Pathology Review for USMLE Exam Bank
Course Introduction
This course offers a comprehensive review of pathology concepts essential for success on the USMLE examinations. Focusing on high-yield topics, it covers the etiology, pathogenesis, morphological changes, and clinical significance of major diseases, integrating both foundational principles and clinical correlations. Students will reinforce their understanding through case-based discussions, illustrative images, and systematic overviews of organ system pathology, preparing them to confidently answer pathology questions and apply this knowledge in clinical settings.
Recommended Textbook
Pathology Secrets 3rd Edition by Ivan Damjanov MD PhD
Available Study Resources on Quizplus
23 Chapters
386 Verified Questions
386 Flashcards
Source URL: https://quizplus.com/study-set/1036
Page 2
Chapter 1: Cell Pathology
Available Study Resources on Quizplus for this Chatper
10 Verified Questions
10 Flashcards
Source URL: https://quizplus.com/quiz/20520
Sample Questions
Q1) Which of the following organs undergoes atrophy during childhood and adolescence?
A) Uterus
B) Breasts
C) Thymus
D) Thyroid
E) Adrenals
Answer: C
Q2) Which of the following is an oxygen radical?
A) Hydrogen peroxide
B) Acid hydrolase
C) ATP
D) Carbon tetrachloride
E) Lipofuscin
Answer: A
To view all questions and flashcards with answers, click on the resource link above. Page 3
Chapter 2: Inflammation
Available Study Resources on Quizplus for this Chatper
10 Verified Questions
10 Flashcards
Source URL: https://quizplus.com/quiz/20521
Sample Questions
Q1) Aspirin can inhibit some aspects of inflammation by inhibiting the synthesis of:
A) Histamine
B) Prostaglandin and thromboxane
C) Serotonin
D) Hageman factor
E) Arachidonic acid
Answer: B
Q2) A bacterial throat infection ("strep throat")is associated with a white exudate surrounded by reddened mucosa.This is an example of:
A) Serous inflammation
B) Fibrinous inflammation
C) Abscess
D) Gangrene
E) Ulcerative inflammation
Answer: B
To view all questions and flashcards with answers, click on the resource link above.
4
Chapter 3: Immunopathology
Available Study Resources on Quizplus for this Chatper
13 Verified Questions
13 Flashcards
Source URL: https://quizplus.com/quiz/20522
Sample Questions
Q1) Which of the following diseases is mediated by immunoglobulin E (IgE)attached to mast cells?
A) Hay fever (allergic rhinitis)
B) Systemic lupus erythematosus
C) Sarcoidosis
D) Polyarteritis nodosa
E) Ankylosing spondylitis
Answer: A
Q2) Autoimmune disease presenting with hyperthyroidism is called:
A) Goodpasture's syndrome
B) Sarcoidosis
C) DiGeorge's disease
D) Graves' disease
E) Myasthenia gravis
Answer: D
To view all questions and flashcards with answers, click on the resource link above.
5
Chapter 4: Neoplasia
Available Study Resources on Quizplus for this Chatper
14 Verified Questions
14 Flashcards
Source URL: https://quizplus.com/quiz/20523
Sample Questions
Q1) Hodgkin's lymphoma is a neoplasm that typically involves the:
A) Brain
B) Lungs
C) Heart
D) Liver
E) Lymph nodes
Q2) Alpha-fetoprotein is a tumor marker for malignant tumors originating in the:
A) Brain
B) Lung
C) Liver
D) Uterus
E) Thyroid
Q3) The incidence of which cancer has been rising in the United States during the past 20 years?
A) Carcinoma of the lung
B) Carcinoma of the liver
C) Carcinoma of the stomach
D) Carcinoma of the thyroid
E) Malignant brain tumors
To view all questions and flashcards with answers, click on the resource link above.
Page 6
Chapter 5: Genetic and Developmental Diseases
Available Study Resources on Quizplus for this Chatper
13 Verified Questions
13 Flashcards
Source URL: https://quizplus.com/quiz/20524
Sample Questions
Q1) All the following are considered possible causes of the TORCH syndrome except:
A) Toxoplasma
B) Rubella virus
C) Cytomegalovirus
D) Herpesvirus
E) Alcohol
Q2) Sudden infant death syndrome typically occurs:
A) At the time of birth
B) During the first few hours after birth
C) During the first week after birth
D) During the first month of life
E) Any time between 2 and 9 months of the first year of life
Q3) Dilatation of lateral ventricles of the brain found in TORCH syndrome is called:
A) Microphthalmia
B) Chorioretinitis
C) Hydrocephalus
D) Cataract
E) Vesicles
To view all questions and flashcards with answers, click on the resource link above.
7
Chapter 6: Fluid and Hemodynamic Disorders
Available Study Resources on Quizplus for this Chatper
24 Verified Questions
24 Flashcards
Source URL: https://quizplus.com/quiz/20525
Sample Questions
Q1) So-called heart failure cells found in sputum are caused by:
A) Right ventricular failure
B) Left ventricular failure
C) Cardiac hemorrhage
D) Aortic hemorrhage
E) Cyanosis
Q2) Ingrowth of granulation tissue into a venous thrombus is called:
A) Conglutination
B) Sedimentation
C) Margination
D) Organization
E) Infarction
Q3) Which of the following is a feature of an exudate but is not typical of a transudate?
A) Accumulation of fluid in a body cavity
B) Accumulation of fluid in the alveoli of the lung
C) Accumulation of fluid in the tissue,with subsequent swelling of the tissue ("tumor")
D) Accumulation of protein in extracellular spaces
E) Accumulation of numerous polymorphonuclear leukocytes in extracellular spaces
To view all questions and flashcards with answers, click on the resource link above.
8
Chapter 7: The Cardiovascular System
Available Study Resources on Quizplus for this Chatper
14 Verified Questions
14 Flashcards
Source URL: https://quizplus.com/quiz/20526
Sample Questions
Q1) The most common form of arterial hypertension is considered to be:
A) Essential or idiopathic
B) Caused by kidney disease
C) Caused by adrenal cortical hyperactivity
D) Secondary to adrenal medullar tumors
E) Secondary to the narrowing of the aorta
Q2) Atherosclerotic aneurysms are most often located in the:
A) Coronary arteries
B) Ascending aorta
C) Thoracic aorta
D) Abdominal aorta
E) Iliac arteries
Q3) All the following represent iatrogenic heart lesions except:
A) Alcoholic cardiomyopathy
B) Radiation-induced heart disease
C) Doxorubicin-induced heart disease
D) Digitalis toxicity
E) Postcardiotomy pericarditis
To view all questions and flashcards with answers, click on the resource link above.
9
Chapter 8: The Respiratory System
Available Study Resources on Quizplus for this Chatper
15 Verified Questions
15 Flashcards
Source URL: https://quizplus.com/quiz/20527
Sample Questions
Q1) The major pulmonary complication of congenital alpha -antitrypsin deficiency is:
A) Chronic bronchitis
B) Bronchiectasis
C) Atelectasis
D) Emphysema
E) Mesothelioma
Q2) Pleural tumors are usually associated with:
A) Pneumothorax
B) Hemothorax
C) Pyothorax
D) Pleural effusion
E) Empyema
Q3) The most important cause of emphysema is:
A) Cigarette smoking
B) Air pollution in the cities
C) Tuberculosis
D) AIDS
E) Asthma
To view all questions and flashcards with answers, click on the resource link above. Page 10
Chapter 9: The Hematopoietic and Lymphoid Systems
Available Study Resources on Quizplus for this Chatper
19 Verified Questions
19 Flashcards
Source URL: https://quizplus.com/quiz/20528
Sample Questions
Q1) Sickle cell hemoglobin is routinely identified in the laboratory by:
A) Polarized light microscopy
B) Electron microscopy
C) Electrophoresis
D) Immunochemistry
E) Electron spin microscopy
Q2) Overall,the most common form of leukemia is:
A) Acute lymphoblastic leukemia
B) Acute myelogenous leukemia
C) Chronic lymphocytic leukemia
D) Chronic myelogenous leukemia
E) Plasma cell leukemia
Q3) Epstein-Barr virus,a possible cause of Burkitt's lymphoma,has a predilection for infecting:
A) T-suppressor/cytotoxic lymphocytes
B) T-helper lymphocytes
C) Plasma cells
D) B lymphocytes
E) Eosinophils
To view all questions and flashcards with answers, click on the resource link above. Page 11
Chapter 10: The Gastrointestinal System
Available Study Resources on Quizplus for this Chatper
18 Verified Questions
18 Flashcards
Source URL: https://quizplus.com/quiz/20529
Sample Questions
Q1) Genetic predisposition to colonic cancer is inherited as an autosomal dominant trait in:
A) Hirschsprung's disease
B) Familial adenomatous polyposis syndrome
C) Peutz-Jeghers syndrome
D) Colonic diverticulosis
E) Ulcerative colitis
Q2) Obstructive ileus may be caused by all the following except:
A) Gallstones
B) Fecaliths
C) Volvulus
D) Incarceration of intestinal loops in a hernia sac
E) Spinal cord injury
Q3) Dental caries begins by the formation of:
A) Pockets of periodontal inflammation
B) Bacterial plaques on the surface of the tooth
C) Periapical granuloma
D) Periapical abscess
E) Radicular cyst
To view all questions and flashcards with answers, click on the resource link above.
Page 12
Chapter 11: The Liver and Biliary System
Available Study Resources on Quizplus for this Chatper
24 Verified Questions
24 Flashcards
Source URL: https://quizplus.com/quiz/20530
Sample Questions
Q1) Gallbladder carcinoma is:
A) More common in females than in males
B) More often squamous than adenocarcinoma
C) More often invading the intestine than the liver
D) More common in young people than in old people
E) More often accompanied by jaundice than carcinoma of the common bile duct
Q2) Primary sclerosing cholangitis affects primarily:
A) Intercellular bile ductules along the liver cell plates
B) Small intrahepatic bile ductules
C) Small intrahepatic bile ducts
D) Extrahepatic bile ducts
E) Gallbladder
Q3) The most common malignant tumor of the liver is:
A) Hepatocellular carcinoma
B) Cholangiocellular carcinoma
C) Kupffer cell sarcoma
D) Carcinoid
E) Metastatic tumor from another site
To view all questions and flashcards with answers, click on the resource link above. Page 13
Chapter 12: The Pancreas
Available Study Resources on Quizplus for this Chatper
22 Verified Questions
22 Flashcards
Source URL: https://quizplus.com/quiz/20531
Sample Questions
Q1) Which of the following is an early sign of carcinoma of the head of pancreas?
A) Hiccups
B) Gastric regurgitation
C) Jaundice
D) Pain in the left upper abdominal quadrant
E) Ascites
Q2) Acute pancreatitis can be induced experimentally by all the following except:
A) Cholecystectomy
B) Obstruction of the main pancreatic duct
C) Mechanical disruption of the pancreatic acinar cells
D) Drugs that injure pancreatic acinar cells
E) Injection of bile into the main pancreatic duct
Q3) Fat necrosis typically found in and around the pancreas in acute pancreatitis is caused by a release of:
A) Amylase
B) Lipase
C) Peptidase
D) Pepsin
E) Cholecystokinin
To view all questions and flashcards with answers, click on the resource link above.
Page 14
Chapter 13: The Urinary Tract
Available Study Resources on Quizplus for this Chatper
11 Verified Questions
11 Flashcards
Source URL: https://quizplus.com/quiz/20532
Sample Questions
Q1) The most common malignant tumor of the urinary tract is:
A) Renal cell carcinoma
B) Wilms' tumor
C) Carcinoma of the renal pelvis
D) Carcinoma of the ureter
E) Carcinoma of the urinary bladder
Q2) The most common urinary stones are composed of:
A) Calcium phosphate
B) Magnesium ammonium sulfate
C) Uric acid
D) Cystine
E) Xanthine
Q3) A solid renal tumor of a 4-year-old child was histologically composed of immature cells reminiscent of fetal tubules.This tumor represents a(n):
A) Renal cell adenoma
B) Renal cell carcinoma
C) Wilms' tumor
D) Interstitial cell fibroma
E) Teratoma
To view all questions and flashcards with answers, click on the resource link above.
Page 15
Chapter 14: The Male Reproductive System
Available Study Resources on Quizplus for this Chatper
14 Verified Questions
14 Flashcards
Source URL: https://quizplus.com/quiz/20533
Sample Questions
Q1) Which of the following testicular tumors may cause premature puberty?
A) Seminoma
B) Yolk sac carcinoma
C) Teratoma
D) Leydig cell tumor
E) Sertoli cell tumor
Q2) Elevation of serum alkaline phosphatase in a patient with an enlarged prostate indicates that this man has:
A) Prostatitis
B) Benign prostatic hyperplasia
C) Carcinoma in situ of the prostate
D) Invasive carcinoma of the prostate that has spread to the urinary bladder
E) Carcinoma of the prostate that has metastasized to the bone
Q3) Most of the testicular tumors originate from:
A) Germ cells
B) Sertoli cells
C) Leydig cells
D) Stromal fibroblasts
E) Tunica vaginalis testis
To view all questions and flashcards with answers, click on the resource link above.
Page 16
Chapter 15: The Female Reproductive System
Available Study Resources on Quizplus for this Chatper
24 Verified Questions
24 Flashcards
Source URL: https://quizplus.com/quiz/20534
Sample Questions
Q1) Condyloma acuminatum is caused by:
A) Herpes simplex virus type 1
B) Herpes simplex virus type 2
C) Human papillomavirus
D) Chlamydia trachomatis
E) Treponema pallidum
Q2) A cystic ovarian lesion filled with clear,straw-colored fluid,showing multiple peritoneal metastases,is most likely a:
A) Mucinous cystadenoma
B) Mucinous cystadenocarcinoma
C) Serous cystadenoma
D) Serous cystadenocarcinoma
E) Sertoli-Leydig cell tumor
Q3) Most spontaneous abortions are consequences of:
A) Developmental anomalies of the fetus and/or placenta
B) Internal infections
C) Autoimmune disorders
D) Lack of estrogen in the maternal organism
E) Excess of progesterone during early pregnancy
To view all questions and flashcards with answers, click on the resource link above.
Page 17
Chapter 16: The Breast
Available Study Resources on Quizplus for this Chatper
10 Verified Questions
10 Flashcards
Source URL: https://quizplus.com/quiz/20535
Sample Questions
Q1) Approximately 75% of all the lymph draining from the breast flows into the:
A) Axillary lymph nodes
B) Internal mammary lymph nodes
C) External mammary lymph nodes
D) Substernal lymph nodes
E) Cervical lymph nodes
Q2) Acute mastitis is most often caused by:
A) Staphylococcus
B)E. coli
C) Mycobacterium tuberculosis
D) Herpes virus
E) Toxoplasma gondii
Q3) In contrast to nonfunctioning breasts,the breast of late pregnancy and postpartum period contains:
A) Periareolar ducts
B) Hyperplastic subareolar ducts
C) More connective tissue stroma
D) More epithelial buds
E) Acini
To view all questions and flashcards with answers, click on the resource link above. Page 18
Chapter 17: The Endocrine System
Available Study Resources on Quizplus for this Chatper
29 Verified Questions
29 Flashcards
Source URL: https://quizplus.com/quiz/20536
Sample Questions
Q1) Adrenal hypofunction (Addison's disease)may be caused by all except:
A) Adrenal tuberculosis
B) Bilateral primary adrenal carcinoma
C) Metastases of breast carcinoma to the adrenals
D) Autoimmune adrenalitis
E) Adrenal cortical hyperplasia
Q2) Neuroblastomas have peak incidence in which age group?
A) 1-5 years
B) 10-15 years
C) 20-25 years
D) 40-45 years
E) 60-65 years
Q3) The most common cause of Cushing's syndrome encountered in medical practice today is:
A) Adenoma of the pituitary
B) Adenoma of adrenal cortex
C) Adenoma of adrenal medulla
D) Carcinoma of adrenal cortex
E) Exogenous steroids administered by physicians
To view all questions and flashcards with answers, click on the resource link above.
Page 19
Chapter 18: The Skin
Available Study Resources on Quizplus for this Chatper
13 Verified Questions
13 Flashcards
Source URL: https://quizplus.com/quiz/20537
Sample Questions
Q1) Diabetes predisposes the skin to:
A) Tumors
B) Autoimmune diseases
C) Infections
D) Hyperplasia
E) Hyperpigmentation
Q2) Ringworm lesions are caused by:
A) Worms
B) Parasites
C) Fungi
D) Bacteria
E) Viruses
Q3) Prolonged suntanning causes:
A) Ulcers
B) Accelerated aging of the skin
C) Furuncles
D) Carbuncles
E) Psoriasis
To view all questions and flashcards with answers, click on the resource link above.
Page 20
Chapter 19: Bones and Joints
Available Study Resources on Quizplus for this Chatper
25 Verified Questions
25 Flashcards
Source URL: https://quizplus.com/quiz/20538
Sample Questions
Q1) Aseptic necrosis of bones may be caused by all the following except:
A) Sickle cell anemia
B) Thrombotic occlusion of a nutrient artery
C) Trauma
D) Bacteria
E) Drugs
Q2) Migratory arthritis caused by Borrelia burgdorferi is typical of:
A) Rocky Mountain spotted fever
B) Trench foot
C) Lyme disease
D) Legionnaire's disease
E) Osteoarthritis
Q3) Subcutaneous nodules composed of a central area of fibrinoid necrosis surrounded by macrophages and lymphocytes are typical of:
A) Infectious arthritis
B) Rheumatoid arthritis
C) Osteoarthritis
D) Gout
E) Rickets
To view all questions and flashcards with answers, click on the resource link above.
Page 21
Chapter 20: Muscles
Available Study Resources on Quizplus for this Chatper
22 Verified Questions
22 Flashcards
Source URL: https://quizplus.com/quiz/20539
Sample Questions
Q1) Malignant tumor of striated muscle is called:
A) Leiomyosarcoma
B) Rhabdomyosarcoma
C) Liposarcoma
D) Synovial sarcoma
E) Malignant fibrous histiocytoma
Q2) A patient with myasthenia gravis was found to have an anterior mediastinal mass.This mass proved to be a tumor.Most likely it is a:
A) Thyroid adenoma
B) Parathyroid adenoma
C) Neuroblastoma
D) Smooth muscle cell tumor
E) Thymoma
Q3) Skeletal muscles are:
A) Composed of either type I (slow)or type II (fast)fibers
B) Composed of rapidly dividing cells
C) Composed of nondividing cells that can be stimulated to enter mitosis by a variety of cytokines
D) In close contact with nerves
E) Major storage site of calcium and phosphate
To view all questions and flashcards with answers, click on the resource link above. Page 22
Chapter 21: The Nervous System
Available Study Resources on Quizplus for this Chatper
19 Verified Questions
19 Flashcards
Source URL: https://quizplus.com/quiz/20540
Sample Questions
Q1) Which of the following diseases can be transmitted by corneal transplantation?
A) Huntington's disease
B) Alzheimer's disease
C) Creutzfeldt-Jakob disease
D) Meningococcal meningitis
E) Parkinson's disease
Q2) Which of the following forms of brain injury does not cause significant macroscopic or microscopic changes in the brain?
A) Brain concussion
B) Brain contusion
C) Brain laceration
D) Coup lesion
E) Contrecoup lesion
Q3) St.Louis encephalitis is transmitted by:
A) Dust inhalation
B) Mosquito bites
C) Tick bites
D) Sexual contact
E) Kissing
To view all questions and flashcards with answers, click on the resource link above.
Page 23
Chapter 22: The Eye
Available Study Resources on Quizplus for this Chatper
13 Verified Questions
13 Flashcards
Source URL: https://quizplus.com/quiz/20541
Sample Questions
Q1) The sensory innermost layer of the eye composed of rods and cones is called:
A) Iris
B) Cornea
C) Sclera
D) Retina
E) Choroid
Q2) Allergic conjunctivitis is typically mediated by:
A) T lymphocytes
B) IgA
C) IgE
D) IgG
E) IgM
Q3) The most important complication of untreated glaucoma is:
A) Conjunctivitis
B) Keratitis
C) Iridocyclitis
D) Retinitis
E) Loss of eyesight
To view all questions and flashcards with answers, click on the resource link above.
24
Chapter 23: The Ear
Available Study Resources on Quizplus for this Chatper
10 Verified Questions
10 Flashcards
Source URL: https://quizplus.com/quiz/20542
Sample Questions
Q1) Malleus,incus,and stapes are located in the:
A) Auricle
B) Auditory canal
C) Middle ear
D) Inner ear
E) Externally to the eardrum
Q2) Which of the following tumors may cause vertigo?
A) Squamous cell carcinoma of the auricle
B) Basal cell carcinoma of the external ear
C) Schwannoma of the VIII nerve
D) Neurilemoma of the VII nerve
E) Pituitary adenoma
Q3) Tympanic cavity is part of the:
A) Auricle
B) External ear
C) Auditory meatus
D) Middle ear
E) Internal ear
To view all questions and flashcards with answers, click on the resource link above.
25