Health-related quality of life (QOL) is considered as an important component in the practices among
diabetic patients care and management; unfortunately, assessments of diabetes interventions focus mainly on self-care with
limited consideration of QOL through education and involvement of the patient. This study aimed to evaluate the effect of
self-care practice intervention on quality of life among patients with type two diabetes mellitus. Setting: The study was conducted
in the internal medicine department, internal medicine and diabetes outpatient clinic at Zagazig university hospital, Egypt.
Material and Method: a quasi-experimental study design. A purposive sample of total 240 study participants, 120 in experimental
and 120 in control group based on inclusion and exclusion criteria. Data collection questionnaire were prepared with extensive
review of previous literatures. Data collection through two tools includes, interviewing questionnaire sheet included demographic
characteristics.