M4 Drugs Affecting the Respiratory System - University Of Central Missouri - NUR 4013

Drugs Affecting the Respiratory System 

Overview o Bronchodilators o Leukotriene modifiers o Inhaled corticosteroids o Oxygen o Antihistamines o Decongestants o Mucolytics* o Cough preparations

 Beta2 Receptor Agonists o Short-acting beta agonists SABAs  Albuterol (ProAir, Ventolin, Proventil)  Selective beta2 agonist with minor beta1 activity  Levalbuterol is where the (S)-isomer from racemic albuterol is removed   Metaproterenol (Alupent)  Terbutaline (Brethine, Brethaire)  Bitolterol (Tornalate)  Pirbuterol (Maxair )  Levalbuterol (Xopenex) o Long-acting beta agonists LABAs  Salmeterol (Serevent)  Salmeterol more selective for beta2 receptors compared with albuterol and has minor beta1 activity  12-hour half-life  Formoterol (Foradil)  Indacaterol (Arcapta Neohaler)  Arformoterol (Brovana) o Ultra-long-acting beta2 receptor agonists (B2RAs)  Olodaterol (Striverdi Respimat)  Vilanterol

 Beta2 Agonists o precautions and contraindications