Inflammation is the symptoms of many diseases like rheumatoid arthritis and osteoarthritis. It is the cause of pain in
joints, swelling and stiffness. Various analgesic and Non Steroidal Anti- inflammatory Drugs (NSAID) such as aspirin,
diclofenac, ibuprofen etc. this may leads to severe side effects. Therefore the present study was aim to formulate herbal cream to
treat arthritis. The herbal cream contains methanol extract of Vitex negundo and Solanum trilobatum and mucilage of
Abelmoschus esculentus. Various samples were extracted and phytochemicals were qualitatively analyzed. Antibacterial activity
from the tested plants can be useful in warding of infectious diseases against human pathogens (Staphyllococcus aureus). The
presences of different bioactive compounds in plants are responsible for the antibacterial activity. The formulation of cream was
prepared by two phases oily phase and aqueous phase.
