The majority of the study population was female, reflecting the national gender ratio of pharmacists in the US. (14) Most respondents were middle-aged with decades of experience, enabling them to provide a longitudinal perspective on challenges to the profession. The mean self-assessed level of burnout was moderate, which aligns with previous findings. (15) A systematic review published in 2023 found that 51% of pharmacists worldwide experienced burnout. (16) In a 2024 study of pharmacists in the US Veterans Affairs (VA) health system, 72% reported moderate levels of burnout. (17) Table 2 – Mean Self-Reported Burnout by Practice Area Practice Area Mean Burnout Ambulatory care (n = 44) 6.09 +/- 2.21 Cardiology (n = 8) 5.63 +/- 2.20 Critical care (n = 11) 5.36 +/- 1.86 Geriatrics (n = 12) 5.67 +/- 2.87 Oncology (n = 12) 5.75 +/- 1.91 Psychiatry (n = 10) 3.70 +/- 2.11 Community pharmacy (n = 215) 6.53 +/- 2.58 Internal medicine (n = 56) 5.61 +/- 2.21 Specialty pharmacy (n = 6) 5.33 +/- 2.34 Healthcare administration (n = 7) 5.86 +/- 2.73 Managed care (n = 7) 4.00 +/- 3.16 Long-term care (n = 6) 2.83 +/- 2.14 Excludes practice areas with < 5 responses dardized B = 0.102, p = 0.032), while age was significantly and negatively correlated with burnout (standardized B = -0.202, p = 0.027). would help reduce burnout in your workplace? The most prevalent themes identified were workload management (54%), leadership and supervision (12%), work environQualitative analysis was used to ment and tools (9%), and work-life examine free responses to survey integration (9%). question #18: What additional resources, interventions, or changes Discussion The study confirms that pharmacists experience significant burnout, particularly in fast-paced, high-pressure environments where job expectations are constantly evolving. Our results align with existing literature showing that burnout is widespread among healthcare professionals, particularly pharma- Table 3 – Statistical Analysis of Select Survey Responses Survey Question Average hours worked per week > 40 Yes v No Years of experience > 20 Yes v No Primary work setting in person Yes v No Patient-facing role Yes v No Extended shift preference (Yes v No) Specialist (Yes v No) Q12 How does the amount of patient interaction required by your job affect your level of burnout? (1 = significantly increase, 5 = significantly decrease) 2.58 vs. 2.46 P = 0.177 2.68 vs. 2.39 P = 0.041 2.35 vs. 3.30 P < 0.001 2.09 vs. 3.51 P < 0.001 2.29 vs. 2.63 P = 0.018 3.15 vs. 2.35 P < 0.001 Q13 On a scale 1-10, how would you rate your overall level of burnout at work? (1 = no burnout, 10 = extreme burnout) 6.20 vs. 5.73 P = 0.055 5.75 vs. 6.14 P = 0.059 6.17 vs. 5.09 P < 0.001 6.28 vs. 5.27 P < 0.001 6.29 vs. 5.81 P = 0.055 2.40 vs. 2.59 P = 0.006 Q15 How often do you experience physical symptoms of burnout (e.g., fatigue, headaches, body aches, stomach/ intestinal issues, frequent illness, changes in appetite or sleep) due to your job? (1 = rarely, 5 = always) 3.11 vs. 3.01 P = 0.164 2.99 vs. 3.12 P = 0.095 3.16 vs. 2.64 P < 0.001 3.20 vs. 2.76 P < 0.001 3.20 vs. 2.99 P = 0.034 2.76 vs. 3.14 P < 0.001 Q16 How often do you feel that your workload negatively impacts your well-being? (1 = rarely, 5 = always) 3.23 vs. 3.02 P = 0.022 3.05 vs. 3.20 P = 0.062 3.23 vs. 2.67 P < 0.001 3.28 vs. 2.80 P < 0.001 3.32 vs. 3.04 P = 0.003 Independent t-test, two-sided p, equal variances not assumed Page 11 2.83 vs. 3.21 P < 0.001