Biomedical Science
Pre-Test Questions
Course Introduction
Biomedical Science is an interdisciplinary field that combines principles of biology, chemistry, and medicine to explore the mechanisms underlying human health and disease. This course examines the structure and function of the human body at the molecular, cellular, and systemic levels, covering topics such as genetics, microbiology, immunology, pathology, and pharmacology. Students will gain an understanding of the scientific foundations behind diagnostic techniques, therapeutic strategies, and medical research, preparing them to contribute to advancements in healthcare, laboratory analysis, and biomedical innovation.
Recommended Textbook
Basic and Applied Concepts of Blood Banking and Transfusion Practices 4th Edition by Paula R.
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16 Chapters
461 Verified Questions
461 Flashcards
Source URL: https://quizplus.com/study-set/896 Page 2
Chapter 1: Quality Assurance and Regulation of the Blood
Industry and Safety Issues in the Blood Bank
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38 Verified Questions
38 Flashcards
Source URL: https://quizplus.com/quiz/17670
Sample Questions
Q1) Plans that provide the framework for establishing quality assurance in an organization are:
A) current good manufacturing practices.
B) standard operating procedures.
C) change control plan.
D) continuous quality improvement plan.
Answer: D
Q2) In safety training,employees must become familiar with all of the following except:
A) tasks that have an infectious risk.
B) limits of protective clothing and equipment.
C) the appropriate action to take if exposure occurs.
D) how to perform cardiopulmonary resuscitation on a donor or other employee.
Answer: D
Q3) Personal protective equipment includes:
A) safety glasses.
B) splash barriers.
C) masks.
D) All of the above
Answer: D
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Chapter 2: Immunology: Basic Principles and Applications
in the Blood Bank
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39 Verified Questions
39 Flashcards
Source URL: https://quizplus.com/quiz/17671
Sample Questions
Q1) Which of the following components in the complement cascade mediates the lysis of the target cells?
A) C1qrs
B) C4a, C3a, and C5a
C) C5 to C9
D) C3a and C3b
Answer: C
Q2) Associated with allergic reactions and mast cell activation
A)IgA
B)IgM
C)IgG
D)IgE
Answer: D
Q3) Has the highest number of antigen binding sites
A)IgA
B)IgM
C)IgG
D)IgE
Answer: B
Page 4
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Chapter 3: Blood Banking Reagents: Overview and Applications
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34 Verified Questions
34 Flashcards
Source URL: https://quizplus.com/quiz/17672
Sample Questions
Q1) What method displays a positive reaction as a compact red cell button?
A) Gel test
B) Microtiter plate
C) Solid-phase red cell adherence
D) Molecular testing
Answer: B
Q2) How would you interpret the results if both the anti-D reagent and the Rh control were 2+ agglutination reactions?
A) D-positive
B) D-negative
C) Unable to determine without further testing
D) Depends on whether the sample was from a patient or a blood donor
Answer: C
Q3) Reagent derived from plants used to distinguish group A from group A red cells
A)Panel cells
B)Screening cells
C)A1 and B cells
D)ABO antisera
E)Lectins
Answer: E
Page 5
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Chapter 4: Genetic Principles in Blood Banking
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32 Verified Questions
32 Flashcards
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Sample Questions
Q1) Equal expression of two different inherited genes as in most blood group systems
A)Haplotypes
B)Recessive
C)Amorphic genes
D)Codominant genes
E)Polymorphic
Q2) In a random population,16% of the population is homozygous for a particular trait.What percentage of the same population is heterozygous for that particular trait?
A) 32%
B) 64%
C) 48%
D) 84%
Q3) Parents,who both phenotype as group A,cannot have a group O child.
A)True
B)False
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6
Chapter 5: ABO and H Blood Group Systems and Secretor
Status
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25 Verified Questions
25 Flashcards
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Sample Questions
Q1) A recipient with group A phenotype requires a transfusion of 2 units of frozen plasma.Which of the following types are appropriate to select for transfusion?
A) AB and B
B) B and A
C) O and A
D) AB and A
Q2) Which ABO phenotype selection contains the most H antigen and the least H antigen,respectively,on the red cell's surface?
A) O, A<sub>1</sub>B
B) A<sub>2</sub>, A<sub>1</sub>B
C) B, A
D) A<sub>1</sub>B, O
Q3) What substances are found in the saliva of a group A person who also inherited the secretor gene?
A) A, H
B) H
C) A, Se
D) A, B, H
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Chapter 6: Rh Blood Group System
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) All of the following can cause the D antigen expression to be weaker except:
A) inheriting the G gene.
B) inheriting the C antigen in trans to the D antigen.
C) an RHD gene that is genetically weaker.
D) partial D expression.
Q2) Red cells that phenotype as D-negative indicate that:
A) they inherited two D genes.
B) there is no genetic material inherited from the RHD gene from both parents.
C) a suppressor gene was inherited that is turning off the D gene expression.
D) reagents currently in use are not detecting the D antigen.
Q3) ce
A)R<sup> </sup>r
B)R<sup> </sup>R<sup> </sup>
C)R<sup> </sup>R<sup> </sup>
D)rr
Q4) The LW antigen expression is typically stronger on _____________ red cells.
A) D-positive
B) D-negative
C) Rh null
D) D-variant
Page 8
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Chapter 7: Other Red Cell Blood Group Systems, Human
Leukocyte Antigens, and Platelet Antigens
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) System associated with McLeod phenotype
A)Cartwright
B)MNSs
C)Kidd
D)Vel
E)Xg<sup>a</sup>
F)Sd<sup>a</sup> antigen
G)Chido/Rodgers
H)Kell
I)Duffy
Q2) Why have Lewis system antibodies not been implicated in hemolytic disease of the fetus and newborn?
A) The antigens are not fully developed at birth.
B) Lewis system antibodies do not cross the placenta.
C) The antibodies are not clinically significant.
D) All of the above are correct.
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Chapter 8: Antibody Detection and Identification
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) In the process of identifying an antibody,the technologist observed 2+ reactions with 3 of the 10 cells in a panel at the immediate-spin phase.These reactions disappeared following incubation at 37° C and the antihuman globulin phase of testing.What is the most likely responsible antibody?
A) Anti-E
B) Anti-D
C) Anti-I
D) Anti-Le<sup>a</sup>
Q2) Select the antibody that is not produced against a low-incidence antigen.
A) Anti-Vel
B) Anti-C<sup>w</sup>
C) Anti-V
D) Anti-Lu<sup>a</sup>
Q3) All screening cells positive 1+ at IS,DAT positive,C3 1+
A)Alloantibody, IgG
B)Alloantibody, IgM
C)Autoantibody, IgM
D)Autoantibody or transfusion reaction, IgG
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Chapter 9: Compatibility Testing
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26 Verified Questions
26 Flashcards
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Sample Questions
Q1) Given the following red cell antigen frequencies:
K 10%
E 30%
K 90%
P 80%
Which of the following red cell alloantibodies would be responsible for incompatible crossmatches with one 1 of 10 random donor units?
A) Anti-K
B) Anti-E
C) Anti-k
D) Anti-P
Q2) A 29-year-old female was admitted to the emergency room with severe bleeding.The blood type was group AB,D-negative.Six units of RBCs are ordered STAT.Of the following types available in the blood bank,which would be the most preferable for crossmatch?
A) AB, D positive
B) A, D negative
C) A, D positive
D) O, D negative
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11
Chapter 10: Blood Bank Automation for Transfusion Services
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10 Verified Questions
10 Flashcards
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Sample Questions
Q1) LIS interfaces are an important component in automation because of its potential in:
A) recognizing errors in sample ID.
B) flagging discrepancies with previous test results.
C) providing a mechanism for the electronic crossmatch.
D) All of the above
Q2) Random access is an important feature in selecting an automated instrument for testing in the transfusion service.What is random access?
A) Ability of multiple users to sign into the system
B) The recognition of various types of barcodes
C) The need for minimal maintenance procedures
D) The ability to accommodate STAT testing
Q3) The TANGO,PROVUE,and NEO all use one of the following reagents or components in the indirect antiglobulin test.
A) Washing mechanism
B) Centrifuge
C) Indicator cells
D) Antihuman globulin
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Chapter 11: Adverse Complications of Transfusions
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) In a delayed hemolytic transfusion reaction,what is a typical DAT result?
A) Negative
B) Positive due to C3
C) Mixed field positive
D) Very strongly positive
Q2) What component is indicated for patients who receive directed donations from immediate family members to prevent graft-versus-host transfusion reactions?
A) Irradiated red blood cells
B) Packed red blood cells
C) Washed red blood cells
D) Cytomegalovirus-negative red blood cells
Q3) Which of the following transfusion reactions can be linked to the administration of whole blood to a patient with cardiac insufficiency?
A) Delayed hemolytic reaction
B) Transfusion-related acute lung injury (TRALI)
C) Circulatory overload (TACO)
D) Febrile nonhemolytic reaction
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13
Chapter 12: Hemolytic Disease of the Fetus and Newborn
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) Select the most common antibody specificity associated with hemolytic disease of the fetus and newborn.
A) Anti-A,B
B) Anti-C
C) Anti-D
D) Anti-K
Q2) The rosette test will detect a fetomaternal hemorrhage as small as:
A) 5 mL
B) 10 mL
C) 15 mL
D) 20 mL
Q3) To prevent graft-versus-host disease,red blood cells prepared for intrauterine transfusions should be:
A) frozen and deglycerolized.
B) saline washed.
C) ABO and D-compatible with the mother.
D) irradiated.
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Chapter 13: Donor Selection and Phlebotomy
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30 Verified Questions
30 Flashcards
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Sample Questions
Q1) 50-year-old woman on vacation in the United States who currently lives in England
A)Acceptable donors
B)Temporarily deferred
C)Permanently deferred
D)Indefinite deferral
Q2) Allogeneic whole blood donors may donate every __________ days.
A) 24
B) 36
C) 56
D) 72
Q3) Which of the following is not a cause for temporary deferment of a whole blood donor?
A) Aspirin ingestion 12 hours previously
B) Hepatitis B immunoglobulin taken 4 weeks previously
C) Oral polio vaccine taken 1 week previously
D) Rubella injection 1 week previously
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Chapter 14: Testing of Donor Blood
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23 Verified Questions
23 Flashcards
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Sample Questions
Q1) If a donor is positive for hepatitis C virus by nucleic acid testing,why is the process of "look-back" initiated?
A) To quarantine units in the blood center that may exist from prior donations from the inventory
B) To notify recipients who may have previously received blood from this donor
C) To locate and quarantine units sent to transfusion facilities from this donor in the past
D) All of the above
Q2) Some donor centers have implemented the practice of diverting the first few milliliters of blood collected into a pouch attached to the collection bag.What is the purpose of this procedure?
A) Reduce leukocyte contamination
B) Prepare pedipacks for neonates
C) Avoid bacterial contamination
D) Collect blood for viral testing
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Chapter 15: Blood Component Preparation and Therapy
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29 Verified Questions
29 Flashcards
Source URL: https://quizplus.com/quiz/17684
Sample Questions
Q1) What is the correct storage temperature and time limit for pooled platelets?
A) 20° to 24° C, 5 days
B) 1° to 6° C, 7 days
C) 1° to 10° C, 24 hours
D) 20° to 24° C, 4 hours
Q2) The temperature of a RBC unit shipment from the local blood center was recorded as 8° C upon arrival at the hospital.What is the correct course of action?
A) Place the units in inventory because the temperature is acceptable.
B) Quarantine the units until approved by the supervisor.
C) Send the units back to the blood center.
D) Have the units tested for bacterial contamination before release.
Q3) Liquid plasma from whole blood
A)20° to 24° C, 4 hours
B)1° to 6° C, 24 hours
C)20° to 24° C, 6 hours
D)< -18° C, 1 year from collection
E)1° to 6° C, up to 5 days
F)< -65° C, 7 years
G)20° to 24° C, 48 hours
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Page 17
Chapter 16: Transfusion Therapy in Selected Patients
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25 Verified Questions
25 Flashcards
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Sample Questions
Q1) Deficiency of factor XIII and von Willebrand factor
A)Cryoprecipitated AHF
B)Fresh frozen plasma
C)Red blood cells
D)Platelets
E)Leukoreduced blood components
F)Washed red blood cells
G)Albumin/plasma protein fraction
H)Factor concentrates
I)Plasma, cryoprecipitate reduced
J)Irradiated blood products
Q2) Which of the following is used in the treatment of hemophilia A?
A) Factor VIII concentrate
B) Factor XIII concentrate
C) Platelets
D) Fresh frozen plasma
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