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PIE POST (APVRS 2021 Edition) - DAY 2

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2

ISSUE

posterior segment • innovation • enlightenment

12 | 13 | 21

PIE M A G A ZINE ’ S D A ILY CONGR E S S NE W S ON T HE P O S T E RIOR S E GME N T

HIGHLIGHTS ROP classification 04 The has been updated... check it out. of COVID’s long 05 Beware term effects on the retina!

On Spotlight at APVRS 2021 Virtual

Real World Progress on AMD and PCV by Joanna Lee

uveal melanoma to 08 From AI, and other tidbits from the trauma symposium.

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n Day 2 of the 14th Congress of the AsiaPacific Vitreo-retina Society (APVRS 2021 Virtual), all eyes were on the choroid.

Whether through the latest imaging technology or the ultra-widefield indocyanine green angiography (UW-ICGA), researchers are observing both its role in the development of neovascular age-related macular degeneration (nAMD) and its relationship with polypoidal choroidal vasculopathy (PCV). The availability of anti-VEGF treatment has been a major step forward for treating these conditions; however, real world data is vital in the effort to translate the success of clinical trial results into real world outcomes.

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3D-visualization of Haller vessels in pachychoroid

3D imaging to view choroidal vessels. “Now we can see specific individual vessels in more detail — you can see their wall, the diameter, changes in the diameter, and if there are any focal changes,” he said, while showing the vasculature of a patient’s eye with CSCR (central serous chorioretinopathy) in 3D. Currently, Dr. Chhablani and colleagues are working on the machine’s ability to demonstrate any nicking, constrictions and narrowing, while also making an effort toward providing more quantitative and qualitative analyses.

Pachychoroid disease and polypoidal choroidal vasculopathy

With 3D-visualization of Haller vessels in pachychoroid, choroidal imaging may never be the same again. Different from retinal vessels, choroidal vessels are challenging to observe due to shadows, their complex arrangement, and difficult vessel course delineation.

Dr. Gemmy Cheung presented her latest study, which investigated how venous overload choroidopathy may be a unifying mechanism that could explain the characteristics of pachychoroid diseases. Among pachy vessel segments in the posterior or in the peripapillary region (outer-periphery), they observed how these vessels often connect adjacent to

Dr. Jay Chhablani and his team has, with the help of machine learning algorithms, developed

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