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Introduction to Pharmacology offers a comprehensive overview of how drugs interact with biological systems to affect their functions. This course covers fundamental principles including drug absorption, distribution, metabolism, and excretion, as well as the molecular mechanisms of drug action. Students will explore different classes of pharmaceutical agents, their therapeutic uses, side effects, and the physiological basis for drug responses. Emphasis is placed on understanding dose-response relationships, drug-receptor interactions, and the factors that influence drug effectiveness and safety. This foundational knowledge prepares students for more advanced studies in biomedical sciences, medicine, pharmacy, and related health professions.
Recommended Textbook Essentials of Pharmacology for Health Professions 7th Edition by Ruth Woodrow
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Q1) Quinn hears on the news that the FDA has asked a company to withdraw a medication.Under what circumstances can the FDA do this?
A)when more effective alternatives are available
B)never,because only the DEA can do this
C)when it is no longer profitable
D)when the benefits of a drug outweigh its risks
Answer: D
Q2) According to your text,who is an excellent resource for you when you are unsure of your legal responsibilities with drugs or have uncertainties about drug therapy?
A)a local pharmacist
B)a DEA agent
C)a pharmaceutical sales representative
D)an attorney
Answer: A
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Q1) Drugs that relieve pain without loss of consciousness are known as .
A)anti-inflammatories
B)analgesics
C)anesthetics
D)hypnotics
Answer: B
Q2) Your friend is reading about his new medication,and asks you,"what kind of name is 8-chloro-1-methyl-6-phenyl- 4Hstriazolo [4,3 ] [1,4] benzodiazepine?" How should you respond?
A)This is the experimental name of the drug.
B)This is the chemical name of the drug.
C)This is the structural name of the drug.
D)This is the patented name of the drug.
Answer: B
Q3) Trade names are assigned by the .
A)manufacturer before development begins
B)manufacturer when the drug is first submitted to the FDA for approval
C)FDA after the drug is tested and approved
D)manufacturer after the drug has been tested and approved by the FDA
Answer: D
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Q1) Your friend has recently had a baby,and visits her doctor because of a terribly sinus infection.The doctor wants to know whether she is breastfeeding her baby.What drug process is of concern?
A)absorption
B)distribution
C)metabolism
D)excretion
Answer: B
Q2) Your cousin is started on medication after being diagnosed with epilepsy.Because he experiences seizures quite often,he starts with a very large dose of the anticonvulsant to elevate the levels of the drug in his blood as quickly as possible.This initial,large dose is known as a(n) .
A)overdose
B)loading dose
C)shock dose
D)therapeutic dose
Answer: B
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Q1) As a recovering alcoholic,you know that you should avoid taking oral medication in the form of a(n) .
A)syrup
B)solution
C)suspension
D)elixir
Q2) Tonya takes her bronchidilator using a nebulizer.What is the route of administration?
A)intraspinal
B)intravenous
C)intradermal
D)inhaled
Q3) Your back is in severe pain from helping your parents with heavy yard work all day.Your father rubs a liquid liberally on your back as treatment.You quickly notice that your skin is tingling and even burning,and realize that the medication is a(n) .
A)ointment
B)liniment
C)lotion
D)gel
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Q1) It is Connor's first day as a CNA at the nursing home and he is answering the phones on his unit.A physician calls to place a medication order.What should Connor do before he takes it?
A)Ask someone else to listen in on the conversation to make sure the order is corect.
B)Determine nursing home policy,as a registered nurse may be required to take medication orders by phone.
C)Make sure to have complete identifying information for the physician.
D)Ensure that the physician knows this is his first day as a CNA at the nursing home.
Q2) Henry is 18 months old and weighs 10 kilograms.How many pounds does he weigh?
A)22
B)12.2
C)36
D)4.5
Q3) Roxanne is told by her supervisor not to use the abbreviation "SQ." Why?
A)The use of SQ is determined by individual hospital policy.
B)SQ on the ISMP list.
C)SQ has been replaced by Sc.
D)Medicaid will not reimburse for this route.
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Q1) An order calls for 800 mg of ibuprofen and you have tablets that contain 200 mg of ibuprofen.If you use the basic method,what is Q?
A)total number of capsules
B)200 mg
C)one tablet
D)800 mg
Q2) In the basic method formula,Q refers to the .
A)conversion factor
B)ratio of the desired to the available dose
C)quantity of the on hand dose
D)quantity of the desired dose
Q3) The order calls for one ounce of rehydration fluid per hour.On hand is a solution that contains 200 grams per liter.Your first step should be to .
A)determine whether the ordered amount is reasonable
B)round to one decimal point
C)convert to the same measurement system
D)decide which computation method is most efficient
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Q1) Isaac,a spry and active 84-year-old,is hospitalized for a knee replacement.He finds it a bit insulting when nurses ask him his name before they give him his medications.Why are the nurses asking for this information?
A)To determine whether he is mentally competent
B)To ensure they are administering the right medicine to the right patient
C)To ensure he will not be given too many pain killers
D)To check his pre-surgery memory for comparison purposes
Q2) Four-year-old Patrick is at the doctor for an IM injection,and begs you to use one of the tiny needles he remembers from a skin test for allergies because that did not hurt much.What should you do?
A)Document the incident as medication refusal and do not give the shot.
B)Agree to the change but only if the molecules of the medicine will fit through the tiny lumen of the needles.
C)Agree to the change as long as he will be cooperative,as his comfort is important.
D)Carefully explain to Patrick and his parents why you cannot do this,and give the injection as ordered.
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Q1) Suppositories are especially useful .
A)when patients are reluctant to take medication
B)because they release medication at a consistent rate
C)when patients have dysphagia
D)because they ensure complete absorption
Q2) What is the term for medication in liquid form that is administered rectally?
A)retention enema
B)rectal suspension
C)enteric enema
D)suppository
Q3) If any unusual circumstances or adverse side effects are associated with medication administration,the health care practitioner should .
A)report the incident and ask your supervisor to record it
B)record the incident but only report it if the incident is potentially life-threatening
C)only record and report if the incident is is potentially life-threatening
D)record and report the incident
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Q1) Tuberculin syringes are used for .
A)administering subcutaneous fluids
B)intradermal injections of very small volumes
C)intramuscular injections
D)obtaining specimens of pulmonary secretions
Q2) What type of needles should be recapped?
A)used
B)sterile
C)all needles
D)safety
Q3) When applying a new transdermal patch,it is especially important to .
A)make sure the area it will be placed on is cleanly shaven
B)abrade the skin to facilitate absorption
C)avoid touching the inside of the patch
D)puncture the drug reservoir
Q4) Proper placement for buccal administration is .
A)in the pouch between the cheek and the gum at the back of the mouth
B)under the tongue
C)in direct contact with the nasal mucosa
D)on dry,hair-free skin

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Q1) The pediatrician has prescribed an antibiotic suspension for three-year-old Lianne.Lianne is excited that the antibiotic is bright pink and tastes like sweet bubble gum.What should her parents tell her?
A)They should express their excitement along with her.
B)They should praise her for taking her medication like a big girl.
C)They should not say anything to her,but ask for another medication that doesn't take as good.
D)They should explain that it is taken for her health and only as directed by a physician.
Q2) During a hike in the desert,your friend is bitten by a rattlesnake.You are preparing her for transport to an emergency facility.What guideline should you follow?
A)You should be sure the tourniquet is as tight as tolerable.
B)Your friend should be transported lying down.
C)The bitten area should be wrapped in a compression bandage and held above the heart.
D)You should pack the bite in ice.
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Q1) Alba has heard that vitamin D deficiency is common and has begun taking high dose supplements.What is a sign of vitamin D overdose?
A)osteomalacia
B)tetany
C)heart rhythm abnormalities
D)osteoporosis
Q2) Headache,flushing,and burning sensations of face,neck,and chest and postural hypotension are associated with high doses of .
A)thiamine
B)riboflavin
C)niacin
D)folate
Q3) The vitamin necessary for formation of intracellular substances such as collagen is vitamin .
A)A
B)D
C)C
D)E
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Q1) Marika is diabetic and has developed ulcerated sores on her foot.What type of agent is prescribed for ulcerated wounds?
A)corticosteroid
B)enzymatic
C)anti-infective
D)scabicide
Q2) Lawson,age 13 years,is experiencing mild acne and asks you,his pharmacist uncle,what to do.You suggest he look for an over-the-counter preparation containing . A)acyclovir
B)sulfur,salicylic acid,or benzoyl peroxide
C)nystatin or clortrimazole
D)lindane,ivermectin,or permethrin
Q3) The "caines," such as benzocaine,may be included in . A)antipruritics
B)enzymatics
C)retinoids
D)emollients
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Q1) Leland and his friends are in the mountains for the weekend,and collect greens,berries,and mushrooms for their final meal.Leland makes and taste tests the mushroom dish and wounds up violently ill with mushroom poisoning.At the hospital,he is treated with atropine.What side effects might Leland experience from the atropine?
A)bradycardia
B)decreased body temperature
C)diarrhea
D)blurred vision and headaches
Q2) Hadley has a terrible nose bleed and her father takes her to the urgent care center.While there,she is administered an adrenergic drug.Adrenergics may be used to treat persistent severe nose bleeds because they .
A)have a calming effect
B)constrict capillaries
C)increase blood pressure
D)slow heart rate
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Q1) Gina is taking tamoxifen to treat her metastatic estrogen receptor-positive breast cancer and is experiencing severe hot flashes.What might be prescribed to help reduce these flashes?
A)an anti-inflammatory
B)an anti-estrogen
C)an antidepressant
D)an antipyretic
Q2) Sebastian has chronic myelogenous leukemia and is being given imatinib (Gleevec).Imatinib blocks specific enzymes and growth factor receptors that affect cancer cell proliferation and belongs to the class of drugs called .
A)mitotic inhibitors
B)antitumor antibiotics
C)monoclonal antibodies
D)signal transduction inhibitors
Q3) Cheyanne has melanoma and is being treated with interferon to .
A)prevent nausea and vomiting
B)boost her immune system response
C)halt tumor growth
D)prevent proliferation of cancer cells
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Q1) Kayley has all of the symptoms of a urinary tract infection over a holiday weekend.She recalls that in the past,the urinary analgesic,phenazopyridine,has relieved her symptoms very quickly,so she asks a friend to pick some up for her rather than braving a crowded health clinic.As before,Kayley gets rapid relief of her symptoms.Should Kayley be concerned about anything else?
A)Yes.Phenazopyridine treats the symptoms,but will not cure the infection,so she still needs to see her doctor.
B)Possibly.If the infection was caused by bacteria,she will be fine,but if it was caused by a virus,she will need to see her doctor.
C)No.If the phenazopyridine has alleviated the symptoms,she should be just fine.
D)Possibly.If she experiences a return of symptoms after taking the phenazopyridine for a week,she should see her doctor.
Q2) Erin has cirrhosis.What diuretic is often recommended for patients with cirrhosis?
A)metolazone
B)spironolactone
C)mannitol
D)bumetanide
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Q1) Pedro is stunned when he suddenly becomes violently dizzy,falls against the wall,and is nauseated.His doctor rules out infections and other possible causes and diagnoses Pedro with vertigo.What antiemetic is indicated for use with vertigo?
A)dimenhydrinate
B)meclizine
C)mesalamine
D)lubiprostone
Q2) Emilee will start chemotherapy for cancer next week.She knows the agents she will be given typically produce severe nausea and vomiting.What type of antiemetic is indicated for prevention and treatment of chemotherapy- induced nausea and vomiting?
A)anticholinergics
B)serotonin receptor antagonists
C)meclizine and related drugs
D)antidopaminergics
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Q1) Four-year-old Phebian has life-threatening septicemia and the antibiotics that have been tried so far have failed.The doctors propose trying another type of antibiotic,but warn Phebian's parents that there are very serious potential adverse reactions,including nephrotoxicity,which is usually reversible,and ototoxicity,which may be permanent.This antibiotic is likely to be in which class?
A)aminoglycosides
B)penicillins
C)cephalosporins
D)macrolides
Q2) Demetrius is HIV positive and is being treated with highly active antiretroviral therapy.One of the agents he takes has caused his cheeks to sink,while fat accumulates on the back of his neck.He has also developed hyperlipidemia and diabetes mellitus.What class of drugs has this side effect profile?
A)fusion inhibitors
B)nucleoside reverse transcriptase inhibitors
C)antiretroviral protease inhibitors
D)non-nucleoside reverse transcriptase inhibitors
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Q1) Jalen has glaucoma and a miotic has been prescribed.The physician explains to Jalen that miotics act by .
A)decreasing aqueous humor production
B)increasing aqueous humor production
C)decreasing aqueous humor outflow
D)increasing aqueous humor outflow
Q2) Alfred is taking an alpha agonist to treat his glaucoma.What is especially important for him to know?
A)The medication is likely to cause postural hypotension and he should use caution in rising.
B)The medication often causes shortness of breath,so exercise should be restricted.
C)The medication may cause drowsiness and he should be careful when engaging in hazardous activities.
D)The medication can have a potentially fatal interaction with caffeine.
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Q1) Rachel is being treated for opioid addiction with a medication that combines both a pure opioid agonist and a partial opioid agonist.What is it?
A)Suboxone
B)Narcan
C)ReVia
D)Stadol
Q2) Nathan loves running long distances and often describes his runner's high.The phenomenon of runner's high is associated with the body's production of . A)endorphins
B)androgens
C)catecholamines
D)histamines
Q3) Thaddeus has shooting,shock-like pain from shingles (herpes zoster).What Schedule V second-generation anticonvulsant might be used as an adjuvant?
A)carbamazepine
B)lamotrigine
C)gabapentin
D)pregabalin
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Q1) Adrian's mother and father have personal and family histories of drug addiction.Therefore,Adrian's mother asks whether there are any nonstimulant medications that can be used to treat his ADHD.What drug might be suggested?
A)caffeine citrate
B)atomoxetine
C)methylphenidate
D)modafinil
Q2) Seven-year-old Grant's family and physician are considering pharmacologic treatment of his ADHD with one of the amphetamine/methylphenidate formulations.Accordingly,it is particularly important that the physician screen for personal and family history of .
A)hypothyroidism
B)cardiovascular disease
C)cancer
D)diabetes
Q3) Newborn Giana has sleep apnea.The medication of choice is .
A)methylphenidate
B)caffeine citrate
C)pseudoephedrine
D)lisdexamfetamine
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Q1) Jeremy has painful muscle spasms associated with rheumatoid arthritis.He knows that his friend Tanya,who has multiple sclerosis,has experienced relief from her muscle spasms with dantrolene.Is dantrolene also appropriate for Jeremy?
A)Dantrolene should also be used if the spasms are severe.
B)Dantrolene should only be used as a last choice medication when other agents have failed.
C)Yes.It is very likely Jeremy will have a good effect from dantrolene.
D)No.Dantrolene is not indicated for muscle spasms associated with rheumatic conditions.
Q2) For years,the only medication Jayla has taken to help with her severe knee pain is an NSAID.She has just been diagnosed with cancer and is to be treated with,among other agents,methotrexate.What is the potential interaction between the methotrexate and the NSAID?
A)decreased effectiveness of methotrexate
B)potentiation and increased risk of methotrexate toxicity
C)decreased effectiveness of the NSAID
D)potentiation and increased risk of adverse effects of the NSAID
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Q1) Thelma has restless leg syndrome that has disrupted her sleep and left her drowsy during the day.What medication might be helpful?
A)levodopa
B)selegiline
C)pramipexole
D)benztropine
Q2) Kody takes a broad-spectrum anticonvulsant,which is likely to be .
A)clonazepam
B)valproic acid
C)ethosuximide
D)carbamazepine
Q3) Jane has sensorimotor neurologic disorder characterized by a distressing urge to move the legs,often accompanied by a marked sense of discomfort in the legs.She likely has .
A)ALS
B)RLS
C)Parkinson's
D)psychomotor epilepsy
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Q1) Your friend Kaylin has been diagnosed with Type 1 diabetes and you take part in her diabetes education classes to learn more.What symptoms might indicate that Kaylin is hyperglycemic?
A)ravenous appetite
B)tachycardia
C)decreased urine production
D)fruity breath
Q2) Routine newborn testing reveals that Kassandra has congenital hypothyroidism.If congenital hypothyroidism is untreated,Kassandra might develop .
A)cognitive disabilities
B)hearing loss
C)vision loss
D)hyperactivity disorder
Q3) Ayla has a severe allergic reaction and is treated with corticosteroids.What gland produces corticosteroids?
A)adrenal
B)pituitary
C)islets of Langerhans
D)thyroid
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Q1) Magdalena is 27 weeks pregnant with twins and is showing signs of labor.What medication might she be given to manage her preterm labor?
A)misoprostol
B)carboprost
C)terbutaline
D)methylergonovine
Q2) Abigail just started taking oral contraceptives.How long should she use backup contraception?
A)1 week
B)3 weeks
C)4 weeks
D)2 weeks
Q3) Simone has decided to take combined estrogen-progestin therapy (EPT).How long can she take it before her risk of breast cancer will increase?
A)more than 10 years
B)1 to 2 years
C)3 to 5 years
D)6 to 8 years
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Q1) What antiarrythmic agent has local anesthetic effects,direct stabilizing action on myocardial membranes,and beta- adrenergic blocking properties?
A)propafenone
B)procainamide
C)verapamil
D)amiodarone
Q2) Davina is rushed to the hospital shortly after she begins to experience symptoms of what is diagnosed as an ischemic stroke.What agent can be administered that will dissolve the clot?
A)ticagrelor
B)altephase
C)prasugrel
D)dipyridamole
Q3) Ginny has hypertension and is taking an ACE inhibitor.How do ACE inhibitors work?
A)By slowing heart rate
B)By increasing cardiac output
C)By decreasing vasoconstriction
D)By stabilizing the heart membrane
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Q1) Iona uses an inhaler that delivers her medication through the compression of a valve.What kind of inhaler does she use?
A)metered dose inhaler
B)dry-powder inhaler
C)intranasal inhaler
D)small volume nebulizer
Q2) Justin has come to the conclusion that caring for a three-year-old with a bad cold is far more challenging than calculus.He wonders if one of the over-the-counter cold medicines might help.Would an OTC cold medicine help?
A)Absolutely.An OTC cold medicine will be helpful.
B)No.There is no proof that these medications ease cold symptoms in children.
C)Yes,if he follows the label directions exactly.
D)The medication might or might not help,depending on what ingredients are included.
Q3) Short-acting beta agonists are .
A)antihistamines
B)maintenance medications
C)antitussives
D)rescue medications
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Q1) Mandatory retirement at age 72 has left Devon in a prolonged depression,and his doctor suggests an antidepressant.Would imipramine be a good choice for him?
A)No.Imipramine has significant anticholinergic action and is inappropriate.
B)Possibly,but it depends on what other medications Devon is taking.
C)Yes.Imipramine is safe and effective for elderly individuals.
D)Yes,but only if psychotherapy does not help Devon.
Q2) Cristobal,age 79,has early renal failure.What type of medication is especially dangerous to him because of its nephrotoxic effects?
A)OTC antacids
B)aminoglycosides
C)benzodiazepines
D)OTC antitussives
Q3) Ernest,72 years of age,has less muscle and more fat than he had when younger.What process will that affect?
A)absorption
B)distribution
C)excretion
D)metabolism
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