Research Paper
Ayurveda
E-ISSN No : 2454-9916 | Volume : 8 | Issue : 8 | Aug 2022
THE CLINICAL STUDY ON A MINIMAL INVASIVE TREATMENT IN THE MANAGEMENT OF MUTRAASHMARIJANYA SHOOL w.s.r. RENAL CALCULI PAIN 1
Dr. Shattarka G Mahadik , Dr. Sheela S Kohad
2
1 2
Assistant Professor, Shalyatantra Dept., APM's Ayurved Mahavidyalaya, Sion. Associate Professor, Shalyatantra dept., APM's Ayurved Mahavidyalaya, Sion
ABSTRACT Renal calculi/calculus (Mutraashmari) is one of those ailments wherein one may have to cease all his daily duties instantaneously due to the pain. Not only that, once the calculi/calculus is formed & is not cured it keeps on giving bouts of pain, painful & burning micturition with or without hematuria. Many researches have been done in this area but the administration route being oral only. No much of the work is done in the treatment of Mutraashmari in the form of Basti (Enema). Hence an attempt to treat the Mutraashmarijanya Shool by giving Matra-basti of the Varunadi tailam as mentioned in the Bhaisjya-Ratnavali. The clinical study entitled “The Clinical Study on A Minimal Invasive Treatment In The Management Of Mutraashmarijanya Shoola w.s.r. Renal calculi pain”, was undertaken to discern and to understand the possible mechanism of action of an Matr-Basti of the medicated oil will exhibit and achieve an analgesic effect in the pacifying the Mutraashmarijanya Shool and whether will it be able to relieve the associated symptoms too. It won't be an exaggerated statement to make that, the task of taking Bastikarma in Mutraashmari especially to pacify the colicky pain as a topic for a clinical study was indeed a challenge to undertake. During this clinical study, the concept of Snehapak-kalpana, the various methods of drug standardization were implemented with the ideal ways of conducting and handling a clinical research work. KEYWORDS: Mutraashmari, Renal calculi/calculus, Mutraashmarijanya -Shool, Pain, Matra-basti, Varunadi Tailam. INTRODUCTION: In the Indian culture right from the time of our birth we unceasingly undergo the various 'Samskaras' and the 'Charyas' as preached by our Acharyas. These Samsakaras are actually meant for the natural body clock, ultimately for good health. Any attempt to breach in following these rules gives rise to diseases. This golden concept has been mentioned thousands of years back by our Acharyas. In today's time people are literally competing with the unstoppable Time and in doing so they fail to perform even small daily cores viz., micturition, defecation, oral hygiene, etc. Not taking care of the body, even if its excretory system signals (Adharneeya vega) for the expulsion of the urine and stools and suppressing the natural urges is seen on large scale in daily practice and illness is the obvious outcome to face. Suppressing micturition urge, not following Dinacharya, Ritucharya, excessive stress, intake of the various junk food & medicines causes renal system ailments. Renal calculus is one of those ailments whose pain could be at time so intense that one may have to cease all his daily duties instantaneously. Not only that, once the calculi/calculus is formed & is not cured it keeps on giving bouts of pain, painful & burning micturition with or without hematuria. Allopathy has many wonder drugs to kill the pain and associated symptoms immediately, just like the magical wand. But with all this, these drugs may also cause many side-effects ranging from hyperacidity to severe anaphylactic shock. Hence surgical intervention remains the only option in the hands of today's modern surgeons. All the Ayurvedic texts have mentioned multiple drugs compounds for the treatment of the Mutraashmari. Many researches have been done in this area but the administration route being oral only hence an attempt to treat the Mutraashmarijanya Shool by giving matra-basti of the Varunadi tailam, as mentioned in the Bhaisjya Ratnavali1. It is the vitiation of the vata-dosha that gives rise to the severe pain and bastikarma2 is considered the best treatment to control and pacify the vitiated vata-dosha and thereby alleviate the mutraashmarijanya Shool. While going through the texts, we find that in the purvarupa & rupa of the mutraashmari snehakarma is advised3, 4. Also in the Sushrut samhita it has been mentioned that the mutranirmiti (formation of the urine) takes place in the pakwashaaya5. Considering all the references the administration of the varunaditailam in Mutraashmari rogajanya Shool in the matra-basti should yield result. AIMS AND OBJECTIVES: 1. To clinically assess the Shoolaghna (analgesic) properties of Varunadi Tailam Matra-Basti 2.
To make an effective, cost effective, authentic, accessible conservative alternative or management ofMutraashmarijanya Shool.
3.
To observe and propose the possible mechanism of the action of the Varunadi-tailam Matra-Basti viz. Varuna (Crataeva nurvula), Gokshura (Tribulus terrestris) and Teel tailam (Oil of Sesamum indicum)
4.
To observe the side-effects & the complications of Varunadi-tailam Matrabasti, if any.
5.
To review the complete literature available on acute or chronic pain in Mutraashmari.
Materials and methods: The therapeutic use of Varunadi Tailam Matra-Basti in management of Mutraashmarijanya Shool; this yoga (formulation) has reference from the Bhaishjya-Ratnavali. An Open uncontrolled study was conducted in the OPD & IPD; at the Shalyatantra department of the concerned Hospital, after taking clearance from its Ethical Committee. An informed written consent was taken from all 30 the pts. in the language they well understood before commencing the trial. The pts. clinically diagnosed to have renal calculi/calculus and having at least two symptoms of the following–painful micturition, burning micturition & hematuria. The exclusion & the inclusion criteria of pts. of the study are given. All routine Haematogical investigations were done before starting the trial. Only TLC, DLC, RFT, Urine R. & Micro., X-ray KUB & USG-KUB were done both before and after to rule out any adverse effect of the therapy and also to see whether there was any effect on the size & number of the calculi/calculus; though a secondary finding. Following were the main criteria for the clinical assessment in this trial A) Local Pain B) Painful Micturition C) Burning Micturition D) Hematuria To assess the improvement in symptoms of gradations on the basis of severity & duration the changes in the gradations of the symptoms indicate the effect of trial drug. The effect of the therapy was assessed in terms of cured (100% relief), markedly improved (50-100% relief), improved (25-50% relief) and unchanged (25% to no relief). OBSERVATIONS & RESULTS: The data generated during the study can be grouped under 3 headings: A) Chemical Analysis of the drug used: Drug standardization (authentication of drugs, various analytical tests of the ingredients & the preparations were done at known and a standard pharmaceutical laboratories) was done as per the norms and recommendations, suggested by the CCRAS, Ministry of health & family welfare, New Delhi. B) Demographic Analysis: Here the pts. analysed with respect to various parameters of the Demography (age, sex, religion, education, occupation, marital status, etc) in the form of tables & graphs are mentioned. C) Clinical efficacy of drug after completion of the therapy was shown as the % of relief observed in pts. for the particular symptoms. Also the duration of time needed to achieve the relief was shown in form of tables and by applying appropriate Statistical analysis. Wilcoxon-matched- pairs-signed-ranks test was applied to the total symptom score which was seen to highly significant.
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International Education & Research Journal [IERJ]
66