Blood Banking and Transfusion Medicine
Final Exam Questions
Course Introduction
This course covers the principles and practices of blood banking and transfusion medicine, focusing on the collection, processing, storage, and compatibility testing of blood and its components. Students will explore blood group systems, immunohematology, donor screening, and the management of transfusion reactions and infectious risks. Emphasis is placed on laboratory techniques, quality assurance, regulatory standards, and the clinical application of transfusion therapy in various medical contexts. Through a combination of theoretical knowledge and practical exercises, students gain the competencies necessary for safe and effective transfusion practices in healthcare settings.
Recommended Textbook
Basic and Applied Concepts of Blood Banking and Transfusion Practices 4th Edition by Paula R.
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16 Chapters
461 Verified Questions
461 Flashcards
Source URL: https://quizplus.com/study-set/896
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Chapter 1: Quality Assurance and Regulation of the Blood
Industry and Safety Issues in the Blood Bank
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38 Verified Questions
38 Flashcards
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Sample Questions
Q1) Proficiency test
A)The CAP survey is an example
B)Systematic evaluations to determine whether procedures are being followed
C)Testing to determine the accuracy and precision of reagents and equipment
D)Process of standardizing an instrument against a known value
E)Removal of products from the market that might compromise the safety of the recipient
F)Degree to which a measurement represents the true value
G)Establishing that a specific process produces an expected result
H)Evaluation of an employee's ability to perform a specific skill
I)Investigation and identification of the factors that contributed to an error
J)Maximizes the duration of equipment and increases the reliability of the equipment
K)System to plan and implement changes to prevent problems
Answer: A
Q2) All accidents,even minor ones,must be reported to a supervisor.
A)True
B)False
Answer: True
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Chapter 2: Immunology: Basic Principles and Applications
in the Blood Bank
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39 Verified Questions
39 Flashcards
Source URL: https://quizplus.com/quiz/17671
Sample Questions
Q1) Select the substance that regulates the activity of other cells by binding to specific receptors.
A) Cytokines
B) Complement
C) Immunoglobulins
D) Anaphylatoxin
Answer: A
Q2) Which of the following is responsible for the activation of the classic pathway of complement?
A) Bacteria
B) Foreign proteins
C) Virus
D) Antibody bound to antigen
Answer: D
Q3) What immunoglobulin class is capable of crossing the placenta?
A) IgM
B) IgA
C) IgE
D) IgG
Answer: D
Page 4
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Chapter 3: Blood Banking Reagents: Overview and Applications
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34 Verified Questions
34 Flashcards
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Sample Questions
Q1) Reagent used to determine the ABO antigenic composition of a patient's red cells
A)Panel cells
B)Screening cells
C)A1 and B cells
D)ABO antisera
E)Lectins
Answer: D
Q2) Reagent antibodies prepared from human sources are:
A) unsafe.
B) too low in potency to be effective.
C) polyclonal in specificity.
D) preferred because of their lower cost.
Answer: C
Q3) Which red cells are used to screen for antibodies in donor samples?
A) Screening cells (two vials)
B) Pooled screening cells
C) Panel cells
D) Screening cells (three vials)
Answer: B
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Chapter 4: Genetic Principles in Blood Banking
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32 Verified Questions
32 Flashcards
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Sample Questions
Q1) When does crossing over occur?
A) Meiosis
B) Mitosis
C) Somatic cell division
D) Zygote formation
Q2) What is an advantage of Nucleic Acid Testing (NAT)for viral marker testing?
A) Quicker to perform than most other tests
B) More cost effective than traditional test methods
C) A small amount of DNA or RNA can be detected
D) No problem with cross-contamination of samples
Q3) In a random population,16% of the population is homozygous for a particular trait.What percentage of the same population is heterozygous for that particular trait?
A) 32%
B) 64%
C) 48%
D) 84%
Q4) Parents,who both phenotype as group A,cannot have a group O child.
A)True
B)False
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Chapter 5: ABO and H Blood Group Systems and Secretor
Status
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25 Verified Questions
25 Flashcards
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Sample Questions
Q1) Predict the agglutination reaction of red cells from a Bombay phenotype when combined with anti-H lectin.
A) Strong 4+
B) Mixed field
C) Weak 1+
D) Negative
Q2) Group O
A)D-galactose
B)L-fucose
C)N-acetylgalactosamine
D)None of the above
Q3) To distinguish between an A and A blood type,which reagent is used?
A) Ulex europeaus lectin
B) Anti-A,B
C) Monoclonal anti-A
D) Dolichos biflorus lectin
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Chapter 6: Rh Blood Group System
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) DCe
A)R<sup> </sup>r
B)R<sup> </sup>R<sup> </sup>
C)R<sup> </sup>R<sup> </sup>
D)rr
Q2) How is it genetically possible for a child to phenotype as D-negative?
A) Both parents are heterozygous D-positive.
B) Both parents are homozygous D-positive.
C) Mom is homozygous D-positive, and Dad is heterozygous D-positive.
D) The sibling is D-positive.
Q3) ce
A)R<sup> </sup>r
B)R<sup> </sup>R<sup> </sup>
C)R<sup> </sup>R<sup> </sup>
D)rr
Q4) R<sup> </sup>
A)Ce
B)CE
C)DCE
D)Dce
Page 8
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Chapter 7: Other Red Cell Blood Group Systems, Human
Leukocyte Antigens, and Platelet Antigens
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) The mixed lymphocyte culture (MLC)is a procedure that has been used in HLA testing to determine:
A) class I HLA antigen determination.
B) class II HLA antigen determination.
C) HLA antibody identification.
D) compatibility testing for tissue typing.
E) B and D.
Q2) Which of the following facts is not a characteristic of Kell system antibodies?
A) Usually clinically significant IgG antibodies
B) Best detected in indirect antiglobulin test phases
C) Lose reactivity with proteolytic enzyme reagents
D) Do not bind complement proteins
Q3) HLA matching between the donor and recipient is important for progenitor cell transplantation to avoid:
A) graft versus host disease (GVHD).
B) graft rejection.
C) transfusion reactions.
D) A and B.
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Chapter 8: Antibody Detection and Identification
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) Select the example of a cold alloantibody.
A) Anti-M.
B) Anti-I.
C) Anti-Lu<sup>b</sup>.
D) Anti-k.
Q2) A patient's serum reacted weakly with all panel cells tested at the antiglobulin phase using LISS and were not enhanced using PEG.The autocontrol was negative.Ficin-treated panel cells were nonreactive.What is the most likely specificity of the antibody?
A) Anti-I
B) Anti-U
C) Anti-Ch
D) Anti-Js<sup>b</sup>
Q3) In an antibody identification panel,only one red cell was negative at the antihuman globulin phase.On ruling out and matching the pattern,an anti-k was identified.What further testing is necessary to confirm the antibody?
A) Two more k-negative cells should be tested.
B) Two more K-negative cells should be tested.
C) Treat the panel cells with enzymes and perform the panel again.
D) Perform an adsorption using "k"-positive cells.
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Page 10
Chapter 9: Compatibility Testing
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26 Verified Questions
26 Flashcards
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Sample Questions
Q1) What can be done to increase the sensitivity of the antibody screen in a compatibility test?
A) Extend the incubation time.
B) Increase the serum-to-cell ratio.
C) Use an enhancement such as polyethylene glycol.
D) All of the above are correct.
Q2) The use of the electronic (computer)crossmatch is restricted to recipients who: A) are group O.
B) do not have a clinically significant antibody.
C) have had successful transfusions in the past.
D) have transfusion history that has been documented in the computer.
Q3) If an emergency exists and there is not enough time to perform a crossmatch for red cells,what is the correct procedure?
A) Release group O, D-negative whole blood.
B) Release group O, D-negative RBC units.
C) Release group AB fresh frozen plasma until the blood type is performed.
D) Release ABO-compatible blood based on the patient's prior record in the computer.
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Chapter 10: Blood Bank Automation for Transfusion Services
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10 Verified Questions
10 Flashcards
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Sample Questions
Q1) The PROVUE,TANGO,and NEO have the ability to perform all of the following tests except:
A) ABO/D typing.
B) antibody ID panels.
C) direct antiglobulin test.
D) acid elution.
Q2) Random access is an important feature in selecting an automated instrument for testing in the transfusion service.What is random access?
A) Ability of multiple users to sign into the system
B) The recognition of various types of barcodes
C) The need for minimal maintenance procedures
D) The ability to accommodate STAT testing
Q3) Which of the following instruments performs assays using gel technology?
A) ECHO
B) PROVUE
C) NEO
D) TANGO
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12
Chapter 11: Adverse Complications of Transfusions
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) A 44-year-old woman has a hemoglobin level of 6.1 g/dL.White blood cell and platelet counts are within normal levels.The patient is group O D-negative with a negative antibody screen.Crossmatches are compatible.However,15 minutes after the start of the first transfusion,she experiences erythema and hives.What type of transfusion reaction is occurring?
A) Urticarial
B) Febrile nonhemolytic
C) Delayed hemolytic
D) Acute hemolytic
Q2) What component is indicated for patients who receive directed donations from immediate family members to prevent graft-versus-host transfusion reactions?
A) Irradiated red blood cells
B) Packed red blood cells
C) Washed red blood cells
D) Cytomegalovirus-negative red blood cells
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Chapter 12: Hemolytic Disease of the Fetus and Newborn
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30 Flashcards
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Sample Questions
Q1) A weakly reactive anti-D was detected in a sample from a D-negative mother one day following delivery of a D-negative baby.Based on these results,what is the next step?
A) Titer the anti-D
B) Perform a rosette test
C) Review records for prenatal RhIG administration
D) Administer RhIG
Q2) All of the following are goals of an exchange transfusion except to:
A) correct anemia.
B) remove high levels of unconjugated bilirubin.
C) remove high levels of maternal antibody.
D) restore the platelet count.
Q3) Amniotic fluid analysis showed a marked increase into zone III of the Liley graph.Lecithin-sphingomyelin ratios indicated that the fetal lungs were not mature.Select the most appropriate decision regarding medical intervention.
A) No immediate need for intervention
B) An intrauterine transfusion
C) Delivery by cesarean section
D) None of the above
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14
Chapter 13: Donor Selection and Phlebotomy
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) A male donor has a reactive nucleic acid test for hepatitis C.What kind of deferral is assigned to this donor?
A) Indefinite
B) Permanent
C) Temporary
D) None of the above
Q2) Before donation,the intended venipuncture site must be cleaned with:
A) PVP-iodine complex.
B) alcohol.
C) 10% acetone.
D) green soap.
Q3) 22-year-old man who returned from Iraq 3 months ago and was vaccinated for tetanus and yellow fever before being deployed
A)Acceptable donors
B)Temporarily deferred
C)Permanently deferred
D)Indefinite deferral
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Chapter 14: Testing of Donor Blood
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23 Verified Questions
23 Flashcards
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Sample Questions
Q1) What is the significance of a positive RPR test for syphilis?
A) Antibodies to Treponema pallidum are present
B) Past or present venereal disease infection
C) Possibility of an infection with Treponema pallidum
D) Antigens associated with venereal disease are present
Q2) Which of the following patients should not receive cytomegalovirus (CMV)-positive blood?
A) Premature infants
B) HIV-positive patients
C) Bone marrow recipients
D) Unborn infants of pregnant women who are seronegative
E) All of the above
Q3) Which hepatitis virus is transmitted similar to hepatitis A?
A) Hepatitis E virus
B) Hepatitis B virus
C) Hepatitis C virus
D) Hepatitis D virus
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Chapter 15: Blood Component Preparation and Therapy
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29 Verified Questions
29 Flashcards
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Sample Questions
Q1) AS-3 or AS-2
A)21 days
B)35 days
C)42 days
D)10 years
E)28 days
F)24 hours
G)48 hours
H)72 hours
Q2) Frozen
A)21 days
B)35 days
C)42 days
D)10 years
E)28 days
F)24 hours
G)48 hours
H)72 hours
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Chapter 16: Transfusion Therapy in Selected Patients
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25 Verified Questions
25 Flashcards
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Sample Questions
Q1) Bleeding due to thrombocytopenia
A)Cryoprecipitated AHF
B)Fresh frozen plasma
C)Red blood cells
D)Platelets
E)Leukoreduced blood components
F)Washed red blood cells
G)Albumin/plasma protein fraction
H)Factor concentrates
I)Plasma, cryoprecipitate reduced
J)Irradiated blood products
Q2) Which of the following contributes to the high blood usage in a liver transplant surgery?
A) The liver is a very large organ.
B) It is difficult to find close human leukocyte antigen matches for liver transplants.
C) Platelets are stored in the liver.
D) The liver produces the vitamin K-dependent coagulation factors.
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