Cell and Developmental Biology Test
Bank
Course Introduction
Cell and Developmental Biology explores the principles underlying the structure, function, and life cycle of cells, as well as the intricate processes that guide the development of multicellular organisms from a single cell to a complex body. This course covers topics such as cell structure and organization, cellular communication, gene regulation, stem cell biology, and the mechanisms of differentiation and morphogenesis. Students will also study model organisms to understand genetic, molecular, and cellular control of development, as well as contemporary research techniques used to investigate developmental processes. The course emphasizes the integration of cellular and developmental concepts to provide a foundation for understanding health, disease, and biotechnological applications.
Recommended Textbook
Human Embryology and Developmental Biology 5th Edition by Bruce M. Carlson
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18 Chapters
301 Verified Questions
301 Flashcards
Source URL: https://quizplus.com/study-set/1308
Page 2
Chapter 1: Getting Ready for Pregnancy
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10 Verified Questions
10 Flashcards
Source URL: https://quizplus.com/quiz/26053
Sample Questions
Q1) Functional maturation of spermatozoa occurs in the _________.
A)Epididymis
B)Ductus deferens
C)Prostate
D)Seminal vesicle
E)Upper vagina
Answer: A
Q2) Two systems-menstrual age and fertilization age-are used in signifying the age of embryos.To convert from menstrual age to fertilization age:
A)Add 1 week
B)Add 2 weeks
C)Subtract 1 week
D)Subtract 2 weeks
Answer: D
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3
Chapter 2: Transport of Gametes and Fertilization
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19 Verified Questions
19 Flashcards
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Sample Questions
Q1) The principal energy source for ejaculated spermatozoa is _____________.
A)Prostatic acid phosphatase
B)Internal glucose
C)Prostatic citric acid
D)Fructose in seminal vesicle fluid
E)Glycogen released from the vaginal epithelium
Answer: D
Q2) Of the barriers to sperm survival and transport within the female reproductive tract,low pH is most important in the ___________.
A)Upper uterine tube
B)Lower uterine tube
C)Uterine cavity
D)Cervix
E)Vagina
Answer: E
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Chapter 3: Cleavage and Implantation
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18 Verified Questions
18 Flashcards
Source URL: https://quizplus.com/quiz/26055
Sample Questions
Q1) Successful implantation depends on:
A)Dissolution of the zona pellucida
B)Production of syncytiotrophoblast
C)Cell adhesion
D)All of the above
E)None of the above
Answer: D
Q2) In the construction of a tetraparental mouse,what property of the cleaving embryo allows the formation of a single mouse from two separate embryos?
A)Induction
B)Bateson's rule
C)Regulation
D)Differentiation
E)Restriction
Answer: C
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Chapter 4: Molecular Basis for Embryonic Development
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9 Verified Questions
9 Flashcards
Source URL: https://quizplus.com/quiz/26056
Sample Questions
Q1) Which growth factor must be combined with cholesterol to be active?
A)Sonic hedgehog
B)Fibroblast growth factor-2
C)Transforming growth factor-
D)Bone morphogenetic protein-7
E)None of the above
Q2) -Catenin is an integral part of which signaling/signal transduction pathway?
A)Fibroblast growth factor/receptor tyrosine kinase
B)Wnt
C)Delta-Notch
D)Transforming growth factor/serine-threonine kinase
E)None of the above
Q3) Which Hox gene is expressed in the most anterior position in the embryonic body?
A)Hoxc-12
B)Hoxd-11
C)Hoxb-5
D)Hoxa-4
E)Hoxb-9
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Chapter 5: Formation of Germ Layers and Early Derivatives
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16 Verified Questions
16 Flashcards
Source URL: https://quizplus.com/quiz/26057
Sample Questions
Q1) Which cell adhesion molecule(s)rely(ies)heavily on Ca++ for its function?
A)N-CAM
B)E-cadherin
C)Integrin
D)All of the above
E)None of the above
Q2) The principal inductor in primary neural induction is the ____________.
A)Hypoblast
B)Primitive streak
C)Extraembryonic mesoderm
D)Notochordal process
E)Embryonic ectoderm
Q3) Which of the following tissues is not dependent on the proper functioning of the primitive streak?
A)Ectoderm
B)Notochord
C)Endoderm
D)Mesoderm
E)Amnion
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Chapter 6: Establishment of the Basic Embryonic Body Plan
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28 Verified Questions
28 Flashcards
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Sample Questions
Q1) Sonic hedgehog,secreted by the notochord,induces the formation of the
A)Prechordal plate
B)Neural crest
C)Floor plate
D)Roof plate
E)Dorsal root ganglia
Q2) A major embryonic signaling center,producing fibroblast growth factor-8 and Wnt-1 and inducing gradients of En-1 and En-2,is located at the ____________.
A)Hensen's node
B)Midbrain-hindbrain junction
C)Notochord
D)Prechordal plate
E)None of the above
Q3) The oropharyngeal membrane is composed of __________________.
A)Ectoderm + splanchnic mesoderm
B)Endoderm + splanchnic mesoderm
C)Ectoderm + endoderm
D)Ectoderm + splanchnic mesoderm + endoderm
E)Ectoderm + somatic mesoderm + endoderm
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Chapter 7: Placenta and Extraembryonic Membranes
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12 Verified Questions
12 Flashcards
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Sample Questions
Q1) Blood vessels associated with which structure enter the fetal component of the placenta?
A)Allantois
B)Decidua basalis
C)Amnion
D)Yolk sac
E)Decidua parietalis
Q2) Decidual cells can be found in the _______________.
A)Cytotrophoblast
B)Syncytiotrophoblast
C)Mesoderm of the placental villus
D)Endometrium
E)Body stalk
Q3) Which malformation can lead to polyhydramnios?
A)Meckel's diverticulum
B)Esophageal atresia
C)Persistent anal membrane
D)Omphalocele
E)Aganglionic megacolon
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Page 9
Chapter 8: Developmental Disorders: Causes, mechanisms, and Patterns
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11 Verified Questions
11 Flashcards
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Sample Questions
Q1) What percentage of congenital malformations is due to unknown causes?
A)5%
B)10%
C)25%
D)50%
E)75%
Q2) What was the earliest recognized cause of human birth defects?
A)Excess vitamin A
B)Rubella
C)Folic acid deficiency
D)Thalidomide
E)X-radiation
Q3) Administration of supplemental folic acid has markedly reduced the incidence of
A)Anencephaly
B)Down syndrome
C)Phocomelia
D)Cyclopia
E)Fetal alcohol syndrome
Page 10
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Chapter 9: Integumentary, skeletal, and Muscular Systems
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9 Verified Questions
9 Flashcards
Source URL: https://quizplus.com/quiz/26061
Sample Questions
Q1) How many nuclei would you expect to find in a myoblast?
A)1
B)2
C)4
D)8
E)None of the above
Q2) The skeletal musculature of the limb arises from the _________________.
A)Somatopleure of the lateral plate mesoderm
B)Neural crest
C)Splanchnopleure of the lateral plate mesoderm
D)Neural tube
E)Somites
Q3) In the development of the human vertebral column,the proatlas anlage becomes incorporated into which of the following?
A)Bodies of the atlas and axis
B)Basioccipital bone and the body of the atlas
C)Basioccipital bone and the dens of the axis
D)Body of the atlas and the dens of the axis
E)Body of the axis and the dens of the atlas
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Page 11
Chapter 10: Limb Development
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17 Verified Questions
17 Flashcards
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Sample Questions
Q1) The skeletal musculature of the limb arises from the _________________.
A)Somatopleure of the lateral plate mesoderm
B)Neural crest
C)Splanchnopleure of the lateral plate mesoderm
D)Neural tube
E)Somites
Q2) Which anomaly is due to the absence of programmed cell death?
A)Triphalangeal thumb
B)Phocomelia
C)Polydactyly
D)Syndactyly
E)Diplopodia
Q3) What is a principal function of the apical ectodermal ridge?
A)Stimulating outgrowth of the limb bud
B)Setting up the anteroposterior axis of the limb bud
C)Determining the organ-specific characteristics of the ectodermal appendages of the limb
D)Determining the pattern of neural ingrowth in the limb
E)Attracting the subcutaneous plexus of capillaries
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Page 12
Chapter 11: Nervous System
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15 Verified Questions
15 Flashcards
Source URL: https://quizplus.com/quiz/26063
Sample Questions
Q1) The floor plate of the spinal cord arises as the result of an induction by the
A)Notochord
B)Neural crest
C)Dorsal aorta
D)Dorsal part of somites
E)Overlying ectoderm
Q2) ?The alar plate is most closely associated with which function of the central nervous system?
A)Motor
B)Sympathetic
C)Sensory
D)Parasympathetic
E)None of the above
Q3) A molecule that repels the advance of a growth cone is called
A)Netrin
B)Acrosin
C)Cadherin
D)Semaphoring
E)Laminin
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Chapter 12: Neural Crest
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14 Verified Questions
14 Flashcards
Source URL: https://quizplus.com/quiz/26064
Sample Questions
Q1) Which of the following is a derivative of cranial,but not trunk,neural crest?
A)Sensory ganglia
B)Dermis
C)Melanocytes
D)Schwann cells
E)Autonomic ganglia
Q2) The coordinated pattern of migration of neural crest cells from rhombomere 2 to the first pharyngeal arch,rhombomere 4 into the second arch,and rhombomere 6 into the third arch is correlated with precise expression patterns of which of the Hox gene families?
A)Hox-1 (Hox A)
B)Hox-2 (Hox B)
C)Hox-3 (Hox C)
D)Hox-4 (Hox D)
Q3) Neural crest cells arise from the ______________.
A)Somite
B)Zone of polarizing activity
C)Neural tube
D)Splanchnic mesoderm
E)Yolk sac endoderm
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Chapter 13: Sense Organs
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17 Verified Questions
17 Flashcards
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Sample Questions
Q1) The otic placode is induced by the ______________.
A)Notochord
B)Second pharyngeal arch
C)Rhombencephalon
D)Primitive node
E)None of the above
Q2) Surface ectoderm is induced to become corneal epithelium by an inductive event originating in the _____________.
A)Optic cup
B)Chordamesoderm
C)Optic vesicle
D)Lens vesicle
E)Primitive neural retina
Q3) Coloboma results from _________________.
A)Nonclosure of the choroid fissure of the iris
B)Lack of induction by the lens
C)Lack of induction by the otic vesicle
D)Hypoplasia of the first pharyngeal arch
E)Incomplete migration of fourth pharyngeal pouch endoderm
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Chapter 14: Head and Neck
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33 Verified Questions
33 Flashcards
Source URL: https://quizplus.com/quiz/26066
Sample Questions
Q1) The philtrum of the lip is formed by the _______________.
A)Frontonasal prominence
B)Nasomedial processes
C)Nasolateral processes
D)Primary palate
E)Nasolacrimal groove
Q2) Which association is correct?
A)Pharyngeal arch 2 - Meckel's cartilage
B)Lesser horn of hyoid - styloid process
C)Masseter muscle - facial nerve
D)Posterior belly of the digastric muscle - pharyngeal arch 3
E)Glossopharyngeal nerve - stylopharyngeus muscle
Q3) Activity of which molecule steers the differentiation of pancreatic progenitor cells toward the exocrine pathway?
A)Neurogenin-3
B)Pax-6
C)Pax-4
D)Notch
E)None of the above
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Page 16
Chapter 15: Digestive and Respiratory Systems and Body
Cavities
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17 Verified Questions
17 Flashcards
Source URL: https://quizplus.com/quiz/26067
Sample Questions
Q1) A Meckel's diverticulum can contain ectopic _______________.
A)Gastric mucosa
B)Endometrium
C)Pancreatic tissue
D)All of the above
E)None of the above
Q2) Which of the following associations is correct?
A)Foregut - superior mesenteric artery
B)Midgut - jejunum
C)Midgut - celiac artery
D)Meckel's diverticulum - jejunum
E)Vermiform appendix - hindgut
Q3) Ectopic gastric mucosa can be found in the _____________.
A)Tongue
B)Colon
C)Biliary tract
D)Meckel's diverticulum
E)All of the above
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Chapter 16: Urogenital System
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29 Verified Questions
29 Flashcards
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Sample Questions
Q1) The urachus of the bladder is derived from the _______________.
A)Urogenital sinus
B)Fused müllerian ducts
C)Cloacal plate
D)Vitelline duct
E)Allantois
Q2) The ductus deferens is derived from the ________________.
A)Urogenital sinus
B)Mesonephric duct
C)Paramesonephric duct
D)Prostatic utricle
E)Genital folds
Q3) Exstrophy of the bladder is often associated with ______________.
A)Hypospadias
B)Epispadias
C)Bicornuate uterus
D)Rectovaginal fistula
E)Urachal fistula
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18
Chapter 17: Cardiovascular System
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19 Verified Questions
19 Flashcards
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Sample Questions
Q1) Massive collateral circulatory channels are opened up in individuals having which anomaly?
A)Patent ductus arteriosus
B)Preductal coarctation of the aorta
C)Double aortic arch
D)Right aortic arch
E)Postductal coarctation of the aorta
Q2) The ventral aortic root cephalic to the third aortic arch becomes the
A)External carotid artery
B)Stapedial artery
C)Ascending aorta
D)Internal carotid artery
E)Ductus arteriosus
Q3) The internal carotid artery arises from aortic arch ________.
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Chapter 18: Fetal Period and Birth
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8 Verified Questions
8 Flashcards
Source URL: https://quizplus.com/quiz/26070
Sample Questions
Q1) The most highly oxygenated blood in the fetus is found in the ______________.
A)Dorsal aorta
B)Umbilical arteries
C)Umbilical vein
D)Pulmonary arteries
E)Pulmonary vein
Q2) The ligamentum teres is the postnatal remains of the ______________.
A)Ductus arteriosus
B)Ductus venosus
C)Umbilical vein
D)Umbilical artery
E)Urachus
Q3) Insufficient production of ________________ is the most common cause of reduced survival in infants born 8 weeks prematurely.
A)Testosterone
B)Meconium
C)Urine
D)Insulin
E)Pulmonary surfactant
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Page 20