: The reaction of different aromatic aldehydes, ethyl acetoacetate or acetyl acetone, urea or thiourea (Biginelli reaction)
has been performed over organic white clay as the catalyst, under solvent-free conditions using microwave as the energy source,
obtaining the corresponding 3, 4- dihydropyrimidones. Powder XRD and SEM-EDX analysis was carried out to characterize the
white clay. Cystallite size of clay calculated from XRD spectra. This new method has the advantage of moderate to excellent
yields (90-95%). The advantages of this novel protocol include the excellent yield, operational simplicity, short time, and the ecofriendly preparations and the avoidance of the use of organic solvents.
