that customers can rest assured that they have the most current information. Moreover, experts can make sound, clinical decisions leveraging a constantly growing kit of specialty databases, publications, and algorithms that are designed to predict the impact of specific variants in the resulting protein.
VarSeq is an intuitive, integrated software solution for tertiary analysis. It can automate workflows and analyze variants for gene panels, exomes, and whole genomes. It boasts intuitive and repeatable workflows, industry-leading automation sources, two forms of coverage metrics, clinical-grade variant annotations, great visualization, and no learning curve. VarSeq is used in many spaces including—cancer diagnostics, hereditary testing and diagnosis, research, and trio analysis. This single-testing paradigm also includes an additional CNV interpretation framework. Given full marks by ClinGen, this solution is truly one-ofa kind in the marketplace.
VS-CNV is a powerful detection tool that uses an industry-leading algorithm to call CNVs directly from gene panels, exomes, or wholegenome NGS data. Coupled with VarSeq, this robust solution allows CNVs to be considered alongside the annotated and filtered NGS small variants, all within one workflow. This integration has been found to be in concordance with other methods such as MLPA or CMA, at a fraction of the cost, while meeting the thresholds for clinical validation and adoption. Additionally, by using NGS data already generated to call small SNPs and InDels variants to call CNVs, one can integrate LOH with CNV calling to distinguish Copy-Neutral LOHs from LOH events that support

Andreas Scherer, President & CEO

Heterozygous Deletion CNV Calls.
•VSClinical
VSClinical is a guided workflow that enables following the American College of Medical Genetics (ACMG) guidelines used to identify and classify casual variants for inherited disease risk, cancer predisposition, and the diagnosis of rare diseases. VSClinical includes integrated ACMG guidelines, a variant knowledge base, a standardized workflow, accelerated interpretation, automated classification, and the bonus of learning as you go. Moreover, as an optional add-on, VSClinical can follow the Association for Molecular Pathology (AMP) guidelines used for performing targeted cancer gene panel tests popular in molecular pathology labs to report significant biomarkers of clinical utility.
VSClinical had a major update at the end of 2020, boasting an additional CNV interpretation framework based on the ACMG guidelines for CNVs. The ACGS guidelines are also now available in VSClinical, which was recently announced in the
•VSPipeline
VSPipeline provides repeatable clinical workflows essential for CLIA and CAP certified analysis, creation of high-throughput pipelines, and access to curated annotation sources that are regularly updated. It is a convenient way for users in CLIA and CAP certified labs to lock down a workflow that has been designed in VarSeq. This can then be automated, mitigating the risk of human error. The creation of high throughput pipelines will benefit by automating the entire tertiary analysis process. Along with fully computed VarSeq projects, VSPipeline can also be used to generate other deliverables such as annotated text or VCF files as well as multi-tab Excel reports of filtered variants, sample, and coverage region statistics.
VSReports allows the conversion of the output of tertiary analysis into a fully-customizable clinical report. The report includes identifiers from various catalogs, descriptions of gene function from OMIM, pathogenicity, exon numbers,
coverage information, and much more. The reports are modeled off the ACMG guidelines, the de-facto gold standard for clinical reporting. These brandable reports have templates for both gene panels and trio analysis and can be used for both hereditary and cancer analysis.
As precision medicine continues to grow into more and more labs, the number of samples and subsequent data is ever-expanding. An organized system of storing this data is not only imperative but can also create a wealth of knowledge for ongoing research and future analysis. VSWarehouse is Golden Helix's scalable, multi-project warehouse for NGS variant calls, catalogs for variant assessments, and clinical reports that are built on algorithms and highpowered storage technology.
In the years to come, Golden Helix will continue to expand its global customer base, will innovate, stay at the forefront of technology, and maintain its high standards for quality and support through which it has managed to consistently thrive in the increasing competition.



Finally a technology-enabled solution that benets both the payer and the patient in the MENA region
Charlie Barlow Founder & CEO

over the last twenty years, technology has changed immensely and is positively impacting the healthcare industry in terms of driving operational efficiencies and clinical outcomes. The Middle East has historically been slow to adopt such technologies, but in primary healthcare at least, it looks like this is changing. Telehealth, the delivery of healthcare remotely through technology, is at an inflexion point when it comes to primary healthcare. Payers are haemorrhaging cash, consumers are demanding more, governments are predicting doctor shortages and telehealth provides the perfect solution for all.
Health at Hand is one such company which has realized the importance of advanced technologies for the betterment of the healthcare industry. The Dubai-based company were the first DHA licensed telehealth company, and importantly are the only independent one – with a huge focus on ‘Ethical Health’where, uniquely for the region, their doctors are not incentivised to over-medicate, they recommend generic rather than branded drugs where it is safe to do so, and have a quite brilliant app which combines live doctor video consultations, integrated doctor notes and even drug delivery. In order to retain their sustainable competitive advantage, the team of Health at Hand attend
and speak at regional conferences, frequently test competitors’products, conduct bi-annual trips to Silicon Valley where telehealth has transformed primary healthcare, and are valued ‘thought-leaders’for both regional health regulators and governments. The efforts of Health at Hand have been awarded numerous times; their CEO Charlie Barlow is a Google scholar and mentor, recently winning a place on the highly competitive Blackbox accelerator in Silicon Valley, the company won the Innovation of the Year award at the 2018 Middle East Insurance Industry Awards, and most recently were awarded a place on the United Nations sponsored C3 Impact Accelerator, endorsing the claim that they offer the most ethical telehealth solution in the Middle East and Africa.
Health at Hand have cleverly combined a market-leading technology enabled solution for the payers (with a technology stack comparable to some of the unicorn telehealth companies in the US), with an app based product that finally seeks to democratize healthcare for the consumer. With data privacy standards and medical record security that goes over and above what is required in the
MENA region, Health at Hand have had their business validated by signing a game-changing regional contract with Allianz, bringing their technology solution to 100,000s of patients in Dubai alone, paid for by their insurer. This huge endorsement is even more impressive when it is noted that Allianz are shareholders in US telehealth company American Well, who have previously secured >$500million in funding.
Health at Hand’s app based patient to doctor video consultation platform connects patients with internationally accredited doctors on-demand with a maximum wait time of 2 minutes. The motto behind the app is to enable patients to access quality advice from the comfort of their home or on the go, for an affordable flat rate fee – or even better, paid for by their insurer through commercial partnerships. Further, Health at Hand dwells extensively on consumer behaviour change since telehealth is a relatively new concept in the MENA region.
Aside from their recent Allianz contract, Health at Hand are looking to offering this service across an additional 4 regional countries during 2019 alone.
Charlie Barlow, the Founder and CEO of Health at Hand, strongly believes in the notion of ‘ethical healthcare for all’. He passionately advocates that access to quality, primary healthcare should be a fundamental human right
and not a privilege for the few. It is this social value proposition that drives all decisions within the company, believing that a deep commitment to ethical health will ultimately drive out corruption and abuse, and ensure the same access to quality primary healthcare for everyone.
It is abundantly clear that Charlie loves his work, and his huge and infectious passion for disrupting the sector is shared by his team. Health at Hand work hard to maintain a collaborative and entrepreneurial culture, with all employees having equity or equity options in the business, and all new employees encouraged to read Eric Topol’s ‘The Patient Will See You Now’on arrival, to really reinforce their impactful focus.
Culture and ethics starts at home. Adopting a mindful approach towards their own employees, with a real and active focus on gender parity (over 50% of their team are female), team members complete their own “User Guides”, specially crafted according to individuals and their expectations from the organization and their colleagues. It provides guidance on how a particular employee likes to be treated, their work-life-balance, and how to build a culture of respect, collaboration and innovation.
By combining cost saving for the payer with a patient centric consumer mobile app, Health at Hand are ontrack to deliver on their ambitious mission of ensuring quality, affordable and convenient primary healthcare is made available to all citizens of the MENA region. This would be some achievement.

At Health at Hand. we seek ways to bring the highest standard of healthcare for everyone, wherever and whenever it is needed the most.



Using AI and Mobile Dentistry to make preventive dental care the new health care fashion.

In India, 30,000 dentists graduate every year for 309 dental colleges. Yet 50% give up dentistry, as an investment in a new clinic is about Rs12 lacs and it takes about 10 years for a clinic to be profitable.
In India, South Asia, Africa, and South America 90% of the people do not have access to dental care. Even in developed countries dental care is extremely expensive. And 70% of the population in these countries suffer from a dental problem they don’t know exists.

Caddy Chair
If Mouth is the gateway to good health, then oral hygiene and dental care become the starting point of any health care conversation.
Vivek Madappa , a serial entrepreneur in exponential technologies decided to address this problem by combining two seemingly disparate ideas to offer a solution that could revolutionize dental care.
Here is the story of a start-up from Bangalore, India that has combined Mobile Dentistry with Digital Technology to launch MobiDent Digital Dentistry.


Caddy Clinic – Worlds lightest Dental Clinic in a suitcase was an ambitious project conceptualized by a team at MobiDent to build a mobile dental clinic that has “Italian design, German engineering at Indian prices”.
The Caddy Clinic has a compressor and a suction unit integrated inside a suitcase, a lightweight dental recliner chair, a toolbox, and a spitoon. The entire clinic can be transported in a small car or three-wheeler. The time take to unpack is less than 3 minutes.
For the consumers, MobiDent offers a Digital App to book a Dentist appointment. The dentists closest to the consumer’s home is matched using Ai to confirm the appointment. For the dentists, the entire reception desk has been replaced by a digital clinic management platform that manages appointment scheduling, automated customer engagement, patient reports, archiving and easy retrieval of records, billing, etc.
To give a perfect elaboration about MobiDent, Vivek stated an example of the hand sanitizer. This product has journeyed from operation theatre used by surgeons to consumers’pockets as a lifestyle product. Similarly, MobiDent aims to deliver preventive dental care at people’s homes, instead of a clinic. In simple terms, MobiDent is the Uber of Dentistry.
When people hear dental care they associate negative feelings of fear, pain, lack of time and expensiveness. With the growing trend of “selfies”, social validation and vanity,
MobiDent is focused on promoting preventive dental care as either a healthy habit or special occasion habit. For the health-conscious MobiDent offers family care service and for socially conscious, MobiDent offers dental care for special occasions.
MobiDent over the last 4 years has organized dental camps at more than 400 organizations, 20 hospital OPDs, 300 homes and treated more than 65,000 people. MobiDent team regularly organizes CSR activities at old age homes, orphanages, and NGOs. Furthermore, to ensure consistent quality the dentists are trained at MobiDent Academy for Digital Dentistry (MADE). This academy tracks as well as measures the knowledge and skills of every dentist. Only dentists who have completed 2500 procedures are certified for home visits.
The technology-oriented CEO of MobiDent believes that for a revolution in health care the medical care needs to shift from corrective care at hospitals to preventive care at homes. Hospitals only offer sick care. He believes the future of health care will see an attitudinal & behavioral shift with consumers taking responsibility for their own health. When data is digitized, the cost of storing, transfer, retrieval, and analysis into information greatly reduces. Consumers will start using IoT wearable to track and monitor their vital signs. These advances in technology will ignite a massive shift to preventive healthcare, selfmedication and lifestyle changes to stay healthy to avoid expensive hospital visits.
MobiDent’s vision is to make dental care accessible to 200 million people by 2022 at less than $10 in areas like India, Asia, Africa, and South America.



Saving Lives By Virtually Sharing The World’s Best Clinical Practice
the fight against COVID-19. The platform is secure and has been deployed in over 50 hospitals around the globe, completing more than 300 surgeries each month, in 30 countries. Proximie is fundamentally changing the way clinicians train, interact, apply their expertise, and provide optimum patient care now and in the future.
Building a business that aspired to change the paradigm of surgery, whilst still a trainee surgeon with a young family, was ambitious and not without its challenges, Dr. Nadine concedes.
" Disruption in healthcare is complicated and anyone who says it’s easy or straightforward has probably never experienced it ,” She explains. But if it’s solving a problem, then the adoption can be swift and decisive.
" I think when we first set out there was understandably some skepticism about whether or not we could match our ambition to change the paradigm of surgery! There was also concern about whether or not we could build something intuitive yet capable of supporting the type of precision that is required in an operating room. Would Proximie end up being too otherworldly or cumbersome from an integration perspective? ”
Dr. Nadine adds: “ We knew we had to build something for the here and now, as well as for the future. It had to answer an urgent need and have the potential to both decrease costs and increase the efficiency and quality of care. That was the dichotomy we had to overcome. ”
Being a surgeon has been instrumental in the Proximie story to date, according to their founder, with Dr. Nadine suggesting the insight she has accrued as a clinician has provided her with a crucial overview of a complex industry. " I’m a frontline surgeon that has been exposed to the complexities of healthcare systems ,” Dr. Nadine says. “ I understand the challenges around behavioral change, and how sometimes the adoption of new technologies can be slow. I also understand what may or may not work, within the healthcare environment because I have experienced it first hand. That has been invaluable ." She adds: " Proximie was born out of a need, and my ambition as a surgeon was to find a solution and scale it using technology ."
Apart from being a surgeon, Dr. Nadine reviewed several technological elements ranging from the role of genomics to advanced robotics as part of her role on the Royal College of Surgeons “Future of Surgery” Commission. Having a keen eye on future technological advancements has served her well to date, but Dr. Nadine concedes COVID-19 has been a catalyst for the rapid adoption of new technologies, and that the pandemic is having a profound impact on healthcare systems all over the world.
“ Necessity is the mother of invention, which is particularly palpable within the current COVID-19 climate ,” Dr. Nadine says. “ We have seen Proximie can help form the basis of a responsive approach to some of the challenges being posed by COVID-19 .”
We are changing the way clinicians interact, apply their expertise, and provide optimum patient care, now and in the future.
In many respects, Proximie was built for a pandemic of this nature, due to its easy integration and the fact it works at low bandwidth, with existing or easy to resource hardware, which has meant the platform has been able to be installed across multiple sites to support during the acute phase of the pandemic.
Dr. Nadine says: “ We must use a pragmatic, collaborative and innovative approach to meet the challenges presented by this viral pandemic, and that has meant us being even more agile than we were before. There is an urgent need to incorporate integrated technologies like Proximie into routine or complex practices, because we can seamlessly maximise healthcare resources, scale the delivery of expertise, reduce transmission of the virus, and ultimately ensure that every single patient has access to the best possible care, regardless of where they are in the world. ”


n the current healthcare scenario, value-based care has
become increasingly dependent on technology since modern digitization has significantly augmented it. Emerging advancements like AI and APIs assist in meaningfully integrating data to deliver a high quality of care. Likewise, it helps in reduction of hospitalizations, ER visits, and nursing home visits, which ultimately decrease healthcare expenses. However, according to Git Patel , the CEO of SPAC International , the present technologies still lack some intelligent features which only a human can do. One can say, technology is not fully developed yet to act as a human being. To further elaborate, he gives an example of a patient using wearable to track daily activities. In this case, if the patient forgets to wear the device, then his complete efforts go waste. This applies to every patient utilizing technology. Therefore, to avoid such complications and disengagement of patient and technology, Git’s company brings human assistance as an essential partner of patient as well as technology.
Sargas Pharmaceutical Adherence and Compliance International (SPAC International) provides the technology and human touch, which go hand in hand, delivering the opportunity for clients to provide the best available care for their patients. Its FDA approved Mobile Medication Treatment Monitoring applications, along with the compassionate staff, help patients stay on their medications
Git Patel CEO
and reduce the progression of their disease. Its team has developed intuitive solutions, which enable the aggregation of data collected from various stake-holders in the healthcare ecosystem to deliver better quality of care and reduce healthcare costs. Further to provide more personalized experience, it works with Medicare and Medicare patients and contracts with their physicians to help bring chronic care management and remote physiological monitoring of patients’vitals like blood pressure, blood glucose, and pulse oximetry. This work enables the company to offer a value-based care for senior citizens, helping them to stay engaged with their health.
Delivering quality care comes with a strong sense of responsibility to comply with the healthcare norms and current improvements. To train the staff on regular improvements in its healthcare platform, SPAC International offers individual hands-on training sessions to each and every team member. It also conducts a rigorous training process after they join the company and regularly updates them with the latest industry changes. It also has a structure of annual and quarterly performance reviews. Similarly, the leading healthcare solutions provider performs the assessments of staff members and checks if any extra coaching is required. Then, according to the requirements, SPAC managers immediately start offering
trainings to improve the skills of the members and help them understand the product for effective utilization.
With its dedicated team of members, SPAC International has developed innovative software and mHealth applications to keep physicians and patients engaged from the time a script is initiated through the entire treatment process. This team approach to treatment management enables cancer patients to reap maximum benefits and get the best outcomes, while reducing costs. Additionally, the CEO and his team have developed a HIPAA Compliant Cloud Portal which allows real time patient’s critical health information exchange among various providers.
Presently, as the CEO of SPAC International, Git and his team are following a path to utilize available technology thereby assisting the healthcare stakeholders deliver highquality patient care at significant reduced costs. He also ensures that the prime goals of the company are aligned with its mission of offering economic healthcare. Moreover, Git possesses expertise in developing various revenue streams like in office dispensing, ancillary services in hospitals, specialty health clinics, and cancer centers. In his vast career span, he has consulted with various cancer clinics and hospitals around the country for the cancer service line development. To enhance the skillsets and empower learning in the healthcare industry, Git and his team also participate in various technology conferences throughout the country. He attends and marks his presence
in annual business summits, which enables SPAC to stay at the forefront of the healthcare technology arena. In these healthcare conferences, Git also provides his experienced insights to fellow board members of various organizations. Similarly, he learns from their experiences within the healthcare space.
Git believes that there are certain obstacles like the competitive and rigid nature of healthcare sector. Such environment prevents SPAC International to enter partnerships with different healthcare organizations. According to Git, several parts of the healthcare industry have not been entirely open to the existing opportunities. SPAC’s platform has the capabilities to bring new opportunities but the current rigidity in the healthcare industry is acting as a barrier for them. However, Git prefers to keep moving forward and tackling each and every challenge coming in the way. Being a passionate leader, he empowers development by keeping everyone in the loop from patients to physicians to the case managers and board members, making sure that everyone is treated with respect and dignity.To continuously focus on SPAC’s mission, he considers being straightforward, honest, ethical, and respectful towards everyone’s needs. He also encourages his team to imbibe these morals while dealing with patients. Likewise, Git also ensures that managers must follow the same principles to interact with their teams.

Automation developed through Sargas Chronic Care




