The in-silico approach is common in today’s world. As it provide a vast knowledge of hypothetical world which have to
be proven by undergoimg in in-vitro conditions. There are much data is available on databases which helps to complete the
future study related to medicine, environment and nano-technology. The study covered the new ideas which can able to change
the approach of biosynthesis of PHB in microorganisms and degradation of biopolymer without any harmful effect on
environment as well as ecosystem.