The purpose of this study was to prepare Pyridostigmine nanoparticles for control release of Pyridostigmine to improve
the oral bioavailability, enhance the solubility and dissolution rate by decreasing particle size of drug. Infrared spectroscopic
studies confirmed that there was no interaction between drug and polymers. The controlled release Pyridostigmine nanoparticles
were prepared by Solvent evaporation by using Ethyl cellulose, Chitosan & HPMC K100 at different ratios.