Volume 46
Issue 2, 2022
ISSX President’s Message By Scott Obach, ISSX President Greetings Fellow ISSX Members! It’s exciting times as our organization works its way into the new normal of the changes caused by the COVID-19 pandemic. Our first in-person meeting since 2019, in Seattle this September 11–14, is imminent. Registrations continue and we are on pace to have over 500 par ticipants. It has been three long, years and I really look for ward to meeting people again (in true reality, not vir tual reality!) and having robust scientific discussions at the poster presentations and exhibits. In addition to the lectures and posters, we will have four awards given at the meeting. The award for Scientific Achievement from an Underrepresented Nation will be given for the first time. This award was established in our effor t to increase the global diversity and outreach of ISSX and is given with the appreciation that conducting
xenobiotic research can be even more challenging in nations where public funding of research is scant, and scientific and technological infrastructure may not be as advanced. We seek to honor the effor ts of our colleagues who achieve scientific advances under these circumstances. Our inaugural award honors Professor Nancy Hakooz of the University of Jordan. The R. T. Williams Distinguished Scientific Achievement Award, which is given only ever y third year at an international conference, will also be awarded in Seattle to one of our colleagues who has had a lifelong career of high accomplishments in xenobiotic research, Professor Magnus Ingelman-Sundberg of the Karolinska Institute. We will also present the Frederick J. Di Carlo to a long-time ISSX member with a long histor y of ser vice to the Society, Dr. Bill J. Smith. We round out the awards presentations with the Distinguished Accomplishments in Drug Discover y and Development
Award which is to be presented to Dr. Dennis A. Smith. The meeting will kick off with a discussion of clearance concepts led Scott Obach by Sandy Pang ISSX President and Les Benet. Clearance concepts have been with us for over 50 years and are a routinely-applied framework of xenobiotic disposition in drug research and clinical pharmacology, yet as scientists, it is always good to reexamine and reconsider even the most tried and true concepts, and I look for ward to the exchange. Beyond the Seattle meeting, planning is well under way for 2023 with three regional conferences. For the first time, ISSX will meet in India for the Asia-Pacific regional Continued on page 8
IN THIS ISSUE 2 3 6 7
Book Review Save the Date: ISSX/MDO 2022 Physiologically-based Pharmacokinetic (PBPK) Modeling ISSX Learning Center
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ISSX Focus Groups Enroll in the Mid-Year ISSX Mentorship Program Welcome New Members Renew Your ISSX Membership for 2022