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COVID-19 Vaccine Logistics Handbook - Spring 2021

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COVID-19 VACCINE LOGISTICS HANDBOOK SPRING 2021


INTRODUCTION FROM HELLMANN EDITORIAL Editor: Sean Galea-Pace sean.galea-pace@outlookpublishing.com Editor: Marcus Kääpä marcus.kaapa@outlookpublishing.com PRODUCTION Art Director: Stephen Giles steve.giles@outlookpublishing.com Senior Designer: Devon Collins devon.collins@outlookpublishing.com Junior Designer: Matt Loudwell matt.loudwell@outlookpublishing.com BUSINESS Managing Director: Ben Weaver ben.weaver@outlookpublishing.com Sales Director: Nick Norris nick.norris@outlookpublishing.com Operations Director: James Mitchell james.mitchell@outlookpublishing.com PROJECT DIRECTOR Tom Cullum tom.cullum@outlookpublishing.com PROJECT MANAGERS David Knott david.knott@outlookpublishing.com Sam Love sam.love@outlookpublishing.com HEADS OF PROJECTS Callam Waller

Hello and welcome The COVID-19 pandemic is one of the most challenging and disruptive events in history with its impact felt across the globe. However, with a life-saving vaccine now in the midst of being introduced worldwide, we’ve compiled a COVID-19 handbook which provides commentary from industry experts at EMBALL’ISO, Hanhaa, Air France-KLM Cargo, MIC Cargo and Validaide about the measures taken to distribute the vaccine and the major challenges to overcome. We are fortunate to have our part­ners and friends who are like-minded and came along with us for this project and we couldn’t have done this without them. This handbook lays out some practical areas we all can review and reflect on our own organization to improve and contribute positively to the big picture. David Bang Global VP of Strategic Development, Hellmann Worldwide Logistics

callam.waller@outlookpublishing.com Thomas Arnold thomas.arnold@outlookpublishing.com Vivek Valmiki vivek.valmiki@outlookpublishing.com TRAINING & DEVELOPMENT DIRECTOR Eddie Clinton eddie.clinton@outlookpublishing.com

CON T R IBU TOR S EMBALL’ISO YANN MARTIN, GLOBAL SALES DIRECTOR

SALES MANAGERS Donovan Smith donovan.smith@outlookpublishing.com Josh Hyland josh.hyland@outlookpublishing.com Ryan Gray

HANHAA HENNING POTTHARST, PRODUCT MANAGER

ryan.gray@outlookpublishing.com

ADMINISTRATION Finance Director: Suzanne Welsh suzanne.welsh@outlookpublishing.com Administrative Assistant: Sophia Curran sophia.curran@outlookpublishing.com

AIR FRANCE KLM MARTINAIR CARGO MARCEL KUIJN, GLOBAL HEAD OF PHARMACEUTICAL LOGISTICS

Office Manager: Daniel George daniel.george@outlookpublishing.com CONTACT North America Outlook East Wing, Ground Floor, 69-75 Thorpe Road, Norwich, Norfolk, NR1 1UA, United Kingdom.

MIC CARGO EDIP PEKTAS, CEO

Sales: +44 (0) 1603 959 652 Editorial: +44 (0) 1603 959 657 SUBSCRIPTIONS Tel: +44 (0) 1603 959 657 Email: sean.galea-pace@outlookpublishing.com www.northamericaoutlookmag.com

VALIDAIDE EELCO DE JONG, MANAGING DIRECTOR

SPRING 2021 | 3


Meinhardt EPCM | Thai Optical Group

GRAND CEREALS | BASIL READ MINING

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LAFARGE CANADA

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Issue 87

ATRADIUS TRADE CREDIT INSURANCE

A sustainable, innovative, and people-centric approach to construction

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I s s u e 47

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ASteward of the

Community

Pioneering trade credit insurance in America

SAINT JAMES HOSPITAL GROUP Innovation and adaption through COVID-19

Living Smart

Siam City Cement Public Company Limited (SCCC or INSEE) continues to show strength and compassion for its local communities despite the challenges presented by the COVID-19 pandemic

How Uber continues to leverage the power of technology to bring smarter solutions to several African markets, not only in the field of travel, but much further and deeper into the communities it serves

As the oil and gas industry recovers from the effects of the coronavirus pandemic, we report on an innovative new route for Exmar Offshore

STANDING SIDE-BY-SIDE WITH SLOVENIA

Against the backdrop of the global pandemic, we preview Hellmann Worldwide Logistics’ COVID-19 handbook

Orange’s Patrick Roussel examines the numbers of unbanked across Africa and how mobile money could solve the problem

Nadya Krisko of Honeywell Aerospace explains why COVID-19 has seen the private jet increase in popularity

Richard Browning, the man inside the ‘Iron Man’ suit, tells us the story behind monetising the idea into Gravity Industries

Hellmann Worldwide Logistics’ COVID-19 handbook Against the backdrop of the global pandemic, we preview

across Africa and how mobile money could solve the problem Orange’s Patrick Roussel examines the numbers of unbanked

COVID-19 has seen the private jet increase in popularity Nadya Krisko of Honeywell Aerospace explains why

the story behind monetising the idea into Gravity Industries Richard Browning, the man inside the ‘Iron Man’ suit, tells us

the communities it serves travel, but much further and deeper into African markets, not only in the field of technology to bring smarter solutions to several How Uber continues to leverage the power of

on an innovative new route for Exmar Offshore effects of the coronavirus pandemic, we report As the oil and gas industry recovers from the

construction approach to people-centric innovative, and A sustainable,

Smart Living

Tell us your story, Community and we’ll tell the world.

w w w. n o r t h a m e r i c a o u t l o o k m a g . c o m

Issue 01

circular economy A true pioneer of the

COMPOSAD HOLDING & SAVIOLA

through COVID-19 Innovation and adaption

HOSPITAL GROUP SAINT JAMES

ASteward of the

insurance in America Pioneering trade credit

INSURANCE TRADE CREDIT ATRADIUS

CANADA LAFARGE

SLOVENIA WITH SIDE-BY-SIDE STANDING

by the COVID-19 pandemic communities despite the challenges presented continues to show strength and compassion for its local Siam City Cement Public Company Limited (SCCC or INSEE)

SAVIOLA HOLDING & COMPOSAD

A true pioneer of the circular economy

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Issue 87

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North America Outlook, Africa Outlook, APAC Outlook and EME Outlook and are digital and print publications aimed at boardroom and hands-on decision-makers, reaching an audience of more than 800,000 people around the world; spanning the full range of industrial sectors. GRAND CEREALS | BASIL READ MINING

Meinhardt EPCM | Thai Optical Group

With original and exclusive content compiled by our experienced editorial team, we look to promote the latest in engaging news, industry trends and success stories from across the globe. Your company can join the leading industry heavyweights enjoying the free exposure we provide across both digital and print platforms with a free marketing brochure, extensive social media saturation, enhanced B2B networking opportunities, and a readymade forum to attract new investment and to help you grow your business. Visit www.outlookpublishing.com/work-with-us for details on how your company can feature for free in one of our upcoming editions.

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COVID-19 VACCINE LOGISTICS HANDBOOK

CONTENTS PREVIEW 6 Hellmann Worldwide Logistics Rising to the Challenge

Hellmann’s COVID-19 Vaccine Logistics Handbook preview and navigating the logistics industry post-COVID-19

SECTION 1 12 Logistics company introductions EMBALL’ISO, Hanhaa, Air France KLM, MIC Cargo and Validaide provide an insight into its services and how their offerings help assist the healthcare sector with its toughest challenge – COVID-19

SECTION 2 16 Preparing for vaccine distribution The five companies discuss the strategies introduced to ensure the efficient roll-out of the COVID-19 vaccine

SECTION 3 20 Distribution challenges Examining the potential problems that could disrupt the roll-out of the COVID-19 vaccine

SECTION 4 24 Advice on planning operations The companies offer advice to pharmaceutical manufacturers keen to contribute to this global effort

SECTION 5 26 Practical values An overview of each company’s capabilities and what their respective organizations can offer to the logistics industry

SECTION 6 28 Looking ahead into 2021 An insight into the challenges ahead during 2021 as the vaccine continues to be introduced at scale

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HELLMANN WORLDWIDE LOGISTICS

COVID-19:

Rising to the Challenge Against the backdrop of the COVID-19 pandemic, we preview Hellmann Worldwide Logistics’ COVID-19 handbook and gain insight from David Bang, Global VP of Strategic Development at the organization Writer: Sean Galea-Pace Project Manager: Tom Cullum

6 | COVID-19 VACCINE LOGISTICS HANDBOOK


PREVIEW

T

he COVID-19 pandemic has created a multitude of obstacles during the course of 2020. This has propelled businesses across the world to rethink operations and adopt agile approaches to business in order to deal with the ever-changing global situation. However, despite such disruption from both a human and a business perspective, a vaccine for the deadly disease has been announced and is being rolled out throughout 2021. With the vaccine now declared safe for us, the logistics industry is tasked with HELLMANN WORLDWIDE LOGISTICS 10450 Doral Boulevard, Doral, Florida, USA Tel: +1 305 406 4500

US-Marketing@hellmann.com www.hellmann.com

AIR FRANCE KLM MARTINAIR CARGO www.afklcargo.com

EMBALL’ISO USA

130 Keystone Drive, Montgomeryville PA 18936 Tel: +1 267 687 8570 Ext 104 Fax: + 1 267 543 6737

customercare-us@emballiso.com www.emballiso.com

HANHAA

Unit 507, Cocoa Building, The Biscuit Factory 100 Drummond Road, London SE16 4DG, United Kingdom info@hanhaa.com

www. hanhaa.com

MAESTRO CARGO

837 Patton Drive – Door C Chicago, IL 60666 Tel: 773.570.6432

www.maestrocargo.com

VALIDAIDE

Johan Huizingalaan 400 1066 JS Amsterdam The Netherlands www.validaide.com

COVID-19 VACCINE LOGISTICS HANDBOOK SPRING 2021

distributing the vaccine to the most vulnerable as efficiently as possible. Anticipated to be a mammoth task, the Pfizer vaccine for instance, is unable to travel above -70°C more than four times which means logistics companies such as Hellmann are vital. Some other vaccines are suitable to be transported at more modest temperature ranges like +2 to +8°C or -20°C, but transporting safely billions of doses globally in addition to all other vaccines and healthcare products as well as all other commodities based on

PRODUCED BY NORTH AMERICA OUTLOOK MAGAZINE

PRODUCED BY NORTH AMERICA OUTLOOK MAGAZINE

www.validaide.com The Netherlands 1066 JS Amsterdam Johan Huizingalaan 400

VALIDAIDE www.maestrocargo.com Tel: 773.570.6432 Chicago, IL 60666

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HELLMANN WORLDWIDE LOGISTICS

David Bang is the Global VP of Strategic Development at Hellmann Worldwide Logistics stronger economic return in 2021 and 2022, it will surely be one of the most challenging and critical temperature controlled logistics tasks we’ve ever seen. Logistics has been one of the industries that has undergone the most disruption. As an influential part of value chains, both within and across international borders, logistics firms facilitate trade and commerce while helping businesses get their products to customers. Initially, the impact of COVID-19 was felt in Asia as a result of the role the region plays in global manufacturing. With over 200 of Fortune Global 500 firms having a presence there, this meant that disruptions to manufacturing in the country then caused issues across global supply chains. For example, cargo was backlogged at China’s major container ports as travel restrictions led to a shortage of truck drivers picking up containers and ocean carriers cancelled sailings. Subsequently, the pandemic spread to the rest of the world and led to lockdowns and border closures which restricted the movement of goods worldwide.

For example, air cargo capacity significantly reduced globally and decreased by around 60 percent overall. Now capacity is slowly recovering although in many cases still volatile, and we have a monumental task in front of us to distribute COVID-19 vaccines from production to point of care for at least 70-80 percent of global population for herd immunity in every corner of the world, regardless of economic or geo-political bases. As a result, Hellmann Worldwide Logistics has compiled a COVID19 handbook which provides commentary from industry experts at EMBALL’ISO, Hanhaa, Air France-KLM Cargo, MIC Cargo and Validaide about the measures taken to distribute the vaccine and the major challenges to overcome. Founded in 1871, Hellmann Worldwide Logistics has become one of the largest privately-owned international logistics providers.

SQA SQA works with its client partners and their supply chains in over 70 countries annually, with over 1,000 quality professionals. SQA understands the complexity and challenges of a global supply chain and our clients count on us to extend their reach, uphold their name, and ultimately protect the patient. Annually, SQA performs over 3,000 audits, provides component inspection of over 1m parts at the source, and 50,000 hours of engineering supplier development. This occurs in the form of managed programs at supplier sites that include, but may not be limited to: audit, assessments, supplier development, part approvals, inspection, remediation, desktop evaluation and full time surveillance. We’re excited to share the SQA’s outsourced risk management “partnership”. We have boots on the ground worldwide allowing SQA to accommodate even the most complex supply chains.

www.sqaservices.com

HELLMANN HISTORY 1925 - In Germany, Hellmann was one of the first companies to replace their horse-drawn fleet with coal-powered trucks

8 | COVID-19 VACCINE LOGISTICS HANDBOOK

2006 - Hellmann receives the coveted ‘Award of Excellence’ from the Global Institute of Logistics 1968 - With 20 years of post-war expansion across Europe, the company’s shares were transferred to the fourth generation, Klaus and Jost Hellmann


PREVIEW

SQA has a global footprint that supports critical supply chains. We are a leader in assessing, monitoring and improving supplier quality for our client partners. The partnerships SQA has created over the past 25 years have provided benefits for our clients integrated strategies where SQA supports on a flexible, long-term basis. For industries where quality survives!

For industries where quality survives

+1 800-333-6180 (USA) | improve@sqaservices.com | www.sqaservices.com

2017 - With the foundation of the legally independent business units Air & Sea, Road & Rail and Contract Logistics as well as the Holding company, Hellmann reacts to the changing market conditions and its own Group size - initially on a national level, from 2018 also internationally

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HELLMANN WORLDWIDE LOGISTICS Through its partner network, the organization is represented across the globe, with around 20,500 employees across 489 offices in 173 countries. Its range of services includes classic forwarding services by truck, rail, air and sea freight, as well as a comprehensive offer for CEP services, contract logistics, industry and IT solutions. David Bang is the Global VP of Strategic Development at Hellmann Worldwide Logistics. He recognizes that 2020 was a challenging year in the supply chain and stresses that lessons have been learnt. “From a supply chain and logistics point of view, the year 2020 clearly showed that, even with many advanced technology advancements, there are

“THE HANDBOOK ISN’T A CONSULTING OR ACADEMIC PAPER BUT RATHER PRACTICAL CONTENTS THAT ARE HELPFUL TO TRANSPORT THE COVID-19 VACCINES SAFELY, SECURELY AND COST-EFFECTIVELY FROM PRODUCTION SITES TO POINT OF CARES” – DAVID BANG , GLOBAL VP OF STRATEGIC DEVELOPMENT still many vulnerabilities in our global supply chain,” he explains. “There was the toilet paper fiasco as well as other consumables you couldn’t find on the local grocery shelves, PPE shortage, etc. However, let’s not forget that there have been nearly one and a half million lives lost globally (as of early December 2020) and millions of other

10 | COVID-19 VACCINE LOGISTICS HANDBOOK

people’s lives have been turned completely upside and down. Although it is not just about the supply chain issue alone, we must learn and improve.” Most governments have responded to the crisis by designating ports, shipping and trucking services as essential and exempting them from


PREVIEW

The Pfizer vaccine is unable to travel at temperatures above -70°C, which means logistics companies, with capabilties such as Hellmann, are vital

lockdown rules. For example, the Indian government exempted the movement of cargo through ports, supply chains and the transport of essential commodities from lockdown rules. While lots of airports worldwide remain closed to passenger flights, most still remain open to cargo flights. Even prior to COVID-19, almost 30 percent of global vaccines annually had supply chain and logistics issues, according to GAVI. “And that was only for a two billion dose operation,” says Bang. “Now, with an almost 15 billion dose operation for COVID-19, we need to work and collaborate much better. Hellmann plays an important role in this and wanted to lay out a practical path forward that can benefit many others (even if some of them may be our competitors). “We are fortunate to have our partners and friends who are like-minded and came along with us for this project and we couldn’t have done this without them. This handbook lays out some practical areas we all can review and reflect on our own organization to improve and contribute positively to the big picture.”

Even prior to COVID-19, almost 30 percent of global vaccines annually had supply chain and logistics issues. “Now, with an almost 15 billion dose operation for COVID-19, we need to work and collaborate much better”

Bang points out that the handbook isn’t a consulting or academic paper but rather practical contents that are helpful to transport the COVID-19 vaccines safely, securely and costeffectively from production sites to point of cares, while also adding that Hellmann’s handbook caters to a wide demographic. Also, it covers multiple transport mode situations such as air, sea, and road as well as warehousing and last mile deliveries “You may be with a local government, a logistics company, a distributor, ministry of health, a vaccine producer, or a supplier to a vaccine producer,” he explains. “It’s important that they

are equipped with practical and costefficient guidance on how to prepare, execute and measure the cold chain logistics of COVID-19 vaccines for the top objective, product integrity and patient safety.”

HELLMANN WORLDWIDE LOGISTICS Tel: +1 305 406 4500 US-Marketing@hellmann.com www.hellmann.com

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SECTION 1 - LOGISTICS COMPANY INTRODUCTIONS EMBALL’ISO, Hanhaa, Air France KLM, MIC Cargo and Validaide provides an insight into its services and how its offerings help assist the healthcare sector with its toughest challenge – COVID-19.

1

Briefly introduce us to your organization and how it contributes to the healthcare industry.

EMBALL’ISO YANN MARTIN, GLOBAL SALES DIRECTOR As a cold chain specialist, EMBALL’ISO has been working closely with pharmaceutical laboratories, clinical trial operators, logistics companies, and last mile specialists to manage and control cold chain risks for 30 years. Founded in 1990, EMBALL’ISO has always strived to develop high performance products adapted to the needs of pharmaceutical laboratories as well as turnkey solutions for the temperature-controlled transport of pharmaceuticals.

EMBALL’ISO has been working closely with pharmaceutical laboratories over the past 30 years

12 | COVID-19 VACCINE LOGISTICS HANDBOOK

During the last 30 years, EMBALL’ISO has expanded to four continents with eight factories (Brazil, China, France, Germany, India, Singapore, the UK, and the US) and 14 service hubs allowing both a global supply and – more importantly – the introduction of reuse networks for insulated packaging on an international level.

HANHAA HENNING POTTHARST, PRODUCT MANAGER Hanhaa, is a leading British Internet of Things (IoT) innovator and private LTE/5G network supplier. Our first integrated solution, ParceLive, is a real-time cargo tracking service that connects users via the secure Hanhaa XG network to live information about the location, condition, and security of their assets regardless of their country, method of transport, carrier, or scale. The healthcare industry continuously fights to solve the common supply chain management challenges it faces, including the lack of real-time package tracking solutions, optimizing time-critical shipments, and securing environmentally sensitive medicine. Unfortunately, the outcome of this problem often comes down to costly services for the end recipients. Patients, the most vulnerable category, become the bumpers for unforeseen circumstances in the supply chain. When a sensitive package such as an implantable medical device needs to arrive at its destination from the manufacturer to the patient, every hour counts. For blood from matching donors, hours turn into minutes. The same of course can be said for life saving vaccines. Here, it is vitally important to make the best use of precious time.


COVID-19 VACCINE LOGISTICS HANDBOOK

AIR FRANCE KLM MARTINAIR CARGO MARCEL KUIJN, GLOBAL HEAD OF PHARMACEUTICAL LOGISTICS Air France KLM Martinair Cargo is the specialized air cargo business of the Air France-KLM Group. We offer a worldwide network of 457 destinations from our two hubs, Paris Charles de Gaulle, and Amsterdam Airport Schiphol. Post-pandemic, our long-haul network covers around 100 destinations around the globe, which we are serving with more than 600 weekly frequencies. Currently, we are close to 6,000 cargo only flights. In February 2016, Air France KLM Martinair Cargo became the first major airline to receive the IATA CEIV certification, adhering to a program of continuous improvement, specifically dedicated to airfreight. Giving priority to the pharmaceutical segment, we provided commitment to distributing healthcare products all over the world over the years and contribute to the well-being of the population.

Air France KLM Martinair Cargo offers a worldwide network of 457 destinations from its two hubs: Paris Charles de Gaulle and Amsterdam Airport Schiphol

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SECTION 1 - LOGISTICS COMPANY INTRODUCTIONS

EMBALL’ISO

Pioneer of Reuse and Reverse Logistics As a cold chain specialist, EMBALL’ISO has been working hand in hand with pharmaceutical laboratories, clinical trial operators, logistics companies, and ‘last mile specialists’ to manage and control cold chains risks for 30 years.

High Performance Isothermal Packaging and Services Provider Founded in 1990 by its current owner and CEO, EMBALL’ISO has always strived to develop high performance products adapted to the needs of pharmaceutical laboratories as well as turnkey solutions for the temperature-controlled transport of pharmaceuticals.

Worldwide Network Within 30 years, EMBALL’ISO has expanded to four continents with eight factories (Brazil, China, France, Germany, India, Singapore, the UK, and the US) and 14 service hubs allowing both a global supply and – more importantly – the introduction of reuse networks for insulated packaging on an international level.

Reuse and Reverse Mutualised Network

EMBALL’ISO’s pallet shipper range showing their design flexibilty in container stacking

MIC CARGO EDIP PEKTAS, CEO MIC Cargo provides ground handling services for our airline partners at Chicago O’Hare International Airport. Our 12,000 square-feet three-chamber facility is the only GDP-certified complete pharmaceutical cooler at ORD. MIC’s continuous cool chain within our warehouse is also unique among ORD ground handling service suppliers. Our many carrier customers include the likes of Emirates SkyCargo, and Air China Cargo, while Air China recently won a new healthcare business as a result of their partnership with us.

VALIDAIDE EELCO DE JONG, MANAGING DIRECTOR

EMBALL’ISO collects insulated packaging after use, groups returns from different customers, and sends the packaging back to the nearest EMBALL’ISO service centre through the solution with the lowest carbon footprint. The packaging is then disinfected, repaired if necessary, and checked to ensure that it guarantees the same level of protection as the new packaging. This ethical model allows EMBALL’ISO’s customers to benefit from the economies of scale created by the grouped returns and means they no longer have to manage the packaging once it has been used. With an innovative reuse and reverse business model that has already proven itself, the EMBALL’ISO model is much appreciated by customers, and works well thanks to a large network and collection points in over 80 countries. EMBALL’ISO helps you reuse isothermal packaging, while saving time and money.

Dynamic Approach EMBALL’ISO’s cold chain experts help pharma companies, logisticians, and airlines select the right protection depending on the lane, stability data, and weather conditions. It is called a dynamic approach. Thanks to EMBALL’ISO, and TLX by EMBALL’ISO, a large range of products (premium+, premium, standard, and protective) from thermal blankets to pallet shippers, with phase-change material, customers can choose the isothermal solutions to fit its real shipment needs.

High Experience of Scalability EMBALL’ISO’s pallet shipper’s easy design allows expansion on a largescale to follow the COVID-19 surge, with no production quantity limits. The existing fleet can be increased quickly for COVID-19 vaccine shipments. Repositioning is most often made by sea, and at no extra charge for customers.

At a Glance • 180 employees

Validaide provides a digital platform to manage global distribution networks for pharmaceutical manufacturers and their logistics partners, helping to reduce transport risk and accelerate the approval of transport routes. Our Digital Lane Manager application includes Lane Assessments and SOPs (Standard Operating Procedures) that use the information available from our Capabilities Platform. On this platform, hundreds of logistics providers define and share information about their infrastructure and processes to handle pharmaceutical products. 14 | COVID-19 VACCINE LOGISTICS HANDBOOK

• 30 years in 2020 • Eight production sites on four continents • 14 services hubs • Collection in more than 80 countries • Large range of isothermal packaging: from -80°C to +15°C/+25°C

www.emballiso.com


SECTION 2 - PREPARING FOR VACCINE DISTRIBUTION The distribution of the COVID-19 vaccine is an enormous task, perhaps the biggest the logistics industry has ever experienced. On the frontline, EMBALL’ISO, Hanhaa, Air France KLM, MIC Cargo and Validaide discuss the strategies introduced to ensure the efficient rollout of the vaccine.

2

What specific measures are you taking to prepare for, or support, COVID-19 vaccine distribution and logistics?

EMBALL’ISO YANN MARTIN, GLOBAL SALES DIRECTOR First of all, we’ve worked on our product portfolio: • New product development with high performance material and refrigerants (PCM Phase Change Material). • Adaptation of our existing range of products to new specifications. • Tests and validation under customer profiles. Then we decided to implement a COVID-19 taskforce to define our additional production capacities with strategic locations such as Indianapolis, Singapore, or Shanghai. We have the capacity to produce in our eight factories on four continents (North America, South America, Asia, and Europe) and it will help us to deliver quickly for our customers. Our already existing process allow us to increase quickly and scale production capacity. Raw material has been stored in advance and some specific plans as been built our key supplier to match various scenarios of scale up. In short: • Unique footprint matching worldwide pharma production for COVID-19 key production position in India, China, USA and Europe. • High experience of scalability: large capacities of production already existing. • Ability to rise production quickly: extension of actual production site in the existing production sites with well-established, controlled processes and know-how. • Already existing reconditioning facilities. 16 | COVID-19 VACCINE LOGISTICS HANDBOOK

• Preconditioning facilities worldwide for quick implementation.

HANHAA HENNING POTTHARST, PRODUCT MANAGER While Hanhaa’s first integrated solution, ParceLive, is a real-time cargo tracking service, on the hardware side, we are diligently preparing our equipment to have the robust battery life and the wider temperature ranges including deep frozen. For the software, we are becoming more proactive and predictive based on massive amount of data we are collecting and have access to.

AIR FRANCE KLM MARTINAIR CARGO MARCEL KUIJN, GLOBAL HEAD OF PHARMACEUTICAL LOGISTICS In June 2020 we created an internal, cross-disciplinary task force with the goal of preparing for the distribution of COVID-19 vaccines and medicines. At that time there was little information available so we worked on different scenarios. Today we have a reasonably clear picture on what to expect. The task force worked on different domains including capacity (in the air and on the ground) and readiness of suppliers and outstations. One of the deliverables of the task force was a dedicated product for the distribution of COVID-19 vaccines. Besides the highest priority it also provides access to a 24/7 service center that we have set up specifically for COVID-19 vaccine shipments. Another deliverable was the capacity increase of temperature controlled storage rooms both at Paris Charles-de-Gaulle and Amsterdam Schiphol.


COVID-19 VACCINE LOGISTICS HANDBOOK


SECTION 2 - PREPARING FOR VACCINE DISTRIBUTION

MIC Cargo With an experienced leadership team and over 160,000 square feet of modern facility space, MIC Cargo provides the highest quality handling service for passenger, freighter and charter flights at Chicago O’Hare International Airport.

MIC CARGO EDIP PEKTAS, CEO A challenge of this magnitude requires multi-level collaboration and quick adaptation to new ways of operating. As a company, we reached out to clients such as Hellmann, Envirotainer, and Emirates SkyCargo – and also to some competitors – to formulate best practices to complement our existing GDP certification. Specifically, in the near future, we plan to have new freezer space for approximately 900 skids to accommodate the specific needs of COVID vaccines. We have calibrated our facility temperature control systems with enhanced risk-prevention measures, and we have implemented additional redundancies on mechanical and human resource level to ensure a stable environment. Since our people are our most valuable asset, and there is nothing more important than their safety and health, we have implemented workplace standards recommended by the CDC to prevent virus transmission and maintain healthy operations. Conducting our business requires our employees to interact with each other and our customers in person. To keep everyone as safe as possible and avoid any business closures, we are piloting a Bluetooth-enabled contact tracing technology called Contact Harald. This system can quickly and accurately identify and contact those who have been exposed to the COVID-19 virus.

We offer the only GDP-certified pharmaceutical cooler at ORD, and our unbroken in-facility cool chain is unique to MIC as well. These features, along with our commitment to quality and collaboration, make us the preferred choice of pharmaceutical and health care shippers and forwarders at ORD. We know that combining speed and flawless performance is essential, so we deliver streamlined processes and reduced turnaround times while maintaining the strictest safety and security standards. Our processes are tailored to customers’ individual needs, and we recognize that 24/7 availability of accurate shipment information is key to superior customer service. Any handler can move your shipments – we want to move your business to the next level of success.

VALIDAIDE EELCO DE JONG, MANAGING DIRECTOR Validaide is actively working with our global community of air carriers, Ground Handling Agents, and warehouse and trucking providers to ensure that pharma handling capabilities are defined and up to date on the Validaide platform. We also encourage these logistics suppliers to upload additional information about their facilities, such as images and certificates. The information available on Validaide supports freight forwarders in the planning and approval of COVID-19 vaccine transport networks, specifically to evaluate logistics suppliers and transport options. 18 | COVID-19 VACCINE LOGISTICS HANDBOOK

Tel: 776-570-6432


MIC Cargo

Operating the only GDP-certified pharmaceutical cooler at ORD

Best-in-class quality with over 160,000 square feet of modern facility space

Providing the only unbroken in-facility cool chain at ORD

12,000-square-foot, 3-chamber cooler with next-generation control and monitoring technology

The clear choice for superior handling of pharma and health care at Chicago O’Hare

Contact us at 773-570-6432 We will exceed your expectations!


SECTION 3 - DISTRIBUTION CHALLENGES With the roll-out of the vaccine well underway, transporting it has come with its challenges. For example, the Pfizer vaccine must always be stored at a temperature below -94°C, which when transported to hot climates, cannot be 100 percent guaranteed, posing considerable challenges. EMBALL’ISO, Hanhaa, Air France KLM, MIC Cargo and Validaide examines the potential problems that could disrupt the roll-out of the COVID-19 vaccine.

3

What major challenges relating to the distribution of COVID-19 vaccines will need to be overcome?

EMBALL’ISO YANN MARTIN, GLOBAL SALES DIRECTOR

HANHAA HENNING POTTHARST, PRODUCT MANAGER

There are four main challenges to overcome: 1. Firstly, to maintain the right temperature till patient. With incoming vaccines such as the Moderna and Pfizer vaccines, the final distribution and administration remains a big challenge.

The distribution of COVID-19 vaccines is one of the most logistically difficult operations the world has ever seen. Not only will distribution be a chaotic task, but the storage conditions of the vaccine may prove to be even more troublesome. Pfizer’s vaccine needs to be stored at -94°C (-137.2F). Pharmacies don’t have freezers this cold, because no approved drug has ever needed to be held at this temperature. Even if it were possible for countries across the globe to manage this, the stability of the vaccine is not 100 guaranteed when exposed to slight climatic variations. With that being said, Pfizer is working on a powdered version of its vaccine in hopes of reducing cold storage requirements this year. The other leading candidate from Moderna and the National Institute of Allergy and Infectious Diseases could be kept at -20°C. Alongside this, the vaccine will initially be a target for theft and diversion due to limited supplies and high demand. Without efficient and cooperative regulatory systems, there is a much higher risk that inferior and counterfeit vaccines will appear on the market. Support and innovation are urgently needed to prevent substandard and counterfeit vaccines entering the supply chain and undermining trust in formal delivery mechanisms.

2. Secondly, the capacity. If billions of doses of vaccines have to be sent at the same time, there might not be enough aircraft capacity or isothermal solutions, while not even mentioning the other medicines that need to be shipped too. Multimodal shipments with sea shipments should be taken into consideration too. 3. Thirdly, in order to supply this vaccine, all stakeholders will have to work closely and collaborate. Storage capacity are not the same everywhere. There might not exist or be limited, High Quality Temperature Controlled AWB might not be available on charter flights. 4. Lastly, even if the vaccine distribution is a priority, the impact on the environment needs to be taken into account. Reusable Solution should be prioritised to avoid waste landfill. Reuse and Reverse Model like the one we offer is well adapted with less CO2 emission due to the light weight of the pallet shipper, reusability and scale up capacities. 20 | COVID-19 VACCINE LOGISTICS HANDBOOK


COVID-19 VACCINE LOGISTICS HANDBOOK

Parcelive - a real-time cargo tracking and monitoring solution

SPRING 2021 | 21


SECTION 3 - DISTRIBUTION CHALLENGES

Hellmann Worldwide Logistics Real-time and actionable transparency for your logistics flows at a fraction of the cost and with no complex IT set up. Air, ocean, road and rail. Domestic or international. All sizes. Various conditional requirements like geofencing, temperature, humidity, shock and tilt. From production sites to point of uses, through many handovers in between, Hellmann Smart Visibility help shippers and consignees transport their shipments like vaccines and many other sensitive commodities with confidence and peace of mind.

www.hanhaa.com/parcelive

MIC Cargo’s 12,000 square-feet three-chamber facility is the only GDP-certified complete pharmaceutical cooler at ORD

AIR FRANCE KLM MARTINAIR CARGO MARCEL KUIJN, GLOBAL HEAD OF PHARMACEUTICAL LOGISTICS In the beginning, the main challenge was the unknown... scenarios. At this point in time there is still uncertainty on precise timing and volumes so we will all need to be agile. Another challenge is the requirement to transport one of the vaccines at -80 degrees celsius. The large amount of dry-ice required for that made it necessary to review our processes and determine how we can safely increase the amount of dry-ice that we can transport in our aircraft. We succeeded to do so but it was not a small task.

MIC CARGO EDIP PEKTAS, CEO The biggest challenge is transporting billions of doses of COVID-19 vaccine worldwide and it is the largest and most important logistics effort in history. Considering the manpower and payload needed, plus the extreme temperature-sensitivity of the product, then factoring in the urgency of reducing the global impact of the virus, it adds up to formidable task – but also a tremendous opportunity.

22 | COVID-19 VACCINE LOGISTICS HANDBOOK

www.hellmann.com

Among the major challenges are: • Most cargo travels in the bellies of passenger aircraft, and many of the usual routes are not currently operating due to reduced passenger demand. • The same reduction in demand has resulted in a reduction of manpower at airlines and many other cargo industry organizations. • Employees participating in this unique supply chain will need specialized training – for their safety and to ensure the integrity of the vaccine delivered to the public. • While the specialised packaging needed to transport and maintain the vaccine at sub-zero temperatures is currently in use, this packaging is not available in the quantities that will be needed for the vaccine transport. The same is true for the amount of warehouse freezer space that will be required at transfer and distribution points.


COVID-19 VACCINE LOGISTICS HANDBOOK

Transparency in real-time With Hellmann Smart Visibility you will receive all the information about the condition of your consignment, anytime, anywhere. Make transparency your added value. The intelligent way of tracking. Contact Henning Pottharst | Product Manager Smart Visibility Phone: +49-541-605-6373 | E-Mail: henning.pottharst@hellmann.com www.hellmann.com www.hanhaa.com/parcelive

“COVID-19 VACCINES ARE TEMPERATURE-SENSITIVE AND WILL NEED TO BE SHIPPED AND STORED IN TEMPERATURECONTROLLED ENVIRONMENTS”

VALIDAIDE EELCO DE JONG, MANAGING DIRECTOR A major challenge is ensuring the vaccines are stored in temperature-controlled environments. Ensuring product integrity will be critical, which can only be ensured with the right combination of thermal packaging and adequate infrastructure, equipment, processes, and trained staff during global distribution. All parties need to agree and provide approval on these topics for all transport routes, while also ensuring regulatory compliance. Additional challenges for the distribution of COVID-19 vaccines are expected to be related to capacity constraints in air freight and road freight, customs clearance and security.

MIC Cargos’s continuous cool chain within its laboratory study is also unique among ORD ground handling service suppliers As the number of passenger flights remains below preCOVID levels, air freight capacity and route networks are also significantly reduced. This needs to be addressed with additional freighter flights and a growing number of charter flights from forwarders. Governments will also need to define fast-track procedures to expedite the import clearance of COVID-19 vaccines. Finally, arrangements need to be in place to prevent tampering and theft of COVID-19 vaccines during global transportation. SPRING 2021 | 23


SECTION 4 - ADVICE ON PLANNING OPERATIONS Pharmaceutical manufacturers must provide guidance to the logistics industry on supply chain planning to assist in the successful roll-out of the vaccine. EMBALL’ISO, Hanhaa, Air France KLM, MIC Cargo and Validaide offer its advice to pharmaceutical manufacturers keen to contribute to this global effort.

4

In light of these concerns, what advice would you give to pharmaceutical manufacturers and their suppliers (raw materials, CMO, 3PLs etc.) in order to plan and execute such an operation effectively?

EMBALL’ISO YANN MARTIN, GLOBAL SALES DIRECTOR The first thing would be to work on the stability of data of their pharma products. This allows us to make huge savings while offering not the most performant solution but the one that will be sufficient to their needs. Through our dynamic approach, we advise customers on the level of performance they need depending on lanes and stability data of the product. It is also important to communicate in advance on production and needs so that all actors (forwarders, packaging supplier) can adapt their production plan or services centres capacities, even if they’re already anticipated.

HANHAA HENNING POTTHARST, PRODUCT MANAGER To execute such an operation effectively will require a range of strong oversight tools to be in place before vaccinations are distributed. Multiple options are available, from technology-based approaches such as IoT and blockchain which would help prevent theft and assure the quality of vaccines. And with technology becoming increasingly more sophisticated and easily accessible by nefarious manufacturers and shippers alike, pharmaceutical manufacturers and their suppliers should identify pain points, run proactive tests and exercises to predict criminal behaviour, and, of course, put in preventative measures. 24 | COVID-19 VACCINE LOGISTICS HANDBOOK

EMBALL’ISO was founded in 1990

Hellmann and Hanhaa recognizes that some companies, especially those the size of Johnson & Johnson or Pfizer, might feel the need to deploy entire armies in the fight against counterfeit drugs. Consider, for instance, that revenues from counterfeiting and diverting drugs accounts for around $200 billion, or 10 to 15 percent of the entire, global pharmaceutical market. Hellmann and Hanhaa notes that these pain points, while real, can be controlled by implementing Smart Visibility both upstream and downstream in the cold chain, or transit that requires end-to-end temperature control through transit. Not only does the Smart Visibility and ParceLive tracking system ensure compliance in this regard (and from between -30 to 50 degrees), but can also alleviate unnecessary and time-consuming war games by


COVID-19 VACCINE LOGISTICS HANDBOOK providing simultaneous, or real-time, updates on location, humidity, shipment breaches, unanticipated shocks, falls, tilts, and more. Despite all of these countermeasures, Hanhaa also notes the need to get out, and stay out, ahead of counterfeiters and diverters who are increasingly moving away from shipping actual counterfeit products and, instead, sending illegitimate ingredients to manufacturing facilities in order to produce fakes in country.

2. Lane Assessments

1. Digital Lane SOPs

3. Supplier Capabilities Capabilities Platform

AIR FRANCE KLM MARTINAIR CARGO MARCEL KUIJN, GLOBAL HEAD OF PHARMACEUTICAL LOGISTICS ‘Key to success’ It is also very important to communicate clearly on expectations in terms of quality, servicing and security to ensure that each party in the supply chain knows what is expected from them and there are no surprises.

MIC CARGO EDIP PEKTAS, CEO As noted above, at this point we do not know everything we need to know about the specific vaccine and what it will take to move it safely and effectively. But there are certain qualities that pharmaceutical manufacturers and their suppliers should demand from any prospective supply chain partners: The number one key is the potential partner must demonstrate the capability for, and a commitment to, open-source data sharing and collaboration.

Pharma Lane Management made easy

Accelerate transport planning, simplify change management and remain compliant with healthcare regulations www.validaide.com

The potential partner must have the proper facilities and the highly trained staff needed to effectively play their role in this critical effort. The potential partner must follow the existing industry standards and best practices for temperature-sensitive cargo. The potential partner must demonstrate an ability to modify their current existing processes (or quickly develop new ones) to meet the needs of unique shipments.

VALIDAIDE EELCO DE JONG, MANAGING DIRECTOR

A commitment to open-source data sharing and collaboration is essential

It is vital for pharmaceutical manufacturers to provide guidance to the logistics industry on supply chain planning and the thermal stability of their COVID-19 vaccines. A lot of this knowledge may still be evolving but any insights on thermal stability will support the distribution planning. A good example has been the information provided by Moderna on the temperature requirements for their mRNA-1973 COVID-19 vaccine candidate. This information can be used by manufacturers, freight forwarders and other partners to jointly define distribution networks as early as possible with adequate packaging solutions and the availability of sufficient transport capacity and infrastructure. SPRING 2021 | 25


SECTION 5 - PRACTICAL VALUES EMBALL’ISO, Hanhaa, Air France KLM, MIC Cargo and Validaide provide an overview of its capabilities and what their respective organizations can offer to the logistics industry.

5

What types of practical values do you think your organization can bring to the table? The repositioning is made most of the time by sea and by air in case of urgent cases. As a small and agile company, EMBALL’ISO works hand in hand with customers. We identify needs, implement dedicated solution to customer, open new services centres or conditioning centres. This helps to boost development to new customers that can benefit from solution or network and then it benefits to the first customers with mutualized costs. This is how we boost the development.

EMBALL’ISO YANN MARTIN, GLOBAL SALES DIRECTOR As a small and agile company, EMBALL’ISO offers TaylorMade solutions and flexibility as the Reuse and Reverse Network. EMBALL’ISO collects insulated packaging after use, groups returns from different customers, and sends the packaging back to the nearest EMBALL’ISO service centre through the solution with the lowest carbon footprint. The packaging is then disinfected, repaired if necessary, and checked to ensure that it guarantees the same level of protection as the new packaging. This ethical model allows EMBALL’ISO’s customers to benefit from the economies of scale created by the grouped returns and means they no longer have to manage the packaging once it has been used. With an innovative reuse and reverse business model that has already proven itself, the EMBALL’ISO model is much appreciated by customers, and works well thanks to a large network and collection points in over 80 countries. EMBALL’ISO helps customers reuse isothermal packaging, while saving time and money. 26 | COVID-19 VACCINE LOGISTICS HANDBOOK

HANHAA HENNING POTTHARST, PRODUCT MANAGER For all modes of transportation, regardless of sizes and temperature requirements, Smart Visibility has the right solution that is extremely user friendly and cost effective. It is why major pharmaceutical and medical device companies can easily deploy our solutions to their existing supply chain globally. Global COVID-19 vaccine logistics will have lots of variables such as locations, temperature ranges, transport modes, customs, temperature-controlled packaging types, and having a real time insight to all of these moving targets is one of the key values we bring to the table.


COVID-19 VACCINE LOGISTICS HANDBOOK AIR FRANCE KLM MARTINAIR CARGO MARCEL KUIJN, GLOBAL HEAD OF PHARMACEUTICAL LOGISTICS Air France Cargo and KLM Cargo both have initiated and actively contributed to a community approach at their own hubs Charles de Gaulle and Schiphol. With a collaborative attitude, we can contribute to better prepare other actors in the chain to the upcoming distribution of COVID-19 vaccines and drugs.

MIC CARGO EDIP PEKTAS, CEO Earlier this year, MIC handled 16 cargo charters of COVID-related supplies (PPE and other medical-related equipment). This included three pharma-only charters totalling 220 metric tons. MIC’s exclusive unbroken in-warehouse cool chain and GDP-certified, three-chambered 12,000 square-feet cooler kept these pharma shipments at the strict temperature and humidity levels required. Next-generation, fully-automated technology allows us to monitor the temperature of all pharma we handle 24/7. MIC recognizes the importance of partnership and collaboration with all our business partners. From top leadership to warehouse staff, we stress the importance of taking ownership of every shipment – handling medicines and vaccines as if we or our family members were the end patient.

VALIDAIDE EELCO DE JONG, MANAGING DIRECTOR The Validaide digital platform can help to accelerate the planning and preparation of COVID-19 distribution activities for manufacturers and forwarders in multiple ways. First, our Validaide Capabilities Platform provides direct access to information about infrastructure, equipment, and processes of many logistics providers. This helps forwarders and manufacturers to easily evaluate and select qualified logistics suppliers and transport routes. For example, Validaide users can easily check if freezers or cold rooms are available at airports in Sydney or Melbourne when COVID-19 vaccines need to be shipped to Australia. This supplier information is automatically combined with other relevant data on Validaide, such as climate data and flight schedules. This enables users to easily create digital Lane Assessments, which are a regulatory

requirement for healthcare shipments and particularly important for temperature-sensitive products. In a recent project with Hellmann Logistics we created Lane Assessments for more than 250 transport routes of a pharmaceutical manufacturer within a few days. This provided a major time saving, as traditionally it would have taken weeks or months to collect information from all relevant suppliers and create manual assessments in Excel spreadsheets.

Validaide’s digital platform is used to scale the planning of COVID-19 distribution for manufacturers and forwarders in a number of ways

SPRING 2021 | 27


SECTION 6 - LOOKING AHEAD INTO 2021 With this year set to be one of the most challenging and demanding years ever for the logistics industry, EMBALL’ISO and Air France KLM provide guidance with the future in mind.

6

What are the other key things to be aware of during 2021?

EMBALL’ISO YANN MARTIN, GLOBAL SALES DIRECTOR Awareness of the destruction that human activities are inflicting on our planet makes it essential to move away from single use items, to stop throwing things away and to start reusing them. The COVID-19 vaccine distribution should not let it apart. Many pharmaceutical companies are exploring the potential for reusing insulated packaging. There are few calls for tender that do not compare single-use and reusable insulated packaging. However, reusing insulated packaging is viewed very differently depending on the customers, the suppliers, the types of packaging (active/ passive) and the countries. Suppliers of active insulated packaging or containers, which are inherently reusable and available only on a rental basis, eliminate the waste management problem. However, these products are heavy, very expensive to produce and rent, and are moved by plane (usually empty) in order to maximise their turnover rate. They have a significant impact on the environment, since they cause CO2 emissions into the atmosphere. Other hybrid models have been developed where the packaging supplier collects the passive insulated packaging at its destination and moves it flat, most often by boat. This is called reverse logistics. The environmental footprint is markedly smaller: moving by boat and 28 | COVID-19 VACCINE LOGISTICS HANDBOOK

reusing insulated packaging managed by the supplier. Changes in maritime transport regulations are making it increasingly less polluting, with the use of cleaner fuel and more stringent waste filtration systems. The next step is to develop the shortest possible reverse logistics routes, without moving to the point of origin, but rather with local movement to the nearest possible location. This is only feasible with a dense network and service centres on every continent. Pharmaceutical companies also need a guarantee that reused insulated packaging will maintain the same level of performance. This means establishing a complete traceability circuit for the units and developing a cleaning and repairs programme, validated and managed by the passive packaging supplier and incorporated into its quality system. The next step is consolidating/ mutualising the recovery of insulated packaging from the various end customers. This will increase the number of units per sea container, reducing the environmental footprint and the cost, all in a virtuous system. Few suppliers on the market can offer such comprehensive solutions that consolidate end-customer units, as it takes time to create a global reverse logistics network. This is a fundamental business change for insulated packaging suppliers, with a major focus on Supply Chain activities to optimize return flows and reuse programs. Another benefit of this


COVID-19 VACCINE LOGISTICS HANDBOOK

“...PARTNERSHIPS WILL BE ESSENTIAL. “TRADITIONAL PARTNERSHIPS” BETWEEN ISOTHERMAL PACKAGING SUPPLIER AND LOGISTICIANS FOR EXAMPLE, BUT ALSO BETWEEN ISOTHERMAL PACKAGING SUPPLIERS” cooperation is the possibility of recovering and reusing an increasingly wide range of insulated packaging: from box pallets to pallet shippers, with water or PCM briquettes, and thus lowering costs for everyone. Reusing passive insulated packaging with a global return consolidation system helps pharmaceutical companies reduce their waste management, transport and purchasing costs while improving their environmental footprint, with less waste and lower CO2 emissions associated with the creation of new packaging and transport.

Last but not least, in the challenging context of COVID19 distribution, partnerships will be essential. “Traditional partnerships” between isothermal packaging supplier and logisticians for example, but also between isothermal packaging suppliers. This will bring synergies and make it possible to propose global solutions adapted to the challenges.

AIR FRANCE KLM MARTINAIR CARGO MARCEL KUIJN, GLOBAL HEAD OF PHARMACEUTICAL LOGISTICS Sustainability is an important topic for society and in the logistics industry. Air France KLM Martinair Cargo has recently launched the world’s first sustainable aviation fuel (SAF) program in the airfreight industry, enabling freight forwarders and shippers to reduce their CO2 emissions. Several of our key customers have already signed up. Another topic that will continue to grow in importance is (real-time) connectivity. Both on the commercial side by connecting forwarders directly to our digital services as well as on the operational side using container and tracker data. SPRING 2021 | 29


COVID-19 VACCINE LOGISTICS HANDBOOK SPRING 2021 HELLMANN WORLDWIDE LOGISTICS 10450 Doral Boulevard, Doral, Florida, USA Tel: +1 305 406 4500 US-Marketing@hellmann.com www.hellmann.com

AIR FRANCE KLM MARTINAIR CARGO www.afklcargo.com

EMBALL’ISO USA 130 Keystone Drive, Montgomeryville PA 18936 Tel: +1 267 687 8570 Ext 104 customercare-us@emballiso.com www.emballiso.com

HANHAA Unit 507, Cocoa Building, The Biscuit Factory 100 Drummond Road, London SE16 4DG, United Kingdom info@hanhaa.com www. hanhaa.com

MIC CARGO 837 Patton Drive – Door C Chicago, IL 60666 Tel: 773.570.6432

VALIDAIDE Johan Huizingalaan 400 1066 JS Amsterdam The Netherlands www.validaide.com

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