Increasing global demands for the fresh water is driving research and development of advance desalination
technology. Modelling and simulation is vital for process dynamics analysis and plant initial design. The extensive range of
mathematical version for multiple effect distillation column in process industry are mentioned and model of MED is developed
that is flexible, simple to use. It’s modelled in modular technique wherein every subcomponent modelled individually and then
instantiated in order to piece collectively in complete plant version. It allows for studying various MED configurations with
minimum code duplication. The solution is to be made via the usage of equation, differential equation which simplify the coding
complexity dramatically and reduce the number of required approximation and assumptions. MATLAB is used to modelling and
simulation. This allows sensitivity to key variable associated with input, operating and design circumstance.