The South African Journal of Science is a multidisciplinary science journal published bimonthly by the Academy of Science of South Africa. Our mandate is to publish original research with an interdisciplinary or regional focus and to provide a forum for discussion of news and developments in research and higher education. About the cover: Alcohol is a major contributing factor to the burden of road traffic crashes and injuries in South Africa. Sukhai and colleagues review global research and experiences with the adoption of zero-tolerance approaches to drink-driving, along with key South African contextual considerations, to provide recommendations for advancing zero-tolerance drink-driving legislation in South Africa. Other articles in this issue include: Sorghum for food security | Gender gap in publication output | Zero-carbon building