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Oral and Maxillofacial Pathology is a specialized course that explores the nature, causes, and effects of diseases affecting the oral cavity, jaws, and associated structures. The course covers the identification and microscopic features of pathological conditions, including developmental disorders, inflammatory diseases, cysts, benign and malignant tumors, and systemic diseases with oral manifestations. Emphasis is placed on correlating clinical, radiological, and histopathological findings to facilitate accurate diagnosis and management. Students develop a foundation in pathological terminology, diagnostic procedures, and the implications of disease processes on oral health, preparing them for clinical decision-making and interdisciplinary collaboration in dental practice.
Recommended Textbook
Oral pathology clinical pathologic correlations 6th edition by joseph a. regezi
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556 Verified Questions
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80 Verified Questions
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Q1) Which of the following herpesviruses is most frequently the cause of recurrent oral and perioral vesicular eruptions?
A)VZV (varicella-zoster)
B)EBV (Epstein-Barr)
C)CMV (cytomegalovirus)
D)HSV (herpes simplex), type 1
E)HSV (herpes simplex), type 2
Answer: D
Q2) Unilateral distribution of cutaneous or mucosal ulcers followed by prolonged post-lesional pain would be associated with which of the following?
A)Primary herpes simplex infection
B)Secondary herpes simplex infections
C)Secondary syphilis
D)Zoster
E)Hand-foot-and-mouth disease
Answer: D
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Q1) The symptom of pain is a consistent feature of all the following except:
A)Squamous cell carcinoma
B)Secondary herpes
C)Zoster
D)Minor aphthae
E)Acute traumatic mucosal ulcer
Answer: A
Q2) The dentist or hygienist, through careless physical contact, could contract all the following from a diseased patient (with oral lesions) except:
A)Syphilis
B)Tuberculosis
C)Squamous cell carcinoma
D)Histoplasmosis
E)San Joaquin valley fever
Answer: C
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Sample Questions
Q1) Appropriate management of geographic tongue is:
A)Observation
B)Excisional biopsy
C)Incisional biopsy
D)Nystatin therapy
E)Antidepressant medication
Answer: A
Q2) Circulating autoantibodies can be demonstrated in which of the following diseases?
A)Minor aphthae
B)Major aphthae
C)Systemic lupus erythematosus
D)Discoid lupus erythematosus
E)Recurrent herpes simplex
Answer: C
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Q1) Which of the following signs and symptoms are consistent with the diagnosis of Plummer-Vinson syndrome?
A)Arthritis, xerostomia, geographic tongue
B)Atrophic mucosa, dysphagia, anemia
C)Oral aphthae, conjunctivitis, urethritis
D)Telangiectasias, epistaxis, gingival hypertrophy
E)Mucosal pigmentation (lips), intestinal polyps
Q2) Trauma or irritation is believed to be an initiating event for which of the following?
A)Neurofibroma
B)Verruca vulgaris
C)Fibromatosis
D)Pyogenic granuloma
E)All the above
Q3) HIV-associated Kaposi's sarcoma:
A)Is typically seen in men over the age of 60 years
B)Occurs most commonly in the buccal mucosa intraorally
C)Is associated with one of the herpesviruses
D)Has an excellent prognosis
E)Presents as a painful nonhealing ulcer
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Q1) Oral mucosal lesions may exhibit a red to blue to black color for one of several reasons. These would include all the following except:
A)Increased number of submucosal vessels
B)Submucosal extravasation of blood
C)Deposition of foreign material
D)Increased thickness of epithelium
E)Hyperemia (vascular congestion)
Q2) In addition to multiple neurofibromas, what other lesions are seen as part of the syndrome neurofibromatosis?
A)Traumatic neuromas
B)Mucosal vascular malformations
C)Intestinal polyps
D)Cutaneous pigmented patches
E)Odontogenic keratocysts
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Sample Questions
Q1) Oral verrucous carcinoma:
A)Is usually treated with surgery
B)May be related to the use of smokeless tobacco
C)Is microscopically well differentiated
D)Rarely metastasizes to the lung
E)All the above
Q2) A firm asymptomatic submucosal lump, measuring 1 ´ 1 cm, appeared in the posterior hard palate of a 27-year-old man. The duration of the lesion was believed to be approximately 1 month. Clinical differential diagnosis should include all of the following except:
A)Lymphoma
B)Mucocele
C)Malignant salivary gland tumor
D)Benign salivary gland tumor
E)Squamous papilloma
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Q1) Acute leukemias, especially monocytic leukemias, may cause oral manifestations of bleeding and:
A)Generalized gingival hyperplasia
B)Mucous extravasation
C)Focal lymphoid hyperplasia
D)Melanosis
E)All the above
Q2) Pseudoepitheliomatous hyperplasia is a frequent microscopic finding of a neural-derived benign tumor in which granular cells expand submucosa. This lesion is known as:
A)Traumatic neuroma
B)Neurofibroma
C)Neurilemmoma
D)Leiomyoma
E)None of the above
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Q1) A 16-year-old patient complained of a 1 ´ 1 cm nontender mass in his upper lip. The lesion was nonulcerated and was composed of a dilated duct containing a sialolith. This would be which of the following?
A)Focal fibrous hyperplasias
B)Traumatic neuroma
C)Fibromatosis
D)Mucous extravasation phenomenon
E)None of the above
Q2) Trauma is the cause of which of the following?
A)Static (Stafne) bone cyst
B)MEN III-associated mucosal neuroma
C)Mucous extravasation phenomenon
D)Dermoid cyst
E)None of the above
Q3) Necrotizing sialometaplasia:
A)Occurs in the palate
B)May be confused with carcinoma clinically
C)May be confused with carcinoma microscopically
D)Is related to ischemic necrosis
E)All the above
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Q1) Oral extranodal lymphomas are most likely to present as ulcerated or nonulcerated masses in which of the following sites?
A)Buccal mucosa
B)Tongue
C)Palate
D)Floor of the mouth
E)Lower lip
Q2) A 25-year-old woman developed a recurrent mass in her buccal mucosa. On biopsy, the lesion was described as a benign spindle cell proliferation. All the following are consistent with this description except:
A)Fibromatosis
B)Low-grade fibrosarcoma
C)Nodular fasciitis
D)Fibrous histiocytoma
E)Lymphoma
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Q1) A 16-year-old patient was found to have a unicystic radiolucency in the body of the mandible between the roots of vital teeth nos. 28 and 29. Thin parakeratinized epithelium was found lining the cystic space on biopsy. This is a(n):
A)Lateral root cyst
B)Traumatic bone cyst
C)Odontogenic keratocyst
D)Laterally positioned periapical cyst
E)Cyst of dental lamina
Q2) The static bone cyst, if biopsied, exhibits which of the following microscopic features?
A)Virtually nothing, as it represents a dead space
B)Hematopoietic tissue
C)Fibrous tissue lined by respiratory-type epithelium
D)Salivary gland and other soft tissues that normally reside in the area
E)Granulation tissue and giant cells
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Q1) A radiolucent odontogenic tumor was composed completely of loose connective tissue. It had an appearance that had some resemblance to dental pulp. This is a(n):
A)Ameloblastoma
B)Ameloblastic fibroma
C)Odontogenic myxoma
D)Complex odontoma
E)Adenomatoid odontogenic tumor
Q2) Lung metastasis is a well-documented complication after surgical treatment of which of the following?
A)Calcifying epithelial odontogenic tumor
B)Odontogenic keratocyst
C)Odontogenic myxoma
D)Cementoblastoma
E)None of the above
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Q1) Which of the following could be classified as a benign fibro-osseous lesion?
A)Fibrous dysplasia
B)Idiopathic histiocytosis
C)Ewing's tumor
D)Odontogenic myxoma
E)Hematopoietic bone marrow defect
Q2) Patients with central giant cell granulomas typically have which of the following abnormal laboratory findings?
A)Elevated immunoglobulins
B)Elevated serum alkaline phosphatase
C)Elevated serum acid phosphatase
D)Elevated serum calcium
E)None of the above
Q3) The ossifying fibroma is characterized clinically by:
A)Slow growth
B)Well-defined borders
C)Benign fibro-osseous microscopic appearance
D)Appearance in young adults
E)All the above
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Q1) Jaw pain is a feature most often associated with:
A)Periapical granuloma
B)Periapical cemento-osseous dysplasia
C)Periapical abscess
D)Odontogenic keratocyst
E)Dentigerous cyst
Q2) A periosteal reaction consisting of concentric layering of expanding cortical bone known as "onion skin" is most often associated with which of the following?
A)Hyperparathyroidism
B)Burkitt's lymphoma
C)Garré's osteomyelitis
D)Ameloblastoma
E)Odontogenic keratocyst
Q3) Garré's osteomyelitis is usually associated with which of the following?
A)Trauma to the jaws
B)Immune dysfunction
C)Gingivitis
D)Actinomycotic infection
E)Decayed mandibular molar
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Q1) All of the following are signs or symptoms that are associated with malignancy in the jaw except:
A)Uniformly widened periodontal membrane space around a tooth (teeth)
B)Vertical tooth mobility
C)Hypercementosis
D)Premature loss of deciduous teeth
E)Acquired malocclusion
Q2) The Epstein-Barr virus may be associated with the etiology and pathogenesis of which of the following jaw lesions?
A)Garré's disease
B)Ewing's tumor
C)Burkitt's lymphoma
D)Central giant cell granuloma
E)Osteogenesis imperfecta
Q3) Osteosarcoma is known to be complication of which of the following?
A)Neurofibromatosis
B)MEN III
C)Paget's disease
D)Gardner's syndrome
E)All the above
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Q1) Impacted and supernumerary teeth are characteristically seen in which of the following?
A)McCune-Albright syndrome
B)Cleidocranial dysplasia
C)Gardner's syndrome
D)Ectodermal dysplasia
E)Regional odontodysplasia
Q2) Paget's disease:
A)Typically occurs in teenagers
B)Is caused by excessive production of growth hormone
C)Results in premature loss of teeth
D)Predisposes the patient to bone fracture and infection
E)All the above
Q3) The rare genetic disorder that results in generalized bony sclerosis is known as:
A)Cherubism
B)Plasma cell myeloma
C)von Recklinghausen's disease
D)Fibrous dysplasia
E)Albers-Schonberg disease
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Q1) Which of the following is typically associated with pulpitis and periapical inflammation following wear of a supernumerary cusp?
A)Amelogenesis imperfecta
B)Regional odontodysplasia
C)Turner's tooth
D)Dens evaginatus
E)Dens invaginatus
Q2) Serum calcium would be significantly elevated in which of the following?
A)Central giant cell granuloma
B)Cherubism
C)Ameloblastoma
D)Langerhans cell disease (idiopathic histiocytosis) of the mandible
E)None of the above
Q3) Tooth extraction is made more difficult by all the following except:
A)Paget's disease
B)Pulp stones
C)Dilaceration
D)Concrescence
E)Albers-Schonberg disease
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