Irreversible electroporation (IRE) is a novel and promising technique for minimally invasive ablation of solid
malignant tumours. IRE uses electric energy to cause cell death by irreversibly destabilizing cell membranes, unlike existing
thermal ablation techniques, such cryoablation and radiofrequency ablation. Over the last decade, IRE is being studied as a
promising tissue ablation tool utilizing the effect of electric field on cell membrane permeability, without harming the
surrounding normal tissue, nerves, vessels and extracellular matrices.