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Marchesini Group_Process

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We at Marchesini Group are proud leaders in manufacturing and integrating

complete lines since 1974.

To complete the range of production machines for the pharmaceutical industry, the Group production plants Dott. Bonapace and Dumek allow Marchesini Group to supply processing machines for different types of products such as solids, capsules, tablets and creamy products.

Continuous improvement of existing solutions and research of new products and processes is the base of our philosophy for the design of solutions able to satisfy customers’ needs.

Keypoint

Biplanetary mixer for maximum homogenization efficiency

Ergonomic design

System for integrated and optimized heating and cooling, to maximize energy savings

Efficiency and Accuracy

Water consumption optimization during washing

User Friendly solutions

TURBOEMULSIFIERS, MIXERS AND MELTERS

Vacuum overpressure

PHARMA-MEK | OPENABLE & TILTABLE

Featured Model PHARMA-MEK 1000 with bi-planetary mixing unit

Vacuum turboemulsifiers suitable for processing liquid and creamy products.

VESSEL

• Openable lid

• Tilting vessel up to 3000

• Parts in direct contact with product in AISI 316 stainless steel

TEMPERATURE MANAGEMENT

• Vessel with inner double jacket with water/thermic fluids for heating and cooling

• Smart temperature control system (patented) for temperature curve design

• Possibility to insert thermoregulation unit within machine guards (optional) VACUUM

• Vacuum circuit with visual passage and liquid ring pump

EQUIPMENT OF THE VESSEL

• Funnel on the lid for auxiliary substances loading

• Sight-port equipped with glass-wiper and light-port with momentary light on the lid

• Tri-clamp connections and diaphragm valves on lid

MIXER

• Bi-planetary or slow coaxial mixing system (counter-rotating)

• Mixing blade with optimized profile for the vertical movement of product, including PTFE scrapers

• Variable speed of the Mixer through inverter TURBINE

• Homogenizing turbine - rotor/stator typeat the bottom of the vessel or external

• Variable speed of the turbine through inverter VESSEL UNLOADING

• Piston valve for the product unloading, placed at the bottom of the vessel

RANGE

25-3000 litres

SUPPORTING STRUCTURE

• AISI 304 stainless steel supporting structure with anti-vibration/self-levelling and adjustable support feet

OPERATOR PANEL

• Touch screen 12’’ operator panel with Siemens PLC

• Digital visualization of the process parameters

• Function for the continuous recording of process parameters: trends and datalogger (D-SCRIBA)

• CFR Part 11, Active Directory and validation package (optional)

ATEX CONFIGURATION

• ATEX certification for internal Zone 1 with nitrogen inertization and external Zone 2 (optional).

Vacuum overpressure

PHARMA-MEK | OPENABLE

VESSEL

turboemulsifiers suitable for processing liquid and creamy products.

• Fixed vessel with openable lid

• Parts in direct contact with product in AISI 316 stainless steel

DUAL TECHNOLOGY

• Either internal or external recirculation or a combination of both.

TEMPERATURE MANAGEMENT

• Vessel with double jacket filled with water/thermic fluids for heating and cooling

• Smart temperature control system (patented) for temperature curve design

• Possibility to connect thermoregulation unit (optional)”

VACUUM

• Vacuum circuit with visual passage and liquid ring pump

EQUIPMENT OF THE VESSEL

• Funnel on the lid for auxiliary substances loading

• Sight-port equipped with glass-wiper and light-port with momentary light on the lid

• Tri-clamp connections and diaphragm valves on lid

MIXER

• Bi-planetary or slow coaxial mixing system (counter-rotating)

• Mixing blade with optimized profile for the vertical movement of product, including PTFE scrapers

• Variable speed of the Mixer through inverter TURBINE

• Homogenizing turbine - rotor/stator typeat the bottom of the vessel or external

• Variable speed of the turbine through inverter

RANGE

300-5000 litres

VESSEL UNLOADING

• Piston valve for the product unloading, placed at the bottom of the vessel

SUPPORTING STRUCTURE

• AISI 304 stainless steel supporting structure with anti-vibration/self-levelling and adjustable support feet

OPERATOR PANEL

• Touch screen 12’’ operator panel with Siemens PLC

• Digital visualization of the process parameters

• Function for the continuous recording of process parameters: trends and datalogger (D-SCRIBA)

• CFR Part 11, Active Directory and validation package (optional)

ATEX CONFIGURATION

• ATEX certification for internal Zone 1 with nitrogen inertization and external Zone 2 (optional).

Vacuum overpressure PHARMA-FIX | FIXED LID & VESSEL

Vacuum turboemulsifiers suitable for processing liquid and creamy products.

VESSEL

• Fixed vessel with fixed lid

• Parts in direct contact with product in AISI 316 stainless steel

DUAL TECHNOLOGY

• Either internal or external recirculation or a combination of both TEMPERATURE MANAGEMENT

• Vessel with double jacket filled with water/thermic fluids for heating and cooling

• Smart temperature control system (patented) for temperature curve design

• Possibility to connect thermoregulation unit (optional)

VACUUM

• Vacuum circuit with visual passage and liquid ring pump EQUIPMENT OF THE VESSEL

• Funnel on the lid for auxiliary substances loading

• Sight-port equipped with glass-wiper and light-port with momentary light on the lid

• Tri-clamp connections and diaphragm valves on lid

MIXER

• Bi-planetary or slow coaxial mixing system (counter-rotating)

• Mixing blade with optimized profile for the vertical movement of product, including PTFE scrapers

• Variable speed of the Mixer through inverter

TURBINE

• Homogenizing turbine - rotor/stator typeat the bottom of the vessel or external

• Variable speed of the turbine through inverter

RANGE

25-10000 litres

VESSEL UNLOADING

• Piston valve for the product unloading, placed at the bottom of the vessel

SUPPORTING STRUCTURE

• AISI 304 stainless steel supporting structure with anti-vibration/self-levelling and adjustable support feet

OPERATOR PANEL

• Touch screen 12’’ operator panel with Siemens PLC

• Digital visualization of the process parameters

• Function for the continuous recording of process parameters: trends and datalogger (D-SCRIBA)

• CFR Part 11, Active Directory and validation package (optional)

ATEX CONFIGURATION

• ATEX certification for internal Zone 1 with nitrogen inertization and external Zone 2 (optional).

Vacuum

Atmospheric pressure

MIXER & MELTER

Melters and mixers originally designed as machines for the oil phase preparation, when equipped with an adequate mixing system or turbine are turned into real units for products that do not require vacuum and pressure processing.

VESSEL

• Vessel with parts in direct contact with product in AISI 316L stainless steel

• Vessel with double jacket filled with water/thermic fluids (or single wall)

• Lid in two parts with one openable side

TEMPERATURE MANAGEMENT

• Thermoregulation of the product MIXER

• Vessel can be equipped with slow mixer anchor-shaped, fast mixer helix+cowless and/or turbine on the bottom

VESSEL UNLOADING

• Inclined bottom with a side-discharging valve

• Conical bottom with central discharging valve (optional)

STRUCTURE AND OPERATOR PANEL

• Supporting frame on wheels or on feet.

• Control panel Siemens fixed to the frame

• Batch management, CFR Part 11, Active Directory and validation package (optional)

Turnkey solutions

We control every aspect of the design and production of our products, helping our customers to choose the solution best suited to their needs.

We can provide you a complete laboratory for the production of cosmetic products, optimizing space, consumption and production costs.

WE MEET YOUR NEEDS

We realize platforms with access ladders and pallets loading/unloading bays, completely made of stainless steel AISI 304, that can support vacuum turboemulsifiers, mixers and melters through a single control panel that can control all the units. We can supply steam generators, chiller units and piping for connecting the utilities to the machineries and provide a complete turnkey solution to our customers.

Cleaning systems

SEMI-AUTOMATIC CIP

Standalone or integrated system to manage the machine washing in a semiautomatic mode by setting an easy CIP program.

• High pressure recirculation pump

• Automatic valves for water recirculation or discharge

• Flexible pipe to connect mixer discharge with pump inlet

• 300 lt. stainless steel tank with detergents manual addition (optional)

• Conductivity sensor (optional)

Cleaning systems FULLY AUTOMATIC CIP

Standalone fully automatic CIP fixed system to manage the washing in a fully automatic mode.

• Main skid to be located in technical room

• Up to n°3 dosing pumps for detergents

• Up to n°2 water storage vessels with self-cleaning

• Steam or hot water exchanger for water heating

• Sanitization, sterilization and drying modules (optional)

• Possibility to execute riboflavin test on Dumek equipment (optional)

Tablet pressing CPR-6 SE

Bench top tablet press machine for small batches, designed for pharmacies, hospitals, universities and also R&Ds, in a word everywhere a small batch is needed.

• Solution for formulation development phase

• Medium and high containment (isolator) solution

• Standard punches type B or D

• Dedicated software for supporting analysis of the data

Tablet pressing CPR-18 SE

A bench top rotary tablet press machine for R&D applications, clinical testing and small production batches (laboratory batches).

• Three different turrets available

• Medium and high containment (isolator) solutions

• Flexible and compact solution

• Dedicated software for supporting analysis of the data

Tablet pressing CPR-22

Ideal for pharmaceutical and nutraceutical industries.

• Three different turrets available

• Solution for medium production batches

• Dedicated software for supporting analysis of the data

• Medium and high containment (isolator) solution

• 3 different discharge chute available (production, sampling, discarded, )

• Solution for nutraceutical products

Tablet press

HIGH CONTAINMENT SOLUTION

Rotary tablet press machine for R&D applications, clinical testing and small production batches. Digital parameter regulation enhances its efficiency and accuracy.

• Three different turrets available

• Medium and high containment (isolator) solutions

• Max Compression force 60 kN

• Standard punches type euro B or D / TSM

• Dedicated software for supporting analysis of the data

• DUST TIGHT and IP 55 version also available

The technical specifications given in this catalogue are subject to change without prior notice or liability.

Size range may vary in accordance with the different applications.

The Marchesini Group constantly updates its products to meet market needs.

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