Health Sciences
Study Guide Questions
Course Introduction
Health Sciences is an interdisciplinary field that explores the application of scientific principles to the promotion, maintenance, and improvement of human health. This course examines the biological, behavioral, and social factors that influence health and disease, while also introducing students to healthcare systems, preventative medicine, epidemiology, public health policies, and emerging technologies in health care. Through an integrative approach combining theory, research, and practical case studies, students develop a foundational understanding of the scientific and ethical issues that drive advancements in health, preparing them for a variety of careers in healthcare, research, and policy development.
Recommended Textbook
Basic and Applied Concepts of Blood Banking and Transfusion Practices 3rd Edition by Kathy D.
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16 Chapters
465 Verified Questions
465 Flashcards
Source URL: https://quizplus.com/study-set/1947 Page 2
Chapter 1: Immunology: Basic Principles and Applications in the Blood Bank
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40 Verified Questions
40 Flashcards
Source URL: https://quizplus.com/quiz/38804
Sample Questions
Q1) Has the highest number of antigen binding sites
A)IgA
B)IgM
C)IgG
D)IgE
Answer: B
Q2) A patient's record indicated that he had a history of an antibody to HPA-1a.What is the significance of this antibody if this patient requires a platelet transfusion?
A)The patient would require HPA-1a negative platelets,which are relatively rare.
B)Transfusion of HLA-matched platelet donors would yield a better response.
C)Washed platelets are necessary to avoid antibody interference.
D)No testing is necessary because the frequency of HPA-1a positive donors is very rare.
Answer: A
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3
Chapter 2: Blood Banking Reagents: Overview and Applications
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34 Verified Questions
34 Flashcards
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Sample Questions
Q1) Which of the following statements is true regarding high-protein anti-D reagents?
A)They have been largely replaced with low-protein monoclonal reagents.
B)They contain approximately 20% bovine albumin.
C)They may increase the possibility of a false-positive reaction,requiring the use of a control.
D)All of the above are true.
Answer: D
Q2) What immunoglobulin class reacts best by antiglobulin testing?
A)IgM
B)IgA
C)IgE
D)IgG
Answer: D
Q3) The indirect antihuman globulin test is incubated at what temperature?
A)22° C
B)37° C
C)4° C
D)56° C
Answer: B
Page 4
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Chapter 3: Genetic Principles in Blood Banking
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32 Verified Questions
32 Flashcards
Source URL: https://quizplus.com/quiz/38806
Sample Questions
Q1) In the PCR reaction,short pieces of single-stranded DNA that are complementary and mark the sequence to be amplified are called:
A)nucleotides.
B)polymerases.
C)primers.
D)amplicons.
Answer: C
Q2) Having two or more alleles at a given gene locus
A)Haplotypes
B)Recessive
C)Amorphic genes
D)Codominant genes
E)Polymorphic
Answer: E
Q3) A person whose red cells type as M+N+ with antisera would be:
A)a homozygote.
B)a heterozygote.
C)unable to be determined without family studies.
D)linked.
Answer: B
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Chapter 4: Abo and H Blood Group Systems and Secretor
Status
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25 Verified Questions
25 Flashcards
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Sample Questions
Q1) A blood sample from a 90-year-old man was submitted to the blood bank for a type and screen before surgery.The forward type demonstrates as a group A,whereas the reverse type appears to be group AB.The most likely cause of the discrepancy is:
A)contaminated reagent antisera.
B)rouleaux formation.
C)that the patient has autoantibodies.
D)that patient has low-titer isoagglutinins.
Q2) A patient's red cells are agglutinated by anti-B,but not by anti-A.This person would have which of the following ABO phenotypes?
A)Group B
B)Group O
C)Group AB
D)Group A
Q3) What ABO phenotype would agglutinate in the presence of anti-A,B produced by group O individuals?
A)A only
B)B only
C)A and B
D)O only
Page 6
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Chapter 5: Rh Blood Group System
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) An anti-E was identified in a patient who recently received a transfusion.What other Rh system antibody should be investigated?
A)Anti-G
B)Anti-f
C)Anti-D
D)Anti-c
Q2) R<sup>z</sup>
A)Ce
B)CE
C)DCE
D)Dce
Q3) The inheritance of the Rh antigens are:
A)X-linked recessive.
B)X-linked dominant.
C)autosomal recessive.
D)codominant.
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Chapter 6: Other Blood Group Systems
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27 Verified Questions
27 Flashcards
Source URL: https://quizplus.com/quiz/38809
Sample Questions
Q1) Which of the following phenotypes is heterozygous?
A)Fy(a-b+)
B)Jk(a+b-)
C)Fy(a+b+)
D)Le(a+b-)
Q2) Antigens Yt<sup>a</sup> and Yt<sup>b</sup> are in this system
A)Cartwright
B)MNSs
C)Kidd
D)Vel
E)Xg<sup>a</sup>
F)Sd<sup>a</sup> antigen
G)Chido/Rodgers
H)Kell
I)Duffy
Q3) A person who inherits the Le,Se,and H genes will have red cells that phenotype:
A)Le(a+b+).
B)Le(a-b+).
C)Le(a-b-).
D)Le(a+b-).
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Chapter 7: Antibody Detection and Identification
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30 Verified Questions
30 Flashcards
Source URL: https://quizplus.com/quiz/38810
Sample Questions
Q1) All the following antigens are commonly found on screening cells except: A)D.
B)k.
C)Kp<sup>a</sup>.
D)C.
Q2) The best description of the elution technique is that it is a technique used to:
A)disassociate IgM antibodies from red cells for further identification.
B)disassociate IgG antibodies from red cells for further identification.
C)adsorb IgG antibodies from serum.
D)separate IgG and IgM antibodies in serum.
Q3) In an antibody identification panel,only one red cell was negative at the antihuman globulin phase.On ruling out and matching the pattern,an anti-k was identified.What further testing is necessary to confirm the antibody?
A)Two more k-negative cells should be tested.
B)Two more K-negative cells should be tested.
C)Treat the panel cells with enzymes and perform the panel again.
D)Perform an adsorption using "k"-positive cells.
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Page 9
Chapter 8: Compatibility Testing
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30 Verified Questions
30 Flashcards
Source URL: https://quizplus.com/quiz/38811
Sample Questions
Q1) To increase the sensitivity of the antibody screen in a compatibility test,what can be done?
A)Extend the incubation time.
B)Increase the serum-to-cell ratio.
C)Use an enhancement such as polyethylene glycol.
D)All of the above are correct.
Q2) Which of the following tests is not included in routine compatibility testing?
A)ABO phenotyping
B)Direct antiglobulin test
C)D typing
D)Antibody screen
Q3) The immediate spin or abbreviated crossmatch is an acceptable procedure if the recipient:
A)has no prior or existing clinically significant antibodies.
B)has never been pregnant or transfused.
C)needs blood before a sample can be obtained.
D)is using blood from a directed donation.
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Chapter 9: Blood Bank Automation for Transfusion Services
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10 Verified Questions
10 Flashcards
Source URL: https://quizplus.com/quiz/38812
Sample Questions
Q1) The PROVUE,TANGO,and NEO have the ability to perform all of the following tests except:
A)ABO/D typing.
B)antibody ID panels.
C)direct antiglobulin test.
D)None of the above are correct.
Q2) Random access is an important feature in selecting an automated instrument for testing in the transfusion service.Random access refers to:
A)ability of multiple users to sign into the system.
B)the recognition of various types of barcodes.
C)the need for minimal maintenance procedures.
D)the ability to accommodate STAT testing.
Q3) Before implementing new automation technology into the transfusion service setting,which of the following is required?
A)Validation
B)Training
C)Written procedures
D)All of the above
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Chapter 10: Adverse Complications of Transfusions
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30 Verified Questions
30 Flashcards
Source URL: https://quizplus.com/quiz/38813
Sample Questions
Q1) The clinical sequelae of a hemolytic transfusion reaction may include all of the following except:
A)disseminated intravascular coagulation.
B)renal failure.
C)shock.
D)graft-versus-host disease.
Q2) A 44-year-old woman has a hemoglobin level of 6.1 g/dL.White blood cell and platelet counts are within normal levels.The patient is group O D-negative with a negative antibody screen.Crossmatches are compatible.However,15 minutes after the first transfusion is started,she experiences erythema and hives.What type of transfusion reaction is occurring?
A)Urticarial
B)Febrile nonhemolytic
C)Delayed hemolytic
D)Acute hemolytic
Q3) In a delayed hemolytic transfusion reaction,the DAT is typically:
A)negative.
B)positive due to C3.
C)mixed field positive.
D)very strongly positive.
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Chapter 11: Hemolytic Disease of the Fetus and Newborn
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30 Verified Questions
30 Flashcards
Source URL: https://quizplus.com/quiz/38814
Sample Questions
Q1) A .3% fetomaternal bleed was determined by a Kleihauer Betke stain of postpartum blood.What is the estimated volume of the fetomaternal bleed expressed as whole blood?
A)10 mL
B)15 mL
C)20 mL
D)25 mL
Q2) What immunoglobulin is capable of crossing the placenta?
A)IgA
B)IgG
C)IgM
D)IgE
Q3) In which type of hemolytic disease of the fetus and newborn is the first-born affected?
A)ABO
B)D
C)E
D)M
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13
Chapter 12: Donor Selection and Phlebotomy
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30 Verified Questions
30 Flashcards
Source URL: https://quizplus.com/quiz/38815
Sample Questions
Q1) How often can a person donate a unit of whole blood for a directed donation?
A)8 weeks
B)2 weeks
C)48 hours
D)24 hours
Q2) Autologous donors may not donate if they:
A)have a positive test for syphilis.
B)are on antibiotics for an infection.
C)are taking aspirin.
D)are over 65 years old.
Q3) Before donation,the intended venipuncture site must be cleaned with:
A)PVP-iodine complex
B)Alcohol
C)10% acetone
D)Green soap
Q4) 65-year-old woman taking sleep medication at night
A)Acceptable donors
B)Temporarily deferred
C)Permanently deferred
D)Indefinite deferral
14
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Chapter 13: Testing of Donor Blood
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25 Verified Questions
25 Flashcards
Source URL: https://quizplus.com/quiz/38816
Sample Questions
Q1) If clinically significant red cell antibodies are found in donor units:
A)platelet and fresh frozen plasma cannot be transfused.
B)red blood cells can be used if the antibody interpretation is indicated on the label.
C)the unit must be discarded and the donor permanently deferred.
D)red blood cells must be washed before transfusion.
Q2) Cytomegalovirus-positive blood is dangerous for which of the following types of patients?
A)Premature infants
B)HIV-positive patients
C)Bone marrow recipients
D)Unborn infants of pregnant women who are seronegative
E)All of the above
Q3) The most sensitive test for HIV is:
A)enzyme-linked assays.
B)chemiluminescence.
C)Western blot.
D)nucleic acid.
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15
Chapter 14: Blood Component Preparation and Therapy
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29 Verified Questions
29 Flashcards
Source URL: https://quizplus.com/quiz/38817
Sample Questions
Q1) Following a platelet concentrate transfusion,a patient did not obtain the calculated corrected count increment that was expected.The possible reason(s)this did not occur is (are)the:
A)patient had a fever.
B)patient was actively bleeding.
C)patient has leukocyte antibodies.
D)All of the above are correct.
Q2) The temperature of a shipment of red blood cell units that was received from the local blood center was recorded as 8°<sup> </sup>C.The correct course of action is to:
A)place the units in inventory because the temperature is acceptable.
B)quarantine the units until approved by the supervisor.
C)send the units back to the blood center.
D)have the units tested for bacterial contamination before release.
Q3) The maximum acceptable storage temperature for frozen red blood cells is:
A)4° C.
B)-12° C.
C)-20° C.
D)-65° C.
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Chapter 15: Transfusion Therapy in Selected Patients
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25 Verified Questions
25 Flashcards
Source URL: https://quizplus.com/quiz/38818
Sample Questions
Q1) Reduce the risk of allergic reactions
A)Cryoprecipitated AHF
B)Fresh frozen plasma
C)Red blood cells
D)Platelets
E)Leuko-reduced blood components
F)Washed red blood cells
G)Albumin/plasma protein fraction
H)Factor concentrates
I)Plasma,cryoprecipitate reduced
J)Irradiated blood products
Q2) ABO-matched organ transplants are critical in all the following except:
A)bone marrow.
B)kidney.
C)heart.
D)liver.
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Chapter 16: Quality Assurance and Regulation of the Blood
Industry and Safety Issues in the Blood Bank
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38 Verified Questions
38 Flashcards
Source URL: https://quizplus.com/quiz/38819
Sample Questions
Q1) In a routine audit of a facilities blood collection area,the quality assurance department found that the blood bags being used on that particular day had expired.What is the appropriate course of action?
A)Initiate a root cause analysis and quarantine the blood collected in the expired bags.
B)Call the Food and Drug Administration to report the incident.
C)Change the expiration date on the bags to avoid legal issues.
D)Fire the donor room supervisor,and discard the blood collected in the expired bags.
Q2) All of the following are true regarding competency testing except:
A)it must be performed following training.
B)it must be performed on an annual basis.
C)it is required only if the technologist has no experience.
D)retraining is required if there is a failure in competency testing.
Q3) Plans that provide the framework for establishing quality assurance in an organization are:
A)current good manufacturing practices.
B)standard operating procedures.
C)change control plan.
D)continuous quality improvement plan.
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