DISINFECTANTS & CLEANING SUPPLIES
DISINFECTANTS & CLEANING SUPPLIES
Always refer to site specific SOP’s for cleaning and disinfection instructions. Guide To Frequency Cleaning. The How & When of it. Room Type/Surface
Minimum Frequency*
Method Application
Product
• Beginning of each shift
Wipe
Cleaning/Disinfecting
Step 1. Quaternary Ammonium Step 2. 70% Isopropyl Alcohol or 70% Isopropyl Alcohol wipe
• Before each batch • Every 30 minutes during compounding • When spills occur • When surface contamination is known/suspected
Wipe
Disinfecting
70% Isopropyl Alcohol or 70% Isopropyl Alcohol wipe
• Monthly or quarterly based in response to EM micro monitoring results
Wipe
Cleaning/Sporicidal
Step 1. Residue Remover & Cleaner spray or wipe Step 2. Sporicidal or 5.25% Sodium Hypochlorite or 0.52% Sodium Hypochlorite or 6% Hydrogen Peroxide spray or wipe
• During use as required
Wipe
Cleaning
70% Isopropyl Alcohol
• Daily
Wipe
Cleaning/Disinfecting
Quaternary Ammonium
• Daily (when no aseptic operations are processing)
Mop
Cleaning/Disinfecting
Quaternary Ammonium
• Monthly or quarterly based in response to EM micro monitoring results
Mop
Cleaning/Sporicidal
Step 1. Residue Remover & Cleaner spray or wipe Step 2. Sporicidal or 5.25% Sodium Hypochlorite or 0.52% Sodium Hypochlorite or 6% Hydrogen Peroxide spray or wipe
• Monthly
Mop
Cleaning/Disinfecting
Quaternary Ammonium
• Walls and Ceilings
• Monthly or quarterly based in response to EM micro monitoring results
Mop
Cleaning/Sporicidal
Step 1. Residue Remover & Cleaner spray or wipe Step 2. Sporicidal or 5.25% Sodium Hypochlorite or 0.52% Sodium Hypochlorite or 6% Hydrogen Peroxide spray or wipe
• Storage Shelving
• Monthly
Wipe
Cleaning/Disinfecting
Quaternary Ammonium
• Incoming Supplies
• As needed
Wipe
Disinfecting
Step 1. Quaternary Ammonium Step 2. 70% Isopropyl Alcohol or 70% Isopropyl Alcohol wipe
Wipe
Step 1. 5.25% Sodium Hypochlorite Deactivate/Disinfecting/ Step 2. Residue Remover & Cleaner spray or wipe Rinsing Step 3. USP Purified Water or 70% Isopropyl Alcohol or 70% Isopropyl Alcohol wipe
More frequent cleaning may be required depending on conditions
ISO 5 PRIMARY ENGINEERING CONTROLS
• (LAFW) Laminar Air Flow Workstations • (BSC) Biological Safety Cabinet • (CAI) Compounding Aseptic Isolator • (CACI) Compounding Aseptic Containment Isolator
ISO 7 & 8 BUFFER AND ANTEROOM • Counters • Work surfaces • Door plates • Handles • Gowning benches
• Floors
CHEMO COMPOUNDING • Deactivate Chemo Drugs
550
• As needed
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