Improvement of chemotherapeutic protocols and algorithms of accompanying treatment made it possible to increase
the survival rate of patients with tumors of the blood system. Despite these advances, most of the cytostatic drugs currently widely
used to treat patients with hemoblastosis, in addition to the antitumor effect, also cause myelosuppression and the development
of granulocytopenia. Granulocytopenia is one of the main factors associated with infectious complications in patients with
tumors of the blood system. The nature of infectious complications may differ depending on the duration of granulocytopenia.
Keywords: agranulocytosis, immune agranulocytosis, myelotoxic agranulocytosis, acute lymphoblastic leukemias, level of
persuasion of recommendations.
