Histology Question Bank
Course Introduction
Histology is the study of the microscopic structure of tissues and cells in plants and animals. This course provides a comprehensive overview of the organization, function, and identification of the four basic tissue types epithelial, connective, muscle, and nervous tissue using light and electron microscopy. Students will learn to recognize normal tissue architecture, relate structural features to physiological roles, and understand the relationship between tissue pathology and disease processes. Laboratory sessions emphasize slide preparation, staining techniques, and microscopic analysis to develop practical skills essential for careers in medicine, biology, and biomedical research.
Recommended Textbook
Histology and Cell Biology An Introduction to Pathology 3rd Edition by Abraham L Kierszenbaum
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23 Chapters
246 Verified Questions
246 Flashcards
Source URL: https://quizplus.com/study-set/1202 Page 2
Chapter 1: Epithelium
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18 Verified Questions
18 Flashcards
Source URL: https://quizplus.com/quiz/23777
Sample Questions
Q1) The apical surface modifications of the cells lining the small intestine contain which of the following proteins?
A) Actin
B) Claudin
C) Elastin
D) Myosin
E) Occludin
Answer: A
Q2) Which of the following proteins composes the majority of the basal lamina?
A) Collagen
B) Fibrin
C) Fibronectin
D) Integrin
E) Laminin
Answer: E
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Page 3
Chapter 2: Epithelial Glands
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6 Verified Questions
6 Flashcards
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Sample Questions
Q1) Which of the following is the site of steroid hormone synthesis?
A) Golgi apparatus
B) Mitochondria
C) Ribosomes
D) Rough endoplasmic reticulum
E) Smooth endoplasmic reticulum
Answer: E
Q2) The mode of exocrine gland secretion in which the secretory product is released in a pinched-off piece of the plasma membrane is
A) Apocrine
B) Eccrine
C) Endocrine
D) Holocrine
E) Merocrine
Answer: A
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Chapter 3: Cell Signaling
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6 Verified Questions
6 Flashcards
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Sample Questions
Q1) A secreted chemical messenger meant to act on an adjacent cell is called a(n)
A) Autocrine
B) Hormone
C) Neurohormone
D) Neurotransmitter
E) Paracrine
Answer: E
Q2) Which of the following functions by diffusing across the cell membrane to bind to intracellular protein receptors, resulting in gene activation or repression?
A) Acetylcholine
B) Insulin
C) Nitric oxide
D) Prostaglandin
E) Testosterone
Answer: E
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Page 5
Chapter 4: Connective Tissue
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23 Verified Questions
23 Flashcards
Source URL: https://quizplus.com/quiz/23780
Sample Questions
Q1) The type of cartilage found in the external ear is
A) Aurocartilage
B) Elastic cartilage
C) Fibrocartilage
D) Hyaline cartilage
E) Otocartilage
Q2) Which characteristic is true of BOTH brown and white fat?
A) Cells feature multiple fat-storing vesicles
B) Cells have flattened, peripheral nuclei
C) They are found in the neck and the interscapular region in infants
D) Both are highly vascular
E) Their principal role is in providing cushioning for organs
Q3) Both mature bone cells and mature cartilage cells are found in chambers called
A) Isogenous groups
B) Lacunae
C) Lamellae
D) Territorial matrices
E) Volkmann's canals
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Chapter 5: Osteogenesis
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10 Verified Questions
10 Flashcards
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Sample Questions
Q1) What occurs in the hypertrophic zone during endochondral ossificiation?
A) Chondrocytes in the center of the cartilage undergo mitosis and growth
B) Invasion of empty lacunae by osteoprogenitor cells
C) Penetration of calcified septa by blood vessels
D) Programmed cell death of chondrocytes
E) Proliferating chondrocytes organize into parallel columns
Q2) Each of the following statements about epiphyseal plates is correct EXCEPT
A) Appositional growth occurs on the epiphyseal side
B) Bone replaces cartilage on the diaphyseal side
C) Mitotically active chondrocytes are distributed throughout the zone of reserve cartilage
D) These chondrocytes are required for lengthening of long bones
E) They contain a portion of healthy hyaline cartilage
Q3) Each of the following statements about epiphyseal plates is correct EXCEPT
A) Appositional growth occurs on the epiphyseal side
B) Bone replaces cartilage on the diaphyseal side
C) Mitotically active chondrocytes are distributed throughout the zone of reserve cartilage
D) Epiphyseal plates are required for lengthening of long bones
E) Epiphyseal plates contain a portion of healthy hyaline cartilage
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Chapter 6: Blood and Hematopoiesis
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14 Verified Questions
14 Flashcards
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Sample Questions
Q1) Where is the primary site of hemopoiesis?
A) Adipose tissue
B) Blood vessels
C) Bone marrow
D) Liver
E) Lymph nodes
Q2) Which cell type gives rise to platelets (thrombocytes)?
A) Megakaryocyte
B) Monoblast
C) Monocyte
D) Myeloblast
E) Thromboblast
Q3) Erythropoietin
A) Blocks the production of red blood cells
B) Inhibits blood clotting
C) Is a hormone released by the pituitary gland
D) Stimulates red blood cell destruction in the spleen
E) Stimulates red blood cell production in the bone marrow
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8
Chapter 7: Muscle Tissue
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9 Verified Questions
9 Flashcards
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Sample Questions
Q1) Which of the following is NOT a structural component of a triad?
A) Myofibril
B) Sarcolemma
C) Sarcoplasmic reticulum
D) Terminal cisterna
E) Transverse tubule
Q2) All of the following occur during the contraction of a sarcomere except
A) Shortening of A-band
B) Shortening of H-zone
C) Shortening of I-band.
D) Thin filaments slide toward M-line
E) Z-lines move closer together
Q3) The structure that serves as an attachment for thin filaments and demarcates the boundary between sarcomeres in skeletal muscle is the
A) A band
B) H zone
C) I band
D) M line
E) Z line
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Page 9
Chapter 8: Nervous Tissue
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9 Verified Questions
9 Flashcards
Source URL: https://quizplus.com/quiz/23784
Sample Questions
Q1) The neuroglial cells responsible for myelinating axons in the central nervous system are
A) Astrocytes
B) Ependymal cells
C) Microglial cells
D) Oligodendrocytes
E) Schwann cells
Q2) Cell bodies of which of the following type of neuron are found in dorsal root ganglia?
A) Central nervous system
B) Parasympathetic nervous system
C) Sensory
D) Somatic motor
E) Sympathetic
Q3) Interneurons are found
A) Only in the brain
B) Only in the central nervous system
C) Only in the peripheral nervous system
D) Only in the spinal cord
E) Throughout the nervous system
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Page 10
Chapter 9: Sensory Organs: Vision and Hearing
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10 Verified Questions
10 Flashcards
Source URL: https://quizplus.com/quiz/23785
Sample Questions
Q1) Which of the following components prevents the aqueous humor from infiltrating the cornea?
A) Bowman's layer
B) Corneal endothelium
C) Corneal epithelium
D) Descemet's membrane
E) Stroma
Q2) The basal laminae of the retinal epithelium and underlying choriocapillaris endothelium as well as layers of collagen and elastic fibers make up the _____ of the choroid
A) Bruch's membrane
B) Choroidal stroma
C) Descemet's membrane
D) Drusen
E) Sclera
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Chapter 10: Immune-Lymphatic System
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8 Verified Questions
8 Flashcards
Source URL: https://quizplus.com/quiz/23786
Sample Questions
Q1) The major histocompatibility complex
A) Activates B cells to produce specific antibodies
B) Differentiates into cytotoxic T cells upon re-exposure to a known pathogen
C) Helps T cells recognize antigens as nonself
D) Recognizes and kills viral cells by secreting perforin
E) Secretes interferon on contact with a virus
Q2) When a child develops measles and acquires immunity to a subsequent infection, this type of immunity is called
A) Adaptive immunity
B) Artificial immunity
C) Inherited immunity
D) Natural immunity
E) Passive immunity
Q3) Helper T cells
A) Activate B cells to produce specific antibodies
B) Differentiate into cytotoxic T cells upon re-exposure to a known pathogen
C) Help T cells recognize antigens as nonself
D) Recognize and kill viral cells by secreting perforin
E) Secrete interferon upon contact with a virus
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Page 12
Chapter 11: Integumentary System
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11 Verified Questions
11 Flashcards
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Sample Questions
Q1) These cells are responsible for producing a pigment that protects underlying tissue from ultraviolet radiation
A) Basal (satellite) cells
B) Keratinocytes
C) Langerhans cells
D) Melanocytes
E) Merkel cells
Q2) Which of the following epidermal layers is closest to the dermis?
A) Stratum corneum
B) Stratum germinativum
C) Stratum granulosum
D) Stratum lucidum
E) Stratum spinosum
Q3) The _____ is a vascularized, innervated structure where new hair growth occurs
A) Arrector pili
B) Dermal papilla
C) Hair follicle
D) Hair root plexus
E) Hair shaft
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Chapter 12: Cardiovascular System
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12 Verified Questions
12 Flashcards
Source URL: https://quizplus.com/quiz/23788
Sample Questions
Q1) Lymphatic vessels
A) Are open-ended
B) Eventually drain into one of the subclavian veins
C) Have fewer valves than veins
D) Have simple squamous epithelial cells separated by tight junctions
E) Merge with capillary networks throughout the body
Q2) Pericytes are found in association with
A) Arterioles
B) Capillaries
C) Elastic arteries
D) Muscular arteries
E) Veins
Q3) Arteries are best described as
A) Thick-walled vessels that carry blood toward the heart
B) Thick-walled vessels that carry oxygenated blood
C) Thin-walled vessels that carry blood away from the heart
D) Thin-walled vessels that carry deoxygenated blood
E) Not one of the above is an accurate description of arteries
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Chapter 13: Respiratory System
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11 Verified Questions
11 Flashcards
Source URL: https://quizplus.com/quiz/23789
Sample Questions
Q1) Which of the following statements about the larynx is not true?
A) It is lined with respiratory epithelium
B) The false vocal folds contain the space of Reinke
C) The subglottis is inferior to the anterior and posterior commissures
D) The true vocal folds are found in the glottis
E) Vocal cords are abducted during inspiration
Q2) Which respiratory structure constitutes the last part of the conducting zone?
A) Alveolar ducts
B) Primary bronchi
C) Respiratory bronchioles
D) Secondary bronchi
E) Terminal bronchioles
Q3) Which of the following cells in the olfactory epithelium are structurally bipolar neurons?
A) Basal cells
B) Bowman's cells
C) Columnar cells
D) Olfactory cells
E) Sustentacular cells
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Page 15
Chapter 14: Urinary System
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14 Verified Questions
14 Flashcards
Source URL: https://quizplus.com/quiz/23790
Sample Questions
Q1) Structural support in the renal corpuscle is provided by the
A) Basal lamina
B) Filtration slit diaphragms
C) Mesangium
D) Pedicles
E) Podocytes
Q2) Podocytes comstitute the ____ of the renal corpuscle
A) Basal lamina
B) Glomerulus
C) Inner visceral layer of Bowman's capsule
D) Mesangium
E) Outer parietal layer of Bowman's capsule
Q3) The renin-angiotensin system is controlled by the A) Afferent arteriole
B) Bowman's capsule
C) Glomerulus
D) Juxtaglomerular apparatus
E) Loop of Henle
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16
Chapter 15: Upper Digestive Segment
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15 Verified Questions
15 Flashcards
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Sample Questions
Q1) What do the surface mucous cells of the stomach do?
A) They are regenerative
B) They help reabsorb vitamin B12
C) They secrete a substance that protects the stomach lining from acid
D) They secrete hydrochloric acid
E) They secrete into the base of the gastric pit
Q2) The secretion of which cell type is needed to begin the process of digesting proteins?
A) Chief cells
B) Gastroenteroendocrine cells
C) Mucous neck cells
D) Parietal cells
E) Stem cells
Q3) The outer surface of the tooth's root is covered by _____.
A) Cementum
B) Dentin
C) Enamel
D) Gingivae
E) Pulp
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Page 17
Chapter 16: Lower Digestive Segment
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9 Verified Questions
9 Flashcards
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Sample Questions
Q1) Which of the following is characteristic of the ileum but not of the duodenum or jejunum?
A) Brunner's glands
B) Leaf-shaped villi
C) Glandless submucosa
D) Paneth cells
E) Peyer's patches
Q2) Fat-filled pouches in the large intestinal adventitia are called
A) Appendices epiploicae
B) Peyer's patches
C) Plicae circulares
D) Rugae
E) Taeniae coli
Q3) The ____ secrete(s) an alkaline fluid to protect the duodenum from acidic chyme.
A) Brunner's glands
B) Gallbladder
C) Goblet cells
D) Liver
E) Peyer's patches
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Page 18
Chapter 17: Digestive Glands
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13 Verified Questions
13 Flashcards
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Sample Questions
Q1) Portal triads are made up of vessels carrying all of the following EXCEPT
A) Bile away from the liver cells
B) Deoxygenated blood away from the liver cells
C) Deoxygenated blood to the liver cells
D) Nutrient-rich blood to the liver cells
E) Oxygenated blood to the liver cells
Q2) Which of the following is not true of pancreatic intercalated ducts?
A) The secretory acini empty their secretions into them
B) Their initial segments are formed by centroacinar cells
C) They are lined by low columnar or cuboidal epithelium
D) They empty into interlobular ducts
E) They receive secretions from the duct of Wirsung
Q3) Digestive enzymes such as trypsin and cholesterol esterase are secreted by the
A) Cardiac glands
B) Islets of Langerhans
C) Liver
D) Pancreatic secretory acini
E) Principal ("true") gastric glands
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19
Chapter 18: Neuroendocrine System
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7 Flashcards
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Sample Questions
Q1) The hormone that stimulates insulin-like growth factor-1 production in the hepatocytes is secreted by
A) Acidophils
B) Basophils
C) Chromophobe cells
D) Herring bodies
E) Pituicytes
Q2) Prolactin secretion is _____ by _____.
A) Inhibited dopamine
B) Inhibited somatostatin
C) Stimulated dopamine
D) Stimulated growth hormone-releasing hormone
E) Stimulated nerve impulse from the hypothalamus
Q3) The anterior pituitary
A) Has a blood-brain barrier generated by pituicytes
B) Is composed of basophils, acidophils, and chromophobe cells
C) Is made up of the pars nervosa and the infundibulum
D) Receives blood from the inferior hypophyseal artery
E) Secretes hormones when directed to do so by a nervous signal from the hypothalamus
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Chapter 19: Endocrine System
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9 Verified Questions
9 Flashcards
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Sample Questions
Q1) Sodium and water retention in the kidney is stimulated by a hormone secreted by
A) Chromaffin cells
B) Islets of Langerhans
C) Zona fasciculata
D) Zona glomerulosa
E) Zona reticularis
Q2) The zona reticularis of the adrenal cortex produces
A) Androgens
B) Corticoids
C) Glucocorticoids
D) Mineralocorticoids
E) Steroids
Q3) The trophic hormone that controls the release of T4 (thyroxine) and T3 (triiodothyronine) is secreted by
A) Acidophilic cells
B) Basophilic cells
C) Chromaffin cells
D) Chromophobic cells
E) Follicular cells
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Page 21
Chapter 20: Spermatogenesis
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8 Verified Questions
8 Flashcards
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Sample Questions
Q1) Spermatogenic cells and Sertoli cells are found in the
A) Epididymides
B) Prostate
C) Rete testes
D) Seminiferous tubules
E) Vas deferens
Q2) Diploid spermatogenic cells in direct contact with the basal lamina are
A) Sertoli cells
B) Spermatocytes
C) Spermatogenic cells
D) Spermatogonia
E) Spermatozoa
Q3) Which of the following is not true of Sertoli cells?
A) Their function is regulated by follicle-stimulating hormone
B) They are found in testicular interstitial tissue
C) They prevent cytotoxic agents from moving to the seminiferous tubules from the blood by forming tight junctions with adjacent Sertoli cells
D) They provide mechanical support for spermatogenic cells
E) They provide nutrition for spermatogenic cells
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Page 22
Chapter 21: Sperm Transport and Maturation
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6 Verified Questions
6 Flashcards
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Sample Questions
Q1) Sperm move from the tubuli recti into the
A) Ductuli efferentes
B) Epididymidis
C) Rete testis
D) Seminiferous tubules
E) Vas deferens
Q2) Which duct has a characteristic wavy lumen as a result of different epithelial cell heights?
A) Ductuli efferentes
B) Ductus epididymidis
C) Rete testis
D) Seminiferous tubules
E) Tubuli recti
Q3) What structure contributes a lubricating mucus substance to semen?
A) Bulbourethral gland
B) Epididymidis
C) Prostate
D) Seminal vesicle
E) Testis
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Chapter 22: Follicle Development and the Menstrual Cycle
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Sample Questions
Q1) Which of the following does not occur as a result of the luteinizing hormone surge?
A) Formation of the corpus luteum
B) Increased estrogen secretion
C) Ovulation
D) Secondary oocyte completes meiosis I
E) Secretion of proteolytic enzymes from the mature follicle
Q2) Which ovarian follicle has a simple cuboidal epithelium?
A) Mature follicle
B) Primary follicle
C) Primordial follicle
D) Secondary follicle
E) Both B and D have simple cuboidal epithelia
Q3) Developing follicles are found in the
A) Ovarian cortex
B) Ovarian medulla
C) Oviduct
D) Tunica albuginea
E) Uterus
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Chapter 23: Fertilization, Placentation, and Lactation
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8 Verified Questions
8 Flashcards
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Sample Questions
Q1) What structure secretes estrogen and progesterone for approximately 3 months following fertilization?
A) Corpus albicans
B) Corpus luteum
C) Mature follicle
D) Placenta
E) Tunica albuginea
Q2) Rapid cell division without organismal growth is called
A) Cleavage
B) Implantation
C) Meiosis
D) Mitosis
E) Oogenesis
Q3) Which part of the spermatozoa contains digestive enzymes that aid in fertilization?
A) Acrosome
B) Basal plate
C) End piece
D) Neck
E) Tail
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Page 25