Principles of Drug Action Exam Bank
Course Introduction
Principles of Drug Action explores the fundamental mechanisms by which drugs interact with biological systems to produce therapeutic and adverse effects. The course covers key concepts including pharmacodynamics, pharmacokinetics, receptor theory, dose-response relationships, drug metabolism, and the factors influencing drug absorption, distribution, metabolism, and excretion. Students will gain insight into how drugs are designed, how their efficacy and safety are evaluated, and how individual variability including genetic, physiological, and pathological factors affects drug response. The course lays a foundation for understanding clinical applications of pharmacology in health care and research settings.
Recommended Textbook
Introduction to Clinical Pharmacology 7th Edition by Marilyn Edmunds
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24 Chapters
575 Verified Questions
575 Flashcards
Source URL: https://quizplus.com/study-set/1131 Page 2
Chapter 1: Pharmacology and the Nursing Process in LPN Practice
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25 Verified Questions
25 Flashcards
Source URL: https://quizplus.com/quiz/22201
Sample Questions
Q1) When performing an initial patient assessment,which of the following would be considered objective data? (Select all that apply. )
A) Abdominal pain reported by the patient
B) The patient's vital signs (blood pressure,pulse,temperature,etc. )
C) Documents such as old laboratory results,EEG printouts,or x-rays brought in by the patient
D) Home medications with patient labels brought in by the patient
E) The chief problem or complaint as stated by the patient
Answer: B,C,D
Q2) An LVN/LPN works on a very busy 35-bed medical-surgical unit.The RN team leader gives you a syringe with "pain medication" in it and asks the LPN/LVN nurse to administer this medication to a patient.The nurse's first action is which of the following?
A) Assist the team leader by giving the medication as requested for this time only.
B) Administer the medication this time because it is an emergency.
C) Take time and prepare the medication yourself and give as prescribed.
D) You don't have to do anything;it is not your patient.
Answer: C
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Chapter 2: Patient Teaching and Health Literacy
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31 Verified Questions
31 Flashcards
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Sample Questions
Q1) Patients may have difficulty in meeting treatment goals for which of the following reasons? (Select all that apply. )
A) Lack of understanding of the goals
B) Incongruity between patient and nursing goals
C) Compliance with all aspects of the treatment plan
D) Limited financial resources
Answer: A,B,D
Q2) A patient begins medication therapy for hypertension.Which of the following reasons is most likely to make the scheduled teaching plan change for this patient?
A) The patient's outlook for his condition changes.
B) The patient writes down some of the information.
C) The patient has no questions after being taught.
D) The patient's systolic blood pressure falls below 60 mm Hg with therapy. Answer: D
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Chapter 3: Legal Aspects Affecting the Administration of Medications
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24 Verified Questions
24 Flashcards
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Sample Questions
Q1) At change of shift,two nurses (one from each shift)discover a discrepancy in the narcotics inventory for morphine 5 mg/mL vials.The count is short by one vial.Which of the following steps should be taken to reconcile the count? (Select all that apply. )
A) All nurses having access to the Pyxis machine or the narcotics cabinet should be asked about medication they have given.
B) Steps must be retraced to identify whether someone forgot to record any medication removed.
C) Check patient charts (MAR)to see if medication was given that was not signed for on the inventory report.
D) Notify the nursing supervisor (charge nurse)and the pharmacy department of any undocumented (unreconciled)discrepancy.
E) None of above
Answer: A,B,C,D
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5
Chapter 4: Foundations and Principles of Pharmacology
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26 Verified Questions
26 Flashcards
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Sample Questions
Q1) Propranolol (Inderal)is eliminated almost entirely via metabolism by the liver after oral administration.This necessitates giving much larger doses by mouth as compared to intravenous (IV)administration.For this reason,propranolol is a good example of a drug that exhibits which of the following effects?
A) Hepatotoxic
B) Nephrotoxic
C) First-pass
D) Displacement
Q2) The patient tells the nurse that he gets a headache after taking an antihypertensive medication.The nurse explains that this is which of the following?
A) Uncommon symptom
B) Side effect
C) Drug interaction
D) Desired effect
Q3) Which of the following is always true regarding the generic name for a drug?
A) It is capitalized when written.
B) It is the same in any country.
C) It is assigned by a specific manufacturer.
D) It is similar to the chemical name.
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Page 6
Chapter 5: Lifespan and Cultural Modifications
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18 Verified Questions
18 Flashcards
Source URL: https://quizplus.com/quiz/22205
Sample Questions
Q1) Which of the following people,as a condition of their work,are required to maintain current immunizations? (Select all that apply. )
A) People in the military
B) Chefs
C) Health care providers
D) Teachers
Q2) Because of their compromised immunity,patients with AIDS are at greater risk for serious complications due to fungal infections.Treatment of such a condition is aimed at killing which of the following infections and in how many days? (Select all that apply. )
A) Candida albicans
B) 7 days
C) Herpes simplex
D) 2 days
Q3) Which of the following people would be at the highest risk for drug noncompliance?
A) A 2-year-old in a day care center
B) A 10-year-old receiving antibiotics for an ear infection
C) A 65-year-old on a fixed income taking five different medications
D) A 95-year-old in a long-term care facility
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7
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19 Verified Questions
19 Flashcards
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Sample Questions
Q1) The Dietary Supplement Health and Education Act passed by Congress in 1994 addresses which of the following issues with OTC dietary supplements? (Select all that apply. )
A) Disease claims
B) Functional cure
C) Preventions
D) Toxicities
Q2) Iron supplements are used in the treatment of which of the following conditions?
A) Anemia
B) Osteoporosis
C) Esophageal reflux
D) Constipation
Q3) Effects of calcium on the body include which of the following? (Select all that apply. )
A) Large doses of calcium will not harm the body when taken on a full stomach.
B) Calcium can limit the absorption of iron and other trace elements.
C) Calcium can cause constipation and reduce kidney function.
D) Calcium may prevent bone loss in older men.
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Page 8
Chapter 7: Review of Mathematical Principles
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19 Verified Questions
19 Flashcards
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Sample Questions
Q1) Which of the following is the solution to the problem? 1/16 + 1/2 + 3/8 = ___.
A) 5/26
B) 15/16
C) 5/16
D) 17/16
Q2) Which of the following represents 4/8 raised to a higher term?
A) 8/16
B) 4/16
C) 1/16
D) 2/16
Q3) Which of the following is a common denominator with 28?
A) 14
B) 12
C) 11
D) 13
Q4) The Roman numeral XLII should be interpreted as which of the following numbers?
A) 492
B) 92
C) 62
D) 42
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Chapter 8: Mathematical Calculations Used in Pharmacology
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15 Verified Questions
15 Flashcards
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Sample Questions
Q1) Which of the following is equal to 2 tablespoonfuls?
A) 30 mL
B) 15 mL
C) 10 mL
D) 5 mL
Q2) Which of the following is equal to 1500 mcg?
A) 0.15 mg
B) 15 mg
C) 1.5 mg
D) 1,500,000 mg
Q3) A patient's weight is 68 kg.Which of the following represents the patient's weight in pounds?
A) 150 lb
B) 148 lb
C) 135 lb
D) 138 lb
Q4) Calculate the following: 1 kg = _____g.
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Chapter 9: Calculating Drug Dosages
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17 Verified Questions
17 Flashcards
Source URL: https://quizplus.com/quiz/22209
Sample Questions
Q1) Parenteral medications come in different forms.Which of the following are considered parenteral medications? (Select all that apply. )
A) Prefilled syringe
B) Single-dose ampule
C) Multidose vial
D) Bottle volume pack
Q2) Place the following steps in the correct order for performing a dosage calculation.
A)Calculate the dosage.
B)Change the dosages to the same unit of measurement.
C)Use common sense.
D)Reduce to the simplest terms.
Q3) Valium 2.5 mg is ordered PO three times daily.The medication comes in 5-mg tablets.Which of the following represents the portion of the 5-mg tablet that the nurse will administer to the patient?
A) 1/4 tablet
B) 1/3 tablet
C) 1/2 tablet
D) 3/4 tablet
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Chapter 10: Preparing and Administering Medications
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20 Verified Questions
20 Flashcards
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Sample Questions
Q1) Which of the following represents the proper way for a nurse to administer an oral capsule?
A) Tell the patient to swallow it whole.
B) Pierce it with a needle and squeeze into the mouth.
C) Crush and dilute it in warm water.
D) Tell the patient to chew it completely.
Q2) When a patient is experiencing a life-threatening emergency,the nurse may be given an order to administer medication via which of the following routes?
A) IV
B) IM
C) Subcutaneous
D) Rectal
Q3) Injectable iron should be administered by which of the following injection methods?
A) Subcutaneous
B) Intradermal
C) Z-track intramuscular injection
D) IV piggyback
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Chapter 11: Allergy and Respiratory Medications
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20 Verified Questions
20 Flashcards
Source URL: https://quizplus.com/quiz/22211
Sample Questions
Q1) A patient is recovering from bronchitis.He is producing large amounts of thick mucus,especially in the mornings.The physician might do which of the following?
A) Suggest he drink a glass of water with each meal.
B) Suggest he drink two glasses of orange juice daily.
C) Order an expectorant and tell the patient to force fluids.
D) Order an antitussive.
Q2) A 17-year-old high school wrestler comes in for his regularly scheduled appointment for asthma.He reports no acute problems now with wheezing,coughing,shortness of breath,or tightness in his chest.He might be a candidate for prophylactic treatment with which of the following medications?
A) Theochron
B) Sus-Phrine
C) Cromolyn sodium
D) Proventil
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Chapter 12: Antiinfective Medications
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27 Verified Questions
27 Flashcards
Source URL: https://quizplus.com/quiz/22212
Sample Questions
Q1) A medication that interferes with an important life process of a bacterial organism,making it weaker or incapable of reproducing,is considered to be which of the following?
A) Pathogenic
B) Bacteriostatic
C) Bactericidal
D) Microbial
Q2) Which of the following patients are at highest risk for developing tuberculosis?
A) All children up to the age of 7 years
B) Individuals whose skin tests have become positive in the last 2 years
C) All children exposed to sunlight between noon and 6:30 PM
D) Individuals with debilitating diseases such as asthma,hypertension,and ulcers
Q3) The nurse is teaching a patient about possible side effects when taking minocycline,a broad-spectrum antibiotic.Which of the following is the most common side effect with this drug?
A) Salty taste in the mouth
B) Feeling of vertigo
C) Edema in the feet and legs
D) Ringing in the ears
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Page 14
Chapter
Medications
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20 Verified Questions
20 Flashcards
Source URL: https://quizplus.com/quiz/22213
Sample Questions
Q1) A patient comes into the clinic complaining of being exposed to a coworker who has the flu.The patient is asymptomatic.The nurse anticipates that the physician will order which of the following?
A) Flumadine (rimantadine)
B) Valtrex (valacyclovir)
C) Ziagen (abacavir)
D) Crixivan (indinavir)
Q2) Which of the following conditions can result when antifungals are taken concurrently with corticosteroid therapy?
A) CNS depression
B) Superinfection
C) Anemia
D) Photophobia
Q3) "Crix belly" is a syndrome characterized by which of the following? (Select all that apply. )
A) Elevated CBCs
B) Elevated triglycerides
C) Elevated cholesterol
D) Fat accumulation
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Chapter 14: Antineoplastic Medications
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20 Verified Questions
20 Flashcards
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Sample Questions
Q1) For which of the following reasons must a patient keep his or her chemotherapy medications in a locked cabinet?
A) These medications are very costly.
B) These medications are very toxic.
C) These medications have narcotic effects.
D) These medications are hard to replace monthly.
Q2) A patient in treatment for multiple myeloma is on Mesnex (ifosfamide).She reports to the nurse that she is having bouts of nausea and has been unable to eat.Which of the following would be the best advice to give her?
A) Take nothing by mouth until this passes.
B) Replace fluid losses right away.
C) Only eat nonsalty foods.
D) Hold ice chips in your mouth.
Q3) Common adverse reactions associated with antineoplastic drugs include which of the following?
A) Alopecia and bone marrow depression
B) Bone marrow stimulation and nausea
C) Diarrhea and blurred vision
D) Anorexia and rhinorrhea
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Page 16
Chapter 15: Cardiovascular and Renal Medications
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38 Verified Questions
38 Flashcards
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Sample Questions
Q1) A patient is scheduled to leave the hospital tomorrow.He has been instructed to take nitroglycerin sublingually if angina is experienced.Which of the following instructions would the nurse give concerning the use of this medication?
A) "During an acute attack of angina,you may repeat the dose after 5 to 10 minutes one time.If the pain is not relieved,go to the physician's office."
B) "You should never repeat a dose,but you should notify the physician if the pain is not relieved."
C) "If the pain is not relieved within 3 minutes,you should repeat the dose every 3 minutes times two more doses.If there is still no relief,you should go immediately to an emergency department."
D) "You can take as many tablets as necessary until the pain is relieved,then report it to the physician."
Q2) Lidocaine may be used for treating dysrhythmias in which of the following situations?
A) The dysrhythmias are not ventricular in nature.
B) The label indicates that the medication contains preservatives.
C) The medication is given intravenously.
D) The patient is alert and responsive.
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17
Chapter 16: Central and Peripheral Nervous System
Medications
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24 Verified Questions
24 Flashcards
Source URL: https://quizplus.com/quiz/22216
Sample Questions
Q1) Which of the following statements is true regarding benzodiazepines?
A) These drugs are safe to use in pregnancy.
B) These drugs may be habit forming.
C) If a dose is forgotten,double the next dose.
D) Caffeine enhances the effect.
Q2) Long-acting barbiturates are used in the treatment of status epilepticus as well as seizures caused by which of the following? (Select all that apply. )
A) Fever
B) Tetanus
C) Drugs
D) Arthritis
Q3) Which of the following medications is classified as a benzodiazepine?
A) Lorazepam (Ativan)
B) Buspirone (BuSpar)
C) Benztropine (Cogentin)
D) Chlorpromazine (Thorazine)
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18
Chapter 17: Medications for Pain Management and Anesthesia
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18 Verified Questions
18 Flashcards
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Sample Questions
Q1) Patients receiving a narcotic agonist analgesic should be watched for which of the following signs or symptoms?
A) Severe hypertension
B) Reduced cough reflex
C) Overeating
D) Restlessness
Q2) Contraindications to taking nonnarcotic analgesics include which of the following conditions? (Select all that apply. )
A) Hypertension
B) Emotional problems
C) Drug abuse
D) Asthma
Q3) After a patient has been on a narcotic agonist drug for a week,the nurse would next expect the physician to do which of the following?
A) Take the patient off all pain medications.
B) Continue the patient on the medication for another week.
C) Have the patient use distractions from pain.
D) Give another method for pain relief.
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Chapter 18: Anti-inflammatory, Musculoskeletal, and Anti-arthritis Medications
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27 Verified Questions
27 Flashcards
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Sample Questions
Q1) Which of the following is the most common complication when taking NSAIDs?
A) GI upset
B) Constipation
C) Fluid overload
D) Headaches
Q2) Methotrexate is used in the treatment of which of the following conditions?
A) Severe back pain
B) Chronic gout pain
C) Osteoarthritis
D) Rheumatoid arthritis
Q3) Older adult patients on NSAIDs should be monitored for which of the following?
A) Incidence of peptic ulcers
B) Decreased urine
C) Blood in urine
D) Night fevers
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Page 20
Chapter 19: Gastrointestinal Medications
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20 Verified Questions
20 Flashcards
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Sample Questions
Q1) A patient with gastritis asks why the physician put her on an antacid when she has already been eating well.Which of the following would be the best response? (Select all that apply. )
A) "Antacids are used to neutralize the acidity in your stomach between meals."
B) "Although food helps to reduce discomfort by buffering your stomach acid,the antacids will help to neutralize the acid and reduce your pain."
C) "All medications should be taken with an antacid."
D) "Antacids are also used to treat constipation."
Q2) One of the nurse's older adult patients is abusing laxatives.Which of the following would be an appropriate intervention for this patient to help reduce this chronic laxative use and dependency?
A) Advise the patient to take a laxative once weekly.
B) Stop the patient from taking any laxatives.
C) Have the patient take an enema instead of a laxative.
D) Have the patient drink 6 to 8 glasses of water each day.
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21
Chapter 20: Hematologic Products
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26 Verified Questions
26 Flashcards
Source URL: https://quizplus.com/quiz/22220
Sample Questions
Q1) Which of the following tests will the nurse evaluate after the physician makes an adjustment in a patient's heparin dose in order to determine the effect of the change?
A) aPTT
B) PT
C) INR
D) DIC panel
Q2) In checking the chart of an elderly female outpatient on anticoagulant therapy,the LPN/LVN notes that the patient's lab values are off.The patient says she takes her medication as prescribed,so the nurse asks about her dietary intake.Which of the following foods might have an effect on anticoagulant therapy?
A) Broccoli
B) Eggplant
C) Oranges
D) Grapes
Q3) Anticoagulant therapy is used to do which of the following?
A) Thin the blood
B) Lyse existing clots
C) Increase viscosity of the blood
D) Prevent new clot formation
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Chapter 21: Hormones and Steroids
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28 Verified Questions
28 Flashcards
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Sample Questions
Q1) Hormones used in the suppression of ovulation include which of the following?
A) Estrogens and progestins
B) Luteinizing hormone and follicle-stimulating hormone
C) Androgens and progestins
D) Endorphins and androgens
Q2) A newly diagnosed type 2 diabetic patient is started on a new drug that comes from incretin hormones.Glucagon-like peptide 1 (GLP1)is used because of which of the following effects?
A) It has the least allergic effect.
B) It is easy to administer.
C) It inhibits glucagon secretion.
D) It slows islet growth.
Q3) When using drugs for labor induction,the intensity of uterine contractions should not be more than which of the following?
A) 50 mm Hg
B) 20 mm Hg
C) 80 mm Hg
D) 10 mm Hg
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Chapter 22: Immunologic Medications
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27 Verified Questions
27 Flashcards
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Sample Questions
Q1) Which of the following biologic agents are used in a routine schedule for active immunizations?
A) PPD
B) Toxoids
C) Antigens
D) Toxins
Q2) Which of the following is an appropriate intervention to relieve local discomfort from an immunization?
A) Application of emollients
B) Application of ice
C) Application of lidocaine ointment
D) Acetaminophen
Q3) There is an increased risk in using immunologic agents in people with compromised immune status.Which of the following people is most at risk for a compromised immune status?
A) A postal worker
B) A college student
C) A neonate
D) A pilot
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Page 24
Chapter 23: Topical Medications
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27 Flashcards
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Sample Questions
Q1) The nurse explains to the patient the procedure she will use to apply a wet dressing to his open wound.The nurse will use which of the following solutions?
A) Salicylic acid
B) Colloidal bath
C) Burow solution
D) Urea
Q2) Trifluridine is an antiviral agent that is used in the eyes to treat which of the following conditions?
A) Dry eye
B) Corneal ulcers
C) Conjunctivitis
D) Inflammation
Q3) Burow solution is used in wet soaks for inflammation of the skin.Which of the following patient teaching points would the nurse include? (Select all that apply. )
A) Use a single layer of dressings.
B) Moisten multiple layers of dressings.
C) Reapply every 15 to 30 minutes for 4 to 8 hours.
D) These dressings will promote circulation and provide warmth.
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Chapter 24: Vitamins and Minerals
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39 Flashcards
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Sample Questions
Q1) The highest amount of vitamin E is found in which of the following food sources?
A) Meat
B) Milk and cheese
C) Wheat germ
D) Fish
Q2) Vitamin A is used to do which of the following?
A) Treat blood deficiency when doing a blood transfusion
B) Stop bleeding
C) Make stool softer
D) Treat eye diseases and night blindness
Q3) Which of the following vitamins is important in red blood cell formation?
A) K
B) D
C) Folic acid
D) B
Q4) Magnesium is found in which of the following foods?
A) Bread
B) Meat
C) Eggs
D) Legumes
Page 26
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