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MCED Clinical Tools in Action

Page 1

DID YOU KNOW?

Only

of cancers are % detected by a preventive screening test.

25

70

% of Americans are not up to date on at least 1 preventive cancer screening.a

United States Preventive Services Task Force (USPSTF) Screening Guidelines CANCER Breast Cervical

SCREENING

CRITERIA

Biennial screening mammography

Women aged 40-74 years

• Cervical cytology every 3 years

Women aged 21-29 years

YEAR PUBLISHED 2024

• Cervical cytology every 3 years OR • High-risk human papillomavirus (hrHPV) every 5 years OR

2018; update in progress

Women aged 30-65 years

• hrHPV + cervical cytology every 5 years • Stool-based testing » Annual fecal immunochemical test (FIT) or highsensitivity guaiac-based testing » sDNA-FIT (stool DNA test with FIT) every 1 to 3 years

Colorectal

• Colonoscopy every 10 years • Computed tomography colonography every 5 years

• Age 45-75 years

2021

• Certain populations aged 76-85 years

• Flexible sigmoidoscopy » Every 5 years » Every 10 years + annual FIT

Lung Prostate

Annual low-dose computed tomography (LDCT)

Age 50-80 years and ≥20 pack per year history of smoking and currently smoke or quit within the past 15 years

2021

Prostate-specific antigen (PSA) testing

Men aged 55-69 years when elected with shared decision-making

2018; update in progress

Eligibility for MCED Screening WHO IS ELIGIBLE

RISK FACTORS

WHO IS NOT ELIGIBLE

• Age ≥50 years

• Alcohol

• Pediatric populations (<21 years)

• Family or personal history of cancer

• Exposure to cancer-causing substances (eg, fire smoke, tobacco smoke, radiation, sunlight)

• Pregnant patients

• History of childhood cancer • Known genetic mutations

• Chronic inflammation

• Patients with active cancer diagnosis or treated for cancer in last 3 years

• Diet • Hormones • Immunosuppression • Infectious agents (eg, viruses, parasites) • Overweight/obesity • Tobacco

Patient Resources Overview of MCED: www.preventcancer.org/multi-cancer-early-detection/ Frequently asked questions about MCED: www.preventcancer.org/multi-cancer-early-detection/frequently-asked-questions/ Learn more about the currently available blood-based MCED test: www.galleri.com MCED, multi-cancer early detection. a The cancer screenings included in this survey were: breast, cervical, colorectal, lung, oral, prostate, skin, and testicular cancer.


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