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Cardiopulmonary Science is an interdisciplinary course that explores the anatomy, physiology, and pathology of the heart and lungs, emphasizing their critical roles in human health. Students learn about the mechanisms of cardiac and respiratory function, diagnostic procedures, and current therapeutic interventions for related diseases. The course covers topics such as gas exchange, blood circulation, cardiovascular and pulmonary assessment, respiratory therapies, and the impact of lifestyle factors on cardiopulmonary health. Practical case studies and laboratory activities often complement theoretical knowledge, preparing students for clinical practice or further study in health professions.
Recommended Textbook
Integrated Cardiopulmonary Pharmacology 3rd Edition by Bruce J. Colbert
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15 Chapters
833 Verified Questions
833 Flashcards
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50 Verified Questions
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Sample Questions
Q1) Emetics are agents that are administered to induce vomiting in the event of poisoning.
A)True
B)False
Answer: True
Q2) The mechanisms responsible for metabolism of rifampin in the liver include: I.Drug oxidation.
II)Enzyme inhibition.
III)The cytochrome P-450 system.
A)I and II
B)I and III
C)II and III
D)I,II,and III
Answer: B
Q3) An interaction between two drugs that causes one drug to have no direct effect but increases the response of the other drug is referred to as the drug's potency.
A)True
B)False
Answer: False
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Sample Questions
Q1) A medication bag contains 0.03 liters.This is equal to how many milliliters?
A)3
B)30
C)300
D)3,000
Answer: B
Q2) How can you determine how much drug to administer if the drug available is not supplied in the prescribed amount?
Answer: You can use a proportion of the dose on hand related to the desired dose to set up an equation and solve for the correct amount.. Refer to Figure 2 4, which illustrates the steps in the equation.
Q3) How much active drug is in 3 ml of a 10% solution?
A)0.3 g
B)1 g
C)0.3 mg
D)1 mg
Answer: A
Q4) A liquid or solid that is dissolved in a solution is known as a ________________.
Answer: solute

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Sample Questions
Q1) Adrenergic receptors are found primarily in the smooth muscle of blood vessels,cardiac muscle,and the airways.
A)True
B)False
Answer: True
Q2) Sympathomimetic drugs are used for ________________ or
Answer: vasoconstriction/bronchodilation
Q3) Elimination of norepinephrine at the synaptic cleft is accomplished by which of the following mechanisms?
I)Reuptake
II)Metabolization by AChE
III)Metabolization by MAO
IV)Metabolization by COMT
A)I and II
B)I and III
C)I,II,and III
D)I,III,and IV
Answer: D
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Sample Questions
Q1) While treating a 3-year-old patient at a hospital clinic,you are asked to select an aerosol device for bronchodilator therapy at home.The most appropriate device for this patient is:
A)A bulb nebulizer.
B)A dry powder inhaler.
C)An MDI with a spacer.
D)An MDI.
Q2) A DPI contains liquid aerosol particles that are released when the device is activated.
A)True
B)False
Q3) Aerosol deposition is defined as:
A)Particles falling out of suspension.
B)The depth to which the aerosol particles reach within the lungs.
C)The velocity at which the aerosol particles travel.
D)The ability of an aerosol particle to stay in suspension.
Q4) The inhalation route of drug administration delivers a precise dose of medication to the lungs with each aerosol treatment.
A)True
B)False
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Sample Questions
Q1) Methylxanthines are believed to cause bronchodilation by which of the following mechanisms?
A)Inhibiting phosphodiesterase
B)Decreasing cyclic AMP
C)Increasing cyclic GMP
D)Inhibiting COMP
Q2) In order to quantify airway obstruction and posttreatment improvement the respiratory therapist can measure a patient's ____________ or ____________.
Q3) Parasympatholytic bronchodilators can be described as: I.Drugs that stimulate the parasympathetic system
II)Anticholinergic drugs
III)Drugs that block acetylcholine
A)I and II
B)II and III
C)I,II,and III
D)II only
Q4) Selective beta<sub>2</sub>-agonists that are used for continuous nebulization during severe acute episodes of bronchospasm include ____________ and ____________.
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Q1) Of the following,which is responsible for producing most of the mucus found in the airways?
A)Serous cells
B)Bronchial glands
C)Goblet cells
D)Clara cells
Q2) When a patient has a dry,nonproductive cough,a ________________ saline solution can be administered to stimulate a cough and produce more mucus.
Q3) Synthetic surfactants can be described as which of the following?
I)Exogenous
II)Containing proteins SP-B and SP-C
III)Free of infection and foreign proteins
A)I and II
B)II and III
C)I and III
D)I,II,and III
Q4) Compare and contrast the two types of exogenous surfactants that are currently available.
Q5) The saline solution that is considered to be an expectorant is
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Q1) Mast cells containing histamine are located in nasal passages but are not found in the airways.
A)True
B)False
Q2) Histamine smooth muscle contraction is controlled by ________________ receptors.
Q3) Nasal decongestants are ________________ drugs and cause vasoconstriction that reduces blood flow and swelling of the nasal passages.
Q4) Allergic asthma is also referred to as "extrinsic asthma."
A)True
B)False
Q5) The breakdown of the phospholipid membrane during an inflammatory response produces ________________ acid.
Q6) The antihistamine effect of Allegra is accomplished by which of the following mechanisms?
A)Blocking the action of histamine at histamine 1 receptors
B)Stabilizing the mast cell membrane and preventing release of histamine
C)Inhibiting the effect of histamine by blocking lipoxygenase pathways
Page 9
D)Inhibiting cytokine release from nasal epithelial cells
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Sample Questions
Q1) An antifungal used to treat candida albicans is:
A)Azole.
B)Diflucan.
C)Monistat.
D)Nystatin.
Q2) What are the signs and symptoms of infection in the respiratory system?
Q3) ________________,________________,and ________________ are methods used to determine the susceptibility of a microorganism to antibiotic therapy.
Q4) Daptomycin can be administered to treat all of the following microorganisms except:
A)MRSA bloodstream infections.
B)Pneumonias.
C)Vancomycin-resistant enterococci.
D)Gram-positive organisms.
Q5) A patient who is prescribed cephalexin will not have to take the medication as often as he or she would have to take amoxicillin.
A)True
B)False
Q6) Penicillins are classified as ________________.
Page 10
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Q1) The ________________ valve separates the right atrium and ventricle,and the ________________ valve separates the left atrium and ventricle.
Q2) Atrial depolarization is represented on an ECG tracing as a ________________.
Q3) The time in which cardiac cells cannot be excited after electrical stimulation is called the _________________________.
Q4) Which of the following is the agent of choice for relief of anginal pain?
A)Nitroprusside
B)Dopamine
C)Levophed
D)Nitroglycerin
Q5) Drugs that affect the force of contraction are referred to as _______________.
Q6) The QRS complex represents repolarization of the ventricles.
A)True
B)False
Q7) ACE inhibitors are used to reduce the work of the heart by:
A)Inducing vasodilation.
B)Correcting an electrolyte imbalance.
C)Improving cardiac contractility.
D)Slowing the heart rate.
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Q1) A patient that has a blood pressure of 138/85 mmHg and is asymptomatic should receive which of the following initial treatments?
A)ACE inhibitors
B)Diuretic therapy
C)Beta blockers
D)Lifestyle modification
Q2) _______________ is an anticoagulant that is administered orally.
Q3) What is the purpose of using heparin in IV lines or central venous and arterial catheters,and what might occur without heparinized solutions at these sites?
Q4) Which of the following is a side effect associated with giving ACE inhibitors to patients with decreased renal function?
A)Peripheral edema
B)Hyperkalemia
C)Dizziness
D)Reflex tachycardia
Q5) Aspirin,when used to disrupt the clotting mechanism,is classified as ________________ drug.
Q6) Explain the difference between anticoagulants,antiplatelets,and thrombolytics.
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Q1) Vicodin,an effective analgesic,combines acetaminophen with which of the following?
A)Codeine
B)Hydrocodone
C)Morphine
D)Fentanyl
Q2) ________________ can be categorized as sedatives,hypnotics,and anxiolytics.
Q3) Why is Versed used during major and minor surgical procedures?
Q4) Patients most likely to become addicted to the euphoric effects of opioids are those being treated:
A)During labor and delivery.
B)For malignant pain.
C)For pulmonary edema.
D)For myocardial infarction.
Q5) Drugs that reduce CNS arousal are classified as ________________.
Q6) ________________ anesthetics make a specific region of the body insensitive to pain without loss of consciousness.
Page 13
Q7) A local anesthetic works by binding to a membrane site and preventing the neurons from ________________.
Q8) Explain the difference between nondepolarizing and depolarizing NMBAs.
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Q1) What does the term "affinity" mean in relation to hemoglobin and oxygen?
Q2) The FIO<sub>2 </sub>delivered in _______________ oxygen systems is affected by the patient's rate and depth of breathing.
Q3) Sickle cell anemia is a condition that leads to hypoxemic hypoxia.
A)True
B)False
Q4) Left-to-right shunt occurs when blood leaves the right heart and bypasses a portion of the pulmonary circulation.
A)True
B)False
Q5) A patient with a tracheostomy is weaned successfully from the ventilator and is now breathing spontaneously but needs supplemental oxygen.His arterial blood gases were within normal limits,with an FIO<sub>2</sub> of 40% on the ventilator.Which of the following devices would you recommend?
A)An air-entrainment mask
B)A large-volume nebulizer with tracheostomy collar
C)A simple mask
D)A large-volume nebulizer with face tent
Q6) PaO<sub>2</sub> represents the measure of oxygen that is
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Q1) ________________ is a reversible obstructive disease,and ________________ is progressive and not fully reversible.
Q2) Which of the following patients is likely to present with a hyperinflated barrel chest?
I.A patient with asthma
II.A patient with chronic bronchitis
III.A patient with emphysema
A)I and II
B)II and III
C)I and III
D)I,II,and III
Q3) Of the following medications,which would you recommend during an asthmatic episode to provide the quickest relief?
A)Aminophylline
B)Epinephrine
C)Ipratropium bromide
D)Levalbuterol
Q4) Describe the meanings of the terms "pink puffer" and "blue bloater."
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Q5) Inhaled corticosteroids should always be administered with a
Q6) Leukotriene inhibitors have no established use in patients with
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Sample Questions
Q1) The preferred antibiotic therapy against H.influenzae type B for the treatment of epiglottitis includes all except which of the following?
A)Clindamycin
B)Cefuroxime
C)Cefotaxime
D)Ceftriaxone
Q2) Treatment for tuberculosis consists of combination drug therapy for 2 consecutive months.
A)True
B)False
Q3) Patients who are allergic to penicillin should not be prescribed ________________ antibiotics.
Q4) Pneumonias that are acquired due to inhalation of contaminated aerosols are most often contaminated with all except which of the following?
A)Legionella spiritensis
B)Aspergillus spiritensis
C)Respiratory syncytial virus
D)Influenza virus
Q5) What are the causative agents for croup and how is it treated?
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Sample Questions
Q1) Norepinephrine is used for severe hypotension and low total peripheral vascular resistance refractory to other sympathomimetics.
A)True
B)False
Q2) A patient is brought to the emergency room in full cardiac arrest.The paramedics have not been able to establish intravenous access for administration of resuscitation drugs.Which of the following should be considered?
I.Administering drugs via the endotracheal tube
II.Having the nurse insert a gastric tube
III.Using an intraosseous route
A)I and II
B)I and III
C)II and III
D)I,II,and III
Q3) To treat a patient who is in ventricular fibrillation,a health care team should follow the ________________ algorithm.
Q4) Why is it important for a respiratory therapist to know whether sodium bicarbonate is being administered during resuscitation?
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