A series of novel chromene 3-aldehyde and quinoline derivatives have been synthesized using diversely substituted
nitroarenes in the presence of In, dil. HCl, H2O (reductive amination) and evaluated for in vitro cytotoxic activity in three
different cancer cell lines (MDA-MB-453, MCF-7, A549 and PC3). The synthetic strategy utilized to access these hybrids is
operationally simple and works with great substrate scope.