International Journal of Mathematics and Physical Sciences Research ISSN 2348-5736 (Online) Vol. 10, Issue 2, pp: (27-32), Month: October 2022 - March 2023, Available at: www.researchpublish.com
Studies on Phytochemical investigation of Medicinal Plant Mesua Ferrea 1
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Mr. Naveen Chauhan , Dr. Arti Chaurasia 1
Research Scholar, Department of Chemistry, Nims Institute of Engineering & Technology NIMS University Rajasthan, Jaipur 2
Asst. Professor, Department of Chemistry, Nims Institute of Engineering & Technology NIMS University Rajasthan, Jaipur DOI: https://doi.org/10.5281/zenodo.7230268
Published Date: 20-October-2022
Abstract: The methanolic extracts of leaves and flowers of Mesua Ferrea have exhibited significant broad spectrum antimicrobial activity. Further work is being carried out to isolate and identify the active constituents of the plant responsible for antimicrobial activity. The purpose of our research was methanolic extract of the plant was qualitatively investigated for phytochemicals using standard procedures which revealed the presence of various important bioactive chemical entities. Keywords: bioactive, phytochemicals, Mesua Ferrea.
1. INTRODUCTION Traditional medicines for human diseases have been widely used in many parts of the world. Herbal plants are usually the primary source of medicine in many developing countries. Natural product compounds from plants provide biologically active compounds. Mesua ferrea Linn. belonging to the family Clusiaceae (Guttiferea) is known in Hindi as ‘Nagkeshar’ and in English as Ceylon Ironwood. It is a medium to large evergreen tree with short trunk, often buttressed at the base, found in the Himalayas from Nepal eastward, in north-eastern India it occurs in dry hilly forests of Rajasthan, Madhya Pradesh, Gujarat, Bihar, Assam, Orissa, Deccan Peninsula and the Andaman Islands, ascending to an altitude of 1.500m. The different parts of the plant contain glycosides, coumarins, flavanoids, xanthones, triglycerides and resins. Specifically, it contains α -copaene and germacrene D, ve β-amyrin, β-sitosterol, and a new cyclohexadione compound named as mesuaferrol (I), mesuanic acid (13), triterpenoids and resins, reducing sugars, and tannins, saponins, Mesuaferrone B, mesuol etc.
2. METHODS Phytochemical investigation of plant extract was carried out using standard procedure to identify carbohydrates, amino acids, alkaloids, steroids, glycosides, flavonoid etc. Plant materials The plant used in the study was collected from Pachmarhi district Hoshangabad Madhya Pradesh. It is authenticated by Dr. J. Anuradha (Department of Botany), NIET, NIMS University, Jaipur, Rajasthan. The collected plant materials were cleaned, shade dried, powdered coarsely in a blender and then stored in air-tight containers for further use. Preparation of extracts: A known weight (20 g) of the powdered plant part was extracted with 70% methanol for 30 hours in a Soxhlet apparatus. The obtained extracts were then filtered to remove residual parts of the precipitate. It was then evaporated at room temperature to get a crude dried extract. The dried extracts were weighed to determine the yield. It was stored in a deep freezer at - 20°C to preventthe loss of biological activity until used.
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