More powerful breast cancer risk stratification for more personalized care Give high-risk patients the most comprehensive risk assessment For patients with a family history of certain cancers, MyRisk with RiskScore evaluates 48 genes associated with hereditary cancer risk to identify genetic changes associated with an increased cancer risk. When combined with family history and other clinical factors, MyRisk with RiskScore provides each patient with a comprehensive, personalized assessment of the five-year risk and remaining lifetime risk of developing breast cancer by combining personal and family history with breast cancer genetic risk markers and ancestry genetic markers. This makes MyRisk with RiskScore a powerful tool that helps you and your patients make more informed decisions to help prevent breast cancer or diagnose it at an earlier, more treatable stage.
How MyRisk with RiskScore uniquely stratifies risk to inform and personalize patient care
+ 48 hereditary cancer genes
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=
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Personal & family history
Breast cancer genetic risk markers
Ancestry genetic markers
Tyrer-Cuzick V8
93 breast cancer SNPs
56 ancestry SNPs
MyRisk + RiskScore
Get a powerful result to guide management options for your high-risk, unaffected patients* MyRisk with RiskScore: Improved risk stratification that’s 2x more predictive of breast cancer risk than Tyrer-Cuzick alone1,2
Greater predictive accuracy
80
! >130K
60 40
#1
20 0 RiskScore (TC+MA-PRS)
Tyrer Cuzick (TC)
Over half of patients who test negative for a hereditary cancer syndrome will have a change in medical management due to their family history of cancer and/or their RiskScore3 Validated technology with results you can trust based on outcomes data from >130,000 patients1,2,4-7 The first and only comprehensive breast cancer risk assessment that includes breast density, clinical factors, and a polygenic risk score validated for patients acr oss all ancestries4,6,8
*Patients whose management is indicated by a personal history of breast cancer, LCIS, hyperplasia, atypical hyperplasia, or a breast biopsy with unknown results are not eligible to receive a RiskScore. MA-PRS=multiple ancestry-polygenic risk score; TC=Tyrer Cuzick.