World Sleep 2025 Scientific Program

SCIENTIFIC PROGRAM

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Welcome to Singapore!

Dear Colleagues,

Welcome to World Sleep 2025 in Singapore! Thank you for attending the 18th edition of the World Sleep congress.

You are joining more than 3,000 researchers, clinicians, trainees, and other health professionals from over 75 countries for the largest World Sleep congress program yet. We hope this international exchange of perspectives and knowledge will strengthen your commitment to sleep health. Your attendance is vital to make World Sleep a special opportunity for the global sleep health community to connect and grow stronger together.

Thank you to the Asian Society of Sleep Medicine, our host society, for their invaluable contributions to the success of the program. I also sincerely thank the Singapore Tourism Bureau for their gracious support of World Sleep 2025. Singapore is an exceptional setting for such a congress, and I hope that you find some time to enjoy the city.

Find daily schedules and other practical congress information in the pages that follow. Note your must-see sessions and make plans to connect with colleagues. Enjoy your time in Singapore – and see you next in Montreal in 2027!

Sincerely,

Charles M. Morin, PhD Chair, Program Committee

2025 Program Committee

Chair

Charles M. Morin (Canada)

Maree Barnes (Australia)

Michael Chee (Singapore)

Peter Eastwood (Australia)

Raffaele Ferri (Italy)

Fang Han (China)

Seung Bong Hong (Republic of Korea)

Yuichi Inoue (Japan)

Gilles Lavigne (Canada)

Sutapa Mukherjee (Australia)

Allan O’Bryan (United States)

Thomas Penzel (Germany)

Dalva Poyares (Brazil)

Yun Kwok Wing (Hong Kong)

Phyllis C. Zee (United States)

2025 Program Overview

Congress Dates

September 5 – 10, 2025

Courses

Saturday, September 6 –

Sunday, September 7, 2025

Scientific Program

Monday, September 8 –

Wednesday, September 10, 2025

Venue & Location

Suntec Singapore Convention & Exhibition Centre

1 Raffles Blvd, Singapore

Scientific Program Topics

• Aging and developmental issues

• Basic research

• Chronobiology / Circadian disorders

• Dental / Surgery

• Dreaming

• Excessive daytime sleepiness / Hypersomnia

• Insomnia

• Movement disorders / RLS

• Narcolepsy

• Neurological disorders affecting sleep

• Parasomnias and REM

• Pediatrics

• Pharmacology

• Psychiatric disorders

• Sleep and cognition

• Sleep breathing disorders

• Sleep health

• Technology

• Women’s sleep health

Registration

Your World Sleep 2025 registration includes:

• All sessions over September 8 – 10

o Keynotes

o Symposia

o Lunch sessions

o Discussion groups and workshops

o Poster & oral abstracts

• Exhibit hall

• Opening ceremony & reception Ticket

Separate tickets are required for:

• ASSM 2025 Scientific Meeting

• Courses over September 6 and 7

• World Sleep Foundation Awards Reception

• Gala dinner

• 5k Fun Run / Walk

Visit the registration desk on Level 3 for information on latest availability of tickets.

Philips SleepStudio: Where Science Meets Practice

Philips Sleeposium: Frontiers of Sleep Sciences in 2025

LeadForward 2025: Empowering Conversations, Inspiring Action

World Sleep Congress 2025

5 – 10 September

At Philips, we are committed to what matters most: safe and effective solutions that advance Sleep and Respiratory Care. Join us as we participate in World Sleep Congress 2025 with the following activities: For

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Meeting Organizers

World Sleep Society

The mission of World Sleep Society is to convene the world of sleep medicine science, practice, and advocacy. World Sleep Society fosters a multidisciplinary and global sleep community to benefit its professional members and the health and wellness of people worldwide. The biennial World Sleep congress is organized to share the latest research findings, build international connections, and help develop the next generation of leaders in sleep.

Contact Information

World Sleep Society

3270 19th Street NW, Suite 109 Rochester, MN 55901 USA

+001-507-316-0084

info@worldsleepsociety.org

worldsleepsociety.org | worldsleepcongress.com

Have Questions?

Registration, Membership info@worldsleepsociety.org

Scientific Program

Angie Granum, Meeting Manager granum@worldsleepsociety.org

Exhibitor, Sponsor, Media

Tyler Ringstad, Communications Manager ringstad@worldsleepsociety.org

Asian Society of Sleep Medicine

The Asian Society of Sleep Medicine (ASSM) is the official host society for World Sleep 2025 in Singapore. Founded in 2015, the ASSM promotes all aspects of sleep medicine and research in Asia. The ASSM regularly holds scientific meetings to encourage international exchange and knowledge transfer in sleep medicine, advancing sleep health for all Asian populations.

ASSM is holding a scientific meeting over September 6 and 7 at World Sleep 2025. A separate registration is required. Please visit the registration area on Level 3 if you require a registration.

Thank you to the Singapore Tourism Board for their support of World Sleep 2025.

The goal of advancing sleep medicine through patient-centered innovation

For over two decades, Jazz Pharmaceuticals has been at the forefront of sleep medicine, dedicated to transforming the lives of people with complex sleep disorders such as narcolepsy and idiopathic hypersomnia.

Our commitment is rooted in understanding and addressing the unique, real-world challenges faced by the patients we serve.

Committees

Officers of World Sleep Society

The officers comprise the Executive Committee of the World Sleep Society.

President: Raffaele Ferri (Italy)

President-Elect: Thomas Penzel (Germany)

Secretary: Lourdes DelRosso (United States)

Treasurer: Maree Barnes (Australia)

Past President: Phyllis C. Zee (United States)

Members at Large

Africa: Morenikeji Komolafe (Nigeria)

Asia or Australia: Amy Reynolds (Australia)

Europe: Karen Spruyt (France)

North America: Ofer Jacobowitz (United States)

Central or South America: Edilson Zancanella (Brazil)

Society Representatives

Society representatives are chosen through a separate but concurrent election in which all Associate Society Members of World Sleep Society vote and elect five societies among them to seat one representative each on the Governing Council.

Alexander Abreu (United States)

American Academy of Sleep Medicine (AASM)

Sutapa Mukherjee (Australia)

Australasian Sleep Association (ASA)

Erna Sif Arnardóttir (Iceland)

European Sleep Research Society (ESRS)

Paul Gringras (United Kingdom)

International Pediatric Sleep Association (IPSA)

Megan Petrov (United States)

Sleep Research Society (SRS)

Scientific Selection for the Congress

The Program Committee of each World Sleep congress is created following the World Sleep Society bylaws of committee formation, including six members of World Sleep Society and three members of the local host society. Topics are determined and proposal reviews organized by the Program Committee using established policies and procedures to mitigate bias and ensure scientific excellence.

World Sleep 2025 Program Committee

Chair Charles Morin (Canada)

Maree Barnes (Australia)

Michael Chee (Singapore)

Peter Eastwood (Australia)

Raffaele Ferri (Italy)

Fang Han (China)

Seung Bong Hong (Republic of Korea)

Yuichi Inoue (Japan)

Gilles Lavigne (Canada)

Sutapa Mukherjee (Australia)

Allan O’Bryan (United States)

Thomas Penzel (Germany)

Dalva Poyares (Brazil)

Yun Kwok Wing (Hong Kong)

Phyllis C. Zee (United States)

World Sleep 2025 International Scientific Committee

The International Scientific Committee is essential to the development of a scientifically and internationally balanced program. The primary responsibility of the International Scientific Committee is to review and score oral and poster abstract submissions.

Mohammed A. Al-Abri (Oman)

Diego Alvarez-Estevez (Spain)

Tarun Amalnerkar (Malaysia)

Paula Araujo (Brazil)

Chun Ting Au (Canada)

Najib Ayas (Canada)

Lucie Barateau (France)

Célyne Bastien (Canada)

Lais F. Berro (United States)

Suzanne Bertisch (United States)

Saadoun Bin-Hasan (Kuwait)

Bjørn Bjorvatn (Norway)

Perran Boran (Türkiye)

Antje Büttner-Teleagă (Germany)

José Carlos Carneiro (Portugal)

Mary Carskadon (United States)

Stephen Carstensen (United States)

Matteo Cesari (Austria)

Joey Wing Yan Chan (Hong Kong)

Kate Ching Ching Chan (Hong Kong)

Rachel Ngan Yin Chan (Hong Kong)

Ning-Hung Chen (Taiwan)

Naricha Chirakalwasan (Thailand)

Frances Chung (Canada)

Seockhoon Chung (South Korea)

Nancy Collop (United States)

Kimberly Cote (Canada)

Naima Covassin (United States)

Antonio Culebras (United States)

Thanh Dang-Vu (Canada)

Yves Dauvilliers (France)

Tom Deboer (Netherlands)

Philip de Chazal (Australia)

Joseph De Koninck (Canada)

Helen Driver (Canada)

Jeanne Duffy (United States)

Sy Duong-Quy (Vietnam)

Alan L. Eckeli (Brazil)

Bradley Edwards (Australia)

Leila Emami (Iran)

Geraldo Lorenzi Filho (Brazil)

John Fleetham (Canada)

Xuemei Gao (China)

Arturo Garay (Argentina)

Diego Garcia Borreguero (Spain)

Symielle Gaston (United States)

Pedro Genta (Brazil)

Cathy Goldstein (United States)

Joshua J. Gooley (Singapore)

Michael Grandner (United States)

Reut Gruber (Canada)

Helena Hachul (Brazil)

Wendy Hall (Canada)

Devon Hansen (United States)

Anna Heidbreder (Austria)

Max Hirshkowitz (United States)

Seung-Chul Hong (Korea)

Rosemary Horne (Australia)

Yu-Shu Huang (Taiwan)

Abubaker Ibrahim (Austria)

Osman Ipsiroglu (Canada)

Chandra Jackson (United States)

Melinda Jackson (Australia)

Eun Yeon Joo (Korea)

Amy Jordan (Australia)

Hiroshi Kadotani (Japan)

Michal Kahn (Israel)

Marta Kaminska (Canada)

Takashi Kanbayashi (Japan)

Takafumi Kato (Japan)

Amrit Kaur (India)

Hakan Cudi Kaynak (Türkiye)

Sharon Keenan (United States)

Thomas Kilduff (United States)

Keun Tae Kim (South Korea)

Lenise Jihe Kim (Brazil)

Minjee Kim (United States)

Jun Kohyama (Japan)

Suresh Kotagal (United States)

Vijaya Krishnan Paramasivan (India)

Clete Kushida (United States)

World Sleep 2025 International Scientific Committee

Michel Lecendreux (France)

Glenn Legault (Canada)

Leong-Chai Leow (Singapore)

Albert Martin Li (Hong Kong)

Diane C. Lim (United States)

Chia Jou Lin (Taiwan)

Cheng-Hui Lin (Taiwan)

Michelangelo Maestri (Italy)

Atul Malhotra (United States)

Hrudananda Mallick (India)

Jessica Manousakis (Australia)

Marie Marklund (Sweden)

Stijn Massar (Singapore)

Nigel Mcardle (Australia)

Walter McNicholas (Ireland)

Ludovico Messineo (United States)

Maria Paola Mogavero (Italy)

Gary Garcia Molina (United States)

Gustavo Antonio Moreira (Brazil)

Lucia Muntean (Germany)

Brian Murray (Canada)

Jini Naidoo (United States)

Arezu Najafi (Iran)

Indra Narang (Canada)

Alister Neill (New Zealand)

Sona Nevsimalova (Czech Republic)

Sara Op de Beeck (Belgium)

Teresa Paiva (Portugal)

Laura Palagini (Italy)

John Peever (Canada)

Jean-Louis Pépin (France)

Federica Provini (Italy)

Monica Puligheddu (Italy)

Winfried Randerath (Germany)

Graham Reid (Canada)

Cáitia Reis (Portugal)

Imthiaz Refayee (India)

Amy Reynolds (Australia)

Dieter Riemann (Germany)

Gabrielle Rigney (Australia)

Leon Rosenthal (United States)

Taeko Sakuma (Japan)

Scott Sands (United States)

Carlos Schenck (United States)

Kathy Sexton-Radek (United States)

Amir Sharafkhaneh (United States)

Alessandro Silvani (Italy)

Robert Skomro (Canada)

Tracey Sletten (Australia)

Kai Spiegelhalder (Germany)

Sapna Erat Sreedharan (India)

Ambra Stefani (Austria)

Marie-Pierre St-Onge (United States)

Sooyeon “Aly” Suh (South Korea)

Jagdish Chander Suri (India)

Mehdi Tafti (Switzerland)

Yuta Takano (Japan)

Xiao Tan (China)

Megan Thomas (Canada)

Robert Thomas (United States)

Claudia Trenkwalder (Germany)

Andrew Vakulin (Australia)

Eus Van Someren (Netherlands)

Johan Verbraecken (Belgium)

Punam Verma (India)

Guanghai Wang (China)

Wenjing Wang (China)

Shelly Weiss (Canada)

Adrian Willoughby (Singapore)

John Winkelman (United States)

Liyue Xu (China)

Mimi Yow (Singapore)

Edilson Zancanella (Brazil)

Bingqian Zhu (China)

Marco Zucconi (Italy)

General Information

Venue & Location

Suntec Singapore Convention & Exhibition Centre 1 Raffles Blvd, Singapore

Continuing Medical Education (CME)

The number of CME credits available at World Sleep 2025 is to be determined. Attendees are responsible for purchasing the $25 CME fee, recording their activities, and submitting them to World Sleep Society for processing..

Badge Identification

All congress participants and guests must wear a World Sleep 2025 congress badge. Badges allow entrance to the scientific sessions and access to the convention center. Your cooperation with this policy is appreciated. Recycle your badge holder after the congress by dropping it off at the registration desk. Replacement badges can be obtained at the registration desk for a fee.

Registration Desk | Level 3

Registration materials (bags, final programs, tickets, etc.) will be provided at the registration desk located on Level 3.. Tickets are required for entry to the gala dinner and to pre-congress courses on Saturday and Sunday. Tickets can be purchased online or at the registration desk.

Registration Desk Hours

Visit the registration desk on Level 3 for any questions about World Sleep 2025.

Friday, September 5 4:00pm – 8:00pm

Saturday, September 6 7:00am – 6:00pm

Sunday, September 7 7:00am – 6:00pm

Monday, September 8 7:00am – 6:00pm

Tuesday, September 9 7:00am – 6:00pm Wednesday, September 10 7:00am – 4:00pm

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app! SCAN TO

General Information

Speaker Ready Room | Level 3, Room 323

Speakers can upload and preview their presentations in room 323, which is near the registration area. Speakers are required to upload their presentations at least 12 hours before their scheduled session begins. A technician will be available to assist as needed.

Speaker Ready Room Hours

Saturday, September 6

7:00am – 5:00pm

Sunday, September 7

7:00am – 5:00pm

Monday, September 8

7:00am – 5:00pm

Tuesday, September 9

7:00am – 5:00pm

Wednesday, September 10

7:00am – 5:00pm

Exhibition Hours | Level 4, Hall 405

Monday, September 8

8:30am – 3:30pm

Tuesday, September 9

8:30am – 3:30pm

Wednesday, September 10

8:30am – 3:30pm

Press Room

Members of the press and media are welcome to use the speaker ready room to work.

Electronic Devices

Please turn all electronic devices (phones, pagers, etc.) to silent mode during presentations. As a courtesy to the presenters and audience, phone calls should be taken outside of the scientific sessions.

Recording Device Policy

No recording devices, audio or visual, may be used during CME activities. Duplication, distribution, or excerpting of this program without the express written permission of World Sleep Society is strictly prohibited. All of the proceedings of this program, including the presentation of scientific papers, are intended for limited publication only, and all property rights in the material presented, including common-law copyright, are expressly reserved by the Faculty, World Sleep Society, and/or CME provider. No statement of presentation made is to be regarded as dedicated to the public domain. Any sound reproduction, transcript, or other use of the material presented at this CME activity without the permission of World Sleep Society and CME provider is prohibited to the full extent of common-law copyright in such material.

Cameras and recording devices are not allowed to be used in the scientific meeting rooms at any time. Violation of this rule could result in removal from the congress along with the confiscation of the film and/ or recording device.

Seating

Scientific sessions are filled on a first-come, firstserved basis. World Sleep Society and the Program Committee reviewed the scientific sessions to anticipate demand and match the room size with expected seating. Occasionally, a presentation will have higher demand than expected. We encourage delegates to arrive early for the best possible seating.

Floor Plans

Level 3

What’s on Level 3?

• Registration • Speaker Ready Room • Symposia • Oral Abstracts

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

Floor Plans

Level 4

What’s on Level 4?

• Keynote Presentations • Symposia • Poster Hall • Exhibit Hall

Find the list of all exhibitors and their booth numbers on page 181. All exhibitor information is also available in the official World Sleep 2025 app. Exhibition begins at 8:30am on Monday, Tuesday, and Wednesday.

Networking and Social Events

Opening Ceremony

Sunday, September 7

6:30pm – 8:15pm

Level 4, Hall 406 C

Suntec Singapore Convention & Exhibition Centre

Brief opening remarks will be followed by cultural entertainment – including a Lion Dance – and a reception with drinks. All registered attendees are welcome; no ticket is required.

World Sleep Foundation Award Reception

Sunday, September 7

8:15pm – 9:45pm

Level 3, Room 324

Suntec Singapore Convention & Exhibition Centre

Join us to celebrate excellence in sleep research, education, and advocacy at the World Sleep Foundation Award Reception. Awards will be presented along with food and drink for attendees.

Gala Dinner

Tuesday, September 9

7:00pm – 11:00pm

Gardens by the Bay 18 Marina Gardens Drive, Singapore 018953

Enjoy an unforgettable evening among the iconic Supertrees and lush greenery of Singapore’s Gardens by the Bay. Tickets are required and pre-sales have sold out. Please visit the registration area on Level 3 for the latest ticket availability.

Networking and Social Events

New for World Sleep 2025

5K Fun Run / Walk

Poster Hall Sessions

Sunday, September 7 | 5:00pm – 6:00pm Monday, September 8 | 6:30pm – 7:30pm Tuesday, September 9 | 4:45pm – 5:45pm

Level 4, Hall 405

Browse the posters, meet presenters, ask questions, and explore the latest sleep research in a more open and discussion-based environment.

Tuesday, September 9

6:00am – 7:45am

Starting Point: DBS Foundation

Esplanade Outdoor Theatre

Start your day with movement and breathtaking views of Singapore’s Marina Bay. Run or walk past waterfront landmarks – including the Merlion and Marina Bay Sands – as the sun rises on another exciting congress day.

All event proceeds support the Christian Guilleminault (CG) Young Investigator Fund, which distributes awards to early-career sleep researchers.

Suntec Singapore Convention & Exhibition Centre Wednesday, September 10 6:30pm – 7:10pm

Closing Ceremony

Level 3, Room Nicoll 1

Suntec Singapore Convention & Exhibition Centre

Hear closing remarks from the Program Committee, learn the results of the World Sleep Society election, and get a preview of World Sleep 2027 in Montreal. Light refreshments will be served.

Awards

New Investigator Awards for Oral and Poster Abstract Presentations

New Investigator Award recipients are selected among eligible presenters of oral and poster abstracts at World Sleep 2025. Find the details of the award-winning oral abstracts below, and attend the presentations to show support for the next generation of leaders in sleep research. Award-winning poster presenters will be announced and recognized during each poster hall session. Browse the hall to meet them all!

TUESDAY September 9

Christianne Martins Correa da Silva (Brazil)

Precision medicine approach in Brazilian patients with primary hypersomnias using hypocretin and high-resolution HLA sequencing: insights from a multiethnic population

Session: O-17 starting at 9:00am on Tuesday in Room 327

Annapoorna Ramasubramanya (United States)

Investigating differential rhythmicity in circadian biomarkers using skin perspiration wearables

Session: O-19 starting at 9:00am on Tuesday in Room 329

Qiu-Ye Lan (China)

Association of Outdoor Artificial Light at Night with Sleep Duration and Social Jetlag Among Preschool-aged Children

Session: O-19 starting at 9:00am on Tuesday in Room 329

Yi Hui Ou (Singapore)

Mandibular advancement device versus CPAP on cardiovascular health and quality of life in OSA ─ a pre-specified 12 months follow up of outcome

Session: O-19 starting at 9:00am on Tuesday in Room 329

Shi Tang (Hong Kong, SAR of China)

Distinct gut microbial, brain gene expression and clinical progression profiles in REM sleep behavior disorder biotypes

Session: O-19 starting at 9:00am on Tuesday in Room 329

Irina Filchenko (Switzerland)

REM-sleep saw-tooth waves: cortical topography and associations with cognition

Session: O-19 starting at 9:00am on Tuesday in Room 329

Benjamin K Tong (Australia)

A Pilot Study of Personalized Obstructive Sleep Apnea Therapy in Patients with Acute Coronary Syndrome

Session: O-19 starting at 9:00am on Tuesday in Room 329

Suyi Xie (Hong Kong, SAR of China)

Associations Between Sleep Health and Gut Microbiota: A Metagenomic Analysis in a Community-Based Sample in Hong Kong

Session: O-22 starting at 10:45am on Tuesday in Room 328

Mohammadreza Hajipour (United States)

Electroencephalographic response to respiratory events is associated with all-cause mortality in obstructive sleep apnea

Session: O-23 starting at 10:45am on Tuesday in Room 329

Beatrice Orso (Italy)

[18F]FDG-PET as staging biomarker in the prodromal to overt neuronal alpha-synucleinopathy continuum

Session: O-25 starting at 3:15pm on Tuesday in Room 327

Ningning Li (Hong Kong, SAR of China)

Progression of prodromal markers of alpha-synucleinopathy neurodegeneration in the first-degree relatives of patients with REM sleep behavior disorder: a 7-year prospective study

Session: O-25 starting at 3:15pm on Tuesday in Room 329

Samantha Mombelli (Canada)

Altered sleep spindle morphology in idiopathic hypersomnia

Session: O-27 starting at 3:15pm on Tuesday in Room 329

Simone Bruno (United States)

Optimizing timing and dose of melatonin administration: a randomized, double-blind controlled trial in healthy adults

Session: O-27 starting at 3:15pm on Tuesday in Room 329

WEDNESDAY September 10

Rachel Ngan Yin Chan (Hong Kong)

Efficacy of a stepped care approach to deliver cognitive behavioural therapy for insomnia in the community: A pragmatic stepped-wedge cluster randomized controlled trial

Session: O-31 starting at 9:00am on Wednesday in Room 329

Valeria Mammarella (Italy)

Pathophysiological subtypes of paediatric insomnia based on familiar and clinical features

Session: O37 starting at 9:00am on Wednesday in Room 330

Chris Xie Chen (Hong Kong, SAR of China)

Correlates between sleep architecture and sleep reactivity to stress in the context of cumulative adversities: Is REM sleep continuity a potential protective factor for sleep reactivity?

Session: O-37 starting at 9:00am on Wednesday in Room 330

Shumpei Date (Japan)

Enhanced Phase-Amplitude Coupling Prior to Dream-Enactment Behaviors in isolated REM Sleep Behavior Disorder: A VideoPolysomnography Study

Session: O-32 starting at 10:45am on Wednesday in Room 327

Yasmin Potts (Australia)

Locus coeruleus inhibition in tau transgenic mice to treat neuropsychiatric and sleep disturbances in Alzheimer’s disease

Session: O-34 starting at 10:45am on Wednesday in Room 329

Awards

Christian Guilleminault Young Investigator Award

The Christian Guilleminault Young Investigator Awards are presented to encourage young investigators in the field of sleep, especially in developing portions of the world, to advance sleep medicine and research worldwide. Up to 2 awards of $1,000 will be offered to qualifying individuals.

2025 Christian Guilleminault Young Investigator Award Recipients

Huijie Yi (China)

The Effect of Telemedicine-Based CPAP Management on 24Hour Ambulatory Blood Pressure in Patients with Obstructive Sleep Apnea: A Randomized, Controlled, Non-Inferiority Trial Session: O-05 starting at 10:45am on Monday in Room 327

Ming Yang (China)

Inflammatory Biomarkers and Symptom Severity: The Role of Cytokines in Paediatric OSA Session: O-29 starting at 9:00am on Wednesday in Room 327

Elsevier Awards

Elsevier has established two scientific awards for new basic and clinical sleep specialists in honor of Christian Guilleminault and Elio Lugaresi. Two awards of $1,000 will be presented at World Sleep 2025.

2025 Young Investigator Award Recipients

Elio Lugaresi Award For Sleep Medicine

Ramkumar Sugumaran (India)

Melatonin on sleep in Parkinson’s disease: A randomized double blind placebo controlled trial

Christian Guilleminault Award for Sleep Research

Zahra Aghelan (Iran)

Serum levels of 1,3-β-D-glucan is correlated with NLRP3 inflammasome activation and insomnia severity in people with chronic insomnia disorder

Elsevier Awards Committee Chair — Antonio Culebras, MD (United States)

Elsevier Awards Committtee Members — Melissa Lipford, MD (United States); Elena Majano, MD (El Salvador); Liborio Parrino, MD (Italy); Federica Provini, MD (Italy); Bradley Vaughn, MD (United States)

Wayne Hening Young Investigator Awards

Wayne Hening Young Investigator Awards are presented to young investigators in the RLS/PLMS field. Up to five awards of $1,000 will be offered to qualifying individuals.

2025 Wayne Hening Young Investigator Award Recipients

Yanyan Hou (China)

Clinical Characteristics, Polysomnography, and Iron Metabolism in Restless Legs Syndrome Patients with Obstructive Sleep Apnea: A Comparative and Cluster Analysis Study Session: O-06 starting at 10:45am on Monday in Room 328

Katie L.J. Cederberg (United States)

Chronic Health Risk in Restless Legs Syndrome and its Association with Exercise

Session: Poster #309 in poster abstract group 2 starting at 6:30pm on Monday

Distinguished Service Awards

The Distinguished Service Awards recognize outstanding contributions to the world sleep community. Awards will be presented during the World Sleep Foundation Reception at 8:15pm on Sunday, September 7 in Room 324. Tickets are required for attendance.

Thank you to the recipients of this year’s Distinguished Service Awards!

• Maree Barnes (Australia)

• Judith Owens (United States)

• Jean-Charles Schwartz (France)

• Phyllis C. Zee (United States)

Keynote Speakers

Monday, September 8

8:00am – 8:45am

Hall 406 C

Thomas Penzel, PhD (Germany)

K-01 Innovations in sleep technology: Advancing diagnosis and treatment of sleep disorders

Hall 406 D

Russell Foster, PhD (United Kingdom)

K-02 Light, circadian rhythms and sleep: Fundamental mechanisms to new therapeutics

Tuesday, September 9 2:15pm – 3:00pm

Hall 406 C

Tiina Paunio, MD, PhD (Finland)

K-03 Sleep and development: Exploring the impact of sleep on mental health in children

Hall 406 D

Hiroki R. Ueda, MD, PhD (Japan)

K-04 Towards human systems biology of sleep/wake cycles: The role of calcium and phosphorylation in sleep

8:00am – 8:45am 2:15pm – 3:00pm

Hall 406 C

Lauren Hale, PhD (United States)

K-05 Social determinants and sleep health equity

Hall 406 D

Bei Bei, PhD (Australia)

K-06 Behavioral sleep interventions in women across the lifespan

Hall 406 C

Mary Ip, MBBS(HK), MD(HK) (Hong Kong)

K-07 Cardiometabolic consequences of obstructive sleep apnea: Are we making progress?

Hall 406 D

Célyne Bastien, PhD (Canada)

K-08 Sleep misperception: A waking perspective

Keynote Speakers

Wednesday, September 10

8:00am – 8:45am 2:15pm – 3:00pm

Hall 406 C

Takafumi Kato, DDS, PhD (Japan)

K-09 Advances in dental sleep medicine: Understanding the pathophysiology of sleep bruxism and co-existing sleep disorders

Hall 406 D

Ronald Postuma, MD (Canada)

K-10 REM sleep behavior disorder: Gateway to early diagnosis and therapy in synucleinopathies

Hall 406 C

Björn Rasch, Dr. rer. nat (Switzerland)

K-11 Sleep and memory: Current state of research and future needs

Hall 406 D

Joshua Gooley, PhD (Singapore)

K-12 The hard facts supporting later learning start times

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

SCAN TO DOWNLOAD THE WORLD SLEEP 2025 APP! Supported by

Meet Our Associate Society Members

Global

• International Pediatric Sleep Association

• International RLS Study Group

• International Surgical Sleep Society

• World Dentofacial Sleep Society

Region of the Americas

• American Academy of Sleep Medicine

• Brazilian Sleep Academy

• Canadian Sleep Society

• Asociación Latinoamericana de sueño

• Guatemalan Association of Sleep Medicine

• Peruvian Association of Sleep Medicine

• Sleep Research Society

• Society of Behavioral Sleep Medicine

• Venezuelan Academy of Sleep Medicine

South-East Asian Region

• Asian Society of Sleep Medicine

• Indian Association of Surgeons for Sleep Apnoea

• Indian Society for Sleep Research

• Indonesian Society of Sleep Medicine

• Sleep Society of Thailand

• South East Asian Academy of Sleep Medicine

Eastern Mediterranean Region

• Iranian Sleep Medicine Society

• Moroccan Society of Sleep and Vigilance

• Sleep Medicine Society of Kuwait

African Region

• Nigerian Sleep Society

• South African Society for Sleep and Health

Western Pacific Region

• Asian Sleep Research Society

• Australasian Sleep Association

• Australia and New Zealand Sleep Science Association (ANZSSA)

• Chinese Sleep Research Society

• Hong Kong Society of Sleep Medicine

• Integrated Sleep Medicine Society Japan

• Japanese Society of Sleep Research

• Philippine Society of Sleep Medicine

• Singapore Sleep Society

• Taiwan Society of Sleep Medicine

• Vietnam Society of Sleep Medicine

European Region

• Austrian Sleep Research Association

• British Sleep Society

• Bulgarian Association of Obstructive Sleep Apnea & Snoring

• Bulgarian Society of Somnology

• Czech Sleep Research and Sleep Medicine Society

• European RLS Study Group

• European Sleep Foundation

• European Sleep Research Society

• Finnish Sleep Research Society

• French Society for Sleep Research and Sleep Medicine

• Georgian Sleep Research and Sleep Medicine Society

• German Sleep Society

• Israel Sleep Research Society

• Portuguese Sleep Association

• Romanian Association for Pediatric Sleep Disorders

• Russian Society of Somnologists

• Serbian Sleep Society

• Turkish Sleep Medicine Society

Visit the Associate Society Pavilion in the Exhibit Hall at Space #240

World Sleep Society is proud to count over 50 sleep societies as Associate Society Members. Ten Associate Societies are joining us in person in the exhibit hall for World Sleep 2025. Visit them at space #240 to learn about their activities and make connections!

Exhibit Hall | Level 4, Hall 405

• Asian Society of Sleep Medicine

• Australia and New Zealand Sleep Science Association

• Australasian Sleep Association

• European Sleep Research Society

• Indian Association of Surgeons for Sleep Aponea *

• Integrated Sleep Medicine Society Japan

• International Surgical Sleep Society

• Iranian Sleep Medicine Society *

• Nigerian Sleep Society *

• Sleep Society of Thailand *

• South East Asian Association of Sleep Medicine

• Taiwan Sleep Society

• Venezuelan Academy of Sleep Medicine

• World Dentofacial Sleep Society

* Find display information related to this sleep society inside the exhibit hall near the entrances.

Associate Society Pavilion Space #240

Event Invitation

You’re Invited!

World Sleep Congress 2025

Suntec Singapore Convention & Exhibition Centre

Philips Sleeposium

Frontiers of Sleep Sciences in 2025

Join us for an exclusive clinical lunch symposium exploring the landscape of sleep medicine.

Collaboratively Shaping the Future of Sleep Medicine: Emerging Trends That Will Affect Us All

• AI in Sleep Medicine: Navigating Innovation and Implementation Challenges

• Personalization and Customization of Sleep Therapy

Speakers:

Moderator:

Dr. Teo lo Lee-Chiong (USA)

Dr. Ahmed BaHamman

9 September | 12:45pm – 01:45pm Regular Symposium Room, Hall 406D

Lunch will be provided.

*Disclaimer: Program details, including agenda and speakers, are subject to change without prior notice.

World Sleep Lunch Symposium

Tuesday, September 9th | 12:45 - 1:45 | Room 309

Precision Breathing: Advancing Sleep Apnea Phenotyping Through Accurate Flow Measurement

Join leading experts as they explore how precise airflow advances

OSA phenotyping, including ventilatory burden and OSA endotyping, to support more personalized care.

Chairs:

Prof. Han Fang, Peking University People’s Hospital

Prof. Liang Wen-Hang, China Medical University Hospita

Speakers and Titles:

Jón Skírnir Ágústsson, Ph.D., Nox Medical

Wan-Ju Cheng, MD, Ph.D., China Medical University Hospital

Scott Sands, Ph.D., Harvard University

The International Pediatric Sleep Association (IPSA) is pleased to announce the next edition of its biennial meeting!

Keynotes

Barbara Galland, PhD (New Zealand)

Unravelling the digital impact: Screens and sleep

Thomas Penzel, PhD (Germany)

Non obtrusive sleep recording and new analysis in pediatric sleep medicine

Global Perspectives in Narcolepsy Learning From Each Other

SUNTEC SINGAPORE CONVENTION & EXHIBITION CENTRE

1 RAFFLES BLVD, SINGAPORE | ROOM:

CHAIR

Yuichi Inoue, MD, PhD Professor Department of Somnology Tokyo Medical University Tokyo, Japan

SPEAKERS

Lucie Barateau, MD, PhD Associate Professor of Physiology Sleep-Wake Disorders Unit

Gui De Chauliac Hospital National Reference Centre for Narcolepsy Institute for Neurosciences of Montpellier University of Montpellier INSERM Montpellier, France

Anne Marie Morse, DO, FAASM Clinical Associate Professor Director, Child Neurology Director, Pediatric Sleep Medicine Program Director, Child Neurology Residency Geisinger Commonwealth School of Medicine Geisinger Medical Center Janet Weis Children’s Hospital Danville, Pennsylvania, United States

Thomas E. Scammell, MD Professor of Neurology Division of Sleep Medicine Harvard Medical School Boston, Massachusetts, United States

For more information and to register, visit: www.medscape.org/symposium/global-narcolepsy

September 8, 2025 12:45–13:45 SGT Room: 303

Welcome and introduction

Menopause and sleep: why it matters, how it happens

Measuring sleep in menopause: moving from the lab to the real world

Dual neurokinin-targeted therapy and beyond: mechanisms and guidelines

Panel discussion and Q&A

Closing remarks and key takeaways

PP-LNK-ALL-0017-1

Fiona Baker Director of Center for Health Sciences and Human Sleep Research Program, USA

Professor

IRCCS

IT

SleepMultiMedia

ACCESSIBLE SLEEP MEDICINE TRAINING AROUND THE WORLD

About

World Sleep Academy (WSA) is an online, year-long program in basic sleep medicine. The WSA offers accessible sleep medicine training to health professionals, helping to advance sleep health worldwide.

Tier Structure of WSA

World Sleep Academy is organized into three tiers. The tiers progress from introductory content in sleep science and medicine to advanced practice.

2026 Schedule

Tier 1

January–March

Sleep science and patient evaluation

Tier 2

April–August

Sleep disorders

Tier 3

September–December

Advanced courses in pediatric sleep and insomnia

Thank You to the 2024-25 World Sleep Academy Faculty

In appreciation for their dedicated work in curriculum development, assessment, and student engagement, the World Sleep Society is proud to acknowledge its faculty members. The Academy is only possible through their dedication.

Anna Wani (United States)

Anne Marie Morse (United States)

Ari Manuel (United Kingdom)

Arezu Najafi (Iran)

Aroonwan Preutthipan (Thailand)

Bingqian Zhu (China)

Catherine McCall (United States)

Elizaveta Solomonova (Canada)

Fan Jiang (China)

Federica Provini (Italy)

Golfam Javanoskooei (United States)

Harald Hrubos-Strøm (Norway)

Ignacio Tapia (United States)

Jun Au (Canada)

Jeremy Gutierrez (United States)

Jennifer Reed (United States)

Joanna Wrede (United States)

Jodie Mitchell (Australia)

Judith Owens (United States)

Julio Fernandez-Mendoza (United States)

Karen Spruyt (France)

Leila Emami (Iran)

Lourdes DelRosso (United States)

Mary Tablizo (United States)

Mayank Vats (India)

Melisa Moore (United States)

Morenikeji Komolafe (Nigeria)

Montida Veeravigrom (United States)

Oluwatosin Olorunmoteni (Nigeria)

Pam Douglas (Australia)

Perran Boran (Türkiye)

Ravindra Chandrashekhar (United States)

Robert Thomas (United States)

Romy Hoque (United States)

Ruby Joseph K (India)

Sarah Blunden (Australia)

Sheryl Cogdell (United States)

Shelley Zak (United States)

Sofia Konstantinopolou (United Arab Emirates)

Tiago Vasconcelos (Brazil)

Zhifei Xu (China)

Managing insomnia disorder

in patients with neurological and psychiatric comorbidities

Tuesday, 9 September | 12:45–14:15 Level 3, Nicoll 1

Chair: David Neubauer, United States Co-Chair: Lu Lin, China

12:45-13:05 The impact of insomnia disorder for patients

David Neubauer, United States

13:05-13:25 New clinical data on daridorexant for managing insomnia disorder

13:25-13:45

Atul Khullar, Canada

Clinical experience managing insomnia disorder in patients with psychiatric comorbidities

Laura Palagini, Italy

13:45-14:05 Clinical experience managing insomnia disorder in patients with neurological comorbidities

Claudio Liguori, Italy

14:05-14:15 Panel discussion and Q&A

Satellite Symposium at the 18th World Sleep Society Congress. Supported by Idorsia Pharmaceuticals Ltd.

Monday, September 8

12:45pm-1:45pm Room #326

Featured Speakers: Danny J. Eckert, PhD (Australia); Olivier M. Vanderveken, MD, PhD (Belgium); and Edward T. Sall, MD, DDS, MBA (USA)

Sunday, September 7

6:30pm – 8:15pm

Level 4, Hall 406 C

Opening Remarks | Welcome to Singapore Program Overview | Entertainment Reception

Reception to follow on Level 3 in rooms Nicoll 1 – 3. All registered attendees are welcome.

Supported by

ABOUT THE PROGRAM

The International Sleep Research Training Program (ISRTP) is a mentorship program that pairs early and mid-career researchers with world class leaders in their fields for one year of learning, collaboration, and connection with the global sleep community. ISRTP mentors represent many of the world’s leading sleep and circadian research institutions.

TOPICS COVERED WITHIN THE MENTORSHIP

• Research study development, implementation, and replication

• Clinical exposure to management of sleep disorders

• Scientific communication skills, including presenting and publishing

• Obtaining and managing research funds

• Career development and sleep clinic entrepreneurship

WONDERING IF ISRTP IS THE RIGHT FIT FOR YOU?

ISRTP will start its seventh year in July 2027. Contact Mike Mutschelknaus at mike@worldsleepsociety.org for more information and to find out if the ISRTP is right for you. This educational initiative is supported by:

A leader in orexin neurobiology research

Alkermes is honored to share the following oral scientific presentations at World Sleep 2025

Session: O-09: Targeting the orexin pathway: Emerging pharmacotherapies for narcolepsy type 1

Date: September 8, 2025 Time: 3:15-3:54pm Room: 327

Presentation Title

Vibrance-1: A Randomized Phase 2 Study Evaluating Safety and Efficacy of the Orexin 2 Receptor Agonist Alixorexton (ALKS 2680) in Patients with Narcolepsy Type 1

Improvement in the Severity of Narcolepsy Symptoms and Fatigue in Patients with Narcolepsy Type 1 Treated with the Orexin 2 Receptor Agonist Alixorexton (ALKS 2680)

Improvement in Patient-reported Cognitive Functioning in Patients with Narcolepsy Type 1 Treated with the Orexin 2 Receptor Agonist Alixorexton (ALKS 2680)

Presenter

Giuseppe Plazzi, MD, PhD

Yves Dauvilliers, MD, PhD

Giuseppe Plazzi, MD, PhD

Please refer to the congress app for the most current scientific session information

Alixorexton

About

World Sleep Day is a global awareness campaign that emphasizes the importance of healthy sleep. Each year on World Sleep Day, World Sleep Society invites advocates, health professionals, and institutions to organize sleep health awareness activities related to the annual theme.

The theme for World Sleep Day 2025 was “Make Sleep Health a Priority.”

What happened on World Sleep Day 2025?

Over 500 advocates from 79 countries signed up to be official World Sleep Day Delegates! Here is just a small sample of what they accomplished:

In Colombia, 13 unique events were coordinated by Dr. Natalia Colorado and the Colombian Association of Sleep Medicine, including conferences, media outreach, and articles.

In Nigeria, Prof. Morenikeji Komolafe organized a healthcare symposium and student outreach sessions in Osun State, helping young people understand the importance of sleep.

In India, Apollo Specialty Hospitals hosted a “pillow parade,” poetry and painting competitions, and a power nap contest.

The Chinese Sleep Research Society livestreamed a major event featuring sleep experts, innovators, and an Olympic athlete.

Save the Date

The next World Sleep Day is March 13, 2026.

Scan the code to become a World Sleep Day Delegate.

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

ASSM 2025 MEETING OVERVIEW

Meeting Dates

Saturday, September 6 and Sunday, September 7

Location

Rooms 328, 329, 330

Suntec Singapore Convention & Exhibition Centre

Registration

ASSM 2025 requires a separate registration from World Sleep 2025. Please visit the registration area on Level 3 if you require a registration.

Registration for ASSM 2025 includes access to all ASSM sessions on Saturday and Sunday, including keynotes, symposia, oral abstracts, poster abstracts, the lunch sessions, and the closing reception. The closing reception will take place at the ASSM session rooms on Sunday evening after the poster hall session concludes.

About ASSM

The Asian Society of Sleep Medicine (ASSM) is the official host society for World Sleep 2025 in Singapore. Founded in 2015, the ASSM promotes all aspects of sleep medicine and research in Asia. The ASSM regularly holds scientific meetings to encourage international exchange and knowledge transfer in sleep medicine, advancing sleep health for all Asian populations.

Organizing Committee

Yuichi Inoue (Japan) – Chair

Ahmed S. BaHammam (Saudi Arabia)

Fang Han (China)

Hiroshi Kadotani (Japan)

KiYoung Jung (Korea)

Leow Leong-Chai (Singapore)

Michael Chee (Singapore)

Naricha Chirakalwasan (Thailand)

SC Hong (Korea)

Stijn Massar (Singapore)

Toh Song Tar (Singapore)

Yukiyoshi Sumi (Japan)

Yun Kwok Wing (Hong Kong)

Yuta Takano (Japan)

Program Committee

Ahmed S. BaHammam (Saudi Arabia)

Duong-Quy Sy (Vietnam)

Fang Han (China)

Hiroshi Kadotani (Japan)

JC Suri (India)

Leow Leong-Chai (Singapore)

Michael Chee (Singapore)

Mohamed A. Al-Abri (Oman)

Naricha Chirakalwasan (Thailand)

Ning-Hung Chen (Taiwan)

Seockhoon Chung (Korea)

Seung Bong Hong (Korea)

Seung-Chul Hong (Korea)

Stijn Massar (Singapore)

Tayard Desudchit (Thailand)

Toh Song Tar (Singapore)

Yuichi Inoue (Japan)

Yuta Takano (Japan)

Yun-Kwok Wing (Hong Kong)

Zhi-Li Huang (China)

MEETING PROGRAM

September

6 – 7, 2025 | Singapore

SATURDAY, SEPTEMBER 6

ASSM 2025 Exhibition

9:00am – 5:00pm | Room 330

ASSM Opening remarks

9:00am – 9:05am | Room 328

Yuichi Inoue (Japan)

ASSM Symposium 1: Current status of narcolepsy and hypersomnolence research in Asia

9:10am – 10:25am | Room 328

Chairs: S.C. Hong (Korea, Republic of), Fang Han (China)

9:10am– 9:25am

Aripiprazole treatment for post-COVID-19 sleep duration prolongation

Takashi Kanbayashi (Japan)

9:25am – 9:40am

The Treatment Outcome of Narcolepsy and Depression with Repetitive Transcranial Magnetic Stimulation (rTMS): A Preliminary Study

Yu Shu Huang (Taiwan)

9:40am– 9:55am

HLA-Associated Autoimmune Disorders in Narcolepsy: Evidence from Nationwide Data in South Korea

S.C. Hong (Korea, Republic of)

9:55am – 10:10am

Psychiatric and Sleep Disturbances in Families of Narcolepsy Patients: Cross-sectional Study

Tae Won Kim (Korea, Republic of)

10:10am– 10:25am

Narcolepsy and the Risk of Pregnancy Complications: Based on a Nationwide Healthcare System Database in South Korea

Young-Chan Kim (Korea, Republic of)

ASSM Oral session 1: Technology, basic, and cognition

9:10am – 10:10am | Room 329

Chair: Zhi-Li Huang (China)

9:10am – 9:19am

Z4IP – Comprehensive Sleep and Activity Phenotyping Through Multifactor Mobile Data Integration

Chun Siong Soon (Singapore)

9:19am – 9:28am

Does self-reported sleep duration reflect actigraphyreported sleep duration in youth male soccer players?

Pedro Figueiredo (United Arab Emirates)

9:28am – 9:37am

Shared genetic architecture between sleep apnea related sleep traits and cardiometabolic diseases

Yuan Zhang (China)

9:37am – 9:46am

Correlation between iron deposition and cognitive function in OSA patients of different severity levels based on quantitative susceptibility mapping.

Shiyuan Gao (China)

9:46am – 9:55am

The Role of Adenosine Receptors and Their Antagonist Caffeine in the Mouse Hippocampal CA2 Region

Associated with Sleep Deprivation

Lik Wei Wong (Singapore)

9:55am – 10:04am

Effects of Combined Chronic Intermittent Hypoxia and Hypercapnia Exposure on Blood Pressure, Systemic Inflammation, and Oxidative Stress Levels in Rats

Junbo Zhang (China)

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

SATURDAY, SEPTEMBER 6

ASSM Symposium 2: Transforming insomnia care: Novel insights and approaches for treatment

10:35am – 11:50am | Room 328

Chairs: Isa Okajima (Japan), Shirley Xin Li (Hong Kong)

10:35am – 10:50am

Role of value clarification/commitment and rule-governed behaviors (tracking) on the insomnia and daytime symptoms

Isa Okajima (Japan)

10:50am – 11:05am

Attrition, adherence, and retention in cognitive behavioural therapy for youth insomnia

Hao Fong Sit (Hong Kong)

11:05am – 11:20am

Stepped care of CBT-I based on systematic reviews

Yuta Takano (Japan)

11:20am – 11:35am

Digital Insomnia Intervention Program Prevents Future

Onset of Major Depressive Disorder in Youth with Insomnia

Sijing Chen (Hong Kong)

11:35am – 11:50am

Digital cognitive-behavioral therapy for insomnia prevents suicidality: evidence from real-world study

Binbin Lei (China)

ASSM Symposium 3: An update of collaborative research studies Across Asia ASSM initiative

10:35am – 11:35am | Room 329

Chair: Yun Kwok Wing (Hong Kong), SB Hong (Korea, Republic of)

10:35am – 10:50am

Cross-cultural differences in sleep patterns and problems in Asian school-aged adolescents - the ACROSS study

Stijn Massar (Singapore)

10:50am – 11:05am

Cross-cultural differences in sleep patterns and problems in Asian school-aged adolescents - the ACROSS study

Rachel Chan (Hong Kong)

11:05am – 11:20am

Clinical characteristics of RLS in Asian countries

Sungeun Hwang (Korea, Republic of)

11:20am – 11:35am

Sleep Medicine Education in Asian Medical Schools

Hamza Dhafar (Saudi Arabia)

MEETING PROGRAM

September

6 – 7, 2025 | Singapore

SATURDAY, SEPTEMBER 6

ASSM Lunch Seminar 1: The Impact of Tongue on sleep apnea: From Pathophysiology to Innovative Therapies

12:00pm – 1:00pm | Room 328

Chair: Ning-Hun Chen (Taiwan), Motoo Yamauchi (Japan)

Supported by Somnics

12:00pm – 12:15pm

Physiological Role of the Tongue in the Pathogenesis of Obstructive Sleep Apnea

Liyue (Adell) Xu (China)

12:15pm – 12:30pm

MRI-Based Assessment of Airway Patency During Sleep

With and Without Pressure Therapy: Role of Tongue and Soft Tissue Structures

Chen Lin (Taiwan)

12:30pm – 12:45pm

Drug-Induced Sleep Endoscopy for Functional Assessment of Intraoral Negative Pressure in OSA Management

Srinivas Kishore (India)

12:45pm – 1:00pm

Tongue based therapy: the Asian experience of hypoglossal nerve stimulus

Motoo Yamauchi (Japan)

1:00pm – 1:00pm

Panel Discussion and Q&A

ASSM Lunch Seminar 2: Orexin/Hypocretin System: Clinical Use

12:00am – 1:00pm | Room 329

Chairs: S.C. Hong (Korea, Republic of), Fang Han (China)

Supported by Yangtze River Pharmaceutical Group

12:00pm – 12:05pm

Introduction

S.C. Hong (Korea, Republic of)

12:05pm – 12:15pm

Significance and Indications of CSF Orexin Measurement

Takashi Kanbayashi (Japan)

12:15pm – 12:30pm

Orexin/Hypocretin Receptors Antagonist for Insomnia: Phase III RCT Evidence of Fazamorexant, a Rapid-Onset, Short-Acting DORA

Wenjun Zhu (China)

12:30pm – 12:45pm

The Current Issues and Future Perspectives of Pharmacological Treatment for CNS Hypersomnias

Yuichi Inoue (Japan)

12:45pm – 1:00pm

Panel Discussion and Audience Q&A

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

SATURDAY, SEPTEMBER 6

ASSM Keynote 1: Stijn Massar: One Million and One Nights: Harnessing Wearable Sleep Tracking Data to Accelerate Population Health Insights

1:10pm – 1:50pm | Room 328

Chair: Ahmed BaHammam (Saudi Arabia)

1:10pm – 1:12pm

Introduction

Ahmed BaHammam (Saudi Arabia)

1:10pm – 1:50pm

One Million and One Nights: Harnessing Wearable Sleep Tracking Data to Accelerate Population Health Insights

Stijn Massar (Singapore)

ASSM Symposium 4: Navigating Insomnia: Characterization and Targeted Interventions in Diverse Age Groups and Comorbidities

2:00pm – 3:00pm | Room 328

Chairs: Jihui Zhang (China), Rachel Chan (Hong Kong)

2:00pm – 2:15pm

Insomnia in Adolescents: Characteristics and Non-Pharmacological Interventions

Rachel Chan (Hong Kong)

2:15pm – 2:30pm

Insomnia in the Elderly: Exploring the Efficacy of Tai Chi and Cognitive Behavioral Therapy for Insomnia

Danny Yu (Hong Kong)

2:30pm – 2:45pm

Managing Insomnia Comorbid with Mood Disorders: Integrative Approaches and Evidence-Based Strategies

Jihui Zhang (China)

2:45pm – 3:00pm

Insomnia and Obstructive Sleep Apnea: Cardiometabolic Risk and Clinical Implication

Yun Li (China)

ASSM Oral session 2: RBD

2:00pm – 3:00pm | Room 329

Chair: Ki-Young Jung (Korea, Republic of)

2:00pm – 2:09pm

Automated analysis of home video for screening REM sleep behaviour disorder

Yonglong Ye (Hong Kong)

2:09pm – 2:18pm

Neural correlates of decisional impulsivity across early stages of α-synucleinopathy: a case-control functional magnetic resonance imaging study

Siyi Gong (China)

2:18pm – 2:27pm

Association Between Iron Metabolism Biomarkers and REM Sleep Behavior Disorder: A Mendelian Randomization Study

Guimei Zhang (China)

2:27pm – 2:36pm

Integrated gut microbiome and metabolome analysis in isolated REM sleep behavior disorder

Bo Li (Hong Kong)

2:36pm – 2:45pm

Sleep Deprivation Accelerates α-Synuclein Pathology via Per2-Mediated Lysosomal Dysfunction in Mice with REM

Sleep Behavior Disorder

Liqing Zhang (China)

MEETING PROGRAM

September

6 – 7, 2025 | Singapore

SATURDAY, SEPTEMBER 6

ASSM Symposium 5: Obstructive sleep apnea in women: clinical practice and basic research

3:15pm – 4:30pm | Room 328

Chairs: Qing Yun Li (China), Naricha Chirakalwasan (Thailand)

3:15pm – 3:30pm

Sex differences of OSA

Qing Yun Li (China)

3:30pm – 3:45pm

Teleportative effects of estrogen on CIH induced endothelial dysfunction

Ying Ni Lin (China)

3:45pm – 4:00pm

Characteristics of OSA in Japanese women and CPAP model selection

Azusa Ikegami (Japan)

4:00pm – 4:15pm

Association between obstructive sleep apnea and the risk of adverse pregnancy outcomes

Yoko Komada (Japan)

4:15pm – 4:30pm

Impact of Treating Obstructive Sleep Apnea on Pregnancy Outcomes

Naricha Chirakalwasan (Thailand)

ASSM Oral session 3: Hypersomnia

3:15pm – 4:15pm | Room 329

Chair: S.C. Hong (Korea, Republic of)

3:15pm – 3:24pm

Clinical Phenotypes and Longitudinal Evolution Patterns in Narcolepsy: A Prospective Cohort Study Based on Symptom Cluster Analysis

Yimeng Zhang (China)

3:24pm – 3:33pm

Weight loss response to GLP-1 RA in adults with narcolepsy cataplexy

Shuying Li (China)

3:33pm – 3:42pm

Hypothalamic Functional Connectivity, Depressive Symptoms, and Post-Treatment SOREMPs in Narcolepsy Type 1: Links to Sleep Latency and Mediation Mechanisms

Mengmeng Wang (China)

3:42pm – 3:51pm

Does body mass index differentiate the clinical and sleep characteristics of Chinese children and adults with narcolepsy type 1 differently?

Min Zhang (China)

3:51pm – 4:00pm

Attention and Inhibition Deficits in Narcolepsy Type 1: Behavioral and Electrophysiological Markers

Zongshan Li (China)

4:00pm – 4:09pm

Nocturnal Fragmentation and Dream Enactment behaviors in Narcolepsy: Diagnostic Biomarkers Associated with Hypocretin-1 Deficiency

Huimin Zhang (China)

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

SATURDAY, SEPTEMBER 6

4:25pm – 5:35pm | Room 329

Chair: Isa Okajima (Japan)

4:25pm – 4:34pm

ASSM Oral session 4: Insomnia and psychiatry

ASSM Symposium 6: Sleep Medicine Education Across Asia: Current Assessment and Strategic Implementation Framework

4:40pm – 5:55pm | Room 328

An AI-Driven Model for Depression Detection Using Sleep Heartbeat and Breathing Signals

Dongbin Lyu (China)

4:34pm – 4:43pm

Cognitive Function and Frontotemporal Functional Connectivity in Patients with Major Depressive Disorder and Comorbid Insomnia Symptoms: A Cerebral Hemodynamics Perspective

Xiaodong Song (China)

4:43pm – 4:52pm

Differential Efficacy of Online Group BBTI on Fatigue and Sleep in Depressed Patients with Insomnia Symptoms Based on Sleep Reactivity: A Pilot Study

Sifan Hu (China)

4:52pm – 5:01pm

Associations of Subjective and Objective Sleep with Impulsivity and Probabilistic Reasoning

Shijie Yu (Hong Kong)

5:01pm – 5:10pm

Subtyping and Prognosis of Insomnia Disorder Based on Clinical, Psychological, and Sleep EEG Features

Dongbin Lyu (China)

5:10pm – 5:19pm

Actigraphy-Derived Circadian Rhythm Patterns as the Predictors of Anxiety and Depression in Individual with Insomnia Symptoms: Results of Principal Component Analysis

Mingqing Zhou (Hong Kong)

5:19pm – 5:28pm

426 Gender Differences in Changes in Sleep-Related Physical and Mental Symptoms and Quality of Life

Following CPAP Treatment in Patients with OSA

Yen-Chin Chen (Taiwan)

Chairs: Ahmed BaHammam (Saudi Arabia), Naricha Chirakalwasan (Thailand)

4:40pm – 4:55pm

Mapping the Current Landscape: Challenges and Opportunities in Asian Sleep Medicine Education

Pei-Lin Lee (Taiwan)

4:55pm – 5:10pm

Implementing the Asian Adult Sleep Medicine Fellowship Curriculum: Strategies for Diverse Healthcare Systems

Ahmed BaHammam (Saudi Arabia)

5:10pm – 5:25pm

Building Excellence in Sleep Technology: Developing Comprehensive Training Programs for Sleep Technologists

Naricha Chirakalwasan (Thailand)

5:25pm – 5:40pm

Sleep Medicine Education in Asian Medical School

Curricula: Current State and Strategic Recommendations for Enhancement

Hamza Dhafar (Saudi Arabia)

5:40pm – 5:55pm

Future Directions: ASSM Accreditation Systems, Certification Pathways, and Regional Collaboration Networks

Ahmed BaHammam (Saudi Arabia)

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

SUNDAY, SEPTEMBER 7

ASSM 2025 Exhibition

8:00am – 5:00pm | Room 330

ASSM Young investigator symposium

8:00am – 9:00am | Room 328

Chairs: Naricha Chirakalwasan (Thailand), Ronald Lee (Singapore)

8:00am – 8:15am

Gut microbiota in major depressive disorders with rapid eye movement behavior disorder: tracing a subtype of depression with underlying neurodegeneration

Yuhua Yang (Hong Kong)

8:15am – 8:30am

Artificial Intelligence Diagnosis of Obstructive Sleep Apnea: Bayesian Meta-Analyses of 80 Studies with 248 Models

Esther Yanxin Gao (Singapore)

8:30am – 8:45am

Nighttime Light Exposure Predicts Higher Sleep Apnea

Risk: A Prospective Study with Explainable Machine Learning

Wei Wang (China)

8:45am – 9:00am

Effectiveness of Stepped-Care Chinese Herbal Medicine and Psychotherapy on Improving Sleep in Adults with Insomnia: A Stepped-Wedge Cluster Randomized Trial

Danny Yu (Hong Kong)

ASSM Oral session 5: SBD 1

8:00am – 9:00am | Room 329

Chair: Ning-Hun Chen (Taiwan)

8:00am – 8:09am

Chronic Intermittent Hypoxia Impairs Genioglossus Activity and Alters Upper Airway Negative Pressure Reflex in a Rat Model

Guoping Yin (China)

8:09am – 8:18am

The Effectiveness of a Smart Sleep Apnoea SelfManagement Support Program (4S) in Improving Cardiovascular Risk and Quality of Life in Subjects with Moderate to Severe Obstructive Sleep Apnea: A Randomized Controlled Trial

Agnes Yuen-kwan Lai (Hong Kong)

8:18am – 8:27am

Comparison of the 1st Half of the Night Polysomnography (3 Hours) vs. Full Night Analysis in Asian Population: A Cohort Study

Sasarak Kijtorntham (Thailand)

8:27am – 8:36am

Higher Ambient Temperatures may Increase Sleep Apnea–Specific Pulse-Rate Response in obstructive sleep apnea. Yanru Li (China)

8:36am – 8:45am

Adenosine A2A Receptor Activation Protects Against Chronic Intermittent Hypoxia Induced Kidney Injury by PKA-ERK1/2 pathway

Xiucui Li (China)

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

SUNDAY, SEPTEMBER

7

ASSM Symposium 7: Neurocognitive Mechanisms and Mental Health Consequences

Associated with Sleep Disturbance in Adolescents

9:10am – 10:10am | Room 328

Chairs: Rachel Chan (Hong Kong), Shirley Xin Li (Hong Kong)

9:10am – 9:25am

Insomnia with Objective Short Sleep Duration in Adolescents: Behavioural and Cortical Arousal Evidence

Yee Lok Wong (Hong Kong)

9:25am – 9:40am

Neurobehavioral functions in sleep-restricted adolescents

June Lo (Singapore)

9:40am – 9:55am

Sleep and Mental Resilience in Adolescents: The Potential Stress Adaptive Role of High Frequency Power in Sleep EEG

Chris Xie Chen (Hong Kong)

9:55am – 10:10am

Subtypes of Insomnia and Objective Short Sleep Duration: Associations with Mental Health Problems in Adolescents

Guanghai Wang (China)

ASSM Oral session 6: SBD 2

9:10am – 10:10am | Room 329

Chair: Leong-Chai Leow (Singapore)

9:10am – 9:19am

Interpretable Machine Learning Using Questionnaire Data: A Scalable Approach for Sleep Apnea Screening

Nhung Huyen Hoang (Japan)

9:19am – 9:28am

Unveiling the circHDAC9/miR-138-5p/SIRT1 Axis: A Novel Mechanism Linking Obstructive Sleep Apnea-Hypopnea Syndrome to Cognitive Impairment through SenescenceAssociated Neuronal Autophagy

Wenqiu Wei (China)

9:28am – 9:37am

Determining the Minimum Nights Required for Reliable Wearable-Based Assessment of Sleep Architecture and HRV in OSA, Insomnia, and COMISA

Hai Ka Betty Young (Hong Kong)

9:37am – 9:46am

Can Awake End-tidal CO2 Predicts Sleep-related Hypoventilation in Children with Neuromuscular Diseases?

Kanjaporn Sirisomboonlarp (Thailand)

9:46am – 9:55am

Association of upper airway morphological phenotypes with obstructive sleep apnea in middle-aged Korean adults

Jisun Choi (Korea, Republic of)

9:55am – 10:04am

Screening prediction models using artificial intelligence for moderate-to-severe obstructive sleep apnea in patients with acute ischemic stroke

Huan Jan Lin (Taiwan)

MEETING PROGRAM

September

6 – 7, 2025 | Singapore

SUNDAY, SEPTEMBER 7

ASSM Keynote 2: Yang Dan:

The How and Why of sleep

10:20am – 11:00am | Room 328

Chair: Zhi-Li Huang (China)

10:20am – 10:22am

Introduction

Zhi-Li Huang (China)

10:22am – 11:00am

The How and Why of sleep

Yang Dan (United States)

ASSM Symposium 8: Restless Legs Syndrome: Clinical Perspectives and Emerging Research

11:20am – 12:20pm | Room 328

Chairs: Ki-Young Jung (Korea, Republic of), Yuichi Inoue (Japan)

11:20am – 11:35am

Prevalence, Presentation, and Correlates of RLS Among Stroke Survivors in India.

Ravi Gupta (India)

11:35am – 11:50am

Circadian Rhythm in Restless Legs Syndrome

Seyoung Bang (Korea, Republic of)

11:50am – 12:05pm

RLS: from phenotype to genotype

Wenjun Zhu (China)

12:05pm – 12:20pm

Japanese RLS guideline update: evidence review and GRADE based recommendations

Yukiyoshi Sumi (Japan)

ASSM Oral session 7: Sleep Health

11:20am – 12:20pm | Room: Room 329

Chair: Hiroshi Kadotani (Japan)

11:20am – 11:29am

Sleep Temporal Entropy: A Novel Sleep Fragmentation

Biomarker Predicting Cardiometabolic Disease and Mortality Risk

Jiong Chen (China)

11:29am – 11:38am

Sleep Stage Classification over Continuous Positive Airway Pressure Signals with Multi-Period Convolutional Neural Network

Yu-Hsin Chen (Taiwan)

11:38am – 11:47am

Effects of a Personalized Sleep Extension Protocol on Sleep Duration and Its Moderators: A Pilot Actigraphy Study

Wei Wang (Hong Kong)

11:47am – 11:56am

Association between snoring and in vitro fertilization outcomes among infertile women

Huanhuan Wang (China)

11:56am – 12:05pm

Structural Factors Impeding or Facilitating Freshmen

Sleep Habits

Chun Siong Soon (Singapore)

12:05pm – 12:14pm

Sleep quality and hypertension: correlation between Pittsburgh Sleep Quality Index (PSQI) scores and the prevalence of hypertension and blood pressure reduction patterns

Kaiyan Ma (China)

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

SUNDAY, SEPTEMBER 7

ASSM Lunch Seminar 3: The Epidemiology, Mechanisms, and Clinical Manifestations of Excessive Daytime Sleepiness

12:30pm – 1:30pm | Room 328

Chairs: Ahmed BaHammam (Saudi Arabia), Yuichi Inoue (Japan)

Supported by Takeda

12:30pm – 12:45pm

Epidemiology of Excessive daytime sleepiness in Asia

Yun Kwok Wing (Hong Kong)

12:45pm – 1:00pm

Characteristics of 24-Hour Melatonin Rhythms in Different Sleep-Related Hypersomnolence Disorders

Shuai Wu (China)

1:00pm – 1:15pm

Narcolepsy spectrum disorder -multifaced aspects of sleepiness

Makoto Honda (Japan)

ASSM Philips Sleeposium: Frontiers of Sleep Sciences in 2025

Pillars of Progress: Patient Safety and OSA Leadership in 2025

12:30pm – 1:30pm | Room 329

Chair: Leow Leong Chai (Singapore)

Supported by Philips

From Testing to Trust: Ensuring Patient Safety

Denver Faulk (United States)

OSA.version.2025: Crucial Conversations

Teofilo Lee-Chiong (United States)

Panel discussion

ASSM Keynote 3: Ki-Young Jung: Restless legs syndrome across Asian countries

1:40pm – 2:20pm | Room 328

Chair: Yuichi Inoue (Japan)

1:40pm – 1:42pm

Introduction

Yuichi Inoue (Japan)

1:42pm – 2:20pm

Restless legs syndrome across Asian countries

Ki-Young Jung (Korea, Republic of)

ASSM Symposium 9: REM sleep, behavior, mood, and neurodegeneration - the path from early to late life

2:30pm – 3:30pm | Room 328

Chair: Gulcin Benbir Senel (Turkey), Garima Shukla (Canada)

2:30pm – 2:45pm

REM sleep behavior disorder and neuropsychiatric comorbidity - lessons from younger populations

Garima Shukla (Canada)

2:45pm – 3:00pm

Clinical characteristics and predictors of phenoconversion in REM sleep behavior disorder - data from different ethnic and geographical origins

Gulcin Benbir Senel (Turkey)

3:00pm – 3:15pm

Polysomnographic markers of neurodegeneration in REM sleep behavior disorder

Ravi Yadav (India)

3:15pm – 3:30pm

How we could support patients with isolated REM sleep behavior disorder in their transitional state from sleep disorders to neurodegenerative diseases?

Naoko Tachibana (Japan)

MEETING PROGRAM

September

6 – 7, 2025 | Singapore

SUNDAY, SEPTEMBER 7

ASSM Oral session 8: Pediatric and chronobiology

2:30pm – 3:30pm | Room 329

Chair: Tayard Desudchit (Thailand)

2:30pm – 2:39pm

Reward processing and eveningness in adolescents: A case-control study with EEG investigation

Fiona Yujing Jin (Hong Kong)

2:39pm – 2:48pm

Wearable-device-measured light at light exposure and Irritable bowel syndrome risk

Nana Zheng (China)

2:48pm – 2:57pm

Impaired attention function and increased REM sleep

EEG Theta/Beta Ratio in pediatric REM sleep-related obstructive sleep apnea

Dandi Ma (China)

2:57pm – 3:06pm

Effects of Ambient Temperature and Pollen Exposure on Sleep, Respiratory Events, and Apnea-Specific Pulse Rate

Response in Children with Sleep Disordered Breathing

Yanru Li (China)

3:06pm – 3:15pm

Pulmonary Rehabilitation in Pediatric Scoliosis: A Prospective Pilot of a Risk-Stratified Perioperative Respiratory Pathway involving polysomnography and transcutaneous carbon dioxide measurements

Neha Mohan Rao (India)

ASSM Case conference

3:40pm – 5:10pm | Room 328

Chairs: Sy Duong-Quy (Vietnam), JC Suri (India)

3:40pm – 3:55pm

OSA-Triggered Sexsomnia: Clinical Recognition of a Hidden Parasomnia

Hamza Dhafar (Saudi Arabia)

3:55pm – 4:10pm

Central hypoventilation syndrome. What if it’s not congenital?

Jindapa Srikajon (Thailand)

4:10pm – 4:25pm

Excessive daytime sleepiness as a clinical manifestation of severe obstructive sleep apnea: a case report

Kiky Monica Soesanto (Indonesia)

4:25pm – 4:40pm

Can REM sleep behavior disorder be observed in Alzheimer’s disease?

Kwang Ik Yang (Korea, Republic of)

4:40pm – 4:55pm

The silent strain: unmasking the hidden obstructive sleep apnea

Linda Soebroto (Indonesia)

4:55pm – 5:10pm

A middle-aged man with sleep disordered breathing, parasomnia, and recurrent respiratory failure

Mayura Nitesnoppakul (Thailand)

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

SUNDAY, SEPTEMBER 7

ASSM Symposium 10: Therapeutic Innovations for Sleep Disorders: From Mechanistic Breakthroughs to Clinical Translations

3:40pm – 4:55pm | Room 329

Chairs: Xiaoqing Hu (Hong Kong), Hongliang Feng (China)

3:40pm – 3:55pm

Impaired memory control and insomnia: A potential new intervention approach

Xiaoqing Hu (Hong Kong)

3:55pm – 4:10pm

Light and circadian rest-activity rhythm disruptions: Mechanisms and interventions

Hongliang Feng (China)

4:10pm – 4:25pm

Efficacy of group-based cognitive behavioural therapy for insomnia with adjunctive bright light therapy in youths with insomnia and eveningness: Results from a randomised controlled trial

Forrest Tin Wai Cheung (United Kingdom)

4:25pm – 4:40pm

Gut microbiota, circadian rhythms and mental health: Insights from community-dwellings samples

Suyi Xie (Hong Kong)

4:40pm – 4:55pm

Human oral, mouth and gut microbiota as therapeutic targets for sleep disorders

Tong Luo (China)

ASSM Closing remarks

6:10pm – 6:20pm | Room 328

Chair: Yuichi Inoue (Japan)

Silver Sponsor

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

ASSM 2025 SPONSORS AND EXHIBITORS

Thank you to the supporters of ASSM 2025 in Singapore! Attendees are encouraged to meet exhibitors in Room 330 (the exhibition room). Coffee will be available on both program days.

aculys.com/en

Development, import, manufacturing, and sales of prescription pharmaceuticals in the neurology area.

asleep.ai/en/home

Asleep is a leading sleep tech company that developed ‘Apnotrack,’ an AI medical device for diagnosing sleep apnea. In clinical trials, the device has proven its high accuracy, recording a sensitivity of 87% and a specificity of 92%. By providing a convenient, non-contact method using only a smartphone, our technology overcomes the high cost and inconvenience of traditional exams. Asleep developed ‘Sleeptrack,’ an AI home solution based on its sleep AI API technology. Our platform analyzes sleep in real-time, enabling seamless control of smart appliances to create the optimal sleep environment. This technology is based on the world’s largest sleep sound dataset. With multiple SCI-level publications and two CES 2025 Innovation Awards, Asleep is a globally recognized leader in sleep technology.

fphcare.com

Fisher & Paykel Healthcare is a medical device manufacturer headquartered in New Zealand. The company designs, manufactures and sells products and systems used in respiratory care, critical care and sleep apnea treatment. Utilizing its proprietary heating and humidification technology, the company provides products in over 120 countries around the world. The company is committed to developing innovative medical devices to improve patients’ quality of life. In particular, the company has unique technologies and products related to OSA masks, contributing to making them comfortable for patients to use at home.

meiji-seika-pharma.co.jp

Beginning with the production of penicillin in 1946, Meiji Seika Pharma has established itself as a leader in the manufacture and sale of antibacterial drugs. The company also supplies high-quality generic drugs and treatments.

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

ASSM 2025 SPONSORS AND EXHIBITORS

philips.com.sg

At Philips, our purpose is to improve people’s health and well-being through meaningful innovation. We aim to improve 2.5 billion lives per year by 2030, including 400 million in underserved communities. As a technology company, we – and our brand licensees – innovate for people with one consistent belief: there’s always a way to make life better.

somnics.com

Resmed.com

Resmed (NYSE, ASX: RMD) creates life-changing health technologies that people love. We’re relentlessly committed to pioneering innovative technology to empower millions of people in 140 countries to live happier, healthier lives. Our AI-powered digital health solutions, cloud-connected devices and intelligent software make home healthcare more personalized, accessible and effective. Ultimately, Resmed envisions a world where every person can achieve their full potential through better sleep and breathing, with care delivered in their own home. Learn more about how we’re redefining sleep health at Resmed.com and follow @Resmed.

Somnics, Inc. is a medical device company founded in 2011. The Somnics specializes in innovative, mask-free therapies for Obstructive Sleep Apnea (OSA) and is the developer of the award-winning iNAP® Sleep Therapy System. The iNAP Sleep Therapy system is a portable, negativepressure oral device delivered through a soft, flexible mouthpiece connected to a handheld console. During sleep, it generates gentle suction within the oral cavity to reposition the tongue and soft palate, thus maintaining an open airway without masks, hoses, or forced airflow. This approach enables natural nasal breathing and quiet, comfortable treatment that’s discreet and travel-friendly. The iNAP is CE-certified and registered in Taiwan, Singapore, Malaysia, and Hong Kong. The devices have secured FDA clearance in the U.S. and comply with ISO 13485, CE, TGA, and GMP standards.

MEETING PROGRAM

September 6 – 7, 2025 | Singapore

Gold Sponsor

Takeda’s passion and expertise across neurology and psychiatry with special focus on sleep-wake disorders, neurodegenerative and rare neurological conditions, drive our commitment to address the unmet needs of these patients. We are dedicated to transforming the lives of patients with neurological diseases through groundbreaking research and innovative treatments that aim to address the profound impact these disorders have on people and society. Our efforts extend beyond therapeutic innovation. We aim to improve health outcomes across the patient journey by building solutionfocused partnerships with industry, academia, health systems and advocacy, educating patients and physicians and broadening access to therapies. We give particular focus to integrating digital solutions including advancing novel biomarkers and digital approaches to improve diagnosis and personalize patient care.

ASSM 2025 SPONSORS AND EXHIBITORS

and healthcare teams to enhance care delivery through training, service support, and patient education. Our focus is on enabling earlier detection, improving therapy access, and helping more patients achieve better sleep. With a strong presence across Asia, The Air Station continues to shape the future of sleep health through trusted partnerships, quality solutions, and a commitment to advancing clinical care.

Sponsor

en.yangzijiang.com

Silver Sponsor

theairstation.com

The Air Station is a regional leader in sleep and respiratory care, working closely with medical specialists and clinical partners to improve the way sleep disorders are diagnosed and managed. We offer a comprehensive range of clinically proven diagnostics, CPAP systems, and therapy solutions to support better patient outcomes. More than a solutions provider, we collaborate with hospitals

As a leading pharmaceutical company in China, Yangtze River Pharmaceutical Group (YRPG) was founded in 1971, and is one of the first Innovative Enterprises in China selected by the Ministry of Science and Technology. Headquartered in Taizhou City, Jiangsu Province. YRPG has over 20 subsidiaries and more than 18,000 employees. The marketing network covers 12 therapeutic areas with 565 specifications, and 104 products are exported to 42 countries or regions. YRPG is dedicated to providing high-quality, effective products and services worldwide, fulfilling the core value of “High Quality, Public Benefits, Continuous Innovation, and Pursuit of Excellence”. We aim to expand international exchange and cooperation, seeking partners worldwide to ensure that YRPG’s high-quality products can benefit people around the globe.

SCIENTIFIC CONTENT

Schedule at a Glance

SATURDAY September 6

Courses | Special Interest Groups | ASSM Meeting

SUNDAY September 7

Courses | Special Interest Groups | ASSM Meeting

Poster Presentations | Opening Ceremony

World Sleep Foundation Award Reception

MONDAY September 8

Keynote Presentations | Symposia | Oral Abstracts

Industry Symposia | Special Interest Groups

Discussion Groups | Poster Presentations

TUESDAY September 9

Keynote Presentations | Symposia | Oral Abstracts

Industry Symposia | Special Interest Groups

Discussion Groups | Poster Presentations | Gala Dinner

WEDNESDAY September 10

Keynote Presentations | Symposia | Oral Abstracts

Industry Symposia | Special Interest Groups | Closing Ceremony

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

Course Faculty

2025 Course Committee

Sonia Ancoli-Israel (United States), Naricha Chirakalwasan (Thailand), Meir Kryger (United States), Clete Kushida (United States), Karen Spruyt (France)

Course faculty listed in alphabetical order.

Sabra Abbott (United States)

Murat Aksu (Türkiye)

Candice Alfano (United States)

Sulaiman S. Alsaif (Saudi Arabia)

Ahmed BaHammam (Saudi Arabia)

Ahmed Yassin Bahgat (United Arab Emirates)

Lucie Barateau (France)

K elly Baron (United States)

Christina Bini (Sweden)

Perran Boran (Türkiye)

Célyne Bastien (Canada)

Diane Boivin (Canada)

Douglas Bradley (Canada)

Oliviero Bruni (Italy)

Daniel Buysse (United States)

Christian Cajochen (Switzerland)

Stephen Carstensen (United States)

Kate Chan (Hong Kong)

Rachel Chan (Hong Kong)

Philip Cheng (United States)

Michael Chee (Singapore)

Jessie Chi (Taiwan)

Mei Sian Chong (Singapore)

Ching Li Chai Coetzer (Australia)

Yufeng Chen (Taiwan)

Heiser Clemens (Germany)

Julia Crawford (Australia)

Yves Dauvilliers (France)

Sean Drummond (Australia)

Danny Eckert (Australia)

Julie Flygare (United States)

Raffaele Ferri (Italy)

Rolf Fronczek (Netherlands)

Diego Garcia Borreguero (Spain)

Jean Louis Giardin (United States)

Cathy Goldstein (United States)

Michael Gradisar (Sweden)

Paul Gringras (United Kingdom)

Michael Grandner (United States)

Ravi Gupta (India)

Fang Han (China)

Clemens Heiser (Germany)

Max Hirshkowitz (United States)

Catherine Hong (Korea, Republic of)

S.C. Hong (Korea, Republic of)

Rosemary Horne (Australia)

Mark Howard (Australia)

Yuichi Inoue (Japan)

Stacey Ishman (United States)

Mary Ip (Hong Kong)

Melinda Jackson (Australia)

Ofer Jacobowitz (United States)

Haitham Jahrami (Bahrain)

Lindsay Jesteadt (United States)

Amy Jordan (Australia)

Kristina Kairaitis (Australia)

Takashi Kanbayashi (Japan)

Michal Khan (Israel)

Jae Kyoung Kim (Korea, Republic of)

Minjee Kim (United States)

Srinivas Kishore (India)

Henri Korkalainen (Finland)

Lynn Koh (Singapore)

Morenikeji Komolafe (Nigeria)

Clete Kushida (United States)

Leon Lack (Australia)

Chee Sing Lee (Singapore)

Jern Lin Leong (Singapore)

Claudio Liguori (Italy)

Stanley Liu (United States)

John Loh (Singapore)

Shaun Loh (Singapore)

Brendan Lucey (United States)

Atul Malhotra (United States)

Mauro Manconi (Switzerland)

Kiran Maski (United States)

Emmanuel Mignot (United States)

Maria Paola Mogavero (Italy)

Charles Morin (Canada)

Sutapa Mukherjee (Australia)

Ariel Neikrug (United States)

Chew Lip Ng (Singapore)

Hanna Ollila (Finland)

Ju Lynn Ong (Singapore)

Judith Owens (United States)

Laura Palagini (Italy)

Chan Soon Park (Korea, Republic of)

John Peever (Canada)

Andrew Phillips (Australia)

Sasikarn Poomkornsarn (Thailand)

Dalva Poyares (Brazil)

Sveta Postnova (Australia)

Federica Provini (Italy)

Dong N. Quang (Vietnam)

Madeline Ravesloot (Netherlands)

Javad Razjouyan (United States)

Shantha Rajaratnam (Australia)

Winfried Randerath (Germany)

Rebecca Robillard (Canada)

Richa Saxena (United States)

Carlos Schenck (United States)

Jessica Schwarts (Brazil)

Hannah Scott (Australia)

Tamar Shochat (Israel)

Alessandro Silvani (Italy)

Narong Simikajoornboon (United States)

Leonard Soh (Singapore)

Virend Somers (United States)

Tar Toh Song (Singapore)

Karen Spruyt (France)

Kingman Strohl (United States)

Alexander Sweetman (Australia)

Robert Thomas (United States)

Annabelle Sok-Yan Tay (Singapore)

Eric Thuler (Brazil)

Song Tar Toh (Singapore)

Leandro Velasco (Brazil)

Olivier Vanderveken (Belgium)

Aleks Videnovic (United States)

Kavitha Venkatnarayan (India)

Guanghai Wang (China)

Yun Kwok Wing (Hong Kong)

John Winkelman (United States)

Juliane Winkelmann (Germany)

Zheyu Xu (Singapore)

Jing Ying Yeh (China)

Mimi Yow (Singapore)

Yu Yuan (Taiwan)

Audrey Yoon (United States)

Yves Dauvilliers (France)

Phyllis C. Zee (United States)

Michelle Zeidler (United States)

Course Overview

SATURDAY September 6, 2025

8:00am – 5:00pm

C-01 Circadian dysfunction in health and disease Room 326

C-02 Year in review Room 309

C-03 AI’s potential to improve sleep research and sleep medicine Room 310

C-25 Cadaveric hands-on workshop at Changi General Hospital Located at offsite venue

8:00am – 12:00pm

C-04 Sleep apnea diagnosis and management: Current treatments Room 311

C-05 Insomnia: Behavioral treatments Room 324

C-06 Pediatric sleep medicine Room 325

1:00pm – 5:00pm

C-07 The future of diagnosis and management of OSA Room 311

C-08 Insomnia: Pharmacological treatments Room 324

C-09 Adolescent sleep medicine Room 325

1:00pm – 6:00pm

C-24 Understanding narcolepsy: A comprehensive clinical update Room 327

Each course requires a separate ticket.

Find complete course details on following pages.

SUNDAY September 7, 2025

8:00am – 5:00pm

C-10 Narcolepsy and other hypersomnias of central origin: From mechanism to management Room 308

C-11 Sleep, aging, and neurodegeneration Room 309

C-12 Sleep-related movement disorders Room 306

8:00am – 12:00pm

C-13 Comorbid insomnia and sleep apnea (COMISA): When common conditions co-occur Room 310

C-14 Dental sleep medicine Room 311

C-15 Wearables and sleep trackers Room 325

C-16 Sleep, psychiatry, and mental health Room 326

C-22 Occupational health and shift work Room 324 1:00pm – 5:00pm

C-17 Cardiovascular consequences of sleep apnea: What is new? Room 310

C-18 Essentials of sleep surgery: Tools, techniques, and tactics Room 311

C-19 Parasomnias Room 324

C-20 Sleep health Room 325

C-21 Genetics and sleep disorders Room 326

2:00pm – 5:00pm

C-23 Navigating your research career: Skill development and career advice for early and mid-career researchers Room 327

FRIDAY

SATURDAY September 6, 2025

Scientific Program | SATURDAY

C-25: Cadaveric hands-on workshop at Changi General Hospital

7:30am – 9:00pm | Off-site Venue

Chairs: Stanley Liu (United States), Jern-Lin Leong (Singapore), Maria Suurna (United States)

7:30am – 8:00am

Registration

8:00am – 8:05am

Welcome

Stanley Liu (United States)

8:05am – 8:45am

Session 1: In-office, minimally invasive RF turbinates, palate, tongue, nasal valve

Chew Lip Ng (Singapore)

Jessie Chi (Taiwan)

Diderot Parreira (Brazil)

8:45am – 10:00am

Session 2: UPPP: Lateral pharyngoplasty, relocation, barbed, etc.

Jing Ying Yeh (China)

Jessica Schwarts (United Arab Emirates)

Vikas Agrawal (India)

Maria Suurna (United States)

10:00am – 10:30am

Session 3: Coblation tongue base

Srinivas Kishore (India), Jessica Schwarts (United Arab Emirates)

10:30am – 11:00am

Demonstration: TORS

John Loh (Singapore), Eric Thuler (Brazil)

11:00am – 12:20pm

Session 4: Hypoglossal nerve stimulation: All approaches inspire & nyxoah & livanova approaches

Clemens Heiser (Germany)

David Kent (United States)

Maria Suurna (United States)

Crystal Cheong (Singapore)

12:20pm – 12:30pm

Networking break

12:30pm – 1:30pm

Lunch and session 5: Virtual surgical planning and custom max expander demo for naso-maxillary expansion (video)

Leandro Velasco (Brazil)

Allen Huang (United States)

Dong N. Quang (Vietnam)

1:30pm – 2:30pm

Session 6: Maxillary expansion: Non-surgical, surgical endoscopic and open

Eric Thuler (Brazil)

Leonard Soh (Singapore)

Sasikarn Poomkornsarn (Thailand)

Stanley Liu (United States)

2:30pm – 3:15pm

Session 7: Genioplasty, Genioglossus

Yufeng Chen (Taiwan)

Dong N. Quang (Vietnam)

Catherine Sung ok Hong (Korea, Republic of)

3:15pm – 4:45pm

Session 8: MMA (Bimax distraction, TMJ replacement)

Lai In Jeni Ho (Hong Kong)

Diderot Parreira (Brazil)

Chee Sing Lee (Singapore)

Faculty Dinner to follow

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SATURDAY

C-02: Year in review

8:00am – 5:00pm | Room 309

Chairs: Sean Drummond (Australia)

8:00am – 8:20am

Introduction

8:20am – 9:00am

Sleep, sleep loss, and cognition

Michael Chee (Singapore)

9:00am – 9:40am

Sleep neuroscience

John Peever (Canada)

9:40am – 10:00am

Question and answer

10:00am – 10:20am Coffee break

10:20am – 11:00am

Sleep and health disparities

Giardin Jean-Louis (United States)

11:00am – 11:40am

Sleep and circadian rhythms

Christian Cajochen (Switzerland)

11:40am – 12:00pm

Question and answer

12:00pm – 1:00pm Lunch break

1:00pm – 1:40pm

Sleep and aging

Tamar Shochat (Israel)

1:40pm – 2:20pm

Latest trends in wearable sleep technology

Hannah Scott (Australia)

2:20pm – 2:40pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

2:40pm – 3:00pm Coffee break

3:00pm – 3:40pm

Sleep-disordered breathing

Winfried Randerath (Germany)

3:40pm – 4:20pm

Insomnia and mental health

Laura Palagini (Italy)

4:20pm – 5:00pm

Question and Answer

C-03: AI’s potential to improve sleep research and sleep medicine

8:00am – 5:00pm | Room 310

Chairs: Amir Sharafkhaneh (United States), Thomas Penzel (Germany)

8:00am – 8:10am

Introduction

Max Hirshkowitz (United States)

8:10am – 8:55am

Mastering machine learning (ML): The future of sleep data analysis

Javad Razjouyan (United States)

8:55am – 9:40am

Generative AI and LLM

Shirin Shafazand (United States)

9:40am – 9:55am Coffee break

9:55am – 10:40am

Deep learning decoded: Elevating sleep analysis to the next level

Henri Korkalainen (Finland)

10:40am – 11:25am

Big data, bigger impact: Transforming sleep research with AI

Ju Lynn Ong (Singapore)

FRIDAY

5,

SATURDAY September 6, 2025

Scientific Program | SATURDAY

11:25am – 12:25pm Lunch

12:25pm – 1:10pm

AI in action: Revolutionizing the diagnosis of sleep disorders

Sulaiman S. Alsaif (Saudi Arabia)

1:10pm – 1:55pm

Personalized sleep medicine: AI-powered treatment strategies

Amir Sharafkhaneh (United States)

1:55pm – 2:10pm Coffee break

2:10pm – 2:55pm

Next-gen sleep monitoring: AI and wearable technology

Thomas Penzel (Germany)

2:55pm – 3:40pm

AI’s role in scientific writing and peer-review: Balancing benefits and risks

Ahmed BaHammam (Saudi Arabia)

3:40pm – 4:25pm

Limitations, legal aspects and dangers of AI use

Haitham Jahrami (Bahrain)

4:25pm – 4:55pm

Question and answer

C-04: Sleep apnea diagnosis and management: Current treatments

8:00am – 12:00pm | Room 311

Chairs: Naricha Chirakalwasan (Thailand),

Atul Malhotra (United States)

8:00am – 8:20am

Introduction

Atul Malhotra (United States)

8:20am – 9:00am

Global trend in obstructive sleep apnea diagnosis

Mary Ip (Hong Kong)

9:00am – 9:40am

Health consequences in obstructive sleep apnea

Kristina Kairaitis (Australia)

9:40am – 10:00am

Question and answer

10:00am – 10:20am Coffee break

10:20am – 11:00am

Positive airway pressure therapy in OSA

Naricha Chirakalwasan (Thailand)

11:00am – 11:40am

Non-positive airway pressure therapy in OSA

Atul Malhotra (United States)

11:40am – 12:00pm

Question and answer

Atul Malhotra (United States), Naricha Chirakalwasan (Thailand)

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

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FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SATURDAY

C-05: Insomnia: Behavioral treatments

8:00am – 12:00pm | Room 324

Chairs: C.M. Yang (Taiwan), Bei Bei (Australia)

8:00am – 8:10am

Introduction

C.M. Yang (Taiwan)

8:10am – 8:50am

Theoretical foundation, assessment, and conceptualization for CBT-I

C.M. Yang (Taiwan)

8:50am – 9:40am

Core components of CBT-I and treatment planning

Bei Bei (Australia)

9:40am – 10:00am

Question and Answer

10:00am – 10:20am

Coffee Break

10:20am – 11:00am

Managing arousal, sleep reactivity, and integrating mindfulness in CBT-I

Philip Cheng (United States)

11:00am – 11:40am

Behavioral sleep medicine in medical and special populations: Tailoring existing approaches for diverse needs

Ariel Neikrug (United States)

11:40am – 12:00pm

Question and Answer

Bei Bei (Australia)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

C-06: Pediatric sleep medicine

8:00am – 12:00pm | Room 325

Chairs: Rosemary Horne (Australia), Michal Kahn (Israel)

8:00am – 8:05am

Introduction

8:05am – 8:45am

Pediatric sleep disordered breathing: Emerging issues

Kate Chan (Hong Kong)

8:45am – 9:25am

Sleep problems from infancy to middle childhood: Is there a skeleton key treatment for all

Michael Gradisar (Sweden)

9:25am – 10:05am

Psychopharmacology in sleepless children with neurodevelopmental disorders: When, which, how?

Paul Gringras (United Kingdom)

10:05am – 10:15am

Discussion / Question and answer

10:15am – 10:30am

Coffee Break

10:30am – 11:10am

The sleepy child: Hypersomnolence in childhood

Kiran Maski (United States)

11:10am – 11:50am

The 4C model of healthy sleep for trauma-exposed children

Candice Alfano (United States)

11:50am – 12:00pm

Question and Answer

SATURDAY September 6, 2025

Scientific Program | SATURDAY

C-01: Circadian dysfunction in health and disease

8:00am – 5:00pm | Room 326

Chairs: Joshua Gooley (Singapore), Phyllis Zee (United States)

8:00am – 8:20am

Introduction

Joshua Gooley (Singapore)

8:20am – 9:00am

The circadian timing system

Joshua Gooley (Singapore)

9:00am – 9:40am

Effects of light on the circadian timing system

Christian Cajochen (Switzerland)

9:40am – 10:00am

Discussion / Question and answer

10:00am – 10:20am

Coffee break

10:20am – 11:00am

Methods for measuring and monitoring circadian rhythms

Andrew Phillips (Australia)

11:00am – 11:40am

The circadian clock and health

Shantha Rajaratnam (Australia)

11:40am – 12:00pm

Discussion / Question and answer

12:00pm – 1:00pm Lunch break

1:00pm – 1:40pm

Circadian regulation of cardiometabolic health

Frank A.J.L. Scheer (United States)

1:40pm – 2:20pm

The circadian clock in ageing and neurodegenerative disease

Aleks Videnovic (United States)

2:20pm – 2:40pm

Discussion / Question and answer

2:40pm – 3:00pm Coffee break

3:00pm – 3:40pm

Circadian rhythm sleep-wake phase disorders

Sabra Abbott (United States)

3:40pm – 4:20pm

Circadian strategies for occupational health and safety

Diane Boivin (Canada)

4:20pm – 4:40pm

Course wrap-up & practice points

4:40pm – 5:00pm

Panel discussion / Question and answer

Global Sleep Leadership Forum: A meeting of associate society members of World Sleep Society

8:00am – 12:00pm | Room 327

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SATURDAY

World Dentofacial Sleep Society (WDSS): Bruxism

9:00am – 5:00pm | Room 308

Chairs: David Tay (Singapore), Mimi Yow (Singapore)

9:00am – 9:45am

Keynote: Why, how and when quantification of sleep bruxism is needed. From mechanism driven and population epidemiological research to the clinic: A bridge to build Gilles J Lavigne (Canada)

9:45am – 10:30am

Non-PSG methods of assessment of bruxism and introduction of the Standardised Tool for the Assessment of Bruxism (STAB). Clinical management of bruxism: A dentist’s perspective

Peter Svensson (Singapore)

10:30am – 11:00am Coffee break

11:00am – 12:00pm

Keynote: Subtleties in PSG Scoring. Could sleep bruxism serve as a protective homeostatic mechanism against obstructive breathing during sleep?

Jerald H. Simmons (United States)

12:00pm – 1:30pm Lunch break

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

1:30pm – 3:00pm

Debate: There is vs is not clinical relevance in the application of Type 1 PSG parameters to current dental & medical diagnosis in the management of patients with sleep bruxism.

Moderators: Gilles J Lavigne (Canada), David Tay (Singapore), Mimi Yow (Singapore)

1:30pm – 2:15pm

Debate participants: Pro position

Leong-Chai Leow (Singapore), Jerald H. Simmons (United States)

2:15pm – 3:00pm

Debate participants: Con position

Peter Svensson (Singapore), Zheyu Xu (Singapore)

3:00pm – 3:20pm

Scoring criteria and case-study in otherwise healthy individuals

Gilles J Lavigne (Canada)

3:20pm – 3:40pm

Scoring criteria and case-study in presence of sleepdisordered breathing

Leong-Chai Leow (Singapore)

3:40pm – 4:00pm

Scoring criteria and case-study in presence of neurological disorders

Zheyu Xu (Singapore)

4:00pm – 4:30pm Tea break

4:30pm – 5:00pm

Expert panel discussion highlighting future directions and interdisciplinary collaboration

Gilles J Lavigne (Canada), Jerald H. Simmons (United States), Peter Svensson (Singapore), David Tay (Singapore), Zheyu Xu (Singapore), Mimi Yow (Singapore), Leong-Chai Leow (Singapore)

FRIDAY September 5, 2025 SUNDAY

SATURDAY September 6, 2025

Scientific Program | SATURDAY

WDSS: Clinical presentations

9:15am – 10:15am | Room 303

9:15am – 9:35am

Effects of Interceptive Orthodontics & Myofunctional therapy in Subjective symptoms of pediatric sleep disordered breathing amongst Indian children

Mihir Shah (India)

9:35am – 9:55am

Unveiling cutting-edge orofacial myofunctional therapy: A novel, evidence-based approach

Ranilo Tuazon (Philippines)

9:55am – 10:15am

Bridging traditions in pediatric sleep care: Evidence-based integration of laser acupuncture, capnometry-guided biofeedback, and interdisciplinary collaboration

Louis Chan (Australia)

WEDNESDAY September 10, 2025

WDSS: Oral appliance therapy in obstructive sleep apnea: An interdisciplinary approach for personalized care

10:30am – 12:00pm | Room 303

Chairs: Ghizlane Aarab (Netherlands), Peter Cistulli (Australia)

10:30am – 10:32am

Introduction

10:32am – 10:52am

Non-invasive methods for predicting outcomes of oral appliance therapy in OSA patients

Olivier Vanderveken (Belgium)

10:52am – 11:12am

Comparative effectiveness of oral appliance therapy versus other treatments for OSA: identifying patient-specific success factors

Hui Chen (China)

11:12am – 11:32am

Dental approaches to tailored oral appliance therapy for OSA patients: integrating patientspecific factors and preferences

Ghizlane Aarab (Netherlands)

11:32am – 11:52am

Precision medicine approaches in obstructive sleep apnea: the role of dentist-sleep physician partnerships

Peter Cistulli (Australia)

11:52am – 12:00pm

Question and answer

WDSS: Lunch Session with Graphy

12:30pm – 1:30 PM | Room 303

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FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SATURDAY

C-07: The future of diagnosis and management of OSA

1:00pm – 5:00pm | Room 311

Chairs: Danny Eckert (Australia), Robert Thomas (United States)

1:00pm – 1:05pm Introduction

1:05pm – 1:45pm

State of the art on OSA endotyping/precision medicine and translation potential

Danny Eckert (Australia)

1:45pm – 2:25pm

New and emerging OSA diagnostics including multi-night monitoring

Ching Li Chai-Coetzer (Australia)

2:25pm – 3:05pm

Sleep tracking and monitoring

Cathy Goldstein (United States)

3:05pm – 3:20pm Coffee break

3:20pm – 4:00pm

Novel approaches to identify and manage downstream consequences of OSA

Robert Thomas (United States)

4:00pm – 4:40pm

New management pathways for CPAP follow-up including digital medicine and multimodal monitoring

Jean-Louis Pépin (France)

4:40pm – 5:00pm

Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

C-08 : Insomnia: Pharmacological treatments

1:00pm – 5:00pm | Room 324

Chairs: David Neubauer (United States), Yun Kwok Wing (Hong Kong)

1:00pm – 1:20pm Introduction

1:20pm – 2:00pm

Insomnia pharmacotherapy in adults

David Neubauer (United States)

2:00pm – 2:40pm

Insomnia pharmacotherapy in children and adolescents

Judith Owens (United States)

2:40pm – 3:00pm Question and Answer

3:00pm – 3:20pm Coffee break

3:20pm – 4:00pm

Hypnotics polypharmacy: Its risk factor and management

Yuichi Inoue (Japan)

4:00pm – 4:40pm

Advantages and disadvantages of combining CBT-I with sleep-promoting medications

Yun Kwok Wing (Hong Kong)

4:40pm – 5:00pm Question and Answer

FRIDAY

SATURDAY September 6, 2025

Scientific Program | SATURDAY

C-09: Adolescent sleep medicine

1:00pm – 5:00pm | Room 325

Chairs: Perran Boran (Türkiye), Judith Owens (United States)

1:00pm – 1:05pm

Introduction

1:05pm – 1:45pm

Sleep and cognitive function in adolescents

Michael Chee (Singapore)

1:45pm – 2:05pm

Transitioning care 1

Narong Simakajornboon (United States)

2:05pm – 2:25pm

Transitioning care 2 (OSA)

Albert Li (China)

2:25pm – 2:40pm

Adolescent sleep health in developing nations 1

Ravi Gupta (India)

2:40pm – 2:55pm

Adolescent sleep health in developing nations 2

Morenikeji Komolafe (Nigeria)

2:55pm – 3:10pm

Question and answer

3:10pm – 3:25pm Coffee break

3:25pm – 3:40pm

Measuring sleep in adolescents

Karen Spruyt (France)

3:40pm – 3:55pm

Challenging insomnia cases 1

Guanghai Wang (China)

3:55pm – 4:10pm

Challenging insomnia cases 2: Complex neurological conditions

Leticia Solter (Brazil)

4:10pm – 4:30pm

Social media and sleep

Rachel Chan (Hong Kong)

4:30pm – 5:00pm Question and Answer

C-24: Understanding narcolepsy: A comprehensive clinical update

1:00pm – 6:00pm | Room 327

Chairs: Raffaele Ferri (Italy), Phyllis C. Zee (United States)

1:00pm – 1:45pm

Understanding narcolepsy: A clinical overview

Takashi Kanbayashi (Japan)

1:45pm – 2:30pm

The diagnostic journey

Kiran Maski (United States)

2:30pm – 3:15pm

Mechanisms of disease: The orexin system

Alessandro Silvani (Italy)

3:15pm – 3:30pm Coffee break

3:30pm – 4:15pm

Diagnostic tools and sleep disorders

Lucie Barateau (France)

4:15pm – 5:00pm

Living with narcolepsy: A patient’s voice

Julie Flygare (United States)

5:00pm – 5:45pm

Guidelines and management strategies

Rolf Fronczek (Netherlands)

5:45pm – 6:00pm

Discussion / Question and answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SATURDAY

WDSS: Challenges in the multidisciplinary management of pediatric SDB: How to phenotype and collaborate

1:30pm – 3:00pm | Room 303

Chair: Wei-Chung Hsu (Taiwan)

1:30pm – 1:32pm

Introduction

1:32pm – 1:52pm

Phenotypes of Pediatric Sleep-disordered breathing

Umakanth Katwa (United States)

1:52pm – 2:12pm

CBCT/CFD images-based prediction model for ped OSA

Wei-Chung Hsu (Taiwan)

2:12pm – 2:32pm

Orthodontic treatment for different phenotypes of pediatric OSA

Audrey Yoon (United States)

2:32pm – 2:52pm

Management of refractory OSA in children

Archwin Tanphaichitr (Thailand)

2:52pm – 3:00pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

WDSS: Upper airway ultrasound in screening, evaluating, guiding management, and assessing treatment effectiveness of obstructive sleep apnea

3:30pm – 5:00pm | Room 303

Chairs: Clete Kushida (United States), Wei-Chung Hsu (Taiwan)

3:30pm – 3:32pm

Introduction

3:32pm – 3:52pm

Use of ultrasound in obstructive sleep apnea patients to evaluate the upper airway and guide treatment

Clete Kushida (United States)

3:52pm – 4:12pm

Screening of underdiagnosed general population for obstructive sleep apnea using upper airway ultrasonography

Wei-Chung Hsu (Taiwan)

4:12pm – 4:32pm

Backscattered ultrasound imaging of tongue in predicting the hypoglossal nerve stimulation treatment outcome

Kurt Tschopp (Switzerland)

4:32pm – 4:52pm

Ultrasound imaging of tongue configuration in predicting the effect of mandibular advancement devices on obstructive sleep apnea treatment

Yunn-Jy Chen (Taiwan)

4:52pm – 5:00pm

Question and answer

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

WDSS: Breakfast Session with SoundHealth

8:00am – 9:00am | Room 303

Global perspectives for sleep technologists: Education, standards, and future growth

8:00am – 12:00pm | Room 327

8:00am – 8:00am

Session 1: Sleep technologists around the world

8:00am – 8:20am

Continuous training, expert certification: What is news in Europe and what we can do to improve as sleep techs worldwide?

8:20am – 8:40am

Sleep Technologists: The relationship between training, skills, and job prospects vs. the accreditation of sleep medicine centers

Paolo Matrigiani (Italy)

8:40am – 9:00am

USA reality: BRPT as a model for training and expert certification around the world

9:00am – 9:20am

Discussion group

9:20am – 9:20am

Session 2: Training

9:20am – 9:40am

PSG and VPSG: New guideline from AASM

9:40am – 10:00am

The role of sleep technologists in pharmacological studies and clinical trials

10:00am – 10:20am

Sleep breathing disorders: MCR as a gold standard for diagnosis and the role of screening devices

Paolo Matrigiani (Italy)

10:20am – 10:40am

MWT and MSLT in adult and pediatric patients: The role and guidelines

MONDAY September 8, 2025

TUESDAY September 9, 2025

10:40am – 11:00am

Discussion group

11:00am – 11:00am

WEDNESDAY September 10, 2025

Session 3: The role on multidisciplinary in sleep medicine

11:00am – 11:20am

Connecting the dots: Multidisciplinary approach to screening, prevention and rehabilitation of sleep disorders

11:20am – 11:40am

Sleep breathing disorders: Treatment in OSA patients with CPAP therapy and interaction with respiratory therapists

C-10: Narcolepsy and other hypersomnias of central origin: From mechanism to management

8:00am – 5:00pm | Room 308

Chairs: Fang Han (China), Morenikeji Komolafe (Nigeria)

8:00am – 8:20am

Introduction

Fang Han (China)

8:20am – 9:00am

Overview of hypersomnia

Kingman Strohl (United States)

9:00am – 9:40am

New Insights in narcolepsy research

Emmanuel Mignot (United States)

9:40am – 10:00am

Question and answer

10:00am – 10:20am

Coffee break

10:20am – 11:00am

Recognition of narcolepsy in children

Yu Shu Huang (Taiwan)

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

11:00am – 11:40am

Progress in medical treatment of narcolepsy and other hypersomnia of central origin

Yves Dauvilliers (France)

11:40am – 12:00pm

Question and answer

12:00pm – 1:00pm

Lunch break

1:00pm – 1:40pm

Narcolepsy and metabolism: What do we know?

Ahmed BaHammam (Saudi Arabia)

1:40pm – 2:00pm

Comorbidity and burden of narcolepsy

S.C. Hong (Korea, Republic of)

2:00pm – 2:20pm

Diagnostic burden and challenges of idiopathic hypersomnia

Lucie Barateau (France)

2:20pm – 2:40pm

Question and answer

2:40pm – 3:00pm

Coffee break

3:00pm – 3:40pm

Challenges in diagnosing and managing narcolepsy in other regions of the world: Africa

Morenikeji Komolafe (Nigeria)

3:40pm – 4:00pm

From isolation to international narcolepsy awareness: The power of peers and role models to build a global movement

Julie Flygare (United States)

4:00pm – 4:20pm

A parent’s journey: From narcolepsy diagnosis to shaping the future of sleep research

Lindsay Jesteadt (United States)

4:20pm – 5:00pm

Question and answer

MONDAY September 8, 2025 TUESDAY September 9, 2025

September 10, 2025

C-11: Sleep aging, and neurodegeneration

8:00am – 5:00pm | Room 309

Chairs: Aleks Videnovic (United States),

Mei Sian Chong (Singapore)

8:00am – 8:10am

Introduction

Aleks Videnovic (United States),

Mei Sian Chong (Singapore)

8:10am – 8:50am

Sleep and rhythms in healthy aging

Minjee Kim (United States)

8:50am – 9:30am

Association between sleep and cognition in older adults

Shuo Qin (Singapore)

9:30am – 9:45am

Question and answer

9:45am – 10:00am

Coffee break

10:00am – 10:40am

Sleep and rhythms in dementias

Brendan Lucey (United States)

10:40am – 11:20am

Obstructive sleep apnea in older adults

Naricha Chirakalwasan (Thailand)

11:20am – 11:35am

Question and answer

11:35am – 12:40pm

Lunch break

12:40pm – 1:10pm

Science year in review

Murat Aksu (Türkiye)

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

1:10pm – 1:50pm

REM sleep behavior disorder

Yun Kwok Wing (Hong Kong)

1:50pm – 2:30pm

RBD and disease modification of synucleinopathies

Aleks Videnovic (United States)

2:30pm – 2:45pm

Question and answer

2:45pm – 3:00pm

Coffee break

3:00pm – 3:40pm

Sleep and circadian disturbances in Parkinson’s disease

Claudio Liguori (Italy)

3:40pm – 4:20pm

Glymphatic system: Relevance for healthy aging and neurodegeneration

Ambra Stefani (Austria)

4:20pm – 4:35pm

Question and answer

4:35pm – 4:55pm

Clinical case vignettes

Murat Aksu (Türkiye), Claudio Liguori (Italy)

4:55pm – 5:00pm

Closing remarks

Aleks Videnovic (United States),

Mei Sian Chong (Singapore)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

C-13: Comorbid insomnia and sleep apnea (COMISA): When common conditions co-occur

8:00am – 12:00pm | Room 310

Chairs: Melinda Jackson (Australia), Leon Lack (Australia)

8:00am – 8:10am

Introduction

Melinda Jackson (Australia)

8:10am – 9:00am

COMISA epidemiology

Alexander Sweetman (Australia)

9:00am – 9:40am

COMISA assessment

Célyne Bastien (Canada)

9:40am – 10:00am

Discussion / Question and answer

10:00am – 10:20am

Coffee break

10:20am – 11:00am

Patient management: Treating insomnia in COMISA

Leon Lack (Australia)

11:10am – 11:40am

Patient management: Treating OSA in COMISA

Michelle Zeidler (United States)

11:40am – 12:00pm

Discussion / Question and answer

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

Supported by

SCAN TO DOWNLOAD THE WORLD SLEEP 2025 APP!

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

C-14: Dental sleep medicine

8:00am – 12:00pm | Room 311

Chairs: Mimi Yow (Singapore),

Stephen Carstensen (United States)

8:00am – 8:20am

Introduction to dental sleep medicine

Stephen Carstensen (United States)

8:20am – 9:00am

Lecture: Sleep bruxism, sleep-related movement disorders, and its neurological associations

Zheyu Xu (Singapore)

9:00am – 9:40am

Repurposing the NTI dental device as a screening tool for REM sleep bruxism and its medical comorbidities

David Tay (Singapore)

9:40am – 10:00am

Panel discussion / Question and answer

10:00am – 10:20am

Coffee break

10:20am – 11:00am

Understanding the paediatric airway in relation to sleep-disordered breathing: Current knowledge and practice

Lynn Koh (Singapore)

11:00am – 11:40am

Childhood sleep-disordered breathing, dentofacial parameters, upper airway space and management

Audrey Yoon (United States)

11:40am – 12:00pm

Question and answer

MONDAY September 8, 2025 TUESDAY September 9, 2025 WEDNESDAY September 10, 2025

C-22: Occupational health and shift work

8:00am – 12:00pm | Room 324

Chairs: Mark Howard (Australia), Sveta Postnova (Australia)

8:00am – 8:20am

Introduction

Mark Howard (Australia), Sveta Postnova (Australia)

8:20am – 9:00am

Shift work, internal desynchrony, and metabolic and cardiovascular health

Hans Van Dongen (United States)

9:00am – 9:40am

Bench to the bedside: Translating individual shiftwork strategies for healthcare workers

Mark Howard (Australia)

9:40am – 10:00am

Discussion / Question and answer

Sveta Postnova (Australia)

10:00am – 10:20am

Coffee break

10:20am – 11:00am

From data to care: Personalized AI models for sleep and mental health in shift workers

Jae Kyoung Kim (Korea, Republic of)

11:00am – 11:40am

Prediction and optimization of circadian health in shift work

Sveta Postnova (Australia)

11:40am – 12:00pm

Discussion / Question and answer

Mark Howard (Australia)

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

C-15: Wearables and sleep trackers

8:00am – 12:00pm | Room 325

Chairs: Michael Chee (Singapore), Cathy Goldstein (United States)

8:00am – 8:05am

Introduction

Michael Chee (Singapore)

8:05am – 8:45am

Multi-sensor wearable health trackers: Measurements and outputs

Mathias Baumert (Australia)

8:45am – 9:25am

Interpreting performance evaluation studies: Choosing the right device for your needs

Ju Lynn Ong (Singapore)

9:25am – 10:05am

Sleep tracker use in healthy individuals

Kelly Baron (United States)

10:05am – 10:15am

Question and answer

10:15am – 10:25am

Coffee break

10:25am – 11:05

Sleep tracker use in patients with sleep disorders and other chronic medical conditions

Cathy Goldstein (United States)

11:05 – 11:45am

Beyond sleep: Leveraging other health applications wearable trackers

Michael Chee (Singapore)

11:45am – 12:00pm

Question and answer

Cathy Goldstein (United States)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

C-16: Sleep, psychiatry, and mental health

8:00am – 12:00pm | Room 326

Chairs: Ahmed BaHammam (Saudi Arabia), Charles Morin (Canada)

8:00am – 8:10am

Epidemiology of sleep and psychiatric disorders

Charles Morin (Canada)

8:10am – 8:50am

The bi-directional relationships between insomnia and major depression: Clinical and diagnostic

Christoph Nissen (Switzerland)

8:50am – 9:30am

Sleep and post-traumatic stress disorders

Laura Palagini (Italy)

9:30am – 9:50am Coffee break

9:50am – 10:30am

Neuropsychiatric manifestations in narcolepsy

Ahmed BaHammam (Saudi Arabia)

10:30am – 11:10am

Sleep in schizophrenia and bipolar disorders

Michael Mak (Canada)

11:10am – 11:50am

Pharmacological and behavioral management of sleep disturbances in psychiatric disorders

Christoph Nissen (Switzerland)

11:50am – 12:00pm

Question and answer

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

C-12: Sleep-related movement disorders

8:00am – 5:00pm | Room 306

Chairs: John Winkelman (United States), Yuichi Inoue (Japan), Raffaele Ferri (Italy)

8:00am – 8:10am

Introduction

8:10am – 8:50am

Clinical and neurophysiological aspects of RLS

Mauro Manconi (Switzerland)

8:50am – 9:30am

Clinical phenotypes of RLS

Elias Karroum (United States)

9:30am – 10:10am

Psychiatric aspects of RLS

Yuichi Inoue (Japan)

10:10am – 10:20am

Discussion / Question and answer

10:20am – 10:40am

Coffee break

10:40am – 11:20am

Pediatric RLS

Oliviero Bruni (Italy)

11:20am – 12:00pm

Movement activity during sleep in RLS

Raffaele Ferri (Italy)

12:00pm – 12:10pm

Discussion / Question and answer

12:10pm – 1:10pm

Lunch break

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

1:10pm – 1:50pm

Pathophysiological substrates of RLS: Insights from animal models

Alessandro Silvani (Italy)

1:50pm – 2:30pm

The omics of RLS

Maria Paola Mogavero (Italy)

2:30pm – 2:40pm

Discussion / Question and answer

2:40pm – 3:00pm Coffee break

3:00pm – 3:40pm RCTs in RLS

Diego Garcia-Borreguero (Spain)

3:40pm – 4:20pm

Treatment guidelines of RLS

John Winkelman (United States)

4:20pm – 5:00pm

Question and Answer

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

WDSS: Clinical presentations

9:15am – 10:15am | Room 303

9:15am – 9:35am

Increased post-treatment REM/NREM AHI ratio in patients with OSA successfully treated with MAD oral appliance: could it be a new PSG phenotype indicating poor upper airway muscle responsiveness?

Meng-Chen Tsou (Taiwan)

9:35am – 9:55am

Evaluation of sleep quality improvement with maxillary skeletal expansion using home sleep test and CBCT airway measurements

Sheetal Patil (United States)

9:55am – 10:15am

Segmental mandibular advancement for moderateto-severe obstructive sleep apnea

Chi Ching Joan Wan (Hong Kong)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

WDSS: Journey of obstructive sleep apnea: From womb to tomb

10:30am – 12:00pm | Room 303

Chairs: Stanley Liu (United States), Nivedita Kumar (India)

10:30am – 10:32am

Introduction

10:32am – 10:48

Pediatric OSA: Pre and Post natal risk factors, screening and early intervention

Kranthi Kumar R (India)

10:48 – 11:04

Orthodontic intervention in OSA: discussion and case presentation for modification of Vertical growth and maxillary expansion for transverse deficiency

Jojo Vallamattam (India)

11:04 – 11:20am

Burden of UARS and OSA on TMD, headaches and orofacial pain, and management in an integrated sleep center

Nivedita Kumar (India)

11:20am – 11:36am

Restoration of nasal breathing in sleep as the foundation of heathy facial and airway growth

Stanley Liu (United States)

11:36am – 11:52am

OSA in Geriatric population: Implications and multidisciplinary management along with prosthetic rehabilitation

Rangarajan Vedantham (India)

11:52am – 12:00pm

Question and answer

WDSS: Lunch Session with Graphy

12:30pm – 1:30 PM | Room 303

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

C-17: Cardiovascular consequences of sleep apnea: What is new?

1:00pm – 5:00pm | Room 310

Chairs: Virend Somers (United States), Kate Chan (Hong Kong)

1:00pm – 1:05pm

Introduction

Virend Somers (United States)

1:05pm – 1:50pm

Sleep apnea in hypertrophic cardiomyopathy: Prevalence, pathophysiology and prognostic implications

Virend Somers (United States)

1:50pm – 2:35pm

Sleep apnea and heart failure

Douglas Bradley (Canada)

2:35pm – 2:45pm Coffee break

2:45pm – 3:30pm

Long-term cardiovascular outcomes of sleep apnea: From childhood to adulthood

Kate Chan (Hong Kong)

3:30pm – 4:15pm

Mandibular advancement versus CPAP for blood pressure control in patients with hypertension and cardiovascular risk

Ronald Lee (Singapore)

4:15pm – 5:00pm

Tirzepatide and cardiovascular outcomes: implications for sleep apnea management

Atul Malhotra (United States)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

C-18: Essentials of sleep surgery: Tools, techniques, and tactics

1:00pm – 5:00pm | Room 311

Chairs: Stanley Liu (United States), Shaun Loh (Singapore), Maria Suurna (United States)

Part 1: How to evaluate and select patients for surger:

1:00pm – 1:20pm

PSG vs HST

Clete Kushida (United States)

1:20pm – 1:40pm DISE

Madeline Ravesloot (Netherlands)

1:40pm – 2:00pm

Endotypes/phenotypes and surgical outcomes

Olivier Vanderveken (Belgium)

Part 2: Role of soft tissue surgery and outcomes

Song Tar Toh (Singapore)

2:00pm – 2:15pm

Evolution of palatal surgery

Ryan Soose (United States)

2:15pm – 2:30pm

Palatal approaches for a single level vs multilevel surgery

Srinivas Kishore (India)

2:30pm – 2:45pm

How to manage the tongue base obstruction

Julia Crawford (Australia)

2:45pm – 3:00pm Coffee break

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

Part 3: Nasal and skeletal surgery for nasal breathing

Ofer Jacobowitz (United States)

3:00pm – 3:15pm

Nasal surgery for OSA

Chan Soon Park (Korea, Republic of)

3:15pm – 3:30pm

Nasal breathing from childhood to adult Stacey Ishman (United States)

3:30pm – 3:45pm

Naso-maxillary expansion for SDB

Stanley Liu (United States)

Part 4: Advances in neurostimulation in treatment of sleep apnea

4:00pm – 4:15pm

Evolution of hypoglossal nerve in Asia

Shaun Loh (Singapore)

4:15pm – 4:30pm

Combination procedures with Hypoglossal Nerve Stimulation

Maria Suurna (United States)

4:30pm – 4:45pm

Unilateral vs bilateral neurostimulation for sleep apnea

Clemens Heiser (Germany)

4:45pm – 5:00pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

C-19: Parasomnias

Room 324 | 1:00pm – 5:00pm

Chairs: Carlos Schenck (United States), Federica Provini (Italy)

1:00pm – 1:20pm

Introduction

Carlos Schenck (United States)

1:20pm – 2:00pm Disorders of arousal from NREM sleep

Federica Provini (Italy)

2:00pm – 2:40pm REM sleep behavior disorder (RBD)

Carlos Schenck (United States)

2:40pm – 3:00pm Coffee break

3:00pm – 3:40pm Sleep related eating disorder (SRED)

Yuichi Inoue (Japan)

3:40pm – 4:20pm Nightmares

Brigitte Holzinger (Austria)

4:20pm – 4:40pm Question and answer

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FRIDAY September 5, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

C-20: Sleep health

1:00pm – 5:00pm | Room 325

Chairs: Daniel Buysse (United States), Rebecca Robillard (Canada)

1:00pm – 1:15pm

Introduction

Rebecca Robillard (Canada)

1:15pm – 1:55pm

Sleep health: From concept to clinic to public health

Daniel Buysse (United States)

1:55pm – 2:35pm

Sleep health: Implications for population health and prevention

Yu Sun Bin (Australia)

2:35pm – 2:55pm

Discussion / Question and answer

2:55pm – 3:15pm Coffee break

3:15pm – 3:55pm

Sleep health implications for cardiometabolic and other medical conditions

Arezu Najafi (Iran)

3:55pm – 4:35pm

Sleep health implications for mental health

Michael Grandner (United States)

4:35pm – 5:00pm

Discussion / Question and answer

C-21: Genetics and sleep disorders

1:00pm – 5:00pm | Room 326

Chairs: Juliane Winkelmann (Germany), Sutapa Mukherjee (Australia)

1:00pm – 1:10pm

Introduction

Juliane Winkelmann (Germany), Sutapa Mukherjee (Australia)

1:10pm – 2:00pm

Genetics of insomnia

Richa Saxena (United States)

2:00pm – 2:50pm

Genetics of OSA

Hanna Ollila (Finland)

2:50pm – 3:10pm Coffee break

3:10pm – 4:00pm Genetics of narcolepsy

Emmanuel Mignot (United States)

4:00pm – 4:50pm Genetics of restless legs

Juliane Winkelmann (Germany)

4:50pm – 5:00pm

Discussion / Question and answer

FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | SUNDAY

WDSS: The rationale of Orofacial myofunctional therapy (OMT) in a combined modality treatment in OSA; A new perspective

1:30pm – 3:00pm | Room 303

Chairs: Harald Hrubos-Strøm (Norway), Susana Falardo (Portugal)

1:30pm – 1:32pm Introduction

1:32pm – 1:48pm

Impaired muscle responsiveness in OSA: an endotype for targeted combined modality treatments

Venkata Koka (France)

1:48pm – 2:04pm

Rationale in the selection of targeted oropharyngeal exercises in OSA treatment

Susana Falardo (Portugal)

2:04pm – 2:20pm

Facilitators and barriers to orofacial myofunctional therapy adherence in OSA

Harald Hrubos-Strøm (Norway)

2:20pm – 2:36pm

Devices and AI for myofunctional therapy in OSA

Chu Qin Phua (Singapore)

2:36pm – 2:52pm

A consensus for OMT in a multidisciplinary and multimodality approach in OSA

Triin Jagomägi (Estonia)

2:52pm – 3:00pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

C-23: Navigating your research career: Skill development and career advice for early and mid-career researchers

2:00pm – 5:00pm | Room 327

Chairs: Christina Bini (Sweden), Nicole Grivell (Australia)

2:00pm – 2:50pm

Navigating the research career pathway

Fang Han (China), Yun Shen (China), Kavitha Venkatnarayan (India)

2:50pm – 3:05pm Coffee break

3:05pm – 3:45pm

Developing research skills

Danny Eckert (Australia), Thomas Penzel (Germany)

3:45pm – 4:00pm Coffee break

4:00pm – 5:00pm

Getting answers to hard questions

Amy Jordan (Australia), Charles Morin (Canada), Dalva Poyares (Brazil)

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Scientific Program | SUNDAY

WDSS: COMISA: Updates for dental practice

3:30pm – 5:00pm | Room 303

Chairs: Miguel Meira e Cruz (Portugal), Alexander Sweetman (Australia)

3:30pm – 3:32pm Introduction

3:32pm – 3:52pm When insomnia and sleep apnea meet together

Alexander Sweetman (Australia)

3:52pm – 4:12pm Orofacial aspects of COMISA: pathways and clinical pictures

Miguel Meira e Cruz (Portugal)

4:12pm – 4:32pm

Bruxism, insomnia, and sleep apnea

Cibele Dal Fabbro (Canada)

4:32pm – 4:52pm COMISA interaction with surgical outcomes

Pedro Oliveira (United States)

4:52pm – 5:00pm Question and answer

Poster abstract group 1

5:00pm – 6:00pm | Hall 405 Opening ceremony

6:30pm – 8:15pm | Hall 405

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

K-01: Thomas Penzel

Innovations in sleep technology: Advancing diagnosis and treatment of sleep disorders

8:00am – 8:45am | Hall 406 C

8:00am – 8:02am

Introduction

Michael Chee (Singapore)

8:02am – 8:45am

Innovations in sleep technology: Advancing diagnosis and treatment of sleep disorders

Thomas Penzel (Germany)

K-02: Russell Foster

Light, circadian rhythms and sleep: Fundamental mechanisms to new therapeutics

8:00am – 8:45am | Hall 406 D

8:00am – 8:02am

Introduction

Phyllis C. Zee (United States)

8:02am – 8:45am

Light, circadian rhythms and sleep: Fundamental mechanisms to new therapeutics

Russell Foster (United Kingdom)

Exhibit Hall

8:30am – 3:30pm | Hall 405

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-01: Pharmacotherapy of obstructive sleep apnea in 2025

9:00am – 10:30am | Hall 406 C

Chairs: Atul Malhotra (United States), Vsevolod Polotsky (United States)

9:00am – 9:02am

Introduction

9:02am – 9:18am

GLPR1 agonists in OSA

Atul Malhotra (United States)

9:18am – 9:34am

A combination of antimuscarinic agents with selective norepinephrine reuptake inhibitors to treat OSA

Ana Sanchez-Azofra (United States)

9:34am – 9:50am

Carbonic anhydrase inhibitors to treat OSA

Jan Hedner (Sweden)

9:50am – 10:06am

Treating sleepiness in OSA: Is it worth it?

Julia Chapman (Australia)

10:06am – 10:22am

Drug development in OSA: What else in the pipeline?

Vsevolod Polotsky (United States)

10:22am – 10:30am

Question and Answer

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FRIDAY September 5, 2025 SATURDAY September 6, 2025 SUNDAY

Scientific Program | MONDAY

S-02: The Global Adolescent Sleep Project (GASP): A Summary of the Findings, Research Gaps and Future Directions

9:00am – 10:30am | Hall 406 D

Chair: Judith Owens (United States)

9:00am – 9:02am

Introduction

9:02am – 9:18am

1) Introduction: Goals and Methods; 2) Summary and Next Steps

Judith Owens (United States)

9:18am – 9:34am

Sleep and Mental/Behavioral Health

Magda LaHorgue Nunes (Brazil)

9:34am – 9:50am

Accidental Injuries and Immune Function and Infection

Saadoun Bin Hasan (Kuwait)

9:50am – 10:06am

Sleep and Cognition/Learning and Academic Achievement

Karen Spruyt (France)

10:06am – 10:22am

Sleep and Obesity, Cardiovascular and Metabolic Function

Chris Xie Chen (Hong Kong)

10:22am – 10:30am

Question and Answer

WEDNESDAY September 10, 2025

S-03: Challenges of using cognitive behavioral treatment for insomnia in specific patient groups and settings

9:00am – 10:30am | Nicoll 1

Chairs: Kai Spiegelhalder (Germany),

Shirley Xin Li (Hong Kong)

9:00am – 9:02am Introduction

9:02am – 9:18am

Challenges of cognitive behavioural treatment for insomnia in adolescents

Shirley Xin Li (Hong Kong)

9:18am – 9:34am

Challenges of cognitive behavioural treatment for insomnia in primary care

Charles Morin (Canada)

9:34am – 9:50am

Challenges in adapting cognitive behavioural treatment for perinatal insomnia

Bei Bei (Australia)

9:50am – 10:06am

Challenges of cognitive behavioural treatment for insomnia in shift workers

Kai Spiegelhalder (Germany)

10:06am – 10:22am

Challenges of cognitive behavioural treatment for insomnia in psychiatric inpatients with comorbid conditions

Elisabeth Hertenstein (Switzerland)

10:22am – 10:30am

Question and Answer

FRIDAY

Scientific Program | MONDAY

S-04: WSS Task Force recommendations for use of consumer health trackers for sleep tracking

9:00am – 10:30am | Nicoll 2

Chairs: Michael Chee (Singapore), Clete Kushida (United States)

9:00am – 9:02am

Introduction

9:02am – 9:18am

Rationale and scope of recommendations

Michael Chee (Singapore)

9:18am – 9:34am

Using wearable sleep data from healthy persons

Cathy Goldstein (United States)

9:34am – 9:50am

Using sleep trackers in persons with sleep disorders or medical conditions

Kelly Baron (United States)

9:50am – 10:06am

Reading a performance evaluation and selecting an appropriate device

Mathias Baumert (Australia)

10:06am – 10:22am

Ingesting sleep data into clinical records

Thomas Penzel (Germany)

10:22am – 10:30am

Question and Answer

S-05: OSA, neurodegeneration and neurocognitive decline: New insights and future directions

9:00am – 10:30am | Nicoll 3

Chairs: Najib Ayas (Canada), Sutapa Mukherjee (Australia)

9:00am – 9:02am

Introduction

9:02am – 9:18am

How does OSA lead to neurodegeneration?

Discussion of mechanisms of oxidative stress to glymphatics.

Camilla Hoyos (Australia)

9:18am – 9:34am

Can physiologic biomarkers from polysomnography predict neurodegeneration?

Najib Ayas (Canada)

9:34am – 9:50am

Predicting and monitoring neurodegeneration with plasma biomarkers

Andrew Varga (United States)

9:50am – 10:06am

Predicting neurocognitive response to CPAPA step towards precision medicine?

Klar Yaggi (United States)

10:06am – 10:22am

Questions and discussion session

Sutapa Mukherjee (Australia)

10:22am – 10:30am

Question and Answer

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FRIDAY September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

S-06: Sleep health and aging: A decade research and its global implications

9:00am – 10:30am | Room 303

Chairs: Daniel Buysse (United States), Soomi Lee (United States)

9:00am – 9:02am

Introduction

9:02am – 9:18am

Lessons Learned from a Decade of Research on Sleep Health

Daniel Buysse (United States)

9:18am – 9:34am

Genetic basis of multi-dimensional sleep health

Heming Wang (United States)

9:34am – 9:50am

Exploring Generational Variations in Multidimensional Sleep Health: Insights from Epidemiological Data of the Japanese Adults Population

Ryuji Furihata (Japan)

9:50am – 10:06am

Sleep Health Profiles, Pain, and Chronic Conditions: Evidence from US and Asian Countries

Soomi Lee (United States)

10:06am – 10:22am

Poor sleep is associated with faster aging in three independent samples of adults

Aric Prather (United States)

10:22am – 10:30am

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-07: Hypersomnolence in focus: Orexin as the key to treating comorbidities and secondary diseases?

9:00am – 10:30am | Room 308

Chairs: Anna Heidbreder (Austria), Lucie Barateau (France)

9:00am – 9:02am

Introduction

9:02am – 9:22am

Orexin as a key mechanism: Influence on comorbid and disease-immanent disorders in hypersomnolence

Jari Gool (Netherlands)

9:22am – 9:42am

Narcolepsy and cardiovascular risk: Links between hypersomnolence and cardiovascular disease

Poul Jørgen Jennum (Denmark)

9:42am – 10:02am

Mental comorbidities in narcolepsy: Depression, anxiety disorders and the impact of orexin on psychiatric health

Anna Heidbreder (Austria)

10:02am – 10:22am

Therapeutic approaches in narcolepsy: New perspectives through orexin receptor agonists and their significance for the treatment of comorbidities

Lucie Barateau (France)

10:22am – 10:30am

Question and Answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

S-08: Decoding neurological sleep disorders:

Genetic and omics approaches to advance clinical practice

9:00am – 10:30am | Room 309

Chairs: Hanna Ollila (Finland), Richa Saxena (United States)

9:00am – 9:02am

Introduction

9:02am – 9:22am

Shared and Unique Genetic Mechanisms Between Self-Reported or Clinical Insomnia

Richa Saxena (United States)

9:22am – 9:42am

Genetic Mechanisms in Bruxism and Clinical Implications

Tommi Strausz (United States)

9:42am – 10:02am

Narcolepsy: Mechanisms and Translational Advances

Emmanuel Mignot (United States)

10:02am – 10:22am

ME/CFS and Long COVID: Genetic and Omics Insights

Vilma Lammi (Finland)

10:22am – 10:30am

Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-09: The medical and dental aspects of Asian and Caucasian populations in cardiosleep outcomes with oral appliance therapy on sleepdisordered breathing, blood pressure control, and maladaptive myocardial remodelling

9:00am – 10:30am | Room 324

Chairs: Mimi Yow (Singapore), Jing-Hao Ng (Singapore)

9:00am – 9:02am

Introduction

9:02am – 9:22am

Medical aspects of oral appliance therapy in a randomized, controlled, non-inferiority trial of patients with OSA and health morbidities in Asia

Yihui Ou (Singapore)

9:22am – 9:42am

Considerations in oral appliance design for different populations in the management of sleep-disordered breathing

Simona Orlej (Czech Republic)

9:42am – 10:02am

Phenotyping patients with sleep-disordered breathing disorders for management with oral appliances

May-Nak Lau (Malaysia)

10:02am – 10:22am

British airways – Medical effects and dental outcomes of oral appliances in Caucasians with sleep-disordered breathing

Lindsay Winchester (United Kingdom)

10:22am – 10:30am

Question and Answer

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FRIDAY

September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

S-10: Mechanisms underlying REM sleep memory modification

9:00am – 10:30am | Room 325

Chairs: Lucia Talamini (Netherlands), Gina Poe (United States)

9:00am – 9:02am

Introduction

9:02am – 9:22am

A unique role for REM sleep in memory modification; findings from targeted memory reactivation studies

Penny Lewis (United Kingdom)

9:22am – 9:42am

Theta phase-locked memory reactivation during REM sleep reduces memories’ emotional tone

Lucia Talamini (Netherlands)

9:42am – 10:02am

Critical dynamics during REM sleep

Antione Adamantidis (Switzerland)

10:02am – 10:22am

Local interneurons governing REM functions in memory consolidation versus clearance

Gina Poe (United States)

10:22am – 10:30am

Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-11: Prefrontal cortical orchestration of sleep: The missing link between sleep disruption and psychiatric disease?

9:00am – 10:30am | Room 326

Chairs: Lukas Krone (United Kingdom), Franz Weber (United States)

9:00am – 9:02am

Introduction

9:02am – 9:18am

Bidirectional regulation of NREM sleep by prefrontal cortex pyramidal neurons

Lukas Krone (United Kingdom)

9:18am – 9:34am

Prefrontal-hypothalamic dynamics regulating REM sleep

Franz Weber (United States)

9:34am – 9:50am

Prefrontal synaptic regulation of homeostatic sleep pressure

Shoi Shi (Japan)

9:50am – 10:06am

Early life sleep is critical for mPFC development and species-typical social behavior in the monogamous prairie vole

Miranda Lim (United States)

10:06am – 10:22am

Role of prefrontal cortex somatostatin neurons directing top-down control of sleep preparatory behaviour and sleep

Kyoko Tossell (United Kingdom)

10:22am – 10:30am Question and Answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

O-01: Advancing surgical and neurostimulation therapies for obstructive sleep apnea

9:00am – 10:30am | Room 327

Chairs: Ofer Jacobowitz (United States)

9:00am – 9:13am

Next-Generation Hypoglossal Nerve Stimulation Therapy for the Treatment of Obstructive Sleep Apnea

Shaun Loh (Singapore)

9:13am – 9:26am

Efficacy of H-UPPP in obstructive sleep apnea patients with epiglottic collapse

Di Zhao (China)

9:26am – 9:39am

Low Arousal Threshold as a Predictor of Hypoglossal Nerve Stimulation Therapy Adherence

Thomas Kaffenberger (United States)

9:39am – 9:52am

The ‘USA’ System: A Novel Classification for Hypoglossal Nerve Stimulation Therapy Outcomes

Ryan Soose (United States)

9:52am – 10:05am

Combined Hypoglossal Nerve and Ansa Cervicalis

Stimulation Outperforms Single Interventions in Maintaining Airway Patency in Patients with Obstructive Sleep Apnea

Yike Li (United States)

10:05am – 10:18am

International expert consensus statement: surgical failure in obstructive sleep apnea

Tiziano Perrone (Italy)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-02: Orexin-based therapies and pharmacological advances in narcolepsy

9:00am – 10:30am | Room 328

Chairs: Michael Thorpy (United States), Christelle Peyron (France)

9:00am – 9:13am

Oveporexton (TAK-861) Improves Wakefulness in People with NT1: Assessment of At-home Napping and In-clinic Microsleeps

Brian Tracey (United States)

9:13am – 9:26am

Initial preclinical development of a novel dual orexin receptor agonist

Alessandro Silvani (Italy)

9:26am – 9:39am

Optogenetic activation of the histaminergic system in the amygdala of narcoleptic mice reduces the occurrence of cataplexy

Christelle Peyron (France)

9:39am – 9:52am

The Effect of Pitolisant on Sleep-Promoting Neurons

Thomas Scammell (United States)

9:52am – 10:05am

iSPHYNCS: An Update on the Internationalization and New Approaches of the Swiss Primary HYpersomnolence and Narcolepsy Cohort Study

Markus Schmidt (Switzerland)

10:05am – 10:18am

E2086, a Selective Orexin Receptor-2 Agonist, Study for Promoting Wakefulness in Patients With Narcolepsy Type-1

Jocelyn Cheng (United States)

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FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

O-03: Sleep health trajectories in childhood and adolescence

9:00am – 10:30am | Room 329

Chair: Oliviero Bruni (Italy), Paul Gringras (United Kingdom)

9:00am – 9:13am

Relationships between childhood sleep health and mental health at 12-years: Findings from the Growing Up in New Zealand study

Diane Muller (New Zealand)

9:13am – 9:26am

Perinatal Subjective Sleep Disturbance and Circulating Cytokine Levels: Bidirectional Examinations

Michele Okun (United States)

9:26am – 9:39am

Bi-directional associations between physical activity and sleep in school-age children: differences across times of day

Jia Xu Toby Seah (Singapore)

9:39am – 9:52am

Bedtime at Midnight: Actigraphy-Measured Sleep Dimensions and Socioeconomic Predictors among Toddlers in Dhaka, Bangladesh

Ayesha Sania (United States)

9:52am – 10:05am

Exploring the Sleep of Young Children in Aotearoa

New Zealand: Associations with Ethnicity and Maternal Depression in and Beyond the Perinatal Period

Mikaela L. Carter (New Zealand)

10:05am – 10:18am

Sleep Health Profile In Early Infancy Is Associated With Emerging Executive Function Development

Nicolò Pini (United States)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-04: Basic Science: Sleep deprivation and sleep disorder

9:00am – 10:30am | Room 330

Chairs: Luis de Lecea (United States)

9:00am – 9:13am

Maternal sleep disordered breathing impacts cortisol regulation in pregnancy

Margaret Bublitz (United States)

9:13am – 9:26am

THC and CBD in insomnia associated to neuropathic pain: effect on sleep architecture and descending anti-nociceptive pathways

Martha Lopez-Canul (Canada)

9:26am – 9:39am

Data-Driven Fatigue Management: Harmonising Predictive Models with Actual Pilot Data to Optimise Alertness and Performance

Paul Kirby (Australia)

9:39am – 9:52am

Effects of Sleep Deprivation on Cognitive Performance and Neurovascular Coupling: A Functional Transcranial Doppler Study

Kannaphob Ladthavorlaphatt (Thailand)

9:52am – 10:05am

Sleep architectural changes during recurrent cycles of sleep restriction: comparing stable and variable short sleep schedules

Tiffany B. Koa (Singapore)

10:05am – 10:18am

Dopaminergic Mechanisms Underpinning Excessive Daytime Sleepiness and Hypoglossal Nerve

Stimulation Outcomes in OSA: Evidence from Transcriptomics and Animal Models

Yan Wang (China)

FRIDAY

September 5, 2025 SATURDAY September 6, 2025

September 7, 2025 MONDAY September 8, 2025

Scientific Program | MONDAY

S-12: Narcolepsy: Examining the science, impact, and current unmet needs

10:45am – 12:15pm | Hall 406 C

Chairs: Raffaele Ferri (Italy), Phyllis C. Zee (United States)

S-12 is a Takeda-Sponsored Scientific Session.

10:45am – 10:47am

Introduction

10:47am – 11:03am

The orexin system: Foundation of NT1 pathophysiology and therapeutic avenues

Emmanuel Mignot (United States)

11:03am – 11:19am

Narcolepsy across the lifespan: Pediatric and adult perspectives

Kiran Maski (United States)

11:19am – 11:35am

Clinical heterogeneity in narcolepsy: Implications for diagnosis and management

Claudio Bassetti (Switzerland)

11:35am – 11:51am

Genetics and autoimmunity in narcolepsy: Insights from Asian cohorts

Makoto Honda (Japan)

11:51am – 12:07pm

Innovations in narcolepsy treatment: From evidence to implementation

Yves Dauvilliers (France)

12:07pm – 12:15pm

Question and answer

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-13: World Health Organization report on road safety: Pathway to global professional driver work hours regulations

10:45am – 12:15pm | Hall 406 D

Chairs: Mark Howard (Australia), Arezu Najafi (Iran)

10:45am – 10:47am

Introduction

10:47am – 11:03am

WHO global report on road safety: Current professional driver work hours legislation and future targets

Fangfang Luo (China)

11:03am – 11:19am

Continuous drowsiness monitoring to assess work hours impact on professional driver drowsiness: A naturalistic study

Mark Howard (Australia)

11:19am – 11:35am

Applying guidelines for work shift and break duration to professional driver work hours regulations

Hans Van Dongen (United States)

11:35am – 11:51am

Panel discussion/presentation: Pathway to global professional driver work hours regulations: Regulations and challenges in Nigeria

Morenikeji Komolafe (Nigeria)

11:51am – 12:07pm

Panel discussion/presentation: Pathway to global professional driver work hours regulations: Regulations and challenges in China

Fang Han (China)

12:07pm – 12:15pm

Question and Answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

S-14: 45 years on from CPAP: Therapeutic options for pediatric OSA

10:45am – 12:15pm | Nicoll 1

Chairs: Jasneek Chawla (Australia), Moya Vandeleur (Australia)

10:45am – 10:47am

Introduction

10:47am – 11:07am

CPAP in pediatric OSA- What have we learnt?

Karen Waters (Australia)

11:07am – 11:27am

Positional therapy for pediatric OSA

Lena Xiao (Canada)

11:27am – 11:47am

Heated humidified high flow nasal cannula therapy in children with OSA

Indra Narang (Canada)

11:47am – 12:07am

The controversy around orthodontic treatment for OSA in children

Fernanda Almeida (Canada)

12:07pm – 12:15pm

Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-15: Sleep loss increases intrusive memories: But, how?

10:45am – 12:15pm | Nicoll 2

Chairs: Sean Drummond (Australia), Jessica Ogden (Australia)

10:45am – 10:47am

Introduction

10:47am – 11:07am

The impact of time of day and sleep architecture on the frequency and intensity of intrusions following an analogue trauma exposure

Jessica Paterson (Australia)

11:07am – 11:27am

Cognitive consequences of local sleep: From mental fatigue to hypersomnia’s Arthur LeCoz (France)

11:27am – 11:47am

Day-to-day relationships between sleep and intrusive memories following experimental trauma exposure

Jessica Ogden (Australia)

11:47am – 12:07pm

The effects of sleep restriction and insomnia disorder on intrusive memories for emotional scenes

Tony Cunningham (United States)

12:07pm – 12:15pm

Question and Answer

FRIDAY

Scientific Program | MONDAY

S-16: Sleep and health problems among shift workers across the world: Novel findings, challenges, and future perspectives

10:45am – 12:15pm | Nicoll 3

Chairs: Bjørn Bjorvatn (Norway), Siri Waage (Norway)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Transitioning into shift work: Sleep and mental health challenges in new shift workers in Australia

Alexander Wolkow (Australia)

11:07am – 11:27am

The impact of short rest periods between shifts (e.g., quick returns) on sickness absence, sleep, sleepiness and work-related fatigue

Ingebjørg LR Djupedal (Norway)

11:27am – 11:47am

How start times and recovery periods determine sleep duration in shift workers

John Axelsson (Sweden)

11:47am – 12:07pm

Combining behavioral and circadian approaches to improve sleep and mental health in shift workers

Annie Vallières (Canada)

12:07pm – 12:15pm

Question and Answer

S-17: Discussion group: Leading the charge: Sleep medicine’s role in a healthier planet

10:45am – 12:15pm | Room 303

Chairs: Timothy Morgenthaler (United States), Teofilo Lee-Chiong (United States),

Allan O’Bryan (United States)

10:45am – 10:55am

Introduction

Timothy Morgenthaler (United States)

10:55am – 11:15am

Environmental impacts of therapy for OSA: Energy costs of PAP therapy, and how to minimize them

Maxime Patout (France)

11:15am – 11:35am

Sustainable Practices in OSA Therapy: Wastes in the sleep lab and beyond

Laura Donahue (United States)

11:35am – 11:55am

Sustainability Programs in the Medical Device

Industry: General requirements and framework for sustainability for medical devices

Jeremy Wong (United States)

11:55am – 12:10am

Panel and Audience Discussion

Timothy Morgenthaler (United States)

Teofilo Lee-Chiong (United States)

Jeremy Wong (United States)

Maxime Patout (France)

Laura Donahue (United States)

12:10am – 12:15am

Conclusion and next steps

Teofilo Lee-Chiong (United States)

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

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FRIDAY September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

S-18: iRBD biomarkers through the lens of young scientists: What do we have and what do we need?

10:45am – 12:15pm | Room 308

Chair: Bradley Boeve (United States)

10:45am – 10:47am

Introduction

10:47am – 11:03am

Clinical biomarkers in iRBD: Foundations for precision and integration

Luca Baldelli (Italy)

11:03am – 11:19am

Molecular and metabolic imaging biomarkers: What’s missing?

Beatrice Orso (Italy)

11:19am – 11:35am

Electrophysiology and digital biomarkers: Automated monitoring of progression and phenoconversion in iRBD

Matteo Cesari (Austria)

11:35am – 11:51am

Recent developments in diagnostic, prognostic, and disease-monitoring wet biomarkers in iRBD

Bei Huang (Hong Kong)

11:51am – 12:07pm

The ideal biomarker(s): From big data to personalized medicine

Bradley Boeve (United States)

12:07pm – 12:15pm

Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-19: Associations of accelerometryderived sleep variables with age-related disease outcomes and variations across sociodemographic groups and wearing time: Findings from the CHARGE Accelerometry Working Group

10:45am – 12:15pm | Room 309

Chair: Heming Wang (United States)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Actigraphy-derived sleep quality and MRI markers of dementia in a diverse cohort of older adults

Clémence Cavaillès (France)

11:07am – 11:27am

Associations of objectively measured sleep restriction-rebound patterns with all-cause mortality

Xiaoyu Li (China)

11:27am – 11:47am

Reliability of brief accelerometer-based sleep measurements for capturing long-term sleep duration and variability

Heming Wang (United States)

11:47am – 12:07pm

Association between accelerometry derived sleep duration with CVD and mortality

Kaitlin Potts (United States)

12:07pm – 12:15pm

Question and Answer

FRIDAY September 5, 2025

Scientific Program | MONDAY

S-20: Exploring the intersections of sleep bruxism, orofacial pain, insomnia, and obstructive sleep apnea

10:45am – 12:15pm | Room 324

Chairs: Ghizlane Aarab (Netherlands), Peter Svensson (Singapore)

10:45am – 10:47am

Introduction

10:47am – 11:03am

Introduction of the Intersections of Sleep Bruxism, Orofacial Pain, Insomnia, and Obstructive Sleep Apnea

Ghizlane Aarab (Netherlands)

11:03am – 11:19am

Overview of the mosaic of risk factors connecting orofacial pain and muscle activity in sleep bruxism

Peter Svensson (Singapore)

11:19am – 11:35am

Exploring common risk factors linking sleep bruxism and insomnia

Thiprawee Chattrattrai (Thailand)

11:35am – 11:51am

Breaking the cycle: cognitive behavioral therapy for insomnia in patients with orofacial pain

Wendy Knibbe (Netherlands)

11:51am – 12:07pm

From Bruxing to Breathing: Exploring the Complex Relationship between Sleep Bruxism and Obstructive Sleep Apnea

Deshui Li (China)

12:07pm – 12:15pm

Question and Answer

WEDNESDAY September 10, 2025

S-21: Current evidence on cardiometabolic diseases and sleep disorders; Asian Perspectives

10:45am – 12:15pm | Room 325

Chairs: Yuichi Inoue (Japan), Naricha Chirakalwasan (Thailand)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Association between the incidence of major adverse cardiovascular events and the presence of obstructive sleep apnea

Ronald Lee (Singapore)

11:07am – 11:27am

The relationship between sleep duration and glucose metabolism

Sirimon Reutrakul (United States)

11:27am – 11:47am

The prevalence of insomnia in Asia and its association with the increased risks of cardiometabolic diseases

Naricha Chirakalwasan (Thailand)

11:47am – 12:07pm

The effect of environmental components in shaping sleep quality and duration

Motoo Yamauchi (Japan)

12:07pm – 12:15pm

Question and Answer

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

SCAN TO DOWNLOAD THE WORLD SLEEP 2025 APP! Supported by

FRIDAY

September 5, 2025 SATURDAY September 6, 2025

September 7, 2025 MONDAY September 8, 2025 TUESDAY September 9, 2025

Scientific Program | MONDAY

S-22: Patterns of plates and pillows: Exploring the bidirectional interplay between sleep and circadian rhythms, and eating behavior and metabolic outcomes

10:45am – 12:15pm | Room 326

Chairs: Morgan H James (Australia), Joel S Raymond (United States)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Eat, sleep, two-way street? Unravelling the reciprocal dynamics between sleep and eating using preclinical animal models

Joel S Raymond (United States)

11:07am – 11:27am

From plate to pillow: How eating behaviours and sleep influence each other

Marie-Pierre St-Onge (United States)

11:27am – 11:47am

The effect of circadian disruption on eating behaviour, dietary intake, and metabolic outcomes in night shift working populations

Maxine Bonham (Australia)

11:47am – 12:07pm

Chrononutrition as a shared determinant of poor sleep and obesity in adolescents: Insights from the Teen Sleep Well Study

Emma Louise Gale (United Kingdom)

12:07pm – 12:15pm

Question and Answer

WEDNESDAY September 10, 2025

O-05: Optimizing therapeutic strategies and outcomes in obstructive sleep apnea management

10:45am – 12:15pm | Room 327

Chair: Raphael Heinzer (Switzerland), Maree Barnes (Australia)

10:45am – 10:58am

Benefits of Early Body Weight Reduction in Participants with Obesity and Moderate-to-severe Obstructive Sleep Apnea: A Post Hoc Analysis of SURMOUNT-OSA

Ying Ni Lin (China)

10:58am – 11:11am

The Effect of Zolpidem on CPAP Acclimatization in Patients with OSA: A Crossover, Randomized, Double-blinded, Placebo-controlled Trial

Piyakorn Pisalnoradej (Thailand)

11:11am – 11:24am

The Effect of Telemedicine-Based CPAP Management on 24-Hour Ambulatory Blood Pressure in Patients with Obstructive Sleep Apnea: A Randomized, Controlled, Non-Inferiority Trial huijie Yi (China)

11:24am – 11:37am

CPAP, Mortality & Life Expectancy in Obstructive Sleep Apnea: A Patient-Level Meta-Analysis of Reconstructed Survival Data

Nicole Kye Wen Tan (Singapore)

11:37am – 11:50am

Real-World Evidence for Surgical and Nonsurgical Sleep Apnea Therapies: safety, Clinical Outcomes and Healthcare Utilization Patterns

Robson Capasso (United States)

11:50am – 12:03pm

Five-year, prospective, multicenter, real-world study to assess initial delivery, management and longterm effectiveness of a CAD/CAM, 3-D printed oral appliance in the treatment of obstructive sleep apnea: Interim Analysis Update

Robyn Woidtke (United States)

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

O-06: Innovations in the diagnosis and management of RLS

10:45am – 12:15pm | Room 328

Chairs: Elias Karroum (United States), Maria Paola Mogavero (Italy)

10:45am – 10:58am

Efficacy of transcutaneous spinal direct current stimulation and pneumatic compression in restless legs syndrome and augmentation

Nikita Gorbachev (Russian Federation)

10:58am – 11:11am

Tonic motor activation therapy in patients with painful versus painless restless legs: An interim 180day results from the THRIVE study

Elias Karroum (United States)

11:11am – 11:24am

Clinical Characteristics, Polysomnography, and Iron Metabolism in Restless Legs Syndrome Patients with Obstructive Sleep Apnea: A Comparative and Cluster Analysis Study

Yanyan Hou (China)

11:24am – 11:37am

Clinical influence of restless legs syndrome in migraine patients: a 12-year single-center longitudinal study

Keisuke Suzuki (Japan)

11:37am – 11:50am Impact of Dopamine Agonists and Clonazepam on LMM and PLMS in RLS Patients

Maria Paola Mogavero (Italy), Raffaele Ferri (Italy)

11:50am – 12:03pm

Neurological approaches to restless legs syndrome: a systematic review of non-pharmacological interventions

Joao Victor Pereira Gonzalez (Brazil)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-07: Dental and surgical sleep medicine interactions

10:45am – 12:15pm | Room 329

Chairs: Cibele Dal Fabbro (Canada), Susana Falardo (Portugal)

10:45am – 10:58am

Ultrasound-Guided Tongue Base Thickness as a Screening Tool for Assessing Severity among patients with symptoms of Obstructive Sleep Apnea (OSA) at the Lung Center of the Philippines

Mark Edison De Vera (Philippines)

10:58am – 11:11am

Analysis of Chest and Abdominal Respiratory Movements Prior to Masticatory Muscle Activity

During Sleep

Kento Hata (Japan)

11:11am – 11:24am

Sleep quality and daytime sleepiness is related to immune and comorbidity status in temporomandibular disorders

Ji Woon Park (Korea, Republic of)

11:24am – 11:37am

Effect of orofacial myofunctional therapy (OMT) on chewing efficiency, lip strength and tongue strength in participants of the “OMT with autofeedback for obstructive apnea” (OMTAOSA) randomized controlled trial

Unn Tinbod (Norway)

11:37am – 11:50am

Impact of High Mandibular Plane on Surgical Outcomes of Maxillomandibular Advancement for Obstructive Sleep Apnea

Fang-Yu Hsu (Taiwan)

11:50am – 12:03pm

Minimal titration approach for mandibular advancement device treatment in patients with obstructive sleep apnea: a retrospective multicenter observational cohort study

Marc Braem (Belgium)

FRIDAY September 5, 2025

SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

O-08: Light and sleep health

10:45am – 12:15pm | Room 330

Chairs: Xiao Tan (Sweden), Leon Lack (Australia)

10:45am – 10:55am

Examining the impact of seasonal variations in photoperiod on sleep in young adults

Saranea Ganesan (United Kingdom)

10:55am – 11:05am

Light Exposure Patterns and Human Health: Insights from Large-Scale Personal Light Tracking

Sean Cain (Australia)

11:05am – 11:15am

Diurnal light exposure and circadian rest-activity rhythms with the risk of metabolic dysfunctionassociated fatty liver disease

Xiao Tan (Sweden)

11:15am – 11:25am

Light at Night Exacerbates Depression Risk via Circadian Disruption and Hippocampal Per1

Dysregulation: Translational Evidence from a Largescale Prospective Cohort and Animal Study

Hongliang Feng (China)

11:25am – 11:35am

Use of Apple Watch to Optimize Light Therapy and Reduce Circadian Misalignment for Night Shift Workers

Marleigh Treger (United States)

11:35am – 11:45am

Blue light influences loss aversion

Alicia Lander (Australia)

Intercultural Compilation of Physiological and Oneiric Sleep

11:00am – 12:00pm | Room 311

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

New directions in measuring sleep outside the lab

12:20pm – 1:15pm | Room 302

Chairs: Merve Aktan Süzgün (Türkiye), Yamei Li (China)

Resmed: OSA Underdiagnosis- A world of difference, a common challenge

12:45pm – 1:45pm | Hall 406 C

Chair: Erna Sif Arnardóttir (Iceland)

12:45pm – 12:55pm

Lecture: The Diagnosis Crisis

Erna Sif Arnardóttir (Iceland)

12:45pm – 1:35pm

Panel discussion: Global perspectives - What’s working and what’s not in OSA diagnosis -Charting the Path Forward

Erna Sif Arnardóttir (Iceland)

Michelle Zeidler (United States)

Ronald Lee (Singapore)

Ludger Grote (Sweden)

1:35pm – 1:45pm

Wrapup and next steps

Erna Sif Arnardóttir (Iceland)

CME/EBAC-accredited - Breaking the Cycle: Prioritizing Weight Loss to Improve OSA Management

12:45pm – 1:45pm | Nicoll 1

Supported by an educational grant from Lilly.

FRIDAY

September 5, 2025

SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

Bayer: Sleep disturbance across menopause –innovations in measurement and treatment

12:45pm – 1:45pm | Room 303

Chair: Fiona C. Baker (United States)

12:45pm – 12:50pm

Welcome and Introduction

Fiona C. Baker (United States)

12:50pm – 1:00pm

Menopause and sleep: Why it matters, How it happens

Rossella E. Nappi (Italy)

1:00pm – 1:15pm

Measuring sleep in menopause: moving from the lab to the Real World

Fiona C. Baker (United States)

1:15pm – 1:30pm

Dual neurokinin-targeted therapy and beyond:

Mechanisms and guidelines

Claudio N. Soares (Canada)

1:30pm – 1:40pm

Panel discussion and Q&A

1:40pm – 1:45pm

Closing remarks and key takeaways

Fiona C. Baker (United States)

Eisai: RISE – Regional Insights in Sleep Excellence

12:45pm – 1:45pm | Room 309

Chair: Roger C.M. Ho (Singapore)

12:45pm – 1:10pm

Evolving National Guidelines: The 2025 Thailand/Thai Framework for Insomnia Management

Puntarik Srisawart (Thailand)

1:10pm – 1:45pm

Real-World Use of Lemborexant in Japan: Insights from the SELENADE Study

Yoshikazu Takaesu (Japan)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

Asleep: Challenging Consumer Sleep-Tracker Limits: From Mobile Innovation to Data-Driven Sleep Care

12:45pm – 1:45pm | Room 324

12:45pm – 12:48pm

Redefining sleep-tracker standards: A new era of sleep measurement with mobile AI

David Lee (Korea, Republic of)

12:48pm – 12:56pm

Medical evaluation of sleep trackers and the smartphone-based approach ensuring accuracy for clinical use

Clete Kushida (United States)

12:56pm – 1:04pm

Challenges and innovations in pediatric sleep monitoring: Accurate and contactless sound-based AI analysis

Yusam Jung (Korea, Republic of)

1:04pm – 1:12pm

Extending AI sleep measurement: Postures, arousals, and oxygen saturation: A multi-dimensional sleep analysis

In-Young Yoon (Korea, Republic of)

1:12pm – 1:20pm

Sleep-data utilization: From statistical insights to environmental control: Integrating macro-level data analysis with micro-level environmental control (‘Hey Sleep’)

Ki-Young Jung (Korea, Republic of)

1:20pm – 1:28pm

Expanding surgical treatment with AI sleep monitoring: Pre- and post-operative applications of sleep data

Stanley Liu (United States)

1:28pm – 1:33pm

Track-agent-action: The framework for universal sleep tracking: Real-world implementations and sleep-tech innovations

David Lee (Korea, Republic of)

1:33pm – 1:35pm

Question and answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

ProSomnus: Beyond Mandibular Advancement: Science, Innovation and Outcomes

12:45pm – 1:45pm | Room 326

Stepwise Add-On and Endotype-informed Targeted Combination Therapy to Treat OSA

Danny Eckert (Australia)

Effectiveness of Oral Appliance Therapy as First-Line Treatment Compared with CPAP: The FLOSAT Study

Olivier Vanderveken (Belgium)

ProSomnus RPMO2 Oral Device with Embedded Oxygen Sensor

Edward Sall (United States)

Sefam: Predictive Markers of Cardiovascular Risk in Patients with OSA

1:45pm – 2:30pm | Room 302

Chair: Ronald Lee (Singapore)

Predictive Markers of Cardiovascular Risk in Patients with OSA

Takatoshi Kasai (Japan)

Sleep Science, Technology, and Economy Symposium - Golden Triangle

1:45pm – 4:45pm | Room 325

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

Philips SleepStudio: Advantages of automatic NIV (AVAPS-AE) in managing OHS

2:00pm – 2:45pm | Room 311

Chair: Leong-Chai Leow (Singapore)

Background and methodology of the Pickwick

Titration Randomized Clinical Trial

Babak Mokhlesi (United States)

Main results of the Pickwick Titration Randomized Clinical Trial

Juan Fernando Masa Jimenez (Spain)

AVAPS-AE Customized for Every Patient

Julie Yarascavitch (United States)

Panel Discussion

K-03: Tiina Paunio

Sleep and development: Exploring the impact of sleep on mental health in children

2:15pm – 3:00pm | Hall 406 C

2:15pm – 2:17pm Introduction

2:17pm – 3:00pm

Sleep and development: Exploring the impact of sleep on mental health in children

Tiina Paunio (Finland)

FRIDAY

September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

K-04: Hiroki R. Ueda

Towards human systems biology of sleep/wake cycles: The role of calcium and phosphorylation in sleep

2:15pm – 3:00pm | Hall 406 D

2:15pm – 2:17pm

Introduction

Shantha Rajaratnam (Australia)

2:17pm – 3:00pm

Towards human systems biology of sleep/wake cycles: The role of calcium and phosphorylation in sleep

Hiroki R. Ueda (Japan)

Philips SleepStudio: Optimizing peak-flowtriggered ASV to control both CSA and OSA in heart failure: tricks of the trade from ADVENT-HF

3:00pm – 3:45pm | Room 311

Chair: Julius Goh Liang Chye (Malaysia)

Optimizing peak-flow-triggered ASV to control both CSA and OSA in heart failure: tricks of the trade from ADVENT-HF

Douglas Bradley (Canada)

Setting personalized therapy targets with BiPAP autoSV

Julie Yarascavitch (United States)

Panel Discussion

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-23: Harnessing sensors and big data to decipher the link between sleep health and cardiovascular risk: Innovations and applications

3:15pm – 4:45pm | Hall 406 C

Chair: Alessandro Silvani (Italy)

3:15pm – 3:17pm

Introduction

3:17pm – 3:33pm

An Integrated Approach to Sleep-Cardiovascular Physiology: Utilizing Multi-Sensor and Multi-Device Data

Alessandro Silvani (Italy)

3:33pm – 3:49pm

Long-Term Monitoring of Sleep, Activity, and Heart Rate Using Multi-Sensor Wearables: Lessons from Narcolepsy Type One

Oriella Gnarra (Switzerland)

3:49pm – 4:05pm

Digital Phenotyping via Consumer Wearables to Identify Links Between Sleep, Cardiovascular Disease Risk and Biological Aging

Weng Khong Lim (Singapore)

4:05pm – 4:21pm

Leveraging Multi-Sensor Wearable Technology: Mapping Cardiorespiratory Health through PPG and Accelerometry

Pauli Ohukainen (Finland)

4:21pm – 4:37pm

Translating Sleep Sensor and Big Data into Cardiorespiratory Care: Clinical Implications and Opportunities

Cathy Goldstein (United States)

4:37pm – 4:45pm

Question and Answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

S-24: Novel approaches to address sleep problems in young children: Evidence from 5 randomized controlled trials

3:15pm – 4:45pm | Hall 406 D

Chair: Michal Kahn (Israel)

3:15pm – 3:17pm Introduction

3:17pm – 3:33pm

Preventing postpartum insomnia: A three-arm RCT of CBT-I, responsive bassinets, and sleep hygiene

Meagan Crowther (Australia)

3:33pm – 3:49pm

Promoting infant sleep through enhanced coparenting: Results from a sleep-adapted family foundations intervention

Douglas Teti (United States)

3:49pm – 4:05pm

The “bedtime checking” sleep intervention in infants with insomnia: Preliminary results

Liat Tikotzky (Israel)

4:05pm – 4:21pm

Addressing parental cognitions to improve infant insomnia: Results from a randomized controlled trial

Sooyeon(Aly) Suh (Korea, Republic of)

4:21pm – 4:37pm

Enhancing imagery rehearsal therapy with the DreamChanger: A novel approach for treating nightmares in children

Michal Kahn (Israel)

4:37pm – 4:45pm

Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-25: Open data and open science in sleep medicine and sleep research

3:15pm – 4:45pm | Nicoll 1

Chairs: Thomas Penzel (Germany), Diane Lim (United States)

3:15pm – 3:17pm

Introduction

3:17pm – 3:37pm

Open science in sleep research in Europe: Legal limits, new opportunities and recent progress

Dagmar Krefting (Germany)

3:37pm – 3:57pm

Benefits and challenges of open science: A neuro-AI perspective

Thomas Yeo (Singapore)

3:57pm – 4:17pm

The National Sleep Resource enables phenotype research and personalized medicine

Shaun Purcell (United States)

4:17pm – 4:37pm

Interoperability, integration and harmonization of data from multiple sources for sleep medicine

Christoph Schoebel (Germany), Cynthia Schmidt (Germany)

4:37pm – 4:45pm

Question and answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

S-26: Advancing biomarkers in isolated REM sleep behavior disorder: Pathways to clinical implementation

3:15pm – 4:45pm | Nicoll 2

Chair: Shady Rahayel (Canada)

3:15pm – 3:17pm Introduction

3:17pm – 3:33pm

Leveraging structural MRI and neurocomputational models to predict disease pathways in iRBD

Shady Rahayel (Canada)

3:33pm – 3:49pm

Brain molecular imaging for predicting phenoconversion and monitoring disease progression in iRBD

Giulia Carli (United States)

3:49pm – 4:05pm

EEG and sleep structure features as disease progression biomarkers in iRBD

Andreas Brink-Kjaer (Denmark)

4:05pm – 4:21pm

Structural connectivity alterations and network reorganisation in iRBD

Christina Tremblay (Canada)

4:21pm – 4:37pm

Quantitative brain iron changes and genetic risk factors in iRBD

Rahul Gaurav (France)

4:37pm – 4:45pm Question and Answer

MONDAY September 8, 2025 TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-27: Symptom subtypes of obstructive sleep apnea: Past, present, and future

3:15pm – 4:45pm | Nicoll 3

Chairs: Peter Cistulli (Australia), Allan Pack (United States)

3:15pm – 3:17pm

Introduction

3:17pm – 3:37pm

The current status of symptom subtypes – An international perspective

Brendan Keenan (United States)

3:37pm – 3:57pm

Are men and women really the same when it comes to OSA symptoms subtypes?

Maria Bonsignore (Italy)

3:57pm – 4:17pm

An ‘omics approach to predict the excessively sleepy OSA subtype

Yun Li (China)

4:17pm – 4:37pm

Translating symptoms subtypes to the clinic –What are the next steps?

Ulysses Magalang (United States)

4:37pm – 4:45pm Question and Answer

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FRIDAY

September 5, 2025

SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

S-28: Global insights and emerging perspectives on sleep (ir)regularity

3:15pm – 4:45pm | Room 303

Chairs: Andrew Phillips (Australia), Amy Reynolds (Australia)

3:15pm – 3:17pm Introduction

3:17pm – 3:37pm

Measuring sleep (ir)regularity : Current metrics and applications

Dorothee Steven (Germany)

3:37pm – 3:57pm

Linking sleep irregularity to cardiometabolic disease and mortality: Epidemiologic evidence

Andrew Phillips (Australia)

3:57pm – 4:17pm

Multigenerational sleep regularity and its associations with physical and mental health

Amy Reynolds (Australia)

4:17pm – 4:37pm

The comparative role of sleep regularity and sleep duration for risk of chronic health outcomes

Daniel Windred (Australia)

4:37pm – 4:45pm Question and Answer

CAP Taskforce Discussion Session: Implementing the Updated ESRS Scoring Rules and Atlas

3:15pm – 4:45pm | Room 306

3:15pm – 4:45pm Taskforce Members and Contributors

Heiður Grétarsdóttir (Iceland), Liborio Parrino (Italy), Robert Thomas (United States), Ivana Rosenzweig (United Kingdom), Oliviero Bruni (Italy), Gulcin Benbir Senel (Türkiye), Erna Sif Arnardóttir (Iceland), Raffaele Ferri (Italy)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-29: ISSS symposium: Neurostimulation in the treatment obstructive sleep apnea: Current understanding, challenges and the future

3:15pm – 4:45pm | Room 308

Chairs: Song Tar Toh (Singapore), Maria Suurna (United States)

3:15pm – 3:17pm

Introduction

3:17pm – 3:33pm

What is the current landscape in neurostimulation for OSA - who, why, where, when and what is being done?

Clemens Heiser (Germany)

3:33pm – 3:49pm

What is the current evidence to support neurostimulation in OSA?

Ofer Jacobowitz (United States)

3:49pm – 4:05pm Challenges in implementing neurostimulation in my country? Financial and regulatory considerations

Shaun Loh (Singapore)

4:05pm – 4:21pm Future directions in neurostimulation

David Kent (United States)

4:21pm – 4:37pm

Debate / Discussion: Will neurostimulation become first line treatment in OSA

4:37pm – 4:45pm Question and Answer

FRIDAY September 5, 2025

SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

S-30: New insights and opportunities into sleep and pregnancy health with wearable big data and digital health interventions

3:15pm – 4:45pm | Room 324

Chairs: Massimiliano de Zambotti (United States), Laura Palagini (Italy)

3:15pm – 3:17pm Introduction

3:17pm – 3:37pm

The interaction of circadian rhythms, lifestyles, and behavior on maternal and offspring health

Ling-Wei Chen (Taiwan)

3:37pm – 3:57pm

Sleep disorders and mental health in pregnancy and postpartum: An overlooked critical factor in women’s health

Laura Palagini (Italy)

3:57pm – 4:17pm

Smart wearables to unlock new opportunities in monitoring sleep and pregnancy health

Massimiliano de Zambotti (United States)

4:17pm – 4:37pm

Integrating digital tools to improving perinatal sleep

Bei Bei (Australia)

4:37pm – 4:45pm

Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-09: Targeting the orexin pathway: Emerging pharmacotherapies for narcolepsy type 1

3:15pm – 4:46pm | Room 327

Chairs: Yuichi Inoue (Japan), Sheila Sivam (Australia)

3:15pm – 3:28pm

Vibrance-1: A Randomized Phase 2 Study Evaluating Safety and Efficacy of the Orexin 2 Receptor Agonist Alixorexton (ALKS 2680) in Patients with Narcolepsy Type 1

Giuseppe Plazzi (Italy)

3:28pm – 3:41pm

Improvement in the Severity of Narcolepsy Symptoms and Fatigue in Patients with Narcolepsy Type 1 Treated with the Orexin 2 Receptor Agonist Alixorexton (ALKS 2680)

Yves Dauvilliers (France)

3:41pm – 3:54pm

Improvement in Patient-reported Cognitive Functioning in Patients with Narcolepsy Type 1 Treated with the Orexin 2 Receptor Agonist Alixorexton (ALKS 2680)

Giuseppe Plazzi (Italy)

3:54pm – 4:07pm

The First Light: Efficacy and Safety of a multi-dose study of Oveporexton (TAK-861), an Oral Orexin Receptor 2 Agonist for the Treatment of Narcolepsy Type 1

Emmanuel Mignot (United States)

4:07pm – 4:20pm

The Radiant Light: Efficacy and Safety of Oveporexton (TAK-861), an Oral Orexin Receptor 2 Agonist for the Treatment of Narcolepsy Type 1

Yves Dauvilliers (France)

4:20pm – 4:33pm

Effect of Oral Orexin Receptor 2 Agonist Oveporexton (TAK-861) on the Severity of Symptoms in Individuals With Narcolepsy Type 1: Results From Two Phase 3 Studies

Lucie Barateau (France)

4:33pm – 4:46pm

Effect of the Oral Orexin Receptor 2 Agonist

Oveporexton (TAK-861) on Quality of Life in Individuals with NT1 over 12 weeks

Sheila Sivam (Australia)

FRIDAY

September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

O-10: Novel approaches to treating insomnia

3:15pm – 4:45pm | Room 328

3:15pm – 3:28pm

Mindfulness-imbued insomnia therapy enhances antidepressant outcomes for pregnant women with insomnia and depression: A comparative effectiveness randomized controlled trial of CBTI and PUMAS

Heba Afaneh (United States)

3:28pm – 3:41pm

Intensive Sleep Retraining and Total Sleep Deprivation for Treating Chronic Insomnia: A Randomised Controlled Trial

Charles Morin (Canada)

3:41pm – 3:54pm

Effect of combined treatment with transcranial direct current stimulation and repetitive transcranial magnetic stimulation compared to monotherapy for the treatment of chronic insomnia: a randomised, double-blind, parallel-group, controlled trial

Qi Zhou (China)

3:54pm – 4:07pm

Brain Network Study of Transcranial Plasma Therapy for Chronic Insomnia

Qinying Ma (China)

4:07pm – 4:20pm

Novel Approach for Biologically-Guided Therapeutics in Insomnia

Carolina Gutierrez Herrera (Switzerland)

4:20pm – 4:33pm

Effects of Music Presentation on Sleep Quality and Functional Connectivity in the Brain Estimated using EEG

Hiroto Irimajiri (Japan)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-11: Sleep in childhood and adolescence

3:15pm – 4:45pm | Room 329

Chair: Mary Carskadon (United States), Albert Li (China)

3:15pm – 3:28pm

Autism, Sleep, and Medicinal Cannabis: Evaluating 18-Month Efficacy and Safety Outcomes

Mohsin Maqbool (United States)

3:28pm – 3:41pm

Integrated metagenomic and metabolomic analysis reveal distinctive gut microbiota-derived metabolites in pediatric obstructive sleep apnea

Xiaoman Zhang (China)

3:41pm – 3:54pm

Achieving recommended sleep duration and abdominal fat deposition: a sex-specific relationship in 10-year-old children

Shirong Cai (Singapore)

3:54pm – 4:07pm

Can sleep spindle characteristics distinguish children with narcolepsy from those with idiopathic hypersomnia and subjective sleepiness?

Rosemary Horne (Australia)

4:07pm – 4:20pm

The temporal associations between sleep and circadian preference, and mental health among Norwegian adolescents

Ingvild West Saxvig (Norway)

4:20pm – 4:33pm

Beyond the recommendations: A bioecological analysis of pre-bedtime screen use, moderate-to-vigorous physical activity and food intake in family contexts

Chao Gu (New Zealand)

FRIDAY

September 5, 2025

SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

O-12: Basic research: Animal models of sleep and sleep disorder

3:15pm – 4:45pm | Room 330

Chair: Monica Andersen (Brazil)

3:15pm – 3:28pm

Acetate improves neurocognition in sleep-deprived male Wistar rats via modulation of xanthine oxidase/uric acid-driven oxidative stress and NFkBdependent inflammation, and caspase 3-mediated apoptosis

Roland Akhigbe (Nigeria)

3:28pm – 3:41pm

Dim light at night exacerbate Parkinson’s disease through circadian rhythm related pathways in mice

Biao Li (China)

3:41pm – 3:54

Neural Adaptations Across Daily Torpor and Sleep: Ultrastructural, Molecular, and Behavioural Changes in Djungarian Hamsters (Phodopus sungorus)

Xiao Zhou (United Kingdom)

3:54 – 4:07pm

Subcortical connectivity patterns during the introduction of NREMS and isoflurane-induced loss of responsiveness are partly different along the sleep/wake promoting pathway in mice

Thomas Fenzl (Germany)

4:07pm – 4:20pm

Reducing complement activation during sleep deprivation yields cognitive improvement by dexmedetomidine

Qian Zhai (China)

4:20pm – 4:33pm

Exercise improves sleep deprivation-induced cognitive impairment by upregulating brain-derived neurotrophic factor and restoring hippocampal synaptic plasticity

Yining Wen (China)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-31: Sleep and digital media myth-busting: What should the recommended guidelines be for children, adolescents and young adults?

5:00pm – 6:30pm | Hall 406 C

Chairs: Emma Louise Gale (United Kingdom), Serena Bauducco (Sweden)

5:00pm – 5:02pm

Introduction

5:02pm – 5:18pm

Impact of screens on sleep: An update on mechanisms, moderators and bi-directional links

Serena Bauducco (Sweden)

5:18pm – 5:34pm

Using objective measures to determine if screens really do impact teen sleep

Rachael Taylor (New Zealand)

5:34pm – 5:50pm

Using passive sensing of screen time to improve assessment of timing and content effects on sleep health

Lauren Hale (United States)

5:50pm – 6:06pm

Personalized sleep interventions for young adults: Addressing bedtime postponement through a behavioral framework for media use

Sooyeon (Aly) Suh (Korea, Republic of)

6:06pm – 6:22pm

Feasibility of implementing global screen time changes to improve sleep health and physical and mental wellbeing in children and adolescents

Emma Louise Gale (United Kingdom)

6:22pm – 6:30pm

Question and Answer

FRIDAY

September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025 MONDAY September 8, 2025 TUESDAY September 9, 2025 WEDNESDAY September 10, 2025

Scientific Program | MONDAY

S-32: Sleep, sleep disorders and neurodegenerative diseases: Novel insights on mechanisms and interventions

5:00pm – 6:30pm | Hall 406 D

Chairs: Thien Thanh Dang-Vu (Canada), Géraldine Rauchs (France)

5:00pm – 5:02pm Introduction

5:02pm – 5:22pm

Sleep microarchitecture, cognition and neurodegeneration

Thien Thanh Dang-Vu (Canada)

5:22pm – 5:42pm

Effects of a Lifestyle Intervention on Sleep and Circadian Rest-Activity Rhythms in Older Adults at Risk of Cognitive Decline

Katie Stone (United States)

5:42pm – 6:02pm

Impact of sleep-disordered breathing on brain health and cognition, and its potential modulation by lifestyle

Géraldine Rauchs (France)

6:02pm – 6:22pm

Relationship between sleep disturbance and dementia biomarkers in at ‘at-risk’ sample

Sharon Naismith (Australia)

6:22pm – 6:30pm

Question and Answer

S-33: Global sleep health in turbulent times: Effects of political instability on funding, advocacy and health services

5:00pm – 6:30pm | Nicoll 1

Chairs: Peter Eastwood (Australia), Phyllis C. Zee (United States)

5:00pm – 5:05pm Introduction

Phyllis C. Zee (United States)

5:05pm – 5:25pm

WSS Global Sleep Health Taskforce

Peter Eastwood (Australia)

5:25pm – 5:45pm

Geopolitics of sleep research

Phyllis Zee (United States)

5:45pm – 6:05pm

Geopolitics of sleep health

Dayna Johnson (United States)

6:05pm – 6:25pm

Geopolitics of global healthA Singapore perspective Alex Cook (Singapore)

6:25pm – 6:30pm Question and Answer

FRIDAY

September 5, 2025

Scientific Program | MONDAY

S-34: Discussion group: Artificial intelligence in sleep medicine: The good, the bad, the ugly

5:00pm – 6:30pm | Nicoll 2

Chair: Qurratul (Afifa) Shamim-Uzzaman (United States)

5:00pm – 5:02pm

Introduction

5:02pm – 5:18pm

The Role of AI in the Future of Sleep Medicine

Jean-Louis Pépin (France)

5:18pm – 5:34pm

Perks & Pitfalls of Using AI in Scientific Writing

Ahmed BaHammam (Saudi Arabia)

5:34pm – 5:50pm

Resource Needs and Implementation Challenges of AI

Arash Maghsoudi (United States)

5:50pm – 6:06pm

Big Data and Machine Learning

Amir Sharafkhaneh (United States)

6:06pm – 6:22pm

Legal & Ethical Considerations of AI

Haitham Jahrami (Bahrain)

6:22pm – 6:30pm

Question and Answer

S-35: Sleep-Immune interactions and the role of sleep in Long COVID

5:00pm – 6:30pm | Nicoll 3

Chairs: Janet Mullington (United States), Estefania Martinez Albert (Germany)

5:00pm – 5:16pm

Introduction

Janet Mullington (United States)

5:16pm – 5:32pm

T-cell subsets involved in initiation and maintenance of adaptive immunity are facilitated in their migration to lymph nodes, by sleep

Estefania Martinez Albert (Germany)

5:32pm – 5:48pm

Vaccination, sleep and the risk for development of long COVID

Aric A Prather (United States)

5:48pm – 6:04pm

Sleep disorders as a risk factor for Long COVID with prominent cognitive sequelae

Claudia Schilling (Germany)

6:04pm – 6:20pm

Long COVID and immune factors modulated by sleep and recovery

Monika Haack (United States)

6:20pm – 6:30pm Question and Answer

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

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FRIDAY September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

S-36: Discussion group: Cannabis for the treatment of sleep disorders: What’s the POTential?

5:00pm – 6:30pm | Room 303

Chairs: Ron Grunstein (Australia), Paul Muchowski (United States)

5:00pm – 5:02pm Introduction

5:02pm – 5:22pm

Medicinal cannabis global landscape

Camilla Hoyos (Australia)

5:22pm – 5:42pm

Evidence for cannabinoid use for the treatment of poor sleep and insomnia

Jen Walsh (Australia)

5:42pm – 6:02pm

Evidence for cannabinoid use for the treatment of OSA, RBD, RLS & nightmare disorder

Alan Eckeli (Brazil)

6:02pm – 6:22pm

Medicinal cannabis prescribing practicalities from a clinician’s perspective

Simon Erridge (United Kingdom)

6:22pm – 6:30pm

Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-37: Social and neuropsychological outcomes in central disorders of hypersomnolence

5:00pm – 6:30pm | Room 308

Chairs: Yaroslav Winter (Germany), Anne Marie Morse (United States)

5:00pm – 5:02pm

Introduction

5:02pm – 5:18pm

Work productivity in patients with central disorders of hypersomnolence

Yuichi Inoue (Japan)

5:18pm – 5:34pm

Brain fog in central disorders of hypersomnolence

Anne Marie Morse (United States)

5:34pm – 5:50pm

The role of social outcomes from patient perspective

Stephanie Manuli (United States)

5:50pm – 6:06pm

Influence of psychiatric co-morbidity on social and neurocognitive outcomes in central disorders of hypersomnolence

Haykuhi Hovakimyan (Armenia)

6:06pm – 6:22pm

Cognitive impairment in central disorders of hypersomnolence and ways to treat it

Yaroslav Winter (Germany)

6:22pm – 6:30pm

Question and Answer

FRIDAY

September 5, 2025 SATURDAY September 6, 2025

September 7, 2025 MONDAY September 8, 2025

Scientific Program | MONDAY

S-38: New circuits underlying REM sleep regulation and homoeostasis

5:00pm – 6:30pm | Room 309

Chairs: Luis de Lecea (United States), Pierre-Herve Luppi (France)

5:00pm – 5:02pm

Introduction

5:02pm – 5:18pm

Neurobiology of paradoxical sleep

Pierre-Herve Luppi (France)

5:18pm – 5:34pm

REM-off neurons in the sublaterodorsal tegmentum (SLD) predict the onset of REM sleep

Luis de Lecea (United States)

5:34pm – 5:50pm

New markers of REM-on neurons in the sublaterodorsal tegmenjtum (SLD) sufficient to induce REM sleep

Yu Hayashi (Japan)

5:50pm – 6:06pm

Infraslow oscillation gates REM sleep

Anita Luthi (Switzerland)

6:06pm – 6:22pm

Identifying makers of ultradian REM sleep timing in EEG and EMG data

Franz Weber (United States)

6:22pm – 6:30pm

Question and Answer

September 9, 2025

WEDNESDAY September 10, 2025

S-39: Sleep well, feel well: Enhancing mental health across the lifespan through sleep interventions

5:00pm – 6:30pm | Room 324

Chairs: Cele Richardson (Australia), Christin Lang (Switzerland)

5:00pm – 5:02pm Introduction

5:02pm – 5:22pm

Expanding Sleep Ninja®: Findings from the adolescent trial and new adaptations for schools and younger audiences

Kate Maston (Australia)

5:22pm – 5:42pm

SLEEPAC: Findings from a transdiagnostic multicomponent sleep intervention to improve sleep & psychopathology in adolescent psychiatric outpatients

Christin Lang (Switzerland)

5:42pm – 6:02pm

Preliminary findings from a trial evaluating Digital Cognitive Behavioural Therapy for Insomnia on Depression Symptoms and Processes in Young Adults

Cele Richardson (Australia)

6:02pm – 6:22pm

Preliminary findings from a pragmatic, randomized controlled trial of group cognitive behavioural therapy for insomnia in psychiatric care

Ane Wilhelmsen-Langeland (Norway)

6:22pm – 6:30pm

Question and Answer

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

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FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

S-40: Best of SLEEP MEDICINE –

Journal Highlights 2025

5:00pm – 6:30pm | Room 325

Chairs: Winfried Randerath (Germany), Oliviero Bruni (Italy)

5:00pm – 5:02pm Introduction

5:02pm – 5:18pm

Sleep disordered breathing

Robert Thomas (United States)

5:18pm – 5:34pm

Insomnia and parasomnia

Eunyeon Joo (Korea, Republic of)

5:34pm – 5:50pm Movement disorders

Garima Shukla (Canada)

5:50pm – 6:06pm

Sleep and neurological disorders

Luigi Ferini-Strambi (Italy)

6:06pm – 6:22pm

Pediatric sleep medicine

Oliviero Bruni (Italy)

6:22pm – 6:30pm Question and Answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-41: To wake up or continue sleep: Arousal dynamics and sleep stability in health and disease

5:00pm – 6:30pm | Room 326

Chairs: Rick Wassing (Australia), Alejandro Osorio-Forero (Colombia)

5:00pm – 5:02pm Introduction

5:02pm – 5:22pm

Intrusion of wake-like activity in sleep and relationship with sleep disorders

Aurelie Stephan (France)

5:22pm – 5:42pm

Do micro-arousals contribute to the restorative property of sleep?

Natalie Hauglund (Denmark)

5:42pm – 6:02pm

Bridging developmental and clinical perspectives: The Infraslow fluctuation of sigma power in sleep

Maria Dimitriades (Greece)

6:02pm – 6:22pm

To wake or continue sleep: Arousal characteristics in adults with insomnia disorder treated with cannabinoids and placebo

Rick Wassing (Australia)

6:22pm – 6:30pm Question and Answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | MONDAY

O-13: New sensing or signal analysis methods in sleep

5:00pm – 6:30pm | Room 327

Chairs: Gizem Yilmaz (Singapore), Mathias Baumert (Australia)

5:00pm – 5:13pm

Contactless Oxygen Desaturation Prediction and ODI

Estimation from Nocturnal Breathing Sounds via Deep Learning

EunSung Cho (Korea, Republic of)

5:13pm – 5:26pm

Beyond Conventional Sleep: Modelling Diverse Sleep Behaviours Using Personalized Sleep Probability

Chun Siong Soon (Singapore)

5:26pm – 5:39pm

The Effect of Different Auditory Stimulation Modalities on Sleep Slow Wave Activity and Cognitive Performance

Christopher Jones (United States)

5:39pm – 5:52pm

Silicon Nanowire Field-Effect Transistor Biosensors for the Detection of Melatonin as Sleep Disorder Biomarker

Tianlang Ou (China)

5:52pm – 6:05pm

Hemodynamic spectral signatures across vigilance states: a whole-night EEG/fNIRS investigation

Shahla Bakian Dogaheh (Canada)

6:05pm – 6:18pm

Identifying and Predicting Emotionally Relevant

Adenosine-Mediated Sleep Enhancement via Transcranial Near-Infrared Photobiomodulation: Translational Evidence from Animal and Human Studies

Tae Kim (Korea, Republic of)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-14: Sleep and circadian regulation of cognition and memory

5:00pm – 6:30pm | Room 328

Chairs: June Lo (Singapore), Josheph De Koninck (Canada)

5:00pm – 5:13pm

Targeted memory reactivation during slow-wave sleep prompts systems-level changes in the neural basis of episodic memory

Scott Cairney (United Kingdom)

5:13pm – 5:26pm

Investigating the effects of REM sleep fragmentation on emotional memory and psychophysiological reactivity

Lorenzo Viselli (Italy)

5:26pm – 5:39pm

Dementia prediction tool based on accelerometry measures of circadian rhythm in older adults

Clémence Cavaillès (France)

5:39pm – 5:52pm

Associations between REM OSA, White Matter

Microstructure, and Cognition in Community-Dwelling Cognitively Unimpaired Older Adults

Joshua Gills (United States)

5:52pm – 6:05pm

Long sleep is associated with poor global cognitive function across diverse populations

Tamar Sofer (United States)

6:05pm – 6:18pm

Reward processing and eveningness in adolescents: A case-control study with EEG investigation

Fiona Yujing Jin (Hong Kong)

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

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FRIDAY September 5, 2025

SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | MONDAY

O-15: Psychiatric disorders affecting wake / sleep

5:00pm – 6:30pm | Room 329

Chairs: Joey Chan (Hong Kong), Daniel Buysse (United States)

5:00pm – 5:13pm

Impact of insomnia symptoms on the clinical outcomes among patients with major depressive disorder and eveningness – results from a randomized controlled trial

Joey Chan (Hong Kong)

5:13pm – 5:26pm

Sleep and Subsequent Mental Disorders in Young Adults: A National Prospective Diagnostic Study

Børge Sivertsen (Norway)

5:26pm – 5:39pm

A PVTD2R-CeA circuit underlies sleep disturbance and negative effects induced by morphine withdrawal

Wenjun Chen (China)

5:39pm – 5:52pm

Effects of a Dual Orexin-receptor Antagonist on Sleep Architecture and Opioid Withdrawal Severity during a Buprenorphine Taper

Andrew Huhn (United States)

5:52pm – 6:05pm

Sleep Profiles in Schizophrenia Inpatients: A CrossSectional Study of Clinical and Genetic Associations

Kseniia Gasenko (Russian Federation)

6:05pm – 6:18pm

Pre-Infusion EEG Vigilance Dynamics as Predictive Indicators of Ketamine Response in Major Depression: A Placebo-Controlled Study

Martin Brunovsky (Czech Republic)

6:18pm – 6:31pm

Sleep and PTSD Symptom Severity in Military Personnel: Insights from Multi-Night Ecological Recordings

Emeric Saguin (France)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-16: Sleep and aging brains: Patterns, risks, and predictive insights

5:00pm – 6:30pm | Room 330

Chairs: Bradley Boeve (United States), Anastasia Suraev (Australia)

5:00pm – 5:13pm

Association between cyclic alternating pattern during sleep and incident dementia

Ying Zheng (China)

5:13pm – 5:26pm

Sleep and longevity: insights from sleep macroarchitecture and nocturnal heart rate variabilty

Irina Filchenko (Switzerland)

5:26pm – 5:39pm

Obstructive sleep apnea physiological burdens and cognitive performance in older community dwelling American adults

Purbanka Pahari (United States)

5:39pm – 5:52pm

Poor subjective sleep quality independently predicts greater disability and functional decline in older adults at-risk of dementia

Anastasia Suraev (Australia)

5:52pm – 6:05pm

Identifying and Predicting Emotionally Relevant Sleep Disturbance Patterns in Dementia Family Caregivers: A Machine Learning Approach to Objective-Subjective Discrepancy

Tomoko Wakui (Japan)

6:05pm – 6:18pm

Associations of microarousals-related ventricular repolarization lability during sleep with long-term cardiovascular disease and mortality

Sizhi Ai (China)

Africa Sleep Network and Nigerian Sleep Society Meeting

5:30pm – 6:30pm | Room 306

Chair: Morenikeji Komolafe (Nigeria)

Poster abstract group 2

6:30pm – 7:30pm | Hall 405

Scientific Program | TUESDAY

World Sleep Society Membership Meeting

7:00am – 8:00am | Room 303

K-05: Lauren Hale

Social determinants and sleep health equity

8:00am – 8:45am| Hall 406 C

8:00am – 8:02am

Introduction

Yun Kwok Wing (Hong Kong)

8:02am – 8:45am

Social determinants and sleep health equity

Lauren Hale (United States)

K-06: Bei Bei

Behavioral sleep interventions in women across the lifespan

8:00am – 8:45am | Hall 406 D

8:00am – 8:02am

Introduction

Charles Morin (Canada)

8:02am – 8:45am

Behavioral sleep interventions in women across the lifespan

Bei Bei (Australia)

Exhibit Hall

8:30am – 3:30pm | Hall 405

S-42: Revolutionizing personalized medicine in OSA: Exploring new treatment modalities

9:00am – 10:30am | Hall 406 C

Chairs: Ding Zou (Sweden), Harald Hrubos-Strøm (Norway))

9:00am – 9:02am

Introduction

9:02am – 9:18am

Overview: From CPAP treatment to the first medicine for OSA patients with obesity

Ding Zou (Sweden)

9:18am – 9:34am

Kairos positive airway pressure (KPAP) for OSA treatment

William Noah (United States)

9:34am – 9:50am

Intra-Oral sensor systems for monitoring mandibular advancement device therapy

Peter Cistulli (Australia)

9:50am – 10:06am

Targeting upper airway muscle dysfunction in OSA: A new frontier in treatment

Ana Sanchez-Azofra (United States)

10:06am – 10:22am

Effect of orofacial myofunctional therapy with autofeedback in patients with newly diagnosed OSA: The OMTAOSA RCT

Diana Dobran Hansen (Norway)

10:22am – 10:30am

Question and answer

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

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FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

S-43: Insomnia Sub-typing: Pathophysiology, phenotypes and differential treatment response

9:00am – 10:30am | Hall 406 D

Chairs: Rachel Chan (Hong Kong), Jihui Zhang (China)

9:00am – 9:02am

Introduction

9:02am – 9:22am

Insomnia subtypes: Exploring links to demographic factors, mood problems, alcohol use and hypnotic medications

Bjørn Bjorvatn (Norway)

9:22am – 9:42am

Insomnia with objective short sleep duration: Pathophysiology, consequences and response to CBT-I

Julio Fernandez-Mendoza (United States)

9:42am – 10:02am

Digital multi-modal approaches for sub-typing insomnia disorder

Jihui Zhang (China)

10:02am – 10:22am

Sub-typing insomnia for predicting response towards cognitive behavioral therapy for insomnia

Rachel Chan (Hong Kong)

10:22am – 10:30am

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-44: Sleep and cardiometabolic health: Pathophysiology, and novel preventive and therapeutic strategies

9:00am – 10:30am | Nicoll 1

Chairs: Dalva Poyares (Brazil), Helga Margrét Skúladóttir (Iceland)

9:00am – 9:02am

Introduction

9:02am – 9:18am

Breathless nights, lifelong impact: Sleep-disordered breathing and cardiometabolic risk in pregnancy

Sushmita Pamidi (Canada)

9:18am – 9:34am

Insufficient sleep and vascular damage: Mechanisms and implications

Naima Covassin (United States)

9:34am – 9:50am

Narcolepsy and cardiometabolic health

Virend Somers (United States)

9:50am – 10:06am

Light, sleep and cardiometabolic disease –A Scandinavian perspective

Fjola D.H. Sigurdardottir (Norway)

10:06am – 10:22am

Healthy sleep: A game changer for weight loss

Esra Tasali (United States)

10:22am – 10:30am

Question and answer

FRIDAY

5,

Scientific Program | TUESDAY

S-45: The role of autovideosomnography in research: How AI and big data are transforming pediatric sleep and development research

9:00am – 10:30am | Nicoll 2

Chair: Oliviero Bruni (Italy)

9:00am – 9:02am

Introduction

9:02am – 9:18am

A cross-sectional study on the relationship between infant sleep, temperament, and bedtime practices

Maria Breda (Italy)

9:18am – 9:34am

Debunking the teething-sleep disruption myth: Insights from a longitudinal auto-videosomnography study

Michal Kahn (Israel)

9:34am – 9:50am

The impact of the transition to kindergarten on child sleep using autovideosomnography analysis

Ekjot Saini (United States)

9:50am – 10:06am

How does infant sleep relate to parental insomnia, depression, and emotional regulation? A network analysis using Autovideosomnography data.

Zepeng Gou (Australia)

10:06am – 10:22am

The kids are asleep! Parental bedtime procrastination and its impact on sleep health

Sungkyoung Shin (Korea, Republic of)

10:22am – 10:30am

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

S-46: How sleep shapes memory dynamics from the lens of reactivation: New insights and future directions

9:00am – 10:30am | Nicoll 3

Chairs: Xiaoqing Hu (Hong Kong), Eitan Schechtman (United States)

9:00am – 9:02am

Introduction

9:02am – 9:22am

Can we use reactivation to improve sleep quality?

Björn Rasch (Switzerland)

9:22am – 9:42am

Interpreting sleep activity through neural contrastive learning

Yunzhe Liu (China)

9:42am – 10:02am

Memory consolidation for interconnected memories during sleep

Eitan Schechtman (United States)

10:02am – 10:22am

Spindle refractory period shapes emotional memory reactivation

Tao Xia (Hong Kong)

10:22am – 10:30am

Question and answer

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

Supported by

SCAN TO DOWNLOAD THE WORLD SLEEP 2025 APP!

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

S-47: Beyond the lab: Measuring sleep and circadian rhythms in naturalistic settings

9:00am – 10:30am | Room 303

Chairs: Leila Tarokh (Switzerland), Mary Carskadon (United States)

9:00am – 9:02am

Introduction

9:02am – 9:22am

Circadian timing in American adolescents: Homebased assessments of dim light melatonin onset in major depressive disorder

Mary Carskadon (United States)

9:22am – 9:42am

Home-based insights into sleep neurophysiology and mental health in youth with and without major depressive disorder

Leila Tarokh (Switzerland)

9:42am – 10:02am

Rhythms of rest: Exploring sleep health and environmental influences on circadian rhythms in African youth

Karine Scheuermaier (South Africa)

10:02am – 10:22am

Beyond constant laboratory conditions: The role of environmental stimuli in the dynamic modulation of sleep expression

Markus Schmidt (Switzerland)

10:22am – 10:30am

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-48: Discussion group: Optimizing opioid therapy for restless legs syndrome /WillisEkbom disease: Insights from basic science to clinical practice

9:00am – 10:30am | Room 308

Chairs: Yuichi Inoue (Japan), John Winkelman (United States)

Discussants

Arthur Walters (United States), John Winkelman (United States), Yuichi Inoue (Japan), Ravi Gupta (India), Ambra Stefani (Austria)

S-49: New insights into the waking, sleeping and dreaming brain

9:00am – 10:30am | Room 309

Chairs: Elda Arrigoni (United States), Patrick Fuller (United States)

9:00am – 9:02am

Introduction

9:02am – 9:22am

Role of dopamine signaling in the amygdala in the regulation of REM sleep

Emi Hasegawa (Japan)

9:22am – 9:42am

The teleological mystery of sleep — Glioneuronal mechanisms integrating sleep homeostasis and motivation

Michael Lazarus (Japan)

9:42am – 10:02am

Long-range and local networks that regulate sleeppromoting ventrolateral preoptic neurons

Elda Arrigoni (United States)

10:02am – 10:22am

The intersection of sleep and stress circuity: How the brain drives hyperarousal in insomnia

Patrick Fuller (United States)

10:22am – 10:30am

Question and answer

FRIDAY

September 5, 2025

September 6, 2025

Scientific Program | TUESDAY

S-50: Bridging sleep research and practice: Leveraging implementation science to improve sleep equity around the globe

9:00am – 10:30am | Room 324

Chair: Suzanne Bertisch (United States)

9:00am – 9:02am

Introduction

9:02am – 9:18am

Preventing the voltage drop: Why implementation science matters

Suzanne Bertisch (United States)

9:18am – 9:34am

Implementation strategies (particularly technology and optimization) to improve adoption, implementation, and sustainment of best practices in health

Roman Xu (China)

9:34am – 9:50am

Addressing sleep apnea post-stroke: A hybrid type I cluster-randomized trial--results and lessons learned from the US veterans health administration

Jason Sico (United States)

9:50am – 10:06am

Sleep health challenges and opportunities: Focus on modifiable factors in African adults

Jesujoba Olanrewaju (Nigeria)

10:06am – 10:22am

Implementing the implementable - progress in dispensing good sleep health in Australian community pharmacies

Bandana Saini (Australia)

10:22am – 10:30am

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

September 7, 2025 WEDNESDAY September 10, 2025

S-51: The latest advances in understanding maternal sleep as a modifiable contributor to safer outcomes for mother and baby

9:00am – 10:30am | Room 325

Chairs: Ghada Bourjeily (United States), Danielle Wilson (Australia)

9:00am – 9:02am

Introduction

9:02am – 9:22am

Sleep as an opportunity to improve maternal and fetal health outcomes

Ghada Bourjeily (United States)

9:22am – 9:42am

Can sleeping position during pregnancy impact fetal growth and wellbeing?

Danielle Wilson (Australia)

9:42am – 10:02am

Non-pharmacological interventions for sleep in pregnancy

Meagan Crowther (Australia)

10:02am – 10:22am

Treatment of sleep disordered breathing in pregnancy

Visasiri Tantrakul (Thailand)

10:22am – 10:30am

Question and answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

S-52: Sleep Challenge 2025 Exhibition:

Predicting all-cause mortality using physiological signals from the PSG

9:00am – 10:30am | Room 326

Chairs: Diane Lim (United States), Toshihiro Imamura (United States)

9:00am – 9:02am

Introduction

9:02am – 9:18am

Sleep challenges: A catalyst for big data innovation and transformation

Diane Lim (United States)

9:18am – 9:34am

Chaos theory-driven approach to analyzing biosignals

Yu-Hsin Chen (Taiwan)

9:34am – 9:50am

Deep learning models to detect sleep patterns

Poul Jørgen Jennum (Denmark)

9:50am – 10:06am

Physiological networks applied to sleep apnea patients

Ronny Bartsch (Israel)

10:06am – 10:22am

A clinically guided weighted hypoxemia approach for mortality prediction

Cheng-Bang Chen (United States)

10:22am – 10:30am

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-17: Biomarkers, phenotyping, and cognitive aspects in narcolepsy and hypersomnolence

9:00am – 10:30am | Room 327

Chairs: MaoHuan Peng (China), Clete Kushida (United States)

9:00am – 9:13am

Multimodal Detection of Narcolepsy Type 1 Using Genetic and Nocturnal Polysomnography Data

Dmitri Volfson (United States)

9:13am – 9:26am

Clinical and Polysomnographic Differences Among Child-, Adolescent-, and Adult-Onset Type 1

Narcolepsy: A Chinese Cohort Study

MaoHuan Peng (China)

9:26am – 9:39am

Single-cell RNA and TCR sequencing of cerebrospinal fluid cells from patients with recentonset type 1 narcolepsy

Shuang Yue (China)

9:39am – 9:52am

Narcolepsy’s Sustained Attention Deficits: Unveiled by Dysfunctional Brain Dynamics

Xiao Han (China)

9:52am – 10:05am

Precision medicine approach in Brazilian patients with primary hypersomnias using hypocretin and high-resolution HLA sequencing : insights from a multiethnic population

Christianne Martins Correa da Silva (Brazil)

10:05am – 10:18am

Clinically Meaningful Improvement in Daytime

Sleepiness With ON-SXB in People With Narcolepsy and Severe Sleepiness

Clete Kushida (United States)

FRIDAY

September 5, 2025

Scientific Program | TUESDAY

O-18: Tracking sleep: Tools, trends, and tailored interventions

9:00am – 10:30am | Room 328

Chair: Kelly Baron (United States)

9:00am – 9:13am

Tired and Wired: Sleep Deprivation Prevents

Affective Renormalisation During Exposure to Ambiguous Threat

Emma Sullivan (United Kingdom)

9:13am – 9:26am

Uncovering Sleep-Linked Glucose Dynamics in Healthy Individuals Using Wearable Data

Zilu Liang (Japan)

9:26am – 9:39am

How the Visual Urban Landscape Influences Sleep Health via Subjective Neighborhood Evaluation

Xiaorui Wang (Japan)

9:39am – 9:52am

Timing Matters: Differential Associations of PreBedtime vs. In-Bed Objective Phone Use with Sleep among University Students

Zhenghao Pu (Singapore)

9:52am – 10:05am

Effects of a behavioral sleep extension intervention on actigraphically measured sleep and patient reported outcomes

Kelly Baron (United States)

10:05am – 10:18am

Identifying sleep associations in women across five countries: a global smartwatch-based study

Claudio N. Soares (Canada)

MONDAY September 8, 2025

TUESDAY September 9, 2025

O-19: New Investigator Award

9:00am – 10:30am | Room 329

10, 2025

Chairs: Charles Morin (Canada), Thomas Penzel (Germany)

9:00am – 9:13am

Investigating differential rhythmicity in circadian biomarkers using skin perspiration wearables

Annapoorna Ramasubramanya (United States)

9:13am – 9:26am

Association of Outdoor Artificial Light at Night with Sleep Duration and Social Jetlag Among Preschoolaged Children

Qiu-Ye Lan (China)

9:26am – 9:39am

Mandibular advancement device versus CPAP on cardiovascular health and quality of life in OSA ─ a pre-specified 12 months follow up of outcome

Yi Hui Ou (Singapore)

9:39am – 9:52am

Distinct gut microbial, brain gene expression and clinical progression profiles in REM sleep behavior disorder biotypes

Shi Tang (Hong Kong)

9:52am – 10:05am

REM-sleep saw-tooth waves: cortical topography and associations with cognition

Irina Filchenko (Switzerland)

10:05am – 10:18am

A Pilot Study of Personalized Obstructive Sleep

Apnea Therapy in Patients with Acute Coronary Syndrome

Benjamin K Tong (Australia)

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app! SCAN TO

Supported by

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

O-20: Sleep and sleep deprivation neurophysiology

9:00am – 10:30am | Room 330

Chairs: Federico Salfi (Italy), Eunyeon Joo (Korea, Republic of)

9:00am – 9:13am

Sleep Macro- and Microarchitecture in Major Depressive Disorder with Sleep State Misperception

Jiong Chen (China)

9:13am – 9:26am

Sleep’s Protective Effect on Fear Overgeneralization: The Role of REM Sleep and Theta Oscillations

Tianqi Di (China)

9:26am – 9:39am

Sleep Restriction Affects Sequential Updating Through Increasing Reward Sensitivity

Jeryl, Yin Liang Lim (Australia)

9:39am – 9:52am

An experimental study on the effects of railway vibration on sleep and the blood metabolome

Michael Smith (Sweden)

9:52am – 10:05am

The contribution of theta activity preceding cortical down-states to the slow oscillatory-spindle dynamics of human non-REM sleep

Federico Salfi (Italy)

10:05am – 10:18am

The Role of Adenosine Receptors and Their Antagonist Caffeine in the Mouse Hippocampal CA2 Region Associated with Sleep Deprivation

Lik Wei Wong (Singapore)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

Narcolepsy Group Workshop with Takeda

10:00am – 10:45am | Room 302

An Experiential Journey with Stigma: Understanding Stigma and its Impact on Diagnosis and Quality of Life for People Living with Narcolepsy

Yoshika Sherring (United States), Lindsay Jesteadt (United States), Anne Marie Morse (United States), Aaron Schokman (Australia), Kerry Johnson (United States)

S-53: Illuminating the minds: Impact of light exposure on circadian rhythms and health

10:45am – 12:15pm | Hall 406 C

Chairs: Joey Chan (Hong Kong)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Light exposure and neuropathology in schizophrenia

Yuichi Esaki (Japan)

11:07am – 11:27am

Real world light exposure patterns and mental health

Sean Cain (Australia)

11:27am – 11:47am

Alterations of Melanopsin-mediated Pupillary Response in Patients with REM Sleep Behavior Disorder and Parkinson’s Disease

Joey Chan (Hong Kong)

11:47am – 12:07pm

Light, circadian rhythm, and neuropsychiatric diseases

Jihui Zhang (China)

12:07pm – 12:15pm

Question and answer

FRIDAY

September 5, 2025

September 6, 2025

Scientific Program | TUESDAY

S-54: Advancing the definition and management of childhood obstructive sleep apnea (OSA)

10:45am – 12:15pm | Hall 406 D

Chairs: Indra Narang (Canada), Albert Li (China)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Improving sleep in children with Down syndrome

Rosemary Horne (Australia)

11:07am – 11:27am

EEG characteristics and cognitive dysfunction in children with OSA

Zhifei Xu (China)

11:27am – 11:47am

Can adenotonsillectomy in childhood enhance longterm cardiovascular health for individuals with OSA?

Jun Chun Ting Au (Canada)

11:47am – 12:07pm

Optimizing treatment for pediatric OSA: Insights from HFNC and CPAP therapies

Kate Chan (Hong Kong)

12:07pm – 12:15pm

Question and answer

Supported by

MONDAY September 8, 2025

TUESDAY September 9, 2025

September 7, 2025 WEDNESDAY September 10, 2025

S-55: Advancing ambulatory sleep monitoring and diagnostics through innovative sensor technologies

10:45am – 12:15pm | Nicoll 1

Chairs: Ralf Seepold (Germany),

Natividad Martínez Madrid (Germany)

10:45am – 10:47am

Introduction

10:47am – 11:03am

Development and verification of a neck-wearable

Piezoelectric sensor for detecting snoring and sleep apnea from snoring and carotid pulse signals

Li-Ang Lee (Taiwan)

11:03am – 11:19am

Innovative sleepiness monitoring system using speech and wearable electrodermal activity signals

Ralf Seepold (Germany)

11:19am – 11:35am

Analysis of sleep and speech patterns for the diagnosis of impulse control disorders in adolescents

Natividad Martínez Madrid (Germany)

11:35am – 11:51am

All-night EEG-fNIRS as a novel tool for investigating sleep physiology

Christophe Grova (Canada)

11:51am – 12:07pm

Quantification of REM sleep without atonia in natural sleep environment

Shani Oz (Israel)

12:07pm – 12:15pm

Question and answer

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

SCAN TO DOWNLOAD THE WORLD SLEEP 2025 APP!

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

S-56: Obesity and the effects of GLP-1 agonists on OSA

10:45am – 12:15pm | Nicoll 2

Chairs: Richard Schwab (United States), Ron Grunstein (Australia)

10:45am – 10:47am

Introduction

10:47am – 11:03am

Relationship of upper airway anatomy and obesity in patients with OSA: The Icelandic Sleep Cohort Liyue (Adell) Xu (China)

11:03am – 11:19am

Effect of weight loss on pharyngeal soft tissues including reductions in tongue fat from MRI studies

Richard Schwab (United States)

11:19am – 11:35am

Effect of Liraglutide on OSA in patients with type 2

DM - the ROMANCE trial

Dan Cuthbertson (United Kingdom)

11:35am – 11:51am

Highlights from the Surmount OSA trial and what are the next treatments on the horizon

Ron Grunstein (Australia)

11:51am – 12:07pm

How do GLP-1 agonists fit into OSA management pathways and will they a game change?

Vaishnavi Kundel (United States)

12:07pm – 12:15pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-57: Narcolepsy meets immunology: Recent global discoveries in its pathophysiology

10:45am – 12:15pm | Nicoll 3

Chairs: Emmanuel Mignot (United States), Rolf Fronczek (Netherlands)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Mechanistic insights into the autoimmune hypothesis of narcolepsy: Novel cellular and animal findings

Christelle Peyron (France)

11:07am – 11:27am

A European perspective on the role of immunological triggers on the development of central disorders of hypersomnolence

Jari Gool (Netherlands)

11:27am – 11:47am

The role of different influenza strains on the onset of narcolepsy in the United States

Emmanuel Mignot (United States)

11:47am – 12:07pm

The role of upper airway infection as trigger for children narcolepsy type 1 in China

Fang Han (China)

12:07pm – 12:15pm

Question and answer

FRIDAY September 5, 2025

Scientific Program | TUESDAY

S-58: Discussion group: Religious and spiritual determinants of sleep health

10:45am – 12:15pm | Room 303

Chair: Chandra Jackson (United States)

10:45am – 12:15pm

Discussants

Chandra Jackson (United States)

Rupsha Singh (Nepal)

Hamza Dhafar (Saudi Arabia)

S-59: Understanding the therapeutic opportunities of iron treatment in RLS

10:45am – 12:15pm | Room 308

Chairs: Diego Garcia-Borreguero (Spain), Claudia Trenkwalder (Germany)

10:45am – 10:47am

Introduction

10:47am – 11:07am

The therapeutic efficacy of iron supplementation in adults

Claudia Trenkwalder (Germany)

11:07am – 11:27am

Measuring serum vs brain iron status. The use of SN Ultrasound in RLS

Diego Garcia-Borreguero (Spain)

11:27am – 11:47am

Iron deficiency and augmentation

Chung-Yao Hsu (Taiwan)

11:47am – 12:07pm

The therapeutic efficacy of iron supplementation in the pediatric population

Gulcin Benbir Senel (Türkiye)

12:07pm – 12:15pm

Question and answer

TUESDAY September 9, 2025

S-60: Collaborative strategies for optimizing pediatric sleep health

10:45am – 12:15pm | Room 309

Chairs: Leopoldo Pedro Correa (Mexico), Christine Hong (United States)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Precision Growth modification targeting craniofacial skeletal phenotype of pediatric OSA

Su-Jung Kim (Korea, Republic of)

11:07am – 11:27am

Biology of maxillary expansion and its effect on upper airway

Christine Hong (United States)

11:27am – 11:47am

Orofacial myofunctional therapy as adjunct in treating obstructive sleep apnea

Rochelle McPherson (Australia)

11:47am – 12:07pm

Pathophysiological and anatomical factors in pediatric OSA: Path towards precision medicine

Umakanth Katwa (United States)

12:07pm – 12:15pm

Question and answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

S-61: Sleep and the microbiome

10:45am – 12:15pm | Room 324

Chairs: Dalva Poyares (Brazil), Yun Kwok Wing (Hong Kong)

10:45am – 10:47am

Introduction

10:47am – 11:07am

Brain-gut-microbiota interactions in sleep disorders

Lin Lu (China)

11:07am – 11:27am

Obstructive sleep apnea, hypoxia, and the microbiota

Jean-Louis Pépin (France)

11:27am – 11:47am

Sleep bruxism and putative role(s) of the oral microbiota: Caution in extrapolation

Gilles J Lavigne (Canada)

11:47am – 12:07pm

Is there a role for probiotics in the treatment of insomnia disorder and psychological symptoms?

Charles Morin (Canada)

12:07pm – 12:15pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-62: Rethinking mask selection for CPAP and non-invasive ventilation: Facts and perspectives

10:45am – 12:15pm | Room 325

Chairs: Pedro Genta (Brazil), Patrick Strollo (United States)

10:45am – 10:47am

Introduction

10:47am – 11:03am

Mask side-effects: Distinguishing between mouth and mask leak

Pedro Genta (Brazil)

11:03am – 11:19am

Performance of nasal and oronasal masks for CPAP

treatment: Current evidence

Patrick Strollo (United States)

11:19am – 11:35am

The importance of mask selection for home noninvasive ventilation

Amanda Piper (Australia)

11:35am – 11:51am

Digital facial imaging for artificial intelligenceguided mask fitting applications

Timothy Morgenthaler (United States)

11:51am – 12:07pm

Common biases leading to incorrect mask selection

Ana C. Krieger (United States)

12:07pm – 12:15pm

Question and answer

FRIDAY

September 5, 2025

September 6, 2025

Scientific Program | TUESDAY

S-63: Global efforts to combat drowsy driving: Opportunities and challenges to save more lives

10:45am – 12:15pm | Room 326

Chairs: Andrew Vakulin (Australia), Arezu Najafi (Iran)

10:45am – 10:47am

Introduction

10:47am – 11:03am

Drowsy driving: Summary of the scientific evidence on the causes, prevalence, consequences and costs

Clare Anderson (United Kingdom)

11:03am – 11:19am

Overview of international regulations on sleep disorders and drowsy driving across the world

Walter McNicholas (Ireland)

11:19am – 11:35am

Overview of international public health and road design approaches to reducing drowsy driving

Arezu Najafi (Iran)

11:35am – 11:51am

Summary of research evidence on detecting driver state and trait drowsiness from laboratory and onroad driving studies and commercial vehicle systems

Mark Howard (Australia)

11:51am – 12:07pm

Gaps in regulations and public health initiatives to reduce drowsy driving crashes in private drivers and related solutions

Andrew Vakulin (Australia)

12:07pm – 12:15pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

7, 2025 WEDNESDAY September 10, 2025

O-21: Phenotyping and variability in obstructive sleep apnea: Implications for cardiovascular risk and personalized management

10:45am – 12:15pm | Room 327

Chairs: Danny Eckert (Australia), Mary Carskadon (United States)

10:45am – 10:58am

Multi-night monitoring of variability in OSA severity and associated impacts on daytime impairment and quality of life

Simon Proctor (Australia)

10:58am – 11:11am

Data-Driven Identification of OSA Subtypes through Endotypic Clustering in Multi-Cohort Population Studies

Sue Jung Lee (Korea, Republic of)

11:11am – 11:24am

The combined effect of acetazolamide and oxygen (ACZO2) on OSA severity and endotypes

Shane Landry (Australia)

11:24am – 11:37am

Respiratory self-similarity is a sleep apnea endotype that predicts cardiovascular disease related mortality in community-dwelling subjects

Yuenan Ni (China)

11:37am – 11:50am

Sleep-stage dynamics predicts current sleepdisordered-breathing and future cardiovascular risk

Michal Bechny (Switzerland)

11:50am – 12:03pm

High night-to-night variability in OSA severity is associated with prevalent major adverse cardiovascular and cerebrovascular events

Bastien Lechat (Australia)

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

O-22: The science of sleep health: Biomarkers, behavior, and big data

10:45am – 12:15pm | Room 328

Chairs: Matteo Cesari (Austria), Julio Fernandez-Mendoza (United States)

10:45am – 10:58am

Digital cognitive-behavioral therapy-based treatment for insomnia, nightmares and posttraumatic stress disorder symptoms in wildfire survivors: A randomized feasibility pilot trial

Fadia Isaac (Australia)

10:58am – 11:11am

Relationships between sleep and daily step count examined using large-scale, home-based, health monitoring data

Josh Fitton (Australia)

11:11am – 11:24am

Association Between Daily Step Count and Sleep Health: Findings from a National Survey in China

Xinyu Fu (China)

11:24am – 11:37am

Associations Between Sleep Health and Gut Microbiota: A Metagenomic Analysis in a Community-Based Sample in Hong Kong

Suyi Xie (Hong Kong)

11:37am – 11:50am

Cerebral Metabolic Abnormalities and Disrupted Gut Microbiota in Adolescents with Major Depressive Disorder and Comorbid Insomnia Symptoms: A Proton Magnetic Resonance Spectroscopy Study

Shuming Zhong (China)

11:50am – 12:03pm

Where You Live Shapes How You Sleep: Geographic and Cultural Influences on Sleep Duration in Global Data Measured by the Galaxy Watch

Pamela Song (Korea, Republic of)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-23: Neurophysiological signatures and technological innovations in sleep apnea detection and impact assessment

10:45am – 12:15pm | Room 329

Chairs: Virend Somers (United States), Ingo Fietze (Germany)

10:45am – 10:58am

Sleep spindle characteristics in children with OSA and their associations with declarative memory function

Mingqi Dong (China)

10:58am – 11:11am

Electroencephalographic response to respiratory events is associated with all-cause mortality in obstructive sleep apnea

Mohammadreza Hajipour (United States)

11:11am – 11:24am

A Multi-Task Deep Learning Model for Sleep Staging and Apnea Detection Using Single-Channel EEG

Hyun Kyung Lee (Korea, Republic of)

11:24am – 11:37am

Dynamic Changes in Pulse Propagation Time

Following Respiratory Events are Associated with Cortical Arousals in Obstructive Sleep Apnea

Christian Strassberger (Sweden)

11:37am – 11:50am

AI-rway A Scalable Smartphone based Airway Screening tool for OSA and SDB for use @ Scale in pediatric and adult populations

Paramesh Gopi (United States)

11:50am – 12:03pm

Supplemental Low-Dose CO₂ Delivered by a Novel Device Abolishes Central Sleep Apnea at High Altitude

Yuanming Luo (United States)

FRIDAY

September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | TUESDAY

O-24: Treatment and risk factor modifications in circadian rhythm disorders

10:45am – 12:15pm | Room 330

Chairs: Kathryn Reid (United States), Diane Boivin (Canada)

10:45am – 10:55am

Aripiprazole (Abilify) as a new treatment for circadian rhythm sleep-wake disorders (CRSWDs) and its mechanism of action

Takashi Kanbayashi (Japan)

10:55am – 11:05am

Clinical Trial of Solriamfetol in Early Morning Shift Workers

Kirsi-Marja Zitting (United States)

11:05am – 11:15am

Late Isocaloric Eating Delays Circadian Rhythm of Glucose Tolerance in Adults with Overweight and Obesity

Han-Chow Koh (United States)

11:15am – 11:25am

Work ability and health-related productivity loss by chronotype: Results from population-based panel study

Mo-Yeol Kang (Korea, Republic of)

11:25am – 11:35am

Evaluation of the Molecular Crosstalk Between Endoplasmic Reticulum Stress and Sleep-Wake Homeostasis

Guohao Ni (United Kingdom)

11:35am – 11:45am

Chronotype and infradian rhythms: the influence of solar and lunar cycles on sleep duration and phase

Simone Bruno (United States)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

BMC Medical: Detecting all Central Events using CPAP - What’s the point?

11:15am – 12:00pm | Room 302

Detecting all Central Events using CPAPWhat’s the point?

Xiaolei Zhang (China), Renata Riha (United Kingdom)

New directions in multi-disciplinary education

12:20pm – 1:15pm | Room 302

Chairs: Jatuporn Wanchaitanawong (Thailand), Huiji Yi (China)

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

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FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

Medscape: Education Global: Global Perspectives in Narcolepsy: Learning From Each Other

12:45pm – 1:45pm | Hall 406 C

Chair: Yuichi Inoue (Japan)

Supported by an independent educational grant from Takeda.

12:45pm – 12:55pm Welcome and Introduction

Yuichi Inoue (Japan)

12:55pm – 1:05pm Narcolepsy Type 1: Journeys to a Tricky Diagnosis

Anne Marie Morse (United States)

1:05pm – 1:20pm Awake but Not Alert: Cognitive Performance in Narcolepsy

Lucie Barateau (France)

1:20pm – 1:30pm Mechanisms of Impaired Cognition in Narcolepsy

Thomas Scammell (United States)

1:30pm – 1:43pm Panel Discussion and Audience Q&A

1:43pm – 1:45pm Summary and Close

Yuichi Inoue (Japan)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

Philips Sleeposium: Frontiers of Sleep Sciences in 2025

12:45pm – 1:45pm | Hall 406 D Chair: Song Tar Toh (Singapore)

Collaboratively shaping the future of sleep medicine: Emerging trends that will affect us all Teofilo Lee-Chiong (United States)

AI in Sleep Medicine: Navigating Innovation and Implementation Challenges

Ahmed BaHammam (Saudi Arabia)

Personalization and customization of sleep therapy

Naricha Chirakalwasan (Thailand)

Panel Discussion

FRIDAY

September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025

Scientific Program | TUESDAY

Idorsia: Managing insomnia disorder in patients with neurological and psychiatric comorbidities

12:45pm – 2:15pm | Nicoll 1

Chairs: David Neubauer (United States), Lu Lin (China)

12:45pm – 1:05pm

The impact of insomnia disorder for patients

David Neubauer (United States)

1:05pm – 1:25pm

New clinical data on daridorexant for managing insomnia disorder

Atul Khullar (Canada)

1:25pm – 1:45pm

Clinical experience managing insomnia disorder in patients with psychiatric comorbidities

Laura Palagini (Italy)

1:45pm – 2:05pm

Clinical experience managing insomnia disorder in patients with neurological comorbidities

Claudio Liguori (Italy)

2:05pm – 2:15pm

Panel discussion and Q&A

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

Transforming Sleep Science with Wearable and Next Generation Technology: Samsung Opportunities and Case Studies

12:45pm – 1:45pm | Nicoll 3

Chair: Jennifer Kanady (United States)

12:45pm – 12:50pm

Welcome and Samsung Health Introduction

Jongmin Choi (Korea, Republic of)

12:50pm – 1:00pm

Beyond the Lab: How Wearables and Next-Gen Tech are Advancing Sleep Health and Research

Jennifer Kanady (United States)

1:00pm – 1:10pm

Samsung Health SDK Suite: Inspiring the Future through Research and Innovation Moonbae Song (Korea, Republic of)

1:10pm – 1:25pm

Case Study One: Bayer

Consumer wearables and women’s health: Real-world insights into sleep disturbances associated with menopausal transition

Cecilia Caetano (Switzerland)

1:25pm – 1:40pm

Case Study Two: KAIST

AI + Math Meets Physiology: Scalable Personalized Sleep Scheduling via Samsung Health

Jaekyoung Kim (Korea, Republic of)

1:40pm – 1:45pm

Question and answer

Jennifer Kanady (United States)

Introduction to next Samsung Symposium and Booth Exhibition

Jennifer Kanady (United States)

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

Nox Medical: Precision Breathing: Advancing

Sleep Apnea Phenotyping Through Accurate Flow Measurement

12:45pm – 1:45pm | Room 309

Chairs: Fang Han (China), Liang-wen Hang (Taiwan)

Flow matters: Unlocking the diagnostic power of Nox Flow

Jon Agustsson (Iceland)

Mapping mechanisms: Phenotyping the pathophysiology of obstructive sleep apnea

Scott Sands (United States), Jon Agustsson (Iceland)

Beyond AHI: How phenotyping is redefining sleep apnea treatment at the bedside

Wan-Ju Cheng (Taiwan)

World Sleep Academy Research Showcase

2:00pm – 4:00pm | Room 302

Türkiye

Ezgi Baris (Türkiye), Elif Öztürk (Türkiye), Mahmut Caner Us (Türkiye)

Peru

Monica Caycho (Peru)

Serbia

Dragan Hrnčić (Serbia)

Vietnam

Khue Bui-Diem (Vietnam), Tai Tran (Vietnam)

India

Ramya Rathod (India)

Japan

Yoshinori Saito (Japan)

Colombia

Ana María Silva (Argentina)

China

Siyu Dai (China)

Zimbabwe

Priscilla Zimani (Zimbabwe)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

K-07: Mary Ip

Cardiometabolic consequences of obstructive sleep apnea: Are we making progress?

2:15pm – 3:00pm | Hall 406 C

2:15pm – 2:17pm

Introduction

Sutapa Mukherjee (Australia)

2:17pm – 3:00pm

Cardiometabolic consequences of obstructive sleep apnea: Are we making progress?

Mary Ip (Hong Kong)

K-08: Célyne Bastien

Sleep misperception: A waking perspective

2:15pm – 3:00pm | Hall 406 D

2:15pm – 2:17pm

Introduction

Dalva Poyares (Brazil)

2:17pm – 3:00pm

Sleep misperception: A waking perspective

Célyne Bastien (Canada)

S-64: Managing patients with obstructive sleep apnea and obesity with GLP-1 receptor agonists

3:15pm – 4:45pm | Hall 406 C

Chairs: Clete Kushida (United States), Patrick Strollo (United States)

Discussants

Clete Kushida (United States), Patrick Strollo (United States), Christine Won (United States), Danny Eckert (Australia), Ingo Fietze (Germany), Najib Ayas (Canada)

FRIDAY

Scientific Program | TUESDAY

S-65: Night shift work and health risks: Internal desynchrony and underlying mechanisms

3:15pm – 4:45pm | Hall 406 D

Chair: Hans Van Dongen (United States)

3:15pm – 3:17pm

Introduction

3:17pm – 3:37pm

Multi-omics of simulated night shift work: Evidence of widespread metabolic desynchrony

Hans Van Dongen (United States)

3:37pm – 3:57pm

Real-world rotating shift schedules and internal circadian disruption of metabolism

Diane Boivin (Canada)

3:57pm – 4:17pm

Eating at night and its circadian impacts on metabolism

Siobhan Banks (Australia)

4:17pm – 4:37pm

Meal timing and the regulation of glucose metabolism and immunity

Leonie Heilbronn (Australia)

4:37pm – 4:45pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

September 5, 2025 SATURDAY September 6, 2025 SUNDAY September 7, 2025 WEDNESDAY September 10, 2025

S-66: Phenotypic spectrum of restless legs syndrome: Clinical insights and research perspectives

3:15pm – 4:45pm | Nicoll 1

Chairs: Diego Garcia-Borreguero (Spain), Gulcin Benbir Senel (Türkiye)

3:15pm – 3:17pm Introduction

3:17pm – 3:37pm

Introduction: The phenotypic clinical diversity of RLS

Diego Garcia-Borreguero (Spain)

3:37pm – 3:57pm

Pediatric RLS phenotypes: Early onset and unique challenges

Lourdes DelRosso (United States)

3:57pm – 4:17pm

Adult RLS phenotypes: Clinical variability in adulthood

Claudia Trenkwalder (Germany)

4:17pm – 4:37pm

Genetic insights into RLS: Shared variants and comorbidities

Arthur Walters (United States)

4:37pm – 4:45pm Question and answer

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

Supported by

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FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

S-67: Toward understanding dream interpretation: Mechanisms and functions of REM sleep

3:15pm – 4:45pm | Nicoll 2

Chairs: Yu Hayashi (Japan), Shoi Shi (Japan)

3:15pm – 3:17pm

Introduction

3:17pm – 3:37pm

Mapping the neurophysiological correlates of dreams in sleep

Francesca Siclari (Netherlands)

3:37pm – 3:57pm

Neural network models of hippocampal computations during sleep

Louis Kang (Japan)

3:57pm – 4:17pm

Sodium leak channel uncovers the molecular mechanism regulating REM sleep and the function of REM sleep

Hiromasa Funato (Japan)

4:17pm – 4:37pm

Brain-body interactions underlying REM sleep regulation and threat responses

Liping Wang (China)

4:37pm – 4:45pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-68: Adolescent sleep and mental health: From challenges to solutions

3:15pm – 4:45pm | Nicoll 3

Chairs: Shirley Xin Li (Hong Kong), Michael Gradisar (Sweden)

3:15pm – 3:17pm Introduction

3:17pm – 3:33pm

Caught between books and beds: The impact of sleep deprivation and sleep disturbance on Taiwanese adolescents’ mental health

Ya-wen Jan (Taiwan)

3:33pm – 3:49pm

Adolescent sleep and implications for school performance and mental health – Results from a Norwegian cohort of older adolescents

Ingvild West Saxvig (Norway)

3:49pm – 4:05pm

New subtypes of insomnia and their association with mental health in children and adolescents

Guanghai Wang (China)

4:05pm – 4:21pm

Late owl phenomenon and sleep deprivation in adolescents: Is advancing bedtime effective?

Sijing Chen (Hong Kong)

4:21pm – 4:37pm

Comorbid insomnia and anxiety in youth – Shall we tackle sleep or anxiety problem in treatment?

Xiao Li (Hong Kong)

4:37pm – 4:45pm

Question and answer

FRIDAY

September 5, 2025

September 6, 2025

Scientific Program | TUESDAY

S-69: Discussion group: Global perspectives on sleep health advocacy: Insights and experiences across five continents

3:15pm – 4:45pm | Room 303

Chairs: Rebecca Robillard (Canada), Arezu Najafi (Iran)

3:15pm – 4:45pm Discussants

Arezu Najafi (Iran), Jason Ellis (United Kingdom), Morenikeji Komolafe (Nigeria), Julie Flygare (United States), Andrew Vakulin (Australia), Rebecca Robillard (Canada)

S-70: Ecology of sleep strategies: Placing sleep function in a broader context

3:15pm – 4:45pm | Room 308

Chairs: Markus Schmidt (Switzerland), Gianina Ungurean (Germany)

3:15pm – 3:17pm

Introduction

3:17pm – 3:33pm

Introduction – A mammalian and Bird’s Eye perspective of sleep diversity

Gianina Ungurean (Germany)

3:33pm – 3:49pm

Ecological flexibility in seep duration

Niels Rattenborg (Germany)

3:49pm – 4:05pm

Long-term monitoring of sleep-wake behaviors and the role of ambient ecological conditions

Isabella Capellini (United Kingdom)

4:05pm – 4:21pm

Comparative studies of seasonal impacts on sleep expression in birds and mammals

Peter Meerlo (Netherlands)

4:21pm – 4:37pm

Strategies of resource optimization through sleepwake alternation

Markus Schmidt (Switzerland)

4:37pm – 4:45pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

10, 2025

S-71: Cracking the code: Deep signal analysis in sleep-disordered breathing

3:15pm – 4:45pm | Room 309

Chairs: Ding Zou (Sweden), Liang-wen Hang (Taiwan)

3:15pm – 3:17pm

Introduction

3:17pm – 3:33pm

Morphological flow analysis for high loop gain in adults and kids

Robert Thomas (United States)

3:33pm – 3:49pm

Centralness of respiratory events: A novel tool to guide non-PAP interventions in sleep disordered breathing

Scott Sands (United States)

3:49pm – 4:05pm

Beyond Desaturations: Leveraging Pulse Oximetry for Comprehensive Diagnosis

Henri Korkalainen (Finland)

4:05pm – 4:21pm

Endotypic traits characterizing obesity and sleeprelated hypoventilation in patients with obstructive sleep apnea

Wan-Ju Cheng (Taiwan)

4:21pm – 4:37pm

Cluster analysis in OSA: Opening the black box of AI with explainable modelling

Daniil Lisik (Sweden)

4:37pm – 4:45pm

Question and answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

S-72: Advances in proteomics, glycomics, and transcriptomics of sleep disorders

3:15pm – 4:45pm | Room 324

Chairs: Raffaele Ferri (Italy), Maria Paola Mogavero (Italy)

3:15pm – 3:17pm

Introduction

3:17pm – 3:37pm

Proteomic and metabolomic perspectives in the study of PLMS/RLS

Katie L.J. Cederberg (United States)

3:37pm – 3:57pm

Integrative proteomics and glycomics in narcolepsy: Biomarkers and mechanistic insights

Yehia Mechref (United States)

3:57pm – 4:17pm

New insights into Kleine-Levin syndrome: Orexin and omics biomarkers

Fang Han (China)

4:17pm – 4:37pm

Decoding the proteomic and transcriptomic landscape of restless legs syndrome

Maria Paola Mogavero (Italy)

4:37pm – 4:45pm Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

S-73: Discussion group: “Simple” snoring: Not simple, not hopeless

3:15pm – 4:45pm | Room 325

Chairs: Ofer Jacobowitz (United States), Edilson Zancanella (Brazil)

3:15pm – 3:17pm Introduction

3:17pm – 3:33pm

Devices and Aids for Snoring : Does Anything Work?

Ofer Jacobowitz (United States)

3:33pm – 3:49pm

The approach to the snoring patient

Edilson Zancanella (Brazil)

3:49pm – 4:05pm

First in Line, the Nose

Jessica Schwarts (United Arab Emirates)

4:05pm – 4:21pm

Palatal Vibrations, How to Treat Dipankar Datta (India)

4:21pm – 4:37pm

Case Presentations & Panel Discussion

Stuart MacKay (Australia)

4:37pm – 4:45pm Question and answer

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

S-74: Harmonizing pediatric sleep: Navigating the complexities and diversities in managing sleep-related breathing disorders across borders

3:15pm – 4:45pm | Room 326

Chairs: Karen Spruyt (France), Umakanth Katwa (United States)

3:15pm – 3:17pm Introduction

3:17pm – 3:33pm

The South American perspective

Gustavo Moreira (Brazil)

3:33pm – 3:49pm

The Asian perspective

Kate Chan (Hong Kong)

3:49pm – 4:05pm

The USA perspective

Umakanth Katwa (United States)

4:05pm – 4:21pm

The African perspective

Eniola Eziyi (Nigeria)

4:21pm – 4:37pm

The European perspective

Palma Benedek (Hungary)

4:37pm – 4:45pm

Question and answer

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-25: Biomarkers and neuroimaging in prodromal RBD and synucleinopathies

3:15pm – 4:45pm | Room 327

Chairs: Federica Provini (Italy), Shady Rahayel (Canada)

3:15pm – 3:28pm

Glymphatic defect in isolated REM sleep behavior disorder is associated with phenoconversion to Parkinson’s disease

Léa Bastien (Canada)

3:28pm – 3:41pm

[18F]FDG-PET as staging biomarker in the prodromal to overt neuronal alpha-synucleinopathy continuum

Beatrice Orso (Italy)

3:41pm – 3:54pm

Free water imaging predicts phenoconversion in isolated REM sleep behavior disorder: a longitudinal, multicentre, prospective cohort study

Celine Haddad (Canada)

3:54pm – 4:07pm

Free water is increased within the basal forebrain and suprachiasmatic pathways of isolated REM sleep behavior disorder

Shady Rahayel (Canada)

4:07pm – 4:20pm

Brain Connectivity Alterations in Idiopathic REM Sleep Behavior Disorder: A Multi-Cohort Study

Christina Tremblay (Canada)

4:20pm – 4:33pm

Progression of prodromal markers of alphasynucleinopathy neurodegeneration in the firstdegree relatives of patients with REM sleep behavior disorder: a 7-year prospective study

Ningning Li (Hong Kong)

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

SCAN TO DOWNLOAD THE WORLD SLEEP 2025 APP! Supported by

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

O-26: Infant and preschool sleep: Patterns and problems

3:15pm – 4:45pm | Room 328

Chairs: Rosemary Horne (Australia), Judith Owens (United States)

3:15pm – 3:28pm

Feasibility and clinical utility of daytime polysomnography performed in NICU to diagnose sleep disordered breathing in infants

Dimple Goel (Australia)

3:28pm – 3:41pm

Comparison of Treatment Efficacy Between Rapid Maxillary Expansion and Adenotonsillectomy in Children With Obstructive Sleep Apnea: An RCT

Supakit Peanchitlertkajorn (Thailand)

3:41pm – 3:54pm

Toddler Sleep Patterns: Exploring Associations Between Bedtime Consistency and Routines, Parental Involvement and Sleep Outcomes

Monica Ordway (United States)

3:54pm – 4:07pm

A Quest for a Histaminergic or Orexinergic Biomarker for Sudden Infant Death Syndrome

Patricia Franco (France)

4:07pm – 4:20pm

Slower maturation of the circadian rest-activity rhythm is associated with weight gain across infancy

Megan Petrov (United States)

4:20pm – 4:33pm

Diagnostic Accuracy of a Contactless Sleep Mat; “The Sonomat®” compared to Level 1 Polysomnography in Children with Neurodisability – Findings from an Australian Multi-Centre Trial

Jasneek Chawla (Australia)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

O-27: Rethinking daytime sleepiness: Multimodal approaches to identification and management

3:15pm – 4:45pm | Room 329

Chairs: Thomas Scammell (United States), Lucie Barateau (France)

3:15pm – 3:28pm

Bordeaux Sleepiness Scale (BOSS): A new scale to predict sleep-related traffic accident in regular French highway drivers

Pierre Philip (France)

3:28pm – 3:41pm

Association of Hypnotics with Dementia and Cognitive Function in Insomnia Patients: An Observational and Two-sample Mendelian Randomization study

Sizhi Ai (China), Huiying Zhang (China)

3:41pm – 3:54pm

Altered sleep spindle morphology in idiopathic hypersomnia

Samantha Mombelli (Canada)

3:54pm – 4:07pm

Optimizing timing and dose of melatonin administration: a randomized, double-blind controlled trial in healthy adults

Simone Bruno (United States)

4:07pm – 4:20pm

Detection of Phoneme Sequences in Spontaneous Speech for the Characterization of Excessive Daytime Sleepiness: a new method to be compared to MSLT

Colleen Beaumard (France)

4:20pm – 4:33pm

Metabolomic Profiling of Kleine-Levin Syndrome In and Out of Episode using Liquid ChromatographyMass Spectrometry

Liyue (Adell) Xu (China)

4:33pm – 4:46pm

Machine Learning Classification of Idiopathic Hypersomnia and Narcolepsy: Novel Clinical Predictors from a Decade-Long Urban Academic Sleep Center

NatalieDeana Badillo (United States)

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

O-28: Chronobiology and neurophysiology in early neurodegeneration

3:15pm – 4:45pm | Room 330

Chairs: Keisuke Suzuki (Japan), Angelica Quercia (Italy)

3:15pm – 3:25pm

Electroencephalographic slowing during REM sleep is a marker of cholinergic dysfunction in Lewy body disorders

Jack Anderson (Australia)

3:25pm – 3:35pm

Sleep Stage–Specific Aperiodic EEG Spectral Slope Alterations in isolated REM Sleep Behavior Disorder and Neurodegenerative Disorders

Jianzhang Ni (Hong Kong)

3:35pm – 3:45pm

Smartphone-based digital phenotyping of motor and non-motor biomarkers across early stages of α-synucleinopathies

Zhixuan He (Hong Kong)

3:45pm – 3:55pm

Circadian Clock Gene Per1/Per2 Knockout Leads to Motor Dysfunction in Mice

Yimei Fan (China)

3:55pm – 4:05pm

A diagnostic model for Parkinson’s disease based on circadian rhythm-related genes

Lufeng Wang (China)

4:05pm – 4:15pm

Effects of Light Therapy on Parkinson’s Disease–Related Brain Dysconnectivity and Sleep Disorders

Yun Shen (China)

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

SOMNOmedics: Next Era: Home Based Sleep Architecture and AI-Based PSG Scoring: Bridging Ambulatory and Laboratory Diagnostics

4:00pm – 4:45pm | Room 302

Artificial intelligence in sleep medicine - toward foundation models for polysomnography

Emmanuel Mignot (United States)

Presenting the DOMINO-AI from SOMNOmedics, certified by the AASM, and first clinical experience

Gert Küchler (Germany)

Longitudinal sleep assessment at home: A comparison of wearable and contactless approaches

Derk-Jan Dijk (United Kingdom)

HomeSleepTest – A Cost-Efficient and Innovative Tool for objective Sleep Stage Evaluation in the patients’ home

Hatem Khalil (Egypt)

Singapore Sleep Society Annual General Meeting 2025 Launch of the AMS Chapter of Sleep Medicine Physicians Obstructive Sleep Apnoea (OSA) Consensus Statements

4:45pm – 6:15pm | Room 303

Search the schedule, build your personal agenda, see the floor plans, and find more info in the official World Sleep 2025 app!

Supported by

SCAN TO DOWNLOAD THE WORLD SLEEP 2025 APP!

FRIDAY

September 5, 2025

SATURDAY September 6, 2025

SUNDAY September 7, 2025

Scientific Program | TUESDAY

Personalized management of OSA: AnatomicalPathological correlation, DISE integration, surgical modifications, and addressing CPAP and surgical failures

4:45pm – 6:15pm | Room 308

Chairs: Srinivas Kishore (India), Vikas Agrawal (India)

4:45pm – 4:50pm Introduction

Vijaya Krishnan (India)

4:50pm – 5:10pm

Bridging anatomy & pathophysiology: A unified perspective in OSA evaluation

Vikas Agrawal (India)

5:10pm – 5:30pm

Strategic use of DISE to enhance success rates in OSA surgery

Sandeep Bansal (India)

5:30pm – 5:50pm

Customized palatoplasty in sleep apnea: Matching surgical technique to airway phenotype

Vijaya Krishnan (India)

5:50pm – 6:10pm

When first-line treatments fail: Revisiting CPAP and surgical setbacks in OSA

Dipankar Datta (India)

6:10pm – 6:15pm Question and answer

Vijaya Krishnan (India)

Poster abstract group 3

4:45pm – 5:45pm | Hall 405

MONDAY September 8, 2025

TUESDAY September 9, 2025

WEDNESDAY September 10, 2025

Transforming Sleep Science with Wearable and Next Generation Technology: Samsung Opportunities and Case Studies

5:00pm – 6:00pm | Room 302

Chair: Eunyeon Joo (Korea, Republic of)

5:00pm – 5:15pm

Case Study Three: Reykjavik University

Objective and Subjective Sleep Experience: Comparing Smartwatch Tracking with Polysomnography and Digital Sleep Diaries

Luka Biedebach (Iceland)

5:15pm – 5:30pm

Case Study Four: Sungshin Women’s University

Sleep re-imagined: Insights from 60 million wearable users challenging what we know Sooyeon “Aly” Suh (Korea, Republic of)

5:30pm – 5:45pm

Case Study Five: Ilsan Paik Hospital

Mapping Sleep: Patterns Across BordersInsights from Samsung Galaxy Global Data