Schiff bases and their metal complexes plays a very important role in modern co-ordination chemistry. It possesses
novel structural features and find number of applications in various fields including food industries,dyes, agricultural ,catalysis,
polymer science. The most important feature of Schiff bases is complexation with various metals which lead to the formation of
new structures which exhibit wide range of biological activities. Transition metal complexes acts as antimicrobial, antifungal,
antiulcer, anticancer agents. This review mainly focuses on the research contributing to the preclinical screenings as well as
versatility in various fields. .