The oral microbiome is the site of the second most abundant microbiota after the gastrointestinal tract. The expanded
Human Oral Microbiome Database (eHOMD) that was last updated on November 22, 2017, contains the information of a
number of bacterial species, scientists have struggled to categorize and understand every species due to their difficulty of
laboratory study. While this much is known, the scientific community still has minimal knowledge of the entire oral microbiome
and how it may relate to potential manifestations of various diseases. Periodontitis is one disease that is directly related to the
oral microbiome.