International Research Journal of Engineering and Technology (IRJET)
e-ISSN: 2395-0056
Volume: 13 Issue: 01 | Jan 2026
p-ISSN: 2395-0072
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COMPARATIVE ANALYSIS OF IN VITRO ANTI-BACTERIAL ACTIVITY (BACILLUS CEREUS AND ESCHERICHIA COLI) OF ABUTILON INDICUM LEAF EXTRACTS WITH AMOXICILLIN CAPSULE M. Kavitha1, B. Gokul2, G. Gopika3, M. Gowtham4 1 Assistant Professor, Sri Vijay Vidyalaya College of Pharmacy, Dharmapuri, Tamil Nadu (India)
2, 3, 4 B. Pharm Students, Sri Vijay Vidyalaya College of Pharmacy, Dharmapuri, Tamil Nadu (India)
-----------------------------------------------------------------------***-------------------------------------------------------------------------Abstract- The aim of the study is a comparative analysis of in vitro antibacterial activity (Bacillus cereus and Escherichia coli) of Abutilon indicum (L.) Sweet leaf extracts with amoxicillin capsules. Method: Fresh leaves of Abutilon indicum (L.) Sweet were collected, shade dried, and coarsely powdered. The powdered plant material was subjected to the cold maceration extraction method using ethanol and acetone as solvents. The further extract was determined by preliminary phytochemical and comparative in vitro antibacterial activity. Conclusion: The Abutilon indicum (L.) Sweet shows antibacterial activity against pathogenic microorganisms like Bacillus cereus and Escherichia coli. The given ethanol shows good antibacterial activity against Bacillus cereus and Escherichia coli compared with the acetone extract. Key words: Abutilon indicum (L.) Sweet Leaf, Antibacterial Activity, Amoxicillin Capsule.
I. INTRODUCTION Abutilon indicum (L.) Sweet, belonging to the family Malvaceae, is a medicinal plant traditionally used for the treatment of fever, wounds, inflammation, and microbial infections [1]. Phytochemical investigations of A. indicum leaves have revealed the presence of bioactive constituents such as flavonoids, phenolic compounds, tannins, alkaloids, and saponins, which are known to contribute to its antimicrobial potential [2]. Several experimental studies have demonstrated that leaf extracts of Abutilon indicum exhibit significant antibacterial activity against both Gram-positive and Gram-negative bacteria, including Escherichia coli and Bacillus species [1,3]. The antibacterial efficacy of A. indicum has been reported to vary depending on the type of solvent used for extraction, as solvent polarity influences the extraction of active phytochemicals [3,4].
Fig: 01 Abutilon Indicum Taxonomical classification: Taxonomy: Abutilon indicium Kingdom: Plantae Division: Magno liophyta
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