FIRSTLO is revolutionizing the entire Bio-coldchain logistics process with blockchain and AI Tech
This catalog ditails FIRSTLO’s Core Technologies & Vlues, divided into 7 sections
Introducing the FIRSTLO brand and analyzing the challenges & crises in the coldchain market
Integrated technology architecture and details on core technologies such as AI, Blockchain, AIoT
Introducing the key features- function dashboard, center monitoring and shipment tracking
with the Pharmaceutical Distribution Management
01
Background & Necessity
Vulnerabilities in the Modern Pharmaceutical Supply Chain
The significant LOSSES and IMPACT on PATIENT SAFETY caused by Coldchain Logistics Failures, and FIRSTLO’s approach to addressing them
1.An Invisible Crisis
the Ripple Effects of Coldchain Failures in Modern Medicine
A Hidden Vulnerability in Modern Medicine $35 Billion
Vaccines, Insulin and Advanced Cancer Treatments are Extremely TEMPERATURE-SENSITIVE Biopharmaceuticals.
Maintaining a “Coldchain” from production to delivery to patients is not simply a recommendation ; It’s a “MANDATORY REQUIREMENT” to ensure SAFETY & EFFICACY. Worlwide, approximately $35 billion in bioproducts are lost each year due to IMPROPER TEMPERATURE MANAGEMENT. This LOSS goes beyond Financial loss and posses a Direct Threat to PATIENT SAFETY.
Patient Safety Threats
Adiministration of medications with Reduced Efficacy, Delays in Treatment & Compromised Drug Safety can seriously threaten a patient’s health and can even lead to life-threatening sitautions, especially for patients with sereve illness
2.Ripple Effect
More than just Financial Loss
The Ripple Effect of Coldchain FAILURE
The direct financial loss of $35 billion is just the tip of the iceburg. Serious Implications caused by Coldchain Management Failures are Patient Safety, Corporate Credibility, the Environment, and Regulatory Compliance.
① Patient Sefety Threats
Patients face ineffective medications or potentially life-threatening treatment delays.
The efficacy of temperature-sensitive biopharmaceuticals declines directly impact patient outcomes.
② Declining Trust
Healthcare Providers & Patients are losing trust in the Supply chain, demaging brand reputations. Uncertainty about drug quality is undermining the trust relationship between patients, doctors, and pharmaceutical companies
③ Environmental Waste
All resources used in discarded pharmaceutical yarn are watred, burdening the environment
Discarded pharmaceuticals due to temperature fluctuations significantly increase Carbon Footprint
④ Regulatory Penalties
Failure to coomply with stringent GDP regulaions can result in significant Fines & Sanctions
Failure to comply with audits by global regulatory like the FDA & EMA poses a Serious Business RISK
Key Failure Points
Vulnerabilities & Risk Factors in Clodchain
Vulnerability Analysis of Coldchain Supply Chain
The risk of Temperature Deviations significantly increcases at Specific Points throughout the Coldchain Logistics Process.
Product integrity is treatened at Handoff Points, Customs Inspection Areas, and Long-distance Delivery
FIRSTLO monitors these KEY VULNERABILITIES in Real Time to proactively prevent risks.
Place of Production
Biopharmaceutical Production & Packaging stages.
Temperature logger installation and initialization just before shipment
Land Transport
Transport inf refrigerated/freezer vehicle poses a high risk possiblity due to changes in vehicle conditions, equipment problems, delays caused by traffic conditions
Airport Cargo
High risk of temperature deviation during Storage & Handing Area prior to loading as air cargo, Loading and Customs Inspection. Particularly during the Cargo Handover Process, where responsibility Shifts
Air Transport
When transporting long distance via international air, thera are risks in case of emergency situations & delays regardless of the cargo compartment temperature
Import Airport
Difficulty Maintaining Temperature druing
Unloading, Customs Clearance, Quarantine, Customs Procedures & Opening Inspection at the arrival Airport
Last Mile Delivery
High Risk of Temperature Deviation due to delivery route to final destination (hospital/pharmacy), traffic congestion, frequent stops & door opening, instability of temperature management systemsin personal delivery vehicles
Fast-growing Industries & Opportunities
Explosive Growth in the Coldchain Market
The Global Biopharmaceutical Coldchain Market is projected to grow from $18.2 billion (in 2024) to $51.6 billion (in 2034) at a STEEP COMPOUND annual growth rate of 10.98%
This growh is increasing the need for more Advanced Technological Management Solutioins!
Market Growh Rate
The global coldchain market is projected to grow approximately 2.8-fold over the next decade, driven in particular by the rise of biopharmaceuticals, vaccines, and cell & gene therapies.
Growh Drivers
1. Rapid growh of the Biopharmaceutical Market
2. Increase in temperature-sensitive products
3. Tightening Regulations (GDP, DSCSA)
4. Increasing Complexity of the global supply chain
$51.58B (2034)
Annual Losses due to Coldchain Failures are approximately $35 billion Effective Coldchain Management can reduce these losses and improve profitability & efficienty in pharmaceutical industry
$18.23B → $51.58B
02
Solultion & Architecture
Integrated Technology Architecture and Details of core AI, Blockchain, AIoT Technologies
The Most Reliable Solution for AI-Coldchain Logistics with Blockchain
An Innovative Coldchain Solution can Prevent $35 billion in Annual Losses
End-to-End Visibility-Based Coldchain: Stopping $35 billion in Annual Losses
“Production→Storage→Transportation→Delivery” A Single Platform provides Real-Time, Reliable Data Blockchain Technology provides immutable data records and AI based predictive systems
4-Pillar Sollution
Storage Managing
Supports Wireless Installaion
Real-time temperature &humidity monitoring
Manage the Space-based device
Delivery Managing
Full-range
location/environmnet tracking
Immediate departure notification
Real-time temperature/humidity recording
AI System
Preemptive temperature deviation prediction response notifications(SMS/App)
Real-time chatbot support
Anti-Tampering Traceability Regulatory Compliance Support Blockchain
Good Distribution Practice -the 4 core requirements
The 4 Core Requirements of the GDP for Pharmaceuticals
GDP(Good Distribution Practice) is a quality assurance guideline governing the transport, storage and handling of pharmaceuticals - Complicance is required by Global Regulatory Authorities (FDA, EMA, WHO) The 4 Core Priinciples ensure Patient Safetu and Product Integrity.
① Temperature Control
Pharmacurticals must be stored and transported within specified temperature range (e.g., 2°C ~ 8°C)
Temperature Deviations directly affect product quality & efficacy so, Continuous Monitoring and Control are essential
Key Regulations
② Verified Equipment
All Equipment used in the coldchain (refrigerated vehicles, data loggers, temperature-controlled warehouses etc.) must be validated and regularly calibrated. Equipment reliability is fundamental to Data Accuracy.
Key Regulations
③ Monitoring & Documentation ④ Risk Management
Continuous Temperature Monitoring & Audit Trails are essential throughout the Supply Chain.
Appropriate Documentation is required to ensure Transparency and Traceability.
Regulations
Identifying Potential Risks (such as temperature deviations) that may occur in the Supply Chain, Implenemtin corrective , preventive actions (CAPA) to mitigate them is essential. Proactive Risk Management, not reactive is crucial
Key Regulations
FIRSTLO Solution Architecture
An Integrated End-to-End Platform
Unified Architecture Structure
Based on an integrited AIoT platform, FIRSTLO securely records data collected from IoT sensors in a blockchain-based Temperature Controlled Logistics System (TCLS). This system ensures the integrity of temperature and location data throughout the entire process, from production to logistics and final delivery, enabling global control
Control Layer
Global Control
International logistics route tracking and cross-border link monitoring
Business Module
Tracking Management
Delivery Scheduling, Reproting and Insight Analytics
Domestic Control
Integrated control of domestic transportation networks
TCLS Service Platform
Management
User Management, Permission Settings and System Preferences
Blockchain-based TCLS
Blockchain Data Platform
Cryptographic Hashes, Timestamps, and Immutable Data Storage based on a Distributed Ledger
Temperature Sensor
2~8°C Precision Monitoring
Logistics Center Control
Real-time Environmental Control within logistics center and warehouses
Control
Sensor Settings, Alert Thresholds and Remote Command Control
Data Sharing & Synchronization
ERP Iintegration, API Interface and External System Data Synchronization
Information Collection
Humidity Sensor
Location Tracking (LBS)
End-to-End Process
Package Sensor
Opening Detection
Core Tech 1 | AI Technology
Predict & Prevent Temperature Deviations with AI
AI-Based Pre-Prediction Technology
FIRSTLO’s AI technology analyzes Past Data Patterns to predict future temperature deviations and enable proactive responses before problems occur
Traditional Method : Post-Response
An Alarm Triggered after the temperature has already exceeded the allowabel range, preventing product damage
Machine Learning-based Pattern Analysis
By learning from thousands of Ligistics data sets, we identify anomalies and predict temperature change patterns
AI Method : Pre-Prediction
Preventative Measures to Prevent Product Damage by analyzing temperature change patterns we can proactivelly detect deviation risks
Real-time Risk Assessment
By analyzing various factors, including environmental data, routes, historical patterns we calculate risk in real time
Instant Notification System
When a risk is detected, the person in charge is immediately notified via SMS, ARS or App Push Notifications
Core Tech 2 | Bockchain (Immutable Trust)
Ensuring Data Reliabilitiy with Blockchain
The Value of Blockchain Technology
Blockchain can solve the core problem of “Data Reliability” in biopharmaceutical logistics through “Distributed ledger Technology.” It ensures the integrity and traceability of temperature data through Harsh Algorithms and Timestamps.
Immutability
Once Recorded Data cannot be tempered with, Blockchain’s distributed ledger technology invalidates all attemps to alter data, ensuring 100% data reliability.
Transparency
All participants SHARE the SAME INFORMATION. By ensuring real-time visibility of logistics statue and temperature data throughout the supply chain. We address information asymmetry.
Audit Trail
All transactions and data changes arre recorded with a timestamp. This ensures complete tracking of WHEN, WHERE, WHO and WHAT actions were taken
GDP Compliance
Blockchain technology fully meets the core requirements of the GDP for Pharmaceuticals DOCUMENTATION & TRACEABILITY
It provides evidence that can be immediately addressed in regulatory audits.
Blockchain Platform Performance Comparison
Differences Between Hybrid Public Blockchain and Existing Blockchain Technologies
Block Generation Speed (sec.)
Delivery information blockchain recording time (sec.)
Event notification time delay
Data
Horizontal scalability with high-performance servers
- Network Access Control (Access restricted to authorized users only)
- Limited Integrity (Operator-Centric)
30sec.
* Recording time delayed due to ‘HOOK’ occurrence
Decentralized structure limits scalability when nodes increase.
- Use advanced features
- Data capacity limitations
- Not suitable for storing sensitive information
- Decentralization slows decision-making
- Accessible to all users
- Impossible to forge or alter
Secure “Local + Global” scalability
- Contract Management (DB)
- Data Verification Records (Public)
- On-chain/DB Separate Storage
- Only important records are stored publicly
- Participation of all logistics stakeholders (manufacturers, transport companies, hospitals, individuals, etc.)
- Participatory governance design
- Restricting sensitive information access.
- Only DID-based identifiers are disclosed.
- Sensor data is stored in a highly available database.
- Hashes are publicly recorded to ensure data traceability.
- Robust tamper-proofin
- Auditing within a closed network is difficult
- Audit records can be manipulate
- Ensuring immutability and transparency of records
- Real-time monitoring + public records make it easy to respond to audits by the Ministry of Food and Drug Safety, end users, etc.
AIoT Sensor System
Real-time
Data Collection and Processing FLow
AIoT Integrated Sensor Network
FIRSTLO collects temperature, humidity, and location information in real-time using HIGH-PRECISION IoT Sensors This information is securely recorded on the blockchain-based TCLS plarforms.
By Monitoring the entire process in real-time, FIRSTLO ensures complete pharmaceutical quality and proactively prevnets temperature deviations through real-time notifications and predictive algorithms.
Real-time Monitoring
Temperature, Humidity, Location, Light and Shock data are collected in real time at 30-seconds intervals, and immediate notifications are provided when abnormalities are detected
2-8°C Temperature Control
Strictly maintain the Optimal Temperature range (2-8°C) for biopharmeceuticals Monitor to prevent quality degradation
Blockchain-based Recording
All Collected Data is recorded on a tamper-proof blockchain ledger, enabling GDP compliance and audit trails
4 Major Solution Pillar
4 Core Solution Components of FIRSTLO
Storage Management
Real-time Temperature & Humidity Monitoring
: Distributed IoT sensor network for 24/7 warehouse environment monitoring
Automated Inventory Tracking
: Location based real-time inventory tracking & optimization of optimal storage locations
Digital Twin Visualization
: Remotely Monitor & Control your warehouse facilities with a Digital Replica
Transportation Management
Global Tracking System
: Real-time Location Tracking for all domestic & international shipping routes
Environmental Condition Logging
: Automatically records temperature, humidity, shock, and light exposure data through the entire transport period
Route Optimization
: Automatically optimizes transportation routes considering lead time, cost and risk factors
AI System
Temperature Excursion Prediction
: Machine Learning-based Temperature Pattern Analysis to Predict Excursion Risk
Preemptive Alarm System
: Automatic SMS/ARS alers and action recommendations when a risk is detected
LLM based chatbot
: an Intelligent Assistant for user inquiry response and operational support
Blockchain Data Management
Immutable Data Ledger
: Ensures the Integrity of the entirre supply chain with immutable records
Smart Contracts
: Contract Protocols that automatically execute when specific conditions are met
GDP Compliance
: Meet regulatory requirements with auditable documentation
FNC 01 | Secure Login
Safe & Convenient User Authentication System
Secure Authentication and Access Management
The FIRSTLO platform feaures a login system that perfectly balances security and user convenience. Differentiated access management based on user permissons & Multiple security policies ensure the secure protection of biopharmaceutical data.
Security Authentication System
ID/PW-based Security Authentication Role-based Access Control (RBAC) ensure only the features appropriate for user permissions are provided
Multi Platform Support
Access the same account on both Web Browsers & Mobile Apps Your Activity history is synchronized in real time
Login Function Details
Security Authentication System Enforce a Strong Password Policy
Convenience Features
Offer features that prioritize both user convenience and security, including device storate options, password reset & automatic logout
Autojmatic Login Security Token-based Auto-login option, Lasting up to 30 days (user selectable)
Account Protection Account is locked after 5 or more failed login attempts etc..
Account Hierarchy Provides customized access rights and inerfaces for each role
Access Log Log and Monitor all login attempts, IP addresses, device information etc..
Data Encryption HTTPS communication & AES-256 encryption for sensitive information
Balance of Security and Convenience
Principle of Least Privilege
It’s designed to provied access only to the minimum functions and data necessary for your work, protecting the system from internal threats.
EASY Accessibility
While maintaining security, the intuitive UI and device storage options provice quick access for field users
FNK 02 | Main Dashboard (UI)
An Integrated Dashboard that provides an overview of the entire system at a glance
FNC 02 | Main Dashboard (Functional Decomposition)
Analysis of the Core Functions of the integrated control interfere
Intuitive Dashboard System
FIRSTLO Platform is designed to provide a Comprehensive Overview of all key coldchain operations. from Real-time Data Visualization to Detailed Analysis Tools, it empowers operators to make quick & efficient decisions
Real-time Monitoring
Provides real-time visualization of temperature, humidity & location data
Real-time Monitoring
Alert Management
Data Analysis
Documentation
User Management
System Settings
Alert Management
Provides immediate notifications when critical events, such as temperature deviations occur
Data Analysis
Trend Analysis & Risk Prediction based on cumulative data Documentation
Automatically generate customized reports and export documents
Dashboard Core Features Details
· Strong Passwerd Policy (minimum 8 characters, a combination of special characers etc..)
· Filtering and Grouping by Center, Device and delivery
· Color Coding by Status (normal: green, caution: yellow, warning: red)
· Set notifications for events such as temperature deviations, humidity changes and communication errors
· Multi-channel Notifications, including SMS, E-mail, App Push notifications and system alerts
· Notification history management and resolution status tracking
· HIstorical data-based trend graps and statistical analysis
· AI-based prediction algorithms to predict temperature deciations
· Performance comparison analysis by segment, device, and time zone
· Automated report generation for GDP compliance verification
· Export documents in various formats, including PDF, Excel, CSV
· Custom Dashboard Layouts and Settings for each user
· Multi-access management and user activity logging
· System Settings such as notification thresholds and automatic report schedules
· Data retention policies and backup configuration
· API integration and integrated management with external systems (such as ERP)
Dashboard Core Components
KPI Summary Panel
Key Metrics, including total deliveries, devices, centers and notifications are presented in CARD FORMAT
Interactive Map
Visualize Global Logistics Locations on a map and ZOOM in/out to specific areas
Real-time List
Displays current deliveries, activated devices, and recent notifications in real time
Center Monitoring (Digital Twin)
Real-time 3D Facility Monitoring & Temperature Management System
Digital Twin-Based Real-Time Monitoring
Visualize Device Placement based on drawing uploads and layouts. Adjust device positions with drag-and-drop. Temperature Information for each device is updated in real-time.
Temperature heatmaps allow you to intuitively view temperature distribution throughout the space.
FNC 03 | Center Detail Data
Detailed Analysis of Logistics Center Environmnet & Device Information
Center Information & Environmental Data Dashboard
Provides a dashboard for intuitive access to detailed information & real-time environmnetal data for each center. Monitors critical facility information, as well as environmental data such as temperature, humidity, pressure, vibration, and illuminance in real-time, and immediately detects any abnormalities.
Center Basic Information
Name Osong Bio Logistics Center (BC-OS-001)
Location CBIST (Osong, Chungbuk)
Area 3,250㎡
Start of operation March 15, 2023
Storage capacity
55,000 pallets (up to 8,500 bio products)
* This dashboard is provided as an example for corporate security and privacy consent purposes.
TH-OS1-023
TH-OS1-045
PR-OS1-012
VB-OS1-008
connection
06:54
23:27
15:32
FNC 04 | Device List
Integrated Management & Monitoring of IoT Sensor Assets
Device Management & Status Monitoring
View the List & Status of all sensor devices registered on the FIRSTLO platform at a glance
Key information, including each device’s Unique ID, Type, Status, most recent Data Update Time, and Remaining Battery Life is summarized for Quick Visibility into the operational status of your entire device portfolio.
Search & Filter
Quickly Search & Filter by various criteria including device ID, type and status
Register / Delete Device
Flexible Asset Management including new equipment registration and deletion of unnecessary euqipment
Real-time Satus Updates
All Device Statuses are Automatically Updated every 30 Seconds and manual refresh is also possible
Device Management Policy
Automatic Status Check
If the battery level falls below 20% or the device is unplugged for more than 30 minutes, it will automatically enter an alert state.
Automatic Filtering of Account Linking
Only devices registered to your user account are displayed, and only assets within your permission scope can be managed
Coldchain Loss Analysis & the FIRSTLO Effect
Coldchain Crisis (Problem) FIRSTLO Solution
$35B/yrs Loss : Caused by a Combination of Temperature Fluctuations, Logistics Delays etc..
Direct losses due to discarded expensive medicines such as vaccines, insulin, anticancer drugs, and indirect losses due to delayed patient treatment.
Location & Context Disconnection
Simple temperature data alone makes it impossible to determine responsibility. The lack of context regarding the precise timing & location of environmental changes makes post-event management difficult
The transition process between multiple entities creates a high risk of temperature deviations and GDP regulation violations. A “Gray Area” exists where responsibility is unclear
Coldchain Crisis
Unified Platform : A Digital Twin Mapped 1:1 with Physical Flow
Build Context-Preserved Data by providing real-time, end-to-end visibility across the entire production-storage-transport-acquisition process
Predictive AI : Advance Warning of Future Temperature Excursions
By learning from past data, we can predict temperature deviations, provide operators with advance warnings and opportunities for on-the-go problem resolution
Immutable Data: Full History Recorded on the blockchain
Records management that cannot be tampered with based on timestamps & hashes. Build trust through auditability, regulatory coompliance, claeraccountability
Advanced Real-Time Tracking & Blockchain Record Management Capabilities Maximize Coldchain Logistics Visibility and Reliability Tracking Shipment Real-time Inquiry System Blockchain Record Verification
Track & Manage Shipment History
Real-time Location Tracking & Environmental Condition Monitoring System
Blockchain Record Inquiry System
The FIRSTLO blockchain Encrypts and Stores all coldcahin data and ensures that information cannot be altered once recorded. This provides a complete audit trail for GDP coompliance.
Transaction Details
Transaction ID: 0xe45a8b7c9d3f2a16
Timestamp 2025-11-12 14:35:22 (UTC+9)
Delivery ID SHP-20251112-0037
Data
GDP Authentication Satus
04
AI - Intelligence
Making the Coldchain Smarter with AI. Maximizing Logistics Operational Efficiency with Predictive Systems & Natural Language Conversational Assistants.
Prediction System LLM Chat Bot
Machine learning-based temperature excursion prediction prevents product loss.
System control &information retrieval through a natural language-based conversational interface
Core TECH. 1 | AI - Prediction System Details
FIRSTLO AI Technology Predicts Temperature Deviations in advance using Proactive Machine Learning
Predictive AI Algorithm Technology
Analyze Massive Amounts of Coldchain Data, Predict Temperature Deviations in advance, and, unlike conventional reactive systems, Take Proactive Measures before problems occur. Reduce Product Loss.
Machine Learning-Based Temperature Excursion Prediction
Advanced Machine Learning Algorithms learn from a Variety of Data including temperature, humidity, ambient conditions, and transportation routes to protect temperature deviations up to 12 hours in advance
Pattern Analysis and Learning
a Self-Learning System that continuously improves accuracy be analyzing historical transportation data, seasonal patterns, regional characteristics and patterns by delivery type
Anomaly Detection
Detects subtle changes & abnormal patterns from sensor data collected in real-time, generating early warnings when trends are heading in a dangerous direction, even if they are withing standard limits
Business Benefits
① Minimize product loss and reduce costs through
② Reduce patient safety risks and ensure drug efficacy
③ Automating GDP compliance and improving risk management
Core TECH. 2 | AI LLM Chat Bot
Natural Language-Based Intelligent Conversation System
FIRSTLO AI Chat Bot - Intelligent Assistant for Coldchain Logistics
Users can ask questions to the system in natural language, check GDP regulations, and track delivery status in real time without complex menu structures.
An AI engine based on a large language model (LLM) understands the context and provides accurate answers and recommended actions.
Core TECH. 3 | Business Platform Application Technology
ntroduction to Business Platform Application Technology
AIoT Integrated Platform Architecture
Securing quality and visibility across all sections with blockchain-based TCLS on an integrated AIoT platform. Synchronizing with external ERP/data, unifying central, domestic, and global control.
Implementing an end-to-end integrated architecture, from data collection to AI-based transportation quality managemen
AIoT Integrated Platform
TCLS
Data Platform
Control and Management
End-to-End Process Flow
05
GDP Compliance Solutions
Introducing FIRSTLO's cutting-edge solution, which fully meets the four core principles of the Good Distribution Practices (GDP) through blockchain and AI technologies. It innovatively addresses regulatory requirements for temperature control, equipment verification, documentation, and risk management.
GDP Solution Mapping
Seamless Integration of FIRSTLO Technology & GDP Requirements
The 4 Principles of GDP & FIRSTLO Solution
Discover FIRSTLO's innovative technology solutions, which fully address the four core requirements of Good Distribution Practice (GDP). Each requirement is mapped to a specialized technology, ensuring complete compliance with pharmaceutical management regulations.
Temperature Management
Pharmaceuticals must be stored and transported within the manufacturer's specified temperature range. Any temperature deviations must be immediately detected and recorded.
AIoT Sensor Network
Real-time temperature monitoring, automatic notifications, and precision temperature data logging (±0.2°C)
Equip Verification
All equipment used in the coldchain (refrigeration equipment, temperature recorders, etc.) must be validated and regularly calibrated.
Blockchain Authentication System
Encrypted storage of equipment verification records, tamper-proof calibration history, and digital certificates
Documentation
Detailed documentation of all activities is required to ensure transparency & traceability throughout the supply chain.
Automatic Report Generation
Automatically record real-time data, generate PDF/Excel documents, and automate audit-ready reports.
Risk management
Potential hazards (e.g., temperature deviations) must be identified & corrective, preventive actions (CAPA) implemented to mitigate them.
AI Prediction Algorithm
Predictive temperature deviations, pattern analysis-based risk assessment, and automated preventive action system
GDP Temperature Management Solutions
Temperature management requirements and FIRSTLO's technical solutions
Requirements of GDP Temperature Management
Temperature control is a core requirement of Good Distribution Practice (GDP), and strict temperature conditions must be maintained to ensure the efficacy & safety of biopharmaceuticals.
2-8°C Maintain Strict Temperature Range
Biopharmaceuticals must be stored and transported within the manufacturer's specified temperature range (typically 2-8°C). Exceeding this temperature range may result in reduced efficacy or safety issues.
Real-time Temperature Monitoring
Continuous temperature monitoring is required throughout the supply chain to ensure that products are maintained at appropriate temperature conditions at every stage.
FIRSTLO SOLUTIOIN
AIoT Sensor Network
High-precision temperature sensors are deployed throughout the logistics chain to collect real-time environmental data. Temperatures are monitored 24/7 at all locations, including logistics centers, transport vehicles, and storage facilities.
Real-time Temperature Graph
Collected data is visualized in intuitive graphs, allowing you to understand the product's condition at a glance. Temperature analysis - early detection of potential problems.
Automatic Alarm System
Immediate Alarm
If the temperature exceeds the specified range, an immediate notification must be sent to the responsible person. Prompt action must be taken to minimize product damage and prevent quality issues.
Safe temperature range for biopharmaceuticals
When temperatures begin to deviate from safe ranges, the AI predictive system proactively detects potential deviations and immediately alerts via SMS, email, or app notifications.
GDP Automated Compliance Documentation
All temperature data is recorded on the blockchain, enabling audit trails. Standard GDP reports, ready for submission to regulatory authorities, are automatically generated.
GDP Documentation & Audit Trail
Automated Documentation System for Regulatory Compliance
GDP Documentation Requirements & FIRSTLO Solutions
GDP requires rigorous documentation and audit trails throughout the pharmaceutical distribution process. FIRSTLO leverages blockchain technology to automate these requirements and provide an immutable audit trail system.
GDP Documentation Requirements
Delivery Record Management
All biopharmaceuticals must be documented for traceability, including the origin, transit, destination, contact person, and transit time
Temperature log
Temperature conditions for cold chain products must be recorded throughout the entire distribution process, & any deviations must be documented in detail and corrective action taken.
Equipment Verification Certificate
Verification records and calibration documentation must be maintained for cold chain equipment, including sensors and refrigeration units.
Incident Reporting & Departure Management
In the event of a GDP deviation, the incident history, cause analysis, corrective actions, and measures to prevent recurrence must be documented in detail.
FIRSTLO Automation Solutions
Blockchain-based records
All shipping data is automatically recorded on the blockchain, making it impossible to satisfy and permanantly preserved.
Real-time delivery tracking
The entire delivery process is automatically recorded and visually confirmed based on GPS and BLS
Real-time temperature data logging
Temperature data collected by AIoT sensors is recorded every minute and stored on the blockchain.
Automatically detect and record departures
Automatically records the time, location, and degree of deviation when a temperature deviation occurs, and documents the actions taken.
Digital Verification Certificate
Digitize and link verification documentation for all sensors and equipment to the blockchain for traceability.
Automatic validation
Automatically manage equipment validation expiration dates and provide revalidation notifications.
Automatic report generation
Automatically drafts incident reports when a deviation occurs and provides them for manager review.
PDF/Excel Output
Support for exporting documents in standard formats for regulatory submissions
Blockchain Audit Trail
immutability
Once GDP is recorded on the blockchain, the documented data cannot be altered, ensuring the trust of regulatory authorities.
Timestamp
Ease of auditing
All
Block
Media Hub
Check Out the Video Footage & Live Operational Demo of the FIRSTLO platform.
This vivid Demonstration Shows the Coldchain Monitoring System & Blockchain-Based Rracking Technology in action.
FIRSTLO Platform Value Proposition
Core Values and Performance Indicators for Biopharmaceutical Cold Chain Management
FIRSTLO Platform Core Values
The FIRSTLO platform integrates blockchain, AIoT, and AI technologies to innovatively improve the cold chain management of temperature -sensitive biopharmaceuticals. This delivers the following core values.
Cost Savings
Minimize product loss and optimize inventory management, reducing operating costs by up to 35%. Prevent additional costs with proactive management using AI predictive systems.
Regulatory Compliance
Automating temperature management, equipment validation, documentation, and risk management in accordance with GDP requirements increases regulatory compliance & reduces audit time and costs..
Tranparency
Using blockchain technology, an immutable data ledger transparently manages pharmaceutical temperature history and distribution processes, providing a reliable audit trail.
Efficiency
Increase operational efficiency through real-time monitoring, automated alerting, and intuitive dashboards, and optimize operational processes with data-driven decision-making.
Loss Reduction Rate
68%
Before system introduction
After system introduction
After implementing the FIRSTLO platform, product loss was reduced by 68%.
"Temperature deviation incidents were significantly reduced, saving over 300 million won in annual drug disposal costs.."
System Availability
99.8%
Optimized cloud infrastructure and redundant design ensure stable service.
"With 24/7/365 uninterrupted monitoring, you can rest assured in any situation.."
User satisfaction
92%
Unsatisfied
Achieving high user satisfaction through user-centered design & intuitive UI/UX
"Complex data can be viewed at a glance, and work time is reduced by more than half." Satisfied
The Meaning & Necessity of Coldchain
The Importance of Coldchain for the Safety & Efficacy of Biopharmaceuticals
Introduction to the Concept & Importance of Coldchain
This viedo introduces the Definition, Industrial Necessity, and Key Characteristics of the Coldchain for Biopharmaceuticals. It provides an easy-to-understand explanation of the components and components and importance of a coldchain logistics system to ensure the quality of temperature-sensitive pharmaceuticals.
Coldchain Training Video
Scan the QR code to watch a detailed video on your mobile device explaining the definition and necessity of cold chain. This video explains why cold chain is necessary for biopharmaceuticals, how temperature management affects product quality and efficacy, and the key elements for compliance with global GDP regulations. It provides essential fundamental knowledge for pharmaceutical industry and logistics professionals.
FIRSTLO’s Dashboard is an integrated control system that monitors all stages of biopharmaceutical coldchain logistics in real-time. The user-friendly ingerface allows you to view temerature, humidity nad location data at a glance and immediately detect any abnormalities.
Real-time Temperature & Humidity
Monitoring and
Alert System
Visualizing Space Management with Center/Warehouse Digital Twin Tech
Cross-platform Mobile/desktop support and real-time notifications
Cooperation in building verification infrastructure Local Government Supporting Org.
Regional Characteristics & Synergy
Strategic Integration of Chungbuk Osong Bio Cluster and Incheon IFEZ
Osong Bio Cluster in Chungbuk
The Osong Bio Cluster in Chungbuk is Korea's largest bio-industry cluster & a key base for the FIRSTLO. High concentration of cutting-edge R&D facilities. Provides an optimal environment for the development of coldchain logistics systems.
Korea's Largest Bio-Industry Cluster
Six major government agencies, including the MFDS and the Korea Disease Control and Prevention Agency, major biopharmaceutical companies, are located here.
1,500+ Bio-related Companies
Focus on various bio-healthcare companies, including vaccines, biopharmaceuticals, and medical devices.
Central Region Logistics hub
Adjacent to KTX Osong Station&Cheongju INT’L Airport, accessible from major domestic cities within an hour.
Advanced R&D Infrastructure
Specialized research and development facilities, including a state-of-the-art medical complex and a biosafety assessment center
Incheon IFEZ (Incheon Free Economic Zone)
As a HUB for the global logistics network. Incheon IFEZ serves Global connectivity through its international airport or ports and enables FIRSTLO's cold chain logistics to expand overseas.
Adjacent to Incheon INT’L Airport/Port
Connecting over 100 cities worldwide, it handles 70 million passengers and 3 million tons of cargo annually.
Global Logistics Connectivity
Northeast Asia's logistics hub, boasting the shortest sea and air routes to China and Japan.
Special Benefits of Free Economic Zones
Optimizing global business with tax benefits, deregulation, and a foreign-friendly environment
Dedicated Coldchain Logistics Infrastructure
Establishing temperature-controlled warehouses, specialized containers, and dedicated pharmaceutical logistics facilities.
Chungbuk-Incheon Consortium Synergy Effect
Regional Strengths
A Bio-Coldchain Hub Leveraging the Regional Characteristics of Chungbuk & Incheon.
Chungbuk Incheon
The Center of the Bio Industry in Central Korea A hub of global connectivity & INT’L logistics
Osong Bio Cluster
As the largest bio-industry cluster in Korea with a high concentration of production facilities for temperature-sensitive bio products such as pharmaceuticals and vaccines, we are building the best bio ecosystem in Korea where cutting-edge bio companies and research institutes collaborate.
Central Region Logistics Hub
A diverse logistics network via railways, highways, and airports provides nationwide accessibility. This maximizes speed and efficiency, crucial requirements for the cold chain, enabling rapid delivery to consumer markets nationwide
Large-Scale Logistics Infrastructure
The location is ideal for building a large-scale logistics center, and development of a specialized cold chain logistics complex is underway. A specialized refrigerated/frozen logistics system for bio products is being established..
1,500+
Number of Companies in Osong and Chungbuk Bio-Industry Clusters
Production Share
Ideal location for building a large-scale logistics center Development of a specialized coldchain logistics complex Building a specialized refrigerated/frozen logistics system
Incheon Free Economic Zone(IFEZ)
The IFEZ established in Songdo, Yeongjong, & Cheongna have attracted global bio companies. Various deregulation measures and incentives provide a favorable environment for attracting domestic and international bio companies.
Airport and Port Infrastructure
Boasting excellent global accessibility via Incheon Int’l Airport and Incheon Port, which is Asia's leading hub airport, boasts advanced cold chain facilities, making it ideal for the international transport of temperature-sensitive biopharmaceuticals.
Growth of the Bio Industry
Major domestic and international pharmaceutical & biotech companies are located in Songdo, where vaccine and biopharmaceutical production isactive.Theproductionanddistributionoftemperaturesensitivebiopharmaceuticalsisparticularlyconcentrated.
19.9%
Domestic Production Share of the Incheon Region's Bio Industry
Smart Logistics Network
Building a smart cold chain logistics center utilizing IoT, AI, and other technologies. Major domestic and international logistics companies operate logistics centers in Incheon. Serving as a hub for the global cold chain network.
Roadmap and Milestones
FIRSTLO Platform's Four-Year Development Plan and Key Milestones
2024
-Project development promotion
-Core technology R&D
-Initial platform construction
2025
-Thailand demonstration project underway
-Overseas market validation and feedback
-Platform development complete
-Platform functionality enhancements
2026
-Development, Verification, and Commercialization
-All core functions implemented
-Preparing for entry into new markets
-Full-scale entry into overseas markets
Key Milestones
Promotion of platform development (2024)
Promoting the development of core technologies for a blockchain-based bio AIoT coldchain logistics platform
Design initial implementation of a blockchain ledger AI prediction algorithms, and an integrated IoT sensor architecture
Completion of core technology planning and commencement of development
Development Completed (2025)
All core functions of the blockchain-based bio AIoT cold chain logistics platform have been developed. Overall system stabilization and performance optimization and infrastructure for large-scale operations have been established
Achieving 100% platform completion and system verification
2027
-Expanding the global network
Thailand
Demonstration Projec(2025)
Tracking Botox products. Conducting a verification project. Improving functionality through platform validation & performance evaluation in overseas markets Feedback generated.
Securing international partnerships and verifying overseas markets
Commercialization & global expansion (2026)
Simultaneously conducting development & verification, Commercialization, and are entering the global market in earnest.
Expanding services and providing localized solutions in key regions such as Asia, Europe, and North America. - 43 -
Expanding into three global continents and securing clients
Partners and Clients
Trusted Partnerships in the FIRSTLO Ecosystem
Building a Global Cold Chain Ecosystem
FIRSTLO is building a global cold chain ecosystem with leading partners in the technology, logistics, and bio industries. Each partner contributes to the platform's development based on their expertise.
Technology Partner
Blockchain and AI technology companies provide the core technologies of the FIRSTLO platform. They integrate cutting-edge technologies such as distributed ledger technology, machine learning algorithms, and IoT sensor networks to ensure stable services.
Logistics Partner
Global transportation companies and cold chain specialists, including logistics warehouses, provide real-time temperature-controlled transportation services.
Through international air, sea, and land transportation networks, we ensure a seamless cold chain.
Bio Customer Global Expanding
Major domestic and international pharmaceutical and biotech companies are safely transporting and tracking temperature-sensitive pharmaceuticals, such as vaccines, blood products, and cell/gene therapies, through the FIRSTLO platform.
Starting with Thailand, we have successfully entered the Southeast Asian market and provide specialized services for the international transportation of high-priced pharmaceuticals, such as Botox. We plan to expand into Europe, the Middle East, and the Americas in the future.
Experience the future of cold chain logistics with TABS Company.
If you'd like to learn more about our innovative solutions for bio-cold chain logistics, please contact us anytime. The TABS team will be happy to assist you.
Phone No. 82-43-904-2613
Address #202, 4-2, Dukkeobi-ro 94beon-gil (Sannam-dong) Seowon-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea
