TEST OWLIVER:
Results report Sample internal code: External reference: Sample type: Sample collection date:
Physician Name: Hospital: Report issue date:
Patient Data BMI:
ALT:
AST:
MASLD evaluation - TEST RESULT
Clinical laboratory authorized by the Basque Government: Registration No.: 48 C.2.5.6.3. 11258
Based on the lipidomic analysis and the clinical data provided, the analysis of the OWLiver® Test has determined the following result, which should be evaluated by your doctor:
MASH
No MASLD
Early-stage Steatosis
Steatosis
Late-stage Steatosis
MASH
MASH F≥2
Graphical representation of the test result. This represents the patient's liver state as No MASLD or specifies the MASLD stage of the patient.
The analysis is based on the results obtained from three algorithms expressed on a probability scale of 0 to 1. In case any of the algorithms has a positive score, an asterisk (*) will appear to its right:
ALGORITHM
PATIENT SCORE
OWLiver® MASLD MASEF® at-risk MASH OWLiver® MASH
0.997 0.326 1
* *
CUTOFF 0.50 0.33 0.50
Chart 1: Score of the algorithms comprising the OWLiver® Test - OWLiver® MASLD algorithm: differentiates between non fatty liver and MASLD. A score ≥ 0.5 means MASLD. - MASEF® at-risk MASH algorithm: among patients with MASLD, identifies those with MASH and fibrosis ≥ 2. A score ≥ 0.33 means MASH with fibrosis grade 2 or higher (at-risk MASH). - OWLiver® MASH algorithm: among patients with MASLD, discriminates between steatosis and MASH. A score ≥ 0.5 means MASH. 1
The test has been developed with samples with a BMI greater than or equal to 25 kg/m2.
Notes: MASLD: Metabolic dysfunction-Associated Steatotic Liver Disease. MASH: Metabolic dysfunction-Associated Steatohepatitis. MASH F ≥ 2: Metabolic dysfunction-Associated Steatohepatitis with fibrosis grade 2 or higher, at-risk MASH. The serum sample shall be kept for three months for such checks as may be deemed appropriate. After this time the sample will be destroyed.
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