PBPM 24'2018, 52-68
UDK 577.354:535.514:681 .785.3
PHOTOBIOLOGY AND PHOTOMEDIC?NE
ACCENTS OF THE HUMAN BODY ELECTROMAGNETIC BALANCE REGULATION SYSTEM
S.A. Gulyar
Dr. Sci. (Med.), Prof., Leading Researcher
A.A. Bogornolets Institute of Physiology of NASU 4 Bogomoletz St., Kyiv, 01024, [7)(raine International Medical ?imovation Center, Kiev, Ukraine tel.: +38(050)411-16-32 e-mail: gulyar@zepter.ua ORCID 0000-0003-2128-7656
The presented analytical resiew includes data abo?it the current state of knowledge on the electromagnetic ecological background influencing all living organisms. It is demonstrated that a non-specific morbidity can result from an electromagnetic imbalance and free-radical oiierloading resulting from disturbed ecology. We postulate tlie existence of a separate functional system of the electromag-netic regulation in the organism, and a working concept of phototlierapy application is formulated. It is based on the possibility of rising acup?incfüre points for energy compensation from electromagnetic waves of a biologically necessary range in the system of their conductors in the organism. This system can be considered as a tool for transmitting polarized electromagnetic waves in a visible light range.
Organs subjected to an electromagnetic imbalance because of an excess of the biologically inadequate irradiations and serving as targets for peroxidation-induced influences, i.e., neuroliormonal and immune regulator)y systems of the organism, are qualified as recipient zones. Subsequent electromagnetic stimulation or modification of the functions of the recipient zones result in positive curative effects; combination of the latter with local reparative processes allows one to provide positive clinical sliifts in persons subjected to the respective treatment.
Natural possibilities allowing one to compensate deficiency in electromagnetic waves of the "solar" range are limited. Applications of PILER-light generated by BIOPTRON-type devices can be considered an adequate alternative. Combined application of local axid systemic electromagnetic influences of the waves of a biologically necessary (visible light) range with the rise of the principles of light therapy concepts constifütes a crucial feature of the modern approach.
At present, problems of,iudicial and medical legalization of light- and color therapy, questions of the main mechanisms of the effects of PILER-light, a field of the medical reasons for its application, first generations of the curative modes, aiid color tlierapy curative programs can be considered settled.
Among o?itstanding questions, in general directed toward the expansion of application of the PILER-light therapy technologies, the first place is occupied by a necessity for the development of new experimentally grounded curative programs and antipain techniques provided by color therapy.
Key words: BIOPTRON, PILER-light, electromagnetic waves, electromagnetic technology, electromagnetic imbalance, phototherapy, color therapy, polarized light, acupuncfüre points, energetical meridians, pain, imrnunity, irisceral systems
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JH{y?d11 (2ii?H their state. It follows that in the pathogenesis of many to electromagnetic ecology
MillionsofyearsoflifeonEarth,föesubsequent;"eticaestab':ii;at'i:"nTasi".' development of mammals and humans occurred xn AS 311 electric potential difference OCCllrS in gellconfüflons Of rela'fjvel3' consfanf eXPosure fO elec- eral on the Earth (föe stratosphere - the surface) the tromagnetiC fieldS (electromagnetic WaVeS) that had same for the human body (head - feet), static electricity iiafural flucfuaflons depenfüng On föe sl)ace and SOlar which is accumulated mainly on the skin determine-s activity, the Earth and the Moon rotation. Accordingly, the effect of electrical charges on the skin structure, forsucli animportant environmental factor there could and internal OrganS [2, 7, 7i3, H1B fluctuation, for eXnot be developed physiological mechanisms of adapta- ample, at clianging weather conditions distort nerve tion. It is also physiologically reasonable, the existence impulses from the skin receptor areas, causing various of mechanisms that utilize electromagnetic energy to deviations of aritoiiomic functions. These phenomena ensure the needs of the current metabolic processes. are evident in indivifüials with hypersensitivity to Inotherwords,electromagneticbackgroundhassome electromagneticdifferences(meteopaths).?should influence on the organism functional systems, and its add that there are electromagnetic fields of the brain, fluctuations in the range greater than natural fhtctu- heart and other organs, that interact with the magations (magnetic storms), cannot help but reflect 011 netic fields of the Earth and artificial (man-made) states of the organism, pre diseases, immunodeficiency and diseases, a significant role may play electromag-
electromagnetic fields (table 2). There are described many evolutionarily developed adaptive mechanisms of of body regulation functions, that depend on the electromagnetic environment: electromagnetic field orientation, presence of "biological watch" (coordinated with diurnal variation of the geomagnetic field, or time-shifted depending from latitude to latitude), "group navigation system of birds" and et al. [69]. One consider that the biorhythms of functional systems determine the quality of the reproductive function, rate of aging, and development of life-threatening disease (malignant tumors, diabetes) [11].
Empirically, perhaps, without fully realizing, the electromagnetic nature of disease, the ancient Chinese, Tibetan and Indian healers have developed technology options of acupuncture based on mechanical stimulation of structures related to the regulation of the body functions [42, 50, 57, 59, 60, 66, 68, 74, 79]. If you do not take into account the religious and mystical layers, this technology has a q?iite slender structure from the position of electromagnetic supply of the fundamental biophysical processes proper functioning. This process has a history of evolution lasting millions of years, as identical acupuncture points are revealed in humans and different mammals.
An important proof of the existence of the reaction zone, referred to as acupuncture points, were föe results of experimental studies of analgesia. During formalin model on animalswe obtained confirmation of the role of poly- and monochromatic polarized light application at E-36 acupuncture point [55]. We also revealed participation of opioidergich analgesic system, indicating on association of acupuncture points and structures located in the central nervous system [53] (Fig. 1).
So far, the hypoföesis is formulated [50] tlxat the acupuncture points can be considered as electromagnetic waves receptors, perceivinB them for further transport to various orgaxis and tissues through the meridians that are the best conductors of electromagnetic waves in comparison with the surrounding tissues. Subsequent studies confirmed föe possibility of non-contact conduct of the electromagnetic waves of microwave and visible ranges of the acupuncture points to the different levels of the central nervous system [13, 24, 48, 53, 65, 67, 74] and it is found that at pain syndrome effect reaches the level of endogenous opioid systems in the brain [48]. This, parallel to anatomical structures, electromagnetic or meridiaii "Skeleton" is probably a quite workable form, because in the effectiveness of acupuncture no one is in doubt now. There only remains the ancient prejudice of the doctors standing on the positions of the European classical medicine, about the absence of a material substrate for the eastern technologies.
Electromagnetically sensitive acupuncture points have a number of distinguishing feafüres, in comparison with the surro?inding tissues, and can perceive electromagnetic waves of different frequencies (light
from different sources, microwave, that of very high frequency, man-made radiation, although a natural stimulant is a natural solar spectrum), ca?ising subsequent resonant responses from atomic and molecular structures, which have functional connection with these points [50, 73]. Moreover, depending on the natural variability of föe Sun and probably lunar phases affecting terrestrial magnetism, the acupuncture points may change their sensitivity, becoming "open" and "closed".
Recently, there are obtained data on the collagen semiconducting properties, which in combination with water molecules .ioint into cluster structures defines liquid crystalline properties of föe connective tissue. This approach, based on the above concept, explains the discrepancy between anatomical and functional efficiency, uncertainty of the concept "meridians" or "channels" in terms of oriental medicine [36]. The main grounds of the authors of this approach can be formulated as follows:
* The system of acupuncture points, meridians and constant electromagnetic field of the body belong to a holistic system of liqriid-crystal fibers of collagen, which is the basis for connective tissue.
- Meridians - are oriented collagen fibers, surrounded by layers of bound water, provide permanent proton conductive pathways for rapid interconnection of all structures of the body, providing its functioning as an integrated system.
Fig. 1 . The effect of naloxone blockade of opiate receptors on tonic pain:
Duration of the pain response (pain focus licking) observed for 60 min after influenceon E-36 acupuncture point inthe animals of the control group (placebo) and the four experimental groups receiving only Pilar-light and in combination with doses of naloxone 1, 5 and '10 mg/kg. The figure illustrates the existence of the objective biological reaction in response to the contactless light application on acupuncture point, the existence of the connection between a remote area (point E-36 is located on the upper third of the leg) and subcortical analgesic centers, as well as the opportunity to receive clinical outcome (analgesia). Blockade of the receptors of the brain opioidergic system is illustrated by analgesia reduction at increased dose of naloxone.
-The liqriid cxystal "network" is involved - in qriick response to electromagnetic waves; - the ability to respond to the trace substances (homeopathy);
- the formation of hyper-reactivity to allergens; - emergency responses to damage.
- The liquid crystal "network" provides a link between somatic and neural structures.
To provide the mentioned processes, peculiarities of collagen structure are important, whiclx consists of chains of molecules of tropocollagen, length 280 nm, which are oriented longitudinally parallel. These molecules do not mutually adioin, there is a gap between them and the a4iacent molecules osierlap slightly. The length of the molecules is 4.4 times larger than its diameter. Tropocollagen triple helix is stabilized by hydrogen bonds between individual chains [63].
It is exactly this structure, which is the most convenient for ?ineven transmission of electromagnetic signals, i.e., for facilitated in the longitudinal directioii. The ne'hvork of collagen and elastin fibers, available in the connective tissue can probably cart7 both longitudinal transport of signals, for example, along the limbs and body, and irradiation of their part into the tissue depth. Location of the connective tissue arorind föe nerve structures improves the signals broadcast into nerve fibers, which may facilitate the invofüement of the nervous system in the generalized network reactions.
On the other hand, it is assumed tlxat on the gro?ind surface there exist magnetic aiiomalies (geo patliogenic) zones with different physical characteristics in comparison to "standard" [6, 7, 66]. Figuratively speaking, one can call them "acupuncture" poixits of the earth, because they (similar to acupuncture points) are areas with altered geophysical parameters (the geomagnetic field, the electrical conductivity of the soil, the electric potential of the atmosphere, the level of radioactivity, etc.). The role of tliis factor has not been studied completely, altho?igh it is considered [9, 56], that it might become one of the additional conditions of tlie human state electromagnetic modification (generating of stress reactioiis responses).
The iiifluence of Earth's magnetic field fluctuations on heart rate can be illustrated by the results, we obtained during the transatlantic voyage "Ukraine-Antarctica" [37-38]. As singled o?it, the magnetic field fluctuations determine similar changes in heart rate, the dynamics of which in its fürn cliaracterizes the balance of the a?itonomic nervous regulation of the cardiovascular system state.
In this aiticle, we are not going to consider in detail the extensive factual material about the influence of iion-polarized electromagnetic microwave range of the physiological mechanisms of subsequent reactions at the molecular, cellular, organ and system levels. Works by ND Devyatkov, MB Galant [8] YuPLimansky (1990) [50], Y. Khurgin, IV Rodshtat, DS Cliyarnavsky,
AS Efimov and SP Sitko (1993), SI Gerashchenko [14] IZ Samosyuk et al. (1999) [73] forind out that even inadequate for organism electromagnetic waves transmit to the body information about the rhythms of electromagnetic field. This refers to the millimeter range (frequency, iiitensity, etc.), with which people coexist only a few dozen years. Its normalization is a precondition for the subsequent recovery of the function and strucfüre of individual cells and the organism as a whole. Tlie transmitter of the electromagnetic field parameters to molecules and cells are most likely water molecules and polypeptides (cytomedines) as the main factors of intercellular interactions.
Eno?igh data has l»een accumulated on the effect of laser radiation at different wavelengths [39, 40, 61, 70], which is characterized by a narrower therapeutic strip, borderiiig with destructive effects (depending on the time of exposure, power, absorption). Nevertheless, the low-energy laser liglxt having a hixf density of 0.1-1 W/cm'2 carises photochemical reactions: bio stimulation at the expense of photo induction (influence on cell membranes, activation of cellular metabolism, DNA synthesis, RNA, singlet oxygen formation, etc.) [4, 12, 15, 26]. Bio resonant effect [14, 61, 78], which is föe leading in complex reactions in response to exogenous electromagnetic vibration, is achieved by empiric selection of shape and frequency of electromagnetic oscillations. The authors believe that the physiological homeostasis is achieved in föe result of physiological frequency spectrum increase and maintenance of the relative timing of the vario?is wave processes. Modern views on the pl'iysiological mechanisms of electromagnetic waves actioii you may found in [51, 54].
Influence of physical factors, having an electromagnetic component (extreme temperafüres, magnetic and electromagnetic fields, microwave, light), on biological strucfüres are largely focused on the cell nucleus [76]. According to AS Derdi [75] and VGShahbazov [76] molecular complexes that make up the system of the cell nucleus, function in a living cell at "biological" temperature as a kind micro oscillators. They convert the energy of the thermal vibrations of the water dipoles into electric charge of the nucleus aiid electromagnetic radiation in a wide frequency range within the cell and beyond. This energy generator provides many cellular functions, including cytoplasmic transport of substances, their exchange and inheritance implementation. The maxinmm development, from orir point of view, tliis mechanism reached in deep phosphorescent fish, stingrays, eels, etc. Bioluminescence can be regarded as evolutionary hypertrophic generating property (bios>rnthesis) and transport of electromagnetic waves to compensate the lack, which occurs in underwater environmental medium.
There are three types of electromagnetic relationships (electromagnetic control) in the body - nervous regulation (the relationship of the central control system with the peripheral executive receptor elements),
PBPM 24'2018 PHOTOBIOLOGY AND EXPERIMENTAL PHOTOMED?CINE
autonomo?is connections between elements (cells and macromolecules) aiid signals, given by the control system to all tlie elements at the same time [68]. We assume the presence of signaling schemes of the central nervo?is system of the type "to all-over": in the periplieral ganglia, the endocrine glaiids are "receivers" that are configured on föe "emergency" rate, and provide signals retranslation to the actuators at the corresponding frequencies.
Regulation of electromagnetic endoecology
Therefore, by now, there are accumulated enough data for credible approval of the existing dependence of highly organized living beings (as unions of atoms and molecules), including humans, on electromagnetic background of Earth. Electromagnetic waves, changing the fullness of electromagnetic energy of the body frame (Fig. 2), evoke the appropriate resonances and fluctuations of the electrical potential in its molecular structures, participate in functions ' control and ensure the electromagnetic homeostasis maintenance (eq?iilibrium). Excess of reactions on waves ' physical characteristics (intensity, shape, frequency, length, etc.) above physiologically required level lead to incoordination of nervous, imrmine and hormonal regulation.
Fig. 2. Electromagnetic skeleton of the body, defined by a lightweight electromagnetic conductivity: Ears, hands, feet are zones of high concentration of electromagnetic receptors (acupuncture points)
In 'Fact, it is possible, with certain assumptions, to imagine the existence of a separate functional system that regulate electromagnetic balance of the body (FSREB) [27-31], containing all the ingredients of a classic functional system, according to PKAnokhiii [1]. The hypothesis of the possible existence of "ecoceptiv sensitivity" suggested byYuPI,imansky, meaning its ability to monitor changes of the environmental factors (electric, magnetic fields, etc.) wiliich do xiot carry information that requires immediate sensory signal [50]. Functional systems of the body are formed I?[) of dynamically mobilized structures in the scale of the whole organism, and on their activities and the result does not reflect the exceptional impact some type of the involved anatomical structures. Moreover, the components of particular anatomical accessory are mobilized and involved in their assistance to obtain programmed result. According to the interaction principle, they are combined to achieve any adaptive result, for example, stabilization of blood pressure in the circulatory system, nervous and endocrine systems. Therefore, at systematic approach, we focus not on some anatomical feature of one component invofüed, but on the principles of many components organization from many anatomical systems with indispensable result of this extensive system activity [1 ]. The strucfüre of the functional system of electromagnetic regulation based on the above factual material of light therapy, the example sliown in Fig. 3. From our point of view, workability of such a system will depend on the quality of the external electromagnetic flux (biologically adequate wavelength range, polarization, presence of evolutionarily developed meclianisms for utilization).
As shown in Fig. 3, starting stimulus in the form of polarized electromagnetic waves within the olitical range of constant magnetic field, radiation in the infrared or millimeter wave bands, as well as invasive mechanical irritation (needle stick) caiise activation of poly modal (electromagnetic sensitive) receptors, i.e., acupuncture points. Transmission of electromagnetic signal is carried out through the best ways of their conductivity (meridians and connective tissue stroma). In addition, there are processes of molecular pliotoreception described separately [29, 52, 54]. Stimulated by electromagnetic signals, neural strucfüres and electro dependent processes stimulate "decision taking" and determine the result of the acceptor action (visceral organ). As recipients can be considered organs, that experience electromagnetic imbalance due to the excess of biologically inadequate radiation, suffering from congestion of free radicals (lipid peroxidation), primarily, ne?iral hormonal and immune regulatory system. Tlieir functional state, after electromagnetic exposure, determiiies the (positive or negative) feedback, that is changes in electromagnetic conductivity of acupuncture points. Such self-regulation (harmonization of the existing energy background with the demanded) extend on the amount of energy absorption, regulated
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Fig. 3.General cheme of functional system of electromagnetic balance regulation by the structures that provide electroii'iagiietic reception. This process also depends on geomagnetic, solar and luiiar activity.
It is important to mention the significance of polarized electromagnetic waves, as their polarization is the main factor causing a stable biological effect. It should be noted that the above given scheme should be regarded as a working hypoföesis, as some of its ?inits do not yet have sound anatomical and physiological characteristics. However, in recently completed (2002) anatomical studies [49], there was performed the identification of acupuncture points on the ?ipper limb by sonication showed föeir 80% coincidence with interstitial connective tissue formations (inter muscular, extending along the surface and into depth). Tlie auföors concluded that föe meridians can be treated as a structure consisting of connective tissue that connect the superficial and deep formation, participating in the transfer of biophysical changes occurring under the action of the needle. There are also detailed anatomical data showing the connection of the nerve stiauctures and acupuncfüre points. There are found anatomical correlates (mostly nerve trunks) of 24 primaries, 28 secondary, 27 tertiary and 31 non-specific acupuncture points. We carried out identification of 110 points in two hundred subjects [10]. This is meningful for understanding the integrative role of interstitial tissue in providing physiological effects distantly arising at acupuncfüre. Research of biologically active zones
relations to the surface of the human body allowed to allocate zoiies with "wave representation" of individual organs [45-46].
On the other liand, by biophysical modeling meföod [78] we established physical grounds of the existence of coherent electromagnetic field of the body ("electromagnetic framework") in the millimeter range. There are four groups of facts, which convince the author. First of all, a pronounced presence of the electric fields intensity in cell membranes (about 10-5 V/cm), which is created due to tlirougli membrane ion transport. Second, frequency of the cell membranes oscillation, determined by their mechanical properties, lies within the range of 1010-1011 Hz. Third, the presence of skin, separating regions witli different refractive indices, separates tl'ie inner area witli a large refractive iiidex, which supports more intensive radiatioii density at the expense of internal reflection. The fouith factor, which conditions a possibility of a coherent field, is the identity of the genome of all somatic cells of a particular organism. They can be regarded as active centers providiiig genome transformation into a spectrum of electromagnetic radiation. From the standpoint of the calculation of limited cycles, we showed that the meridians are (functionally) coherent running electromagnetic wave. Wave conductor properties of meridians define their internal transport in accordance with the laws of nonlinear optics for a closed resonator filled with nonlinearly absorbing medium with active
centers. Minimum of losses is determined by the fact that the angles of waves that falls on the inner surface of the skin sho?ild be less than the angle of the total internal reflection for the environment. A direct experimental proof of the electromagnetic nature of the meridians is registration by the authors of a non-equilibrium component of electromagnetic radiation of the organism in mm-range. The complex of equipment with its inner noise level for the frequency range wiföin 53-78 GHz in the region 5-10-23 W/Hz-cm" allowed to register radiation areas of the human body and its dynamics in the mm range. The value of the non-eqriilibrium component (radiation from the biologically active zones) varied in the range of 10-23 - 10-21 W/Hz-cma2
In addition, the proven clinical efficacy of PILER-light also gives grounds to confirm the hypothesis mentioned above, and it is impoitant to determine the future direction of its deep studies of indiiidual units. For example, the "narrow" places, which will require urgent investigation, in o?ir opinion, are the features of electromagnetic signals transport into connective tissue and the process of transmission them into nerve structure. It is important to pay attention to photo dependent processes at the level of cellular membranes and organelles, which should liave a parlicular response to electromagnetic waves of optical range. The influence of electromagnetic and contribution factor may be the basis for clarifying biophysical mechanisms of many electro dependent processes in cells and their systems.
The main indicator of the FSREB activity, which can be determined indirectly, is the quality of the internal organs functioning aiid visceral systems in general. It depends on the iiature of the source of the organ electromagnetic background or features of external action, which are the resulting of wavelengths, their power and exposure. From the available empirical observations, we can say that there is a nafüral self-regulatioxi mechanism of the circulating volume of electromagnetic energy. For example, from clinical practice it follows that at different times of the day there is a different activity of the acupuncfüre points as the receptors, wliich receive electromagnetic waves. This is attributed to sun exposure and biorliythms (depending on the phase state of the Sun and the Moon). At daylight, when we observe a high level of electromagnetic energy falling on the surface of the body, many acupuncfüre points are "closed" (become less susceptible to excess energy), in tlie dark - "open." Moreover, at diseases followed by increased peroxide oxidation (which usually happens) in the respective systems of visceral tissue there increases metabolism and power consumption, there appears an energy deficit. At the same acup?incfüre points, "responsible" for the particular organ or segmental area, "open", and become stroiigly susceptible to electromagnetic factors up to respond to meclianical stimulation. At this time, these points become sensitive and you can easily determinethem on yo?ir body.
From the standpoint of light puncture, it becomes clear and understandable the existence of areas ivith a high concentration of biologically active points on the body (face, ears, hands, feet) as the sites tliat in the process of evohitioii has always been open to solar (light) electromagnetic waves (unlike protected by fur or clothing). Alongside, it is observed a general biological principle of multiple redundancy (backup) in case of traumatic injury of one of their sites.
The above hypothesis of the FSREB explains the noii-correspondence between the anatomical and functional efficiency of "meridians" or "channels" concept in terms of oriental medicine [62]. In accordance with this approach, the system of acupuncture points, "meridians", as well as permanent and variable electromagnetic fields of the human body interact with the holistic system of liquid crystal fibers of collagen, which is the basis of connective tissue.
On the effectiveness of the considered working FSREB hypothesis may also indicate tlie effectiveness of BIOPTRON-color therapy method, which is based on the influence of electromagnetic waves of different lengths on biologically active zones (points) [3].
We should say that the existence of a system that regulates relations between the body and the external electromagnetic field with more or less empiricy is always under consideration. In particular, R Becker [2] described a "slow electromagnetic system of regulation in veitebrates", which is associated with a peculiar distribution of the surface potential (Fig. 4). The a?ithor presents evidence that this system controls tlie speed of electrical impulses extension in nerves, transmits to CNS information associated with pain and mental functions. He suggests that this system controls the general behavior of animals and that through it is carried out the influence of föe magnetic and electric fields of Earth on animals and humans [69].
Fig. 4. Distribution of surface electric potential on the human body and lizards [65]
An interesting approach ofVGMakats et al. [58] is based on measurements of the electrical conductivity of biologically active zones. There are revealed the interdependent self-functioniiig energy cycles, especially the regulation of vegetative homeostasis and the interaction between the individual functional systems of the body. This allowed föe authors to put forward the idea of the existence of "functional-energy system of biological objects (Makats effects)."
Violations of tlie harmony of tl'ie electromagnetic interactions of tlie external and internal enirironment determine föe occurrence of various types of patl'iology. The resulting deformation of this body's electromagnetic field can be recorded using Kirlian effect [47]. Modern methods of the humaii body electromagnetic radiation measurement in mm range is already allow to detect the presence of a non-equilibri?im component [78], i.e., "Aura" that characterizes the individual peculiarities of föe body functional state (Fig. 5).
@@)@«i::
Fig. 5.Plant bio field reaction in response to the impact of 1luman bio-field [77]:
A - human generation thoughts of love and kindness to the plant;
B - plant responses to positive ?emotions?;
V - generation of human thought ?IJI cut you?;
T - plant responses to negative ?emotions?
Electromagnetic exoecology and its significance for the organism
Let us coiisider the relationship of organism with the environment from a position of "usefulness" of ceitain types of electromagnetic waves. Urbanization, a companion of life in the modern world gives rise to many electromagnetic wavelengths not found in the evolution. When applied to the "usual" waves, for example, solar spectrum, we can talk about a possibility of specific adaptation (accumulation of melanin in the skin of Africans, blond color for northerners, etc. ) and non-specific neuro hormonal activation of antioxidant system to block lipid peroxidation. Then for historically "new" influences, there are observed different and usually negative variety of responses. Generally recognized term "electromagnetic pollution" (electromagnetic smog) indicates patterns of adverse effects of the electromagnetic field increasing with exposure and frequency characteristics.The greatest amount of information is available abo?it föe biological effects of microwaves, which is expressed iii the disorder of the central iiervous system, followed by dysfunction of xisceral systems up to the heating (destructive) effect.
The consequences of an adverse effect on the organism of environmental factors can largely be reduced to common resultiiig pathophysiological mechanisms. It can be described as an overload of the antioxidant system, forced to neutralize tlie excess of free radicals generated by botli external and internal environments. The final process is the increase in lipid peroxidation (oxidative stress), during which there occurs destruction of cell membrane lipids, enzymes, disintegration of regulatoiy influences, mutagenicity increased and other negative phenomena, which ultimately determine sickness rate and life expectancy (Table 1).
Two
ENVIRONMENTAL (PEROXDATION) STRESS ELECTROMAGNETIC MISBALANCE
FREE RADICAL INTOXICATION
ENHANCING PEROXDATION
INSUFFICIENCY OF BOLOGICALLY DEMANDED RANGE EM WAVES
EXCESS DISRUPT RANGE EM WAVES
A second, less sfüdied, but not less importaiit aspect of determining the state of health is föe maintenance of normal background levels of electromagnetic stimulation of biochemical and biophysical processes. The example of the difference in the quality of plants growth, grown in the basement and in the sunlight, once again convinced of föe need to provide every earth living being with insolation, the intensity of wliich cannot be below a certain critical value. However, the electromagnetic imbalance, everywhere overtaking each of the members of a modern society, give evidence of isufficient obtain, by many of them, of electromagnetic waves of necessary biologically range (insolation), and an excess of the action of destructive electromagnetic influences. In fact, we speak of substitution for the body of one wavelength for another, which "taking" a somebody else place (ecological iiiche) "parasitize" (causing physiologically iiiappropriate resonant and thermal effects) aiid briiig destabilization where cellular structures are waiting for natural (due) wave.
These technogenic electromagnetic fields have a simpler frequency organization and pulse structure; however, they have several orders of magnitude greater intensity and uneven localization in space [62]. As damaging electromagnetic waves are in uncontrollable excess, the list of adverse effects is hard to predict, but in any case, these changes could become irreversible.
The significance of the new urbanized electromagnetic environment at home is very important. According to measurements carried o?it at the Institute of Terrestrial Magnetism and Radio Wave Extension [71], "a characteristic tension on the surface of the füiman body varies from 20 to 200 V/m, reaclxing on top of 1000 V/m. Wearing natural clothing gives almost no
PBPM 24'2018
effect oii these statements. Clothing made of synthetic materials when it is removed, or iiatural movements creates strengtli values up to 14,000 V/m, contributing to the development of cardiac arrhythmias. The same refers to slioes made of syntlietic materials - the sole while in contact wifö asphalt, at each step, generates a voltage of 10-20 kV. With small dimensions of standard flats aiid excess of furniture in föem of non-natural materials, surrorinded by wiring each dwelling fürns into a ball of electromagnetic fields, each protr'i'ision of furniture - in the storage of kilovolt static charges. Frictioii of tires on the asphalt fürns a mosring car in a good capacitor".
From this non-equilibrium state tliere can be only two alternatives: the first - leaving the radiatioii zone, reducing the length of stay or screening (with attenuation coefficient over 2 growing shortage of natural electromagnetic background, followed by a deterioration of health [71]); and second - restoration of the volume of the incoming electromagnetic waves solar spectrum. Natural ilfüstration of the above can be considered as the situation with the vvinter-spring morbidity and efficiency improvement of the summer. Indicative data, obtained during the survey of the population of different regions of Ukraine [18, 19]. Let us consider in more detail the main groups of mentioned electromagnetic influences (I'able 2).
As you can see, natural capabilities that compensate electromagnetic waves of solar spectnim are limited and the only adequate alternative is polychromatic polarized (PILER) light. Accordingly, the deiice BIOPTRON as its generator represents an additional opportunity to align the electromagnetic balance.
The range of sun doses influence flucfüations in terrestrial coiiditions is very broad, and they vary depending on the different circumstances (Table 3). It is significant that an overdose of sun exposure mostly accompanied by an increased dose of its ?iltraviolet and infrared parts, and its lack reveals in a decrease of the visible portion of the solar spectrum. It should also be noted that even the small part of the sunliglit that reaches the Earth's surface in polarized form, under the influence of industrial dust or smog, is depolarized and loses biological effectiveness.
Main mechanisms and the concept of PILER-light therapy
From these data it follows that general indications for correctioii of föe electromagnetic imbalance can be called a disorder associated with electromagnetic lack, overload by "parasitic" electromagnetic waves and free radicals. BIOPTRON-PILER-light therapy method is the most appropriate to provide the most physiological way of electromagnetic harmony recovery at all levels of the organism - from molecular to systemic.
While the direct impact on the biological substrate of electromagnetic waves of the visible spectrum there
occurs a direct energy replenishment of the electroii oföits components and transition of electrons to higher levels, which increases the chemical activity of atoms.
Redistribution intermolecular energy leads to modification of the molecule, which defines a more pronounced stabilization of its structure. Restoration of tl'ie strucfüre portions of cell membraiies by electromagnetic reconfiguration of molecules increases the membrane potential and its ability to resist the action of free radicals. Especially effective action, PILER-light manifested in case of electromagnetic imbalance that defines the subsequent leveling therapeutic effect. Here reveals biophysical aspect of the PILER-light antioxidant effect.
This process prevents tlie progress of other, less favorable changes occurring under the influence of electromagnetic wave of other lengths (ultraviolet, infrared, microwave, etc.), manifested in the strengthening of intermolecular oscillatory processes, heating and breaking of intermolecular bonds.
Manifestations of the general mechanism of PILER-light action will not be the same depending on the regional properties of the perceiiring surface area of the skin. The process described above takes place in all cases of direct (local) impact. However, if in a zone of light application gets a biologically active (acupuncture) point, there turns on the mechanism of "lightweight" entering of biologically necessary electromagnetic energy range and its subsequent transport to customers located isi the electromagnetic "frame." Thus, there appears a possibility of systemic influence on organs distant from the application site. This principle is tl'ie basis for BIOPTRON color therapy technology as a painkiller and visceral system correcter.
PILER-light due to its polarization has better penetration ability compared to non-polarized electromagnetic waves. This opens ?ip another useful chain connected with direct influence on the cells and plasma of blood passing through the capillaries of the skin.
Restoring of their function ensures, on the one hand, strengthening of the strricture of erythrocyte membranes and extending the active life period of red lilood cells in the bloodstream, and on föe other hand - activation of leukocytes and lymphocytes function - immune proteins production, increase of pliagocytosis, etc. [65, 72]. It is typical, that at almost any light application capillary network is automatically covered within tlie illuminated area and, accordingly, the immune normalizing mechanism starts to work, which is extremely important for practical medicine.
Currently known mechanisms of polarized light action are actually aimed at slowing down the natural process (apoptosis) or induced (necrosis), destruction of cellular functions, i.e. breaking the process of cell death.
The PILER-light therapy concept, in modern sense, consists in combined application of local and systemic effects of polarized electromagnetic waves of
DESTROYING
(E) Cosmic rays
Abandant solar
A(,tivity
(' (3amma rays
8 X-rays
@ UV rays
(8» IR rays
0 MicrowaVeS (more than 1 mW/cm")
(E) LAZ E R-li g h t (high energy)
(' Ultrasound
Types of electromagnetic influences
DESTABILIZING
OTransporkation
* Electric locomotive, Metro
ii Tram3, trolleybuses
* Power Lines
* Flights
@ Domestic
* Microwaves
-1V
* Radio sets
* Cell Phones
ii Conditioners
* Aerowaterionizers, ozonizers
* Plastics
O In office
* Displays PC
* Electric engines
* Transformers
ii Ultrasound equipment
* Radars
* High-frequency generators
* Radio TV stations
@ Noise producers
* Traffic noise
* Concert noise
* Industrial noise
(' Molecular-nuclear
* Torsion fields
* Gravitation fields
@ Magnetic storm
' Solar
* Earkhly
Table 2
REGENERATIVE
@ PILER-light (polychromatic, 95 '/o of polarization, low-energy)
@Sunlight (polychromatic, up to 3 Yo of polarization)
@ LASER-light (monochromatic, polarized, low-energy)
@Mikrowaves (Nonpolarized, less than 1 mW/cm2)
@ LED-light (monochromatic, non polarized, low-energy)
Reasons for the solar electromagneticdisharmony
NATURAL
* Mountain conditions
* Recession of ozone layer
*Solar atmospheric magnetic storms
* Polar (summer) day
* Atmosphere polution
a:* Long dense cloudiness
a> Magnet atmosphere anomalies
'a Polar (winter) night
Table 3
ARTIFCIAL
OVEREXPOSURE
* Many hours of work in the sun
* Sun overdose
+ Overexposure to the sun/snow in the mountains
+ Solarium overdoze exposure
+ Electric welding
DEFICIENCY EXPOSURE
*.% Stay in low light premises
I.* Stay in screened rooms, transpork, marine and submarine vessels
*a Work in mines, workshops, basements, hyperbaric chambers
A. Distorted sunlight structure by glass, light filters
biologically necessary (solar) range, using specialized sensory receptor or sensory entrance gates, liquid-crystal conductors and all the connective framework for electromagnetic energy transport to regulatory system or areas, experiencing its deficit or imbalance.
In case of PILER-light therapy prescription, it is important to know the mechanisms of action of polarized light and clearly determine tlie feasibility of its aplication. It is helpful to understand the PILIE,R-light therapy-leading role in a complex antioxidant Zepter technology (simultaneous use). Enhancing of föe effect in this case is provided by ?midirectional (peroxide oxidation-reduction), coirection of various components of antioxidant balance [20]. The point of application and the level of biochemical or electromagnetic antioxidant protection, in eacli case, are not the same - from the cell membrane to the systemic organ that creates a multi-level aiid wider coverage for such electromagnetic disharmonies protection.
Achievementr and prospects of PILER-light therapy technologies
Staxt of the 3rd millennium for light therapy, as for physical therapy technique in a broad sense, is characterized by "warming" of 'classical" medicine attitude and successful searcli of cooperation wifö experts applying "non-traditional" approaches. This is due to accumulation of objective information about föe mechanisms of the physical factors action for specific medical purposes, the expansion of the deirices ' feafüres and transition to a new level of computer processing and evaluation of facts.New methodological possibilities defined reassessment of the existing provisions and allowed to provide greater depth of the facts analysis. The gulf reduced between "fundamental" and "applied" researches, which in fact, under the new conditioiis of the Ukrainian science existence, have grown finally together in a comprehensive system to obtain reliable scientific facts, introduce them into clinical disciplines
and rece timely feedback on the medico-social "order" for new research. In this sense, light therapy occured in a pole position. On the one hand, in due time, there appeared a new generation of ligl'it therapy equipment, sophisticated Bioptron device, on the oföer - thanks to open to independent research policy of Zepter Company, it has become real in Ukraine to do föeoretical and clinical researcli, with the ultimate aim to create better oppoitunities for healfö correction and improve quality of life. Contribution to the fast track of light therap)i technology development has made public understanding of the rapidly of negativ "parasitic" electromagnetic background growing, which increased its demand [12, 17, 25, 26, 41, 43, 64, 65, 74, 803.
The greater the accumulated knowledge of physical therapy techniq?ies, the more visible they are incomplete. Clinical needs and expectations of users require for Advanced Studies of increasing complexity aiid depth of analysis. Clarification of the PILER-light mechanisms of actioii has not changed its clinical efficiecy, but the list of diseases and premorbid disorders got a trend to decrease, which reflects improvement in föe q?iality of care. A rmmber of myths, ca?ised by primary enthusiasm and unexplaiiied effects, gradually disappear, it is replaced by a sober list of indications that distinguishes a professional approach. However, the technology remains to be designed for a wide user, preferably having BIOPTRON at his own home. The task of the researcher contimies to remain bidirectional - deeply investigate undisclosed facets of the teclinology and to provide speci'fic modes for practical application. Status of knowledge about the basic issues of solved and unsolved light therapy technologies, wliich appeared to date, are presented in Table 4.
Thus, at present, questions of legal and medical legalization of light aiid color föerapy can be considered as resolved. Tliere are defined the basic mechanisms of PILER-light action and a set of indications for applications.It is developed tlie first generation of therapeutic regimes and color therapeutic programs.
BIOPTRON: sofüed and unsolved questions
SETTLED SOLVED FOR DECISION
Full medical and legal authrlization of BIOPTRON devices
The main mechanisms of PILER-ligh action are defined
The basic therapeutic areas are described
Established the basic indications for treatment and correction
It created the first generation color therapy treatment and rehabilitation programs
Initial introduction of the population of the possibility of Bioptron light therapy
Table 4
Updating of the list of diseases for which light therapy is effective
Detailzation f physiological and pathophysiological mechanisms of Pilar-light action
Search for the new aspects of the therapeutic, restorative and preventive application of PILER-light
Extension of family BIOPTRON devices application
Implementation of color therapy programs and tcreation of their new modifications
Full coverage (each family) by light and color therapy technologies
In recent years, attention has been paid to a new nano filter containing fullerene (the fourth form of carbon state, molecular, C60) [81]. It is able at the nano level to change the properties of the light passing throrigh it. Accordiiigly, such light can acquire additional properties [82].
They arise due to tlie fact that the caföon atoms entering into the C60 molecule can influence the tra5ectory of the transmitted light quanta by its own electromagnetic oscillations, whicli obey the icosahedral symmetry of tl'ie shell. Rotating at speed of 1.8 x lOlo s-1, the spatial network of carbon atoms entering the Cbo molecule, in accordance with the Fiboiiacci distribution law (4)2 + $a2 = 3), additionally redistributes the light electromagnetic flux. Such a modification of the light flux was called '!iyperpolarization". When light passes tlirough a fullerene material 2 mm thick (106 layers of C60 molecules), there occur changes 1018 in the direction of the motioii of quanta. Taking into acco?int the rotation of föe C60 molecule, a new, more ordered spiral coiifiguration of their flow (Tesla toroids) is eventually created. The symmetry of the flux of quanta obtained in this way should create harmonizing possibilities for more efficient absorption of each of the passing q?ianta [82-84].
It was experimentally established [85, 86], that a 10-minute application to the inflammation locus or to E-36 acupuncture point of fullerene light caused in animals a significant reduction of pain. Analgesia was 43.5 and 38.5 %, respectively. All non-painful behavioral reactions increased their duration. Duration of sleep compared with tlie control increased twice (application of light to the locus of inflammation) and 3 times (application to acupuncture point E-36).
.:?;Ä'=,e
Fig. 6. Scheme of converting diffuse light into vertically linearly polarized and hyperpolarized [19, 83, 84]: 1 - scheme of oscillations of vectors oflight electromagnetic waves, 2 - Brewster polarizer of the BIOPTRON device.
Differences in the vector structure of the light fluxes are shown separately (circled).
Comparisoii of these data witli the results obtained for monochromatic polarized light ranges showed that they co?ild be attributed to the most effective group of analgesic light factors. Fullerene light, along with analgesic, have a powerful sedative effect, surpassing effects in comparison with all other ranges of polarized light. So, the new fact is föat polarized polychromatic light of the BIOPTRON device, which has passed through a nano photonic fullerene filter, acting onto the paiii or acupuncture point E-36, significantly reduces pain and l'ias a sedative effect.
Conclusion
Presented analytical material comprises a working concept of light therapy based on modern views of föe relationship between electromagnetic factors with a living organism. It is based on the use of acupuncture points for föe biologically necessary electromagnetic waves to enter the system (frame) of the cond?ictors and consideration the electromagnetic framework as a means of light range polarized electromagnetic waves transport. Their zones-recipient may be coiisidered orgaiis tliat endure electromagnetic imbalance due to the excess of biologically inadeq?iate radiation, suffering from free radicals' congestion (peroxidation) - neuro hormonal and immune regulatory systems of the organism to a greater or lesser extent related to biologically active periphery. Subseqrient stimulation or modification of functions of the recipient zones determines the achievements of useful therapeutic effect, combination of which with local reparative processes, derived from direct exposure, allows to achieve the clinical purpose. The results of targeted experimental sfüdies and cliiiical experience that gradually accumulate, will refine or change some of the positions that will give an impetus to tlie further improvement of the light therapy technology, and perhaps will give a q?ialitative leap.
The liglit therapy success now requires coordination of professionals' having experience in the field, systemic discussions, regular publication of the experimental results and clinical studies, significant efforts to extend information among managers and users, corresponding lecture activity.
BIOPTRON-light therapy is a new and promising directioii for a wide range of specialists, from representatives of theoretical medicine to clinicians and practitioners (beauticians, chiropractors, etc.). Studies in these iiew directions will always remain rewarding, as föe expansion of knowledge of concrete members and associates defines the achievement of a new quality of health medical support, föe pursuit of which is humane and honorable task of everyone.
The author will consider the goal reached in case of a significant appearance of interest to issues of electromagnetic eco}o(4y, BIOPTRON light therapy, and as a result, occupation by it a leading position in physical therapy.
Conelusions
1. The increase of the adverse electromagnetic background may be an additional cause for non-specific disease growth. The last can be explained by the presence of electromagnetic imbalance and environment-related free radical overloads.
2. Natural options to compensate electromagnetic wave solar spectrum lack is limited, adequate alternative is PILER-light.
3. We put forward the hypothesis of föe existence of the body's functional system of electromagnetic balance regulation.
4. Working light therapy concept is based on the possibility of xising acupuncture points, the biologically necessary electromagnetic waves, to enter conductors and consideration of this electromagnetic framework as a means of transport. Zones-recipients are named organs experiencing an electromagnetic imbalance due to excess of biologically inadequate radiation, overload by free radicals of neuro hormonal and immune regulatoiy systems. Subsequent stimulation or modification of functions of zoiies-recipients determines the achievement of useful therapeutic effect, combination of which with local reparative processes allow to acliieve clinical goals.
5. The modern approach to light föerapy is in combined (local and systemic) impact of electromagnetic waves of biologically necessary (light) range.
6. Settled, for the present time, can be considered legal and medical recognition of light color therapy, the basic mechanisms of PILER-light action, a list of indications, and the first generation of therapeutic regimes and color therapy programs.
7. Intensification of light therapy implementation technology is associated wifö the need to create new treatment programs and to develop color therapy analgesic technologies. We are faced with search and disclosure of PILER-light therapeutic action mechanisms in respect to the visceral systems, studies in biophysics, virology, veterinary medicine, crop and emergency medicine, development of a new generation of light therapy equiliment, as well as Zepter antioxidant technologies consolidation.
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