Vanders Human Physiology 15th Edition Widmaier Test Bank Chapter 1
Homeostasis: A Framework for Human Physiology
1) Which of these is NOT one of the four general categories of cells that make up the human body? A) Epithelial cells B) Collagen cells C) Connective tissue cells D) Neurons E) Muscle cells 2) Physiology is the study of A) how two organisms interact. B) how organisms function. C) the spread of diseases. D) the structure of the body. E) two of the choices are correct. 3) The study of disease states in the body is called A) pathophysiology. B) anatomy. C) homeostasis. D) differentiation. E) histology. 4) Which is NOT a connective tissue cell? A) Bone cell B) Skeletal muscle cell C) Blood cell D) Fat cell E) Cartilage cell 5) What is the principal function performed by epithelial cells? A) Fat storage B) Anchoring body structures C) Forming boundaries between body compartments D) Generating movement E) Transmitting electrical signals 6) The types of cells that are specialized to communicate with other cells and control their activities are A) epithelial cells. B) muscle cells. C) connective tissue cells. D) neurons. E) Two of the choices are correct.
7) What is the term for the developmental process that leads to specialized cell types? A) Genomics B) Differentiation C) Homeostasis D) Positive feedback E) Acclimatization 8) Which best describes the extracellular matrix? A) It is found just inside the cell membrane in all tissues, it sends branching collagen fibers between cells to connect them, and it transmits chemical information from the interior of one cell to the interior of adjacent cells. B) It is a tissue having more than the four general cell types, it transports proteins and polysaccharides between body compartments, and it is the route by which chemical signals like hormones reach all parts of the body. C) It covers the body's surface, it contains connective and muscle tissue, and it helps generate movement. D) It surrounds cells; it contains proteins, polysaccharides, and minerals; it provides a scaffold for cell attachment; and it transmits chemical messengers to cells. 9) If a person begins to sweat upon entering a hot room but continued sweating is able to keep the body temperature stable, which of these best describes her condition? A) She is in an equilibrium state. B) She is not using energy to maintain a constant temperature. C) She is in a steady state. D) She is using a positive feedback mechanism. E) Two of the choices are correct. 10) Which concept is the defining feature of the discipline of physiology? A) Descent with modification B) Homeostasis C) Evolution D) Equilibrium E) Differentiation 11) Describing a physiological variable as "homeostatic" means that it A) has varied from the normal value, and will remain constant at the new value. B) never varies from an exact set point value. C) is in an equilibrium state that requires no energy input to stay at the normal value. D) is in a state of dynamic constancy that is regulated to remain near a stable set point value. E) has no normal range, but will just change to match the outside environmental conditions.
12) Which of the following situations best represents a homeostatic mechanism? A) A person who becomes very nervous begins to sweat profusely. B) After going outside on a hot day, the core body temperature increases. C) Increasing the size of fast-food restaurant portions causes body weight to increase. D) After eating a large batch of salty popcorn, levels of salt in the urine increase. E) As age increases, the amount of calcium in bones tends to decrease. 13) What term is used to describe the steady-state value for any variable that the body attempts to maintain? A) Set point B) Equilibrium potential C) Error signal D) Reflex arc E) Median value 14) Which of components of a general reflex arc are listed in the order information typically flows through them following a stimulus? A) Effector, afferent pathway, integrating center, efferent pathway, receptor B) Effector, efferent pathway, integrating center, afferent pathway, receptor C) Integrating center, receptor, afferent pathway, efferent pathway, effector D) Receptor, efferent pathway, integrating center, afferent pathway, effector E) Receptor, afferent pathway, integrating center, efferent pathway, effector 15) Feedforward regulatory processes A) work in anticipation of changes in regulated variables. B) are identical to positive feedback processes. C) lead to instability of the regulated variable. D) maximize fluctuations in the regulated variable. E) tend to force physiological variables away from their set point. 16) Which situation describes a feedforward mechanism? A) Blood glucose returns toward normal an hour after a meal. B) The smell of rotten food on a plate triggers the vomit reflex. C) A drop in core body temperature triggers shivering. D) An increase in core body temperature stimulates sweating. E) Food in the stomach triggers the production of stomach acid. 17) What is the general purpose of positive feedback mechanisms? A) To maintain a constant internal environment B) To anticipate changes in the environment C) To return a variable toward the set point D) To bring about a rapid change in the body E) To detect changes in the external environment
18) Shivering in response to a cold draft is an example of A) a homeostatic mechanism. B) positive feedback. C) feedforward regulation. D) acclimation. E) Two of the choices are correct. 19) If the amount of sodium in the blood decreases, what would a negative feedback control mechanism be expected to do? A) Decrease the amount of sodium in the blood B) Increase the amount of sodium in the blood C) Leave the amount of sodium unchanged D) Change the set point for sodium E) Inhibit the ingestion of more sodium 20) What is the best description of the efferent pathway of a reflex arc? A) Signals from the integrating center to receptors B) The route by which receptors send signals to effectors C) Signaling pathway for receptors to influence the integrating center D) The route by which effector organs send signals to receptors E) The route by which signals from an integrating center reach effector organs 21) Which one of the following is the correct sequence for a regulatory reflex arc? A) Stimulus, effector, efferent pathway, integrating center, afferent pathway, receptor B) Stimulus, receptor, efferent pathway, integrating center, afferent pathway, effector C) Stimulus, receptor, afferent pathway, integrating center, efferent pathway, effector D) Stimulus, effector, afferent pathway, integrating center, efferent pathway, receptor E) Effector, efferent pathway, integrating center, afferent pathway, receptor, stimulus 22) Identify the effectors in this homeostatic reflex: Eating a salt-rich meal increases blood volume and pressure, stretching blood vessel walls. Nerve signals sent to the brainstem stimulate changes in hormonal and neural signaling. The heart rate is slowed, blood vessel walls are relaxed, and the kidneys increase urinary salt. The blood pressure returns toward normal. A) Brainstem and blood vessels B) Blood vessels, hormones, and nerves C) Heart, blood vessels, and kidneys D) Brainstem, blood vessels, and kidneys E) Hormones and nerves
23) The hormone insulin enhances the transport of glucose into body cells. Its secretion is controlled by a negative feedback system between the concentration of glucose in the blood and the cells that secrete insulin. Which of the following statements is most likely to be correct? A) A decrease in blood glucose concentration will stimulate insulin secretion, which will in turn lower the blood glucose concentration still further. B) An increase in blood glucose concentration will stimulate insulin secretion, which will in turn lower the blood glucose concentration. C) A decrease in blood glucose concentration will stimulate insulin secretion, which will in turn increase the blood glucose concentration. D) An increase in blood glucose concentration will stimulate insulin secretion, which will in turn increase the blood glucose concentration still further. 24) How are endocrine glands and hormones involved in homeostatic reflexes? A) Endocrine glands can be receptors, and hormones can be effectors. B) Endocrine glands can be integrating centers, and hormones can be efferent pathways. C) Endocrine glands can be efferent pathways, and hormones can be effectors. D) Endocrine glands are not part of reflex mechanisms, but hormones can be afferent or efferent pathways. E) They are not involved; reflexes only involve actions of the nervous system. 25) What is a hormone? A) A chemical released from a nerve cell that affects nearby cells across a synapse B) A chemical released from an endocrine gland that affects target cells without entering the bloodstream C) A chemical found in the blood that catalyzes the destruction of ingested toxins and foreign substances D) A chemical found in the sweat that signals other individuals about the physiological status of the body E) A chemical regulator secreted from an endocrine gland that travels through the bloodstream to affect target cells 26) Some neurons in the vagus nerve have synaptic connections to sinoatrial cells (pacemaker) in the heart. These neurons secrete acetylcholine, which ultimately results in a decreased heart rate. This is an example of A) endocrine control. B) exocrine control. C) hormonal control. D) neural control. E) paracrine control.
27) Heart rate is increased by the release of epinephrine by the adrenal medulla into the bloodstream. This is an example of A) endocrine control. B) exocrine control. C) paracrine control. D) direct neural control. E) positive feedback. 28) How is autocrine regulation best described? A) Chemical regulators are released directly into blood vessels. B) Chemical regulators released by cells affect the functional status of different kinds of cells in the vicinity of the secretory cell. C) Chemical regulators affect the same cells that produce them. D) Chemical regulators reach their site of action through a duct. E) Chemical regulators are continuously released in constant amounts by the cell. 29) The tall slender body shape that helps to dissipate heat in people native to equatorial regions is an example of A) an adaptation. B) acclimatization. C) set point resetting. D) homeostasis. E) phase shift. 30) After spending several days at a high altitude, where oxygen pressure is low, a person will begin to produce more red blood cells, which enhances the ability of blood to carry oxygen to the tissues. What term best describes this type of response? A) Developmental acclimatization B) Positive feedback C) Physiological acclimatization D) Feedforward regulation E) Evolution 31) Circadian rhythms are biological rhythms with what main characteristic? A) They are cyclical, like the 28-day female menstrual cycle. B) They are cyclical, like the rhythmic beating of the heart. C) They are voluntary rhythms, like the time you decide to eat lunch each day. D) They cease to occur when a person is in a dark environment. E) They repeat approximately every 24 hours, like daily spikes in hormone secretion. 32) What is the location of the internal pacemaker that sets biological rhythms? A) Suprachiasmatic nucleus of the brain B) Ventricles of the heart C) Endocrine gland in the gonads D) Photoreceptors of the eye E) The adrenal glands
33) A protein is found in blood that is produced by the pancreas and acts on receptors of cells in the liver. What type of physiological regulator is it most likely to be? A) A hormone B) An autocrine signal C) A paracrine signal D) A neurotransmitter E) An enzyme 34) Which best describes how the total body balance of any chemical substance is determined? A) The rate the body produces the substance B) The rate the substance is secreted from the body C) The rate the substance is metabolized by the body D) The difference between the amount of substance lost from the body and the amount gained the body E) The amount produced by the body minus the amount metabolized by the body 35) A burn patient ingests 100 grams of protein per day and loses 110 grams of protein per day due to the injury. What is the overall protein state of the patient? A) Positive protein balance B) Negative protein balance C) Stable protein balance D) A state that can't be determined 36) Eating a bag of salty potato chips without increasing sodium excretion would result in what state? A) Positive sodium balance B) Negative sodium balance C) Stable sodium balance D) It can't be determined without knowing the size of the sodium pool 37) An experimental subject is isolated in an underground room with no windows, no clocks, and no contact with the outside world. Researchers monitoring his behavior observe that he eats breakfast a little bit later each day. What term best describes the subject's biological activity? A) Circadian rhythm B) Free-running rhythm C) Jet lag D) Phase shift E) Entrainment 38) Which equation is most accurate? A) Extracellular fluid volume + interstitial fluid volume = whole body fluid volume B) Intracellular fluid volume + interstitial fluid volume = extracellular fluid volume C) Extracellular fluid volume - interstitial fluid volume = plasma volume D) Plasma volume + intracellular fluid volume = extracellular fluid volume E) Total body fluid volume - intracellular fluid volume = interstitial fluid volume
39) The internal environment of the body refers to A) the plasma. B) the interstitial fluid. C) the intracellular fluid. D) the interstitial fluid and the intracellular fluid combined. E) the plasma, the interstitial fluid, and the intracellular fluid combined. 40) The interstitial fluid refers to A) the fluid within the cells. B) the plasma. C) the fluid between the cells. D) the plasma and fluid between the cells. E) the fluid between the cells and the fluid within the cells. 41) Neglecting protein differences, which of the following fluids has a virtually identical solute concentration? A) The interstitial fluid and the intracellular fluid B) The interstitial fluid and the plasma C) The extracellular fluid and the plasma D) The interstitial fluid, the extracellular fluid, and the plasma E) None of these choices 42) When a blood vessel is injured, it releases chemicals that activate platelets and cause them to stick to the injury site. The activated platelets in turn release more chemicals and attract more platelets to the injury site until the wound is fully sealed. This process of blood clotting is an example of A) negative feedback. B) positive feedback. C) feedforward regulation. D) adaptation. E) acclimatization. 43) During childbirth, as a baby's head is pressed against the mother's cervix, signals are relayed via nerves from cervix to the mother's brain. The brain initiates the secretion of oxytocin (a hormone) from the mother's pituitary gland. Oxytocin stimulates further uterine contractions. As the uterus contracts even harder in response to oxytocin, the baby's head is pushed harder against the cervix; this stimulates yet more nerve signals to the mother's brain, resulting in yet more oxytocin secretion until finally the baby is pushed through the cervix. This process of childbirth is an example of A) negative feedback. B) positive feedback. C) feedforward regulation. D) adaptation. E) acclimatization.
44) During childbirth, as a baby's head is pressed against the mother's cervix, signals are relayed via nerves from cervix to the mother's brain. The brain initiates the secretion of oxytocin (a hormone) from the mother's pituitary gland. Oxytocin stimulates further uterine contractions. As the uterus contracts even harder in response to oxytocin, the baby's head is pushed harder against the cervix; this stimulates yet more nerve signals to the mother's brain, resulting in yet more oxytocin secretion until finally the baby is pushed through the cervix. The integrating center in this process of childbirth is A) the mother's brain. B) the mother's cervix. C) the nerve signals to the mother's brain. D) oxytocin. E) the mother's pituitary gland. 45) During childbirth, as a baby's head is pressed against the mother's cervix, signals are relayed via nerves from cervix to the mother's brain. The brain initiates the secretion of oxytocin (a hormone) from the mother's pituitary gland. Oxytocin stimulates further uterine contractions. As the uterus contracts even harder in response to oxytocin, the baby's head is pushed harder against the cervix; this stimulates yet more nerve signals to the mother's brain, resulting in yet more oxytocin secretion until finally the baby is pushed through the cervix. The effector in this process of childbirth is A) the mother's brain. B) the mother's cervix. C) the nerve signals to the mother's brain. D) oxytocin. E) the mother's pituitary gland. 46) During breastfeeding, as the baby suckles, nerve signals are relayed from the mother's nipple to the mother's brain. The brain initiates the mother's pituitary gland to produce more prolactin (a hormone), which causes more milk to be ejected. This process of breastfeeding is an example of A) negative feedback. B) positive feedback. C) feedforward regulation. D) adaptation. E) acclimatization. 47) Some adults have the ability to digest lactose in milk. This is an example of A) negative feedback. B) positive feedback. C) feedforward regulation. D) adaptation. E) None of the choices are correct.
48) As soon as a person sees a cup of lemon juice, they start to salivate. This is an example of A) negative feedback. B) positive feedback. C) feedforward regulation. D) adaptation. E) None of the choices are correct. 49) Differentiation is necessary before a cell can exchange material with its environment. 50) The number of distinct cell types in the human body is about twenty. 51) One function of epithelial cells is to form selective barriers regulating exchange of materials across them. 52) Organs are generally composed of only one kind of tissue. 53) The respiratory system is primarily responsible for transporting blood to the body's tissues. 54) Homeostasis refers to the relative constancy of the external environment. 55) The composition of the fluid bathing the cells of the body is the same as that within the cells. 56) The extracellular fluid compartment includes the interstitial fluid and plasma. 57) Homeostatic control systems and acclimatization are examples of biological adaptations. 58) A person who is acclimated to a hot environment will begin to react physiologically to a decreased environmental temperature faster than a person who is not. 59) When loss of a substance from the body exceeds gain, the body is said to be in positive balance for that substance. 60) The negative feedback system is much more common than the positive feedback system. 61) is the general term for a chemical released by the endings of neurons onto other neurons, muscle cells, or gland cells. 62) is the general term for a chemical released by the endings of neurons into the bloodstream. 63) cells.
regulation describes regulation of cellular activity by messengers from nearby
64) is the term describing regulation of cellular activity by chemical mediators produced by that same cell.
29) You're researching a steroid hormone that binds to a receptor inside the cell. Once the receptor binds to its hormone, the receptor moves into the nucleus of the cell. The result of hormone-receptor binding is that new mRNA molecules are made. The receptor is also a A) ribosome. B) transcription factor. C) tRNA molecule. D) promoter. E) splicosome. Answer: B Section: 03.05 Topic: Protein synthesis Bloom's: Level 3. Apply HAPS Topic: Module C10 Protein synthesis. HAPS Outcome: C10.02 Explain how and why RNA is synthesized. 30) Which is the best definition of the term ligand? A) A receptor composed of protein B) A molecule or ion that binds to a protein C) Any molecule found in the intracellular fluid D) Any molecule found in the extracellular fluid E) A carbohydrate molecule that binds weakly to membrane phospholipids Answer: B Section: 03.08 Topic: Protein synthesis Bloom's: Level 1. Remember HAPS Topic: Module C04 Organic compounds. HAPS Outcome: C04.04e Discuss physiological and structural roles in the human body of carbohydrates, proteins, lipids and nucleic acids. 31) Which is NOT true about a binding site on a protein? A) It is an area of the protein with a shape complementary to that of a ligand. B) It is determined by the amino acid sequence of the protein. C) The binding of a ligand to a binding site typically changes the conformation of the protein. D) There can only be one binding site on a given protein. E) Binding of a ligand to the binding site typically activates or inactivates a protein's specific function. Answer: D Section: 03.08 Topic: Protein synthesis Bloom's: Level 2. Understand HAPS Topic: Module C04 Organic compounds. HAPS Outcome: C04.04e Discuss physiological and structural roles in the human body of carbohydrates, proteins, lipids and nucleic acids. 13 Copyright 2019 © McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education.
32) A certain protein receptor is capable of binding the neurotransmitter epinephrine but does not bind to the neurotransmitters dopamine, glutamate, or serotonin. This is because the receptor displays what characteristic? A) Saturation B) Inhibition C) Specificity D) Acclimatization E) Accommodation Answer: C Section: 03.08 Topic: Protein synthesis Bloom's: Level 2. Understand HAPS Topic: Module C04 Organic compounds. HAPS Outcome: C04.04e Discuss physiological and structural roles in the human body of carbohydrates, proteins, lipids and nucleic acids. 33) A solution containing proteins of a particular type is exposed to the same concentrations of ligands X and Y, but the percent saturation of molecule X is greater than the percent saturation of molecule Y. Which is most likely to be a true statement? A) The binding sites for ligand X are 100% saturated. B) The binding sites for ligand X have greater specificity than the binding site for ligand Y. C) Ligand X must be a competitive inhibitor of ligand Y. D) Both ligands must bind to the same binding site on the protein. E) The protein has a higher affinity for ligand X than for ligand Y. Answer: E Section: 03.08 Topic: Protein synthesis Bloom's: Level 3. Apply HAPS Topic: Module C04 Organic compounds. HAPS Outcome: C04.04e Discuss physiological and structural roles in the human body of carbohydrates, proteins, lipids and nucleic acids.
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34) Tamoxifen is a breast-cancer drug that binds to the estrogen receptor. When in the body, tamoxifen binds to the estrogen receptor for much longer than the patient's own estrogen. Tamoxifen stays bound for so long that it prevents the binding of circulating estrogen to its receptor. Tamoxifen must have a higher for the estrogen receptor than estrogen. A) saturation B) inhibition C) specificity D) affinity E) accommodation Answer: D Section: 03.08 Topic: Organic compounds Bloom's: Level 3. Apply HAPS Topic: Module C04 Organic compounds. HAPS Outcome: C04.04e Discuss physiological and structural roles in the human body of carbohydrates, proteins, lipids and nucleic acids. 35) Two receptors, A and B, can bind the same chemical signaling molecules but the concentration of those molecules required to reach 50% saturation is twice as great for receptor B. Therefore, the receptors have the same , but different _. A) specificity; affinity B) specificity; saturation C) affinity; specificity D) affinity; competition E) competition; affinity Answer: A Section: 03.08 Topic: Organic compounds Bloom's: Level 3. Apply HAPS Topic: Module C04 Organic compounds. HAPS Outcome: C04.04e Discuss physiological and structural roles in the human body of carbohydrates, proteins, lipids and nucleic acids.
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36) Which describes the action of a ligand's competitive antagonist? A) It decreases the amount of ligand required to activate the protein. B) It blocks the binding of the ligand to its binding site and prevents activation of the protein. C) It binds to a different binding site on the protein, altering the protein shape so that a ligand cannot bind. D) When present, it increases the binding of a ligand to its receptor. Answer: B Section: 03.08 Topic: Organic compounds Bloom's: Level 2. Understand HAPS Topic: Module C04 Organic compounds. HAPS Outcome: C04.04e Discuss physiological and structural roles in the human body of carbohydrates, proteins, lipids and nucleic acids. 37) What is the defining characteristic of an allosteric protein? A) They contain two polypeptide chains, with each being an exact mirror image of the other. B) They contain only one ligand-binding site, but because the specificity is low, many different ligands can bind to it. C) They contain two ligand-binding sites, one that activates the protein when a ligand binds, and the other that inactivates the protein when the same ligand binds. D) They contain more than one ligand-binding site, and noncovalent binding of a ligand to one site alters the shape of other ligand-binding sites. E) They contain no binding sites of their own, but act by modulating the activity of other proteins. Answer: D Section: 03.09 Topic: Organic compounds Bloom's: Level 1. Remember HAPS Topic: Module C04 Organic compounds. HAPS Outcome: C04.04e Discuss physiological and structural roles in the human body of carbohydrates, proteins, lipids and nucleic acids.
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