Nutrition & Health READLINE Active ingredients and application solutions
From making to using, from beauty to health
Product Catalogue Green Active Ingredient Leader
Nutrition & Healthcare Ingredients Product name Chemical name
Efficacy
Content Patent
GRAS
Level of Use
ReBiohub®NMN β-Nicotinamide mononucleotide
Increases NAD+, improves sleep quality, enhances immunity, improves vitality and exercise performance
≥99%
ReBiohub®NAD+ Nicotinamide adenine dinucleotide
Improves vitality and exercise performance
≥97%
ReBiohub®GPO Collegan tripepetide (Gly-Pro-Hyp)
Oral beauty and skincare, improves joint health
≥95%
√
20–200 mg/day
ReBiohub®GSH Glutathione
Anti-oxidant, oral beauty and skincare, protects liver
≥98%
√
250–1000mg/day
ReBiohub®EGT Ergothioneine
Anti-oxidant, oral beauty and skincare, improves sleep quality and neural health
≥99%
√
√
20–50 mg/day
ReBiohub®3SL Supports probiotics, enhances intestine barrier, 3'-Sialyllactose sodium maintains gut health, skin and joint care salt
≥90%
√
√
200–1000 mg/day
ReBiohub®6SL Supports probiotics, enhances intestine barrier, 6'-Sialyllactose sodium maintains gut health salt
≥90%
√
√
200–1000 mg/day
ReBiohub®SA Promotes brain development, enhances intestine N-Acetylneuraminic acid barrier (Sialic acid)
≥98%
√
50–500 mg/day
ReBiohub®CS Carnosine
Anti-glycation, anti-oxidant, improves muscle recovery after excercise
≥99%
√
250–1000 mg/day
ReBiohub®SAC S-allyl-L-cysteine
Anti-oxidant, protects neural and cardiovascular health
≥95%
√
1–10 mg/day
ReBiohub®NRCl Nicotinamide riboside chloride
Increases NAD+, improves sleep quality, enhances immunity, improves vitality
≥98%
ReBiohub®SAL Salidroside
Anti-oxidant, anti-fatigue, protects neural and cardiovascular health
≥98%
ReBiohub®NADH Nicotinamide adenine dinucleotide, reduced disodium salt
Increases NAD+, and improves vitality
≥95%
10–20 mg/day
ReBiohub®Q10 Coenzyme Q10
Anti-oxidant, and maintains cardiovascular health
≥98%
100–300 mg/day
Anti-aging, and improves exercise performance
≥98%
500–1000 mg/day
ReBiohub®AKG α-Ketoglutarate
√
√
200–500 mg/day
300–1000 mg/day
250–1000 mg/day
√
10–50 mg/day
Version 4.2, 2026/5
The information presented on this page is intended for research reference only. Without prior written consent, information on this page cannot be copied, reproduced, or quoted. The information herein is derived from research conducted by Readline or based on publicly available literature or information. Readline makes no representations or warranties of any kind regarding its accuracy or completeness. Readers should not rely on the information on this page as a substitute for their own independent judgment and shall bear any risks arising from the use of such information.2Copyright © 2026 by Shenzhen Readline Biotech. All rights reserved. Shenzhen Readline Biotech. Email: sales@szreadline.com
F6, Bldg. B, Wanhe Pharmacy Park, No.8 Gaoxin C. Ave 1st.Shenzhen, Guangdong Tel: 0755-2665 9310
Website: www.szreadline.com
Reduced Glutathione (GSH) Liver protection | Detoxification | Boosts immunity | Skin whitening
Reduced Glutathione (GSH) L-Glutathione Reduced
CAS
Molecular Weight
Molecular Formula
Appearance
70-18-8
307.3
C10H17N3O6S
White to off-white crystalline powder
Structure O
O
HO
Product Information
N H
NH2
SH H N
O OH
O
Reduced glutathione is a natural tripeptide composed of glutamic acid, cysteine and glycine. This ingredient is present in human cells and plays a crucial role in metabolic regulation. The reduced glutathione is known for its ability to activate multiple enzymes and promote the metabolism of carbohydrates, fats and proteins. Its detoxification, anti-oxidation and immune enhancing effects are widely recognized and utilized in a variety of healthcare products.
0.4 0.3
*
0.2
* *
Red blood cell
*
*
*
0.1
1 month
0.0 -0.1
3 months 6 months
GSH (250 mg/d)
GSH (1000 mg/d)
Placebo
GSH level (mmol g-1 Hb)
GSH level (μmol mL-1)
Oral intake of GSH can effectively increase the level of GSH in blood Blood
4.0
*
3.0
*
*
*
2.0 1.0
1 month
0.0 -1.0
3 months 6 months
GSH (250 mg/d)
GSH (1000 mg/d)
Placebo
Mechanism Hepatic stellate cells
GSH
Liver cells
ROS
GSH
GSH
ROS
ROS
AMPK
MDA / HNE
Hepatic macrophages
ROS Tyrosine Tyrosinase
NF-kB
PPAR-α
Melanosomes GSH
GSH
Dopaquinone SREBP-1
Lipin-1
ECM
IL-8
Oxidation of fatty acids
Dysregulation of lipidhomeostasis
Liver fibrosis
ROS can cause tissue fibrosis by accelerating abnormal proliferation of malondialdehyde (MDA) and 4-hydroxynonenal (HNE). GSH can prevent tissue fibrosis by eliminating ROS.
IL-6
TNF-α
Glutathione dopa
Eumelanin
Pheomelanin
Brown spots, dark Tyrosinase spots
Inflammation
ROS will affect lipid homeostasis regulation, block fatty acid oxidation, and cause lipid peroxidation. GSH can prevent lipid peroxidation by eliminating ROS.
Dopachrome
ROS can stimulate the production of inflammatory factors, leading to inflammation. GSH can achieve an anti-inflammatory effect by eliminating ROS.
ROS can activate tyrosinase, leading to the production of melanin and causing skin hyperpigmentation. GSH can brighten the skin by eliminating ROS.
Efficacy
160
Before use
50
Skin whitening After 13 weeks
40 30
80 20 40
Average melanin index
200
Boost immunity IL-6 (g mL-1)
ALT (U L-1)
Protect liver
10
0 0 month
4 months
Fifteen patients with non-alcoholic fatty liver disease were supplemented with 300 mg/day of glutathione for 4 months. A decrease in plasma alanine transaminase (ALT) level was observed after 4 months.
0
Placebo
Glutathione
Fifteen HIV-positive patients were randomly divided into two groups. One group was supplemented with glutathione (1260 mg/day). After 13 weeks, the group showed a significant decrease in inflammation factor (IL-6).
Control
GSH
Left face Right face Left forearm Right forearm Left arm
Right arm
2 0 -2 -4 -6
60 healthy people were orally administered with glutathione at a dose of 500 mg/day. After 4 weeks, the average melanin index of 6 parts is significantly decreased compared with the control group. PMC-DY-YYJK-0013-151-202304-v1.0-EN
ABOUT US READLINE is a bio-tech company focusing on developing and manufacturing active ingredients for cosmetics, nutritional supplements and pharmaceuticals in a green and sustainable manner. We are driven by a shared value to enable customer success with high quality green active ingredients, from making to using, from health to beauty. Copyright © 2023 by Shenzhen Readline Biotech. Co. Ltd. All rights reserved.
CONTACT US www.szreadline.com +86 755 2665 9310 sales@szreadline.com
This product information and all further technical advice are based on our present knowledge and experience. We reserve the right to make any changes according to technological progress or further developments. No warranty or guarantee of product properties in the legal sense is intended or implied. The customer is not released from the obligation to conduct careful inspection and testing of incoming goods. Performance of the product described herein should be verified and tested by qualified experts in the sole responsibility of a customer. This product information is not intended to provide legal or regulatory advice about product uses or claims in any jurisdiction and should not be relied upon for such guidance.
NAD+ (Nicotinamide Adenine Dinucleotide) Provides energy | Boosts immunity | Anti-aging
NAD+ Nicotinamide Adenine Dinucleotide CAS
Molecular Weight
Molecular Formula
Appearance
53-84-9
663.43
C21H27N7O14P2
White to off-white powder
Structure
Product Information NAD+ (Nicotinamide Adenine Dincleotide) is an essential coenzyme found in all living cells, playing a critical role in energy metabolism, DNA repair, and cellular signaling. As a key regulator of mitochondrial function and sirtuin activation, NAD+ levels naturally decline with age, contributing to metabolic dysfunction, reduced cellular resilience, and accelerated aging. Studies have shown that NAD supplementation provides multiple benefits to the body, including boosting energy metabolism, slowing aging, improving cognitive function, enhancing muscle function, and reducing inflammation.
Mechanism NAD+ boosts ATP by shuttling electrons in mitochondria. It grabs electrons from broken-down nutrients (as NADH) and feeds them into the energy chain, powering tiny pumps that make ATP. This keeps the cellular batteries fully charged. NAD+ acts like the body’s "energy manager": ✓ Charges cells (increases ATP) ✓ Maintains power stations (protects mitochondria) ✓ Calms firestorms (fights inflammation)
Efficacy NAD+ can promote ATP production
NAD+ can inhibit inflammatory factors TNF-α concentration (ng/mL)
ATP Content (μM)
8 7 6 5 4 Control
H H2O2 2O2
120 80 40 0
100 ppm-NAD+
Experiment conditions: Control: Cell culture medium; Model group: H2O2; Test group: 100 ppm NAD+ Result: 100 ppm NAD+ can promote ATP production by 19%.
160
Control
Experiment conditions: Control: Cell culture medium; Negative control: H2O2; Test group: 10 ppm NAD+ Result: 10 ppm NAD+ has a restorative effect on mitochondrial damage.
LPS
DEX
100 ppm-NAD+
Experiment conditions: Cell: RAW264.7; Control: Cell culture medium; Negative control group: LPS; Positive control group: DEX; Test group: 100 ppm NAD+ Result: 100 ppm NAD+ has an inhibition rate of 62% on TNF-α inflammatory factor. PMC-DY-YYJK-0053-0819-202504-v1.0-EN
ABOUT US
CONTACT US
www.szreadline.com READLINE is a bio-tech company focusing on developing and manufacturing active ingredients for cosmetics, nutritional supplements and pharmaceuticals in a green and sustainable manner. We are driven by a shared value to +86 755 2665 9310 +86 755 2665 9310 enable customer success with high quality green active ingredients, from making to using, from health to beauty. sales@szreadline.com Copyright © 2025 by Shenzhen Readline Biotech. Co. Ltd. All rights reserved.
sales@szreadline.com
This product information and all further technical advice are based on our present knowledge and experience. We reserve the right to make any changes according to technological progress or further developments. No warranty or guarantee of product properties in the legal sense is intended or implied. The customer is not released from the obligation to conduct careful inspection and testing of incoming goods. Performance of the product described herein should be verified and tested by qualified experts in the sole responsibility of a customer. This product information is not intended to provide legal or regulatory advice about product uses or claims in any jurisdiction and should not be relied upon for such guidance.
ReBiohub® EGT Antioxidant | Protect mitochondria | Improve sleep and memory | Oral beauty
ReBiohub® EGT - Ergothioneine CAS 497-30-3
Molecular Weight
Molecular Formula
Appearance
229.3
C9H15N3O2S
White to off-white crystal powder
Structure
Product information Ergothioneine is a rare amino acid with potent antioxidant power, often called the “longevity vitamin”. Only certain fungi and bacteria can produce it, humans must obtain it from food. The body uses a specific transporter, ETT, to deliver ergothioneine to high-stress areas like red blood cells, aiding in antioxidant defense and repair.
Efficacy
ReBiohub® EGT ETT transporter
Clear ROS
Mitochondria H 2S Pyruvate
CSE enzyme
MPST enzyme
Activate Nrf2 Antioxidant genes
Cytoplasm
Produce H2S
Nucleus Enhanced antioxidant capacity, Reduced expression of inflammatory factors
Pervulcanizatio n modification
ROS
Mitochondrial respiration rate ETC
ATP
ROS
Targeted antioxidation
cGPDH enzyme activity
NAD+ levels
Neurotrophic support
Mitochondrial protection
Boost NAD+
Oral beauty
Research People with high plasma EGT have slower memory decline
Oral EGT prolongs stable sleep periods 52
-1.2
30
50
-1.4
20 10 0 Control
H 2O 2 H2O2
EGT
Memory z-score
40
N2 Stage
Fluorescence intensity (a.u.)
EGT protects mitochondria
48 46 44 42 40
-1.6 -1.8 -2 -2.2 -2.4
Day 0 Placebo
Day 28 EGT
0
1
2
3
Low content
4 5 Time/year High content
Result: 500 ppm ReBiohub EGT can significantly reduce mitochondrial reactive oxygen species (ROS) production
Oral take EGT 20 mg/day for 4 weeks. Result: EGT can prolong deep sleep and improve sleep quality.
470 elderly (avg. age 73) were grouped by plasma ergothioneine levels to assess memory for 5 years. Result: Higher levels linked to almost no memory decline.
Readline Efficacy Laboratory
Journal of Functional Foods, 2022, 95: 105165.
Antioxidants, 2022, 11(9): 1717.
ABOUT US
CONTACT US
www.szreadline.com READLINE is a bio-tech company focusing on developing and manufacturing active ingredients for cosmetics, nutritional supplements and pharmaceuticals in a green and sustainable manner. We are driven by a shared value to +86 755 2665 9310 +86 755 2665 9310 9310 enable customer success with high quality green active ingredients, from making to using, from health to beauty. sales@szreadline.com Copyright © 2025 by Shenzhen Readline Biotech. Co. Ltd. All rights reserved.
sales@szreadline.com sales@szreadline.com
This product information and all further technical advice are based on our present knowledge and experience. We reserve the right to make any changes according to technological progress or further developments. No warranty or guarantee of product properties in the legal sense is intended or implied. The customer is not released from the obligation to conduct careful inspection and testing of incoming goods. Performance of the product described herein should be verified and tested by qualified experts in the sole responsibility of a customer. This product information is not intended to provide legal or regulatory advice about product uses or claims in any jurisdiction and should not be relied upon for such guidance.
ReBiohub® NMN Provides energy | Improves metabolism | Anti-aging | Improves sleep | Strengthens bones
ReBiohub®NMN β-Nicotinamide Mononucleotide CAS
Molecular Weight
Molecular Formula
Appearance
1094-61-7
334.22
C11H15N2O8P
White to off-white powder
Structure
Product information NMN (β-Nicotinamide Mononucleotide) is a naturally occurring, bioactive derivative of vitamin B3 and the most direct precursor to NAD+, an essential coenzyme for cellular energy metabolism and DNA repair. As NAD+ levels decline with age, supplementing with NMN effectively boosts NAD+ in the body.
Efficacy Boost NAD+
Rebalance body clock
Strengthens bones
Delay aging
NR
Improve metabolism
NMN CD73
NAMPT
NRK NR
NMN
NADH TCA
PARP1
ETC NADH NMN
NAD+ SIRTs
NAM
NMNAT2
ART
SIRT1,2
Cytoplasm
NAD+
Nucleus
NADH
NADK
NMNAT3
NMNAT1 NAM
NAMPT
NADP NAD+
Mitochondria NADPH
PARP1
NMN SIRTs
NAM
Research
NAMPT
NMN improves insulin sensitivity 11 healthy volunteers (20-65 years old) took 250 mg NMN capsules orally every morning for 12 weeks.
NMN reduces biological age 20 healthy volunteers took 300 mg NMN daily for 60 days. Using NADRNA as a physiological age marker.
NMN can delay skin aging Air pollution particles
NMN
ROS
Activate SIRT1 Nrf2 ROS
5.6 μIU/mL
40.9 μIU/mL
36
32
Skin fibroblasts
Results: After 8 weeks, postprandial serum insulin levels increased 6 times
Results: Taking NMN for 30 days can significantly reduce biological age.
Results: NMN can improve the oxidative stress of skin cells caused by air pollution particles.
Reference: Clinical Nutrition ESPEN, 2023, 56: 83-86.
Reference: LEGEND VASCULAR SYMPOSIUM 2024
Reference: International Journal of Molecular Sciences, 2022, 23(14): 7539. PMC-DY-YYJK-0031-0819-202506-v2.0-EN
ABOUT US
CONTACT US
www.szreadline.com READLINE is a bio-tech company focusing on developing and manufacturing active ingredients for cosmetics, nutritional supplements and pharmaceuticals in a green and sustainable manner. We are driven by a shared value to +86 755 2665 9310 +86 2665 9310 9310 +86 755 755 2665 enable customer success with high quality green active ingredients, from making to using, from health to beauty. sales@szreadline.com Copyright © 2025 by Shenzhen Readline Biotech. Co. Ltd. All rights reserved.
sales@szreadline.com sales@szreadline.com
This product information and all further technical advice are based on our present knowledge and experience. We reserve the right to make any changes according to technological progress or further developments. No warranty or guarantee of product properties in the legal sense is intended or implied. The customer is not released from the obligation to conduct careful inspection and testing of incoming goods. Performance of the product described herein should be verified and tested by qualified experts in the sole responsibility of a customer. This product information is not intended to provide legal or regulatory advice about product uses or claims in any jurisdiction and should not be relied upon for such guidance.
ReBiohub SAC S-allyl-L-cysteine, natural essence derived from black garlic with systematic healthcare benefits
Antioxidant
H & V care
Brain health
ReBiohub SAC Chemical name
CAS
Formula
M. W.
Appearance
Assay
S-allyl-L-cysteine
21593-77-1
C6H11NO2S
161.22
White to off-white powder
≥95%
Introduction S-allyl-L-cysteine (SAC) is a main bioactive substance derived from fermented black garlic. It can scavenge reactive oxygen species (ROS), upregulate Nrf2 antioxidant pathway, inhibit NF-κB inflammation and reduce formation of advanced glycation end products (AGEs). With 95% oral bioavailability, SAC can be rapidly absorbed by gastrointestinal tract to deliver systemic healthcare benefits. SAC is widely recognized for its safety and application as a food flavor additive. Black garlic extracts contain merely 0.5% SAC. Readline’s proprietary synthesis technology enables mass production of pure SAC (≥ 95%), supplying consistent high-grade SAC for nutritional sectors. Alliinase
AGE
O2 Alliin
Allicin
ROS
S-allyl-L-cysteine
NF-κB Nrf2
Gastric protection
Joint health
Liver protection
•
Upregulate protective proteins
•
Boost GPX4 expression
•
Clear oxidants, protect hepatocytes
•
Strengthen antioxidant capacity
•
Reduce cartilage oxidation
•
Activate JAK2 pathway
•
Slow mucosal aging and damage
•
Reduce cartilage defects & osteophytes
•
Boost healthy liver cell regeneration
Brain health
Uric acid regulation
Heart & Vascular care
•
Clear oxidants, ease ER stress
•
Inhibit xanthine oxidase
•
Reduce triglycerides & cholesterol
•
Reduce axonal lipid oxidation
•
Scavenge ROS and reduce oxidative stress •
Stabilize BP, protect endothelium
•
Improve sleep, maintain cognition
•
Relieve hyperuricemia-related symptons
Improve insulin & fasting glucose
•
Referencs: Z. Qian et al., Cancer Discov., 2026, 16, 1341–1359; Y. Kodera et al., J. Agric. Food Chem., 2002, 50, 622–632; P. Maldonado et al., J. Phys. Chem. B, 2011, 115, 13408–13417; M. S. Ahmad et al., Eur. J. Pharmacol., 2007, 561, 32–38; Y. J. Choi et al., Gut & Liver, 2016, 10, 348–355; Y. J. Choi et al., Gut & Liver, 2016, 10, 749–756; M. Nakamoto et al., Exp. Ther. Med., 2025, 29, 102; S. Nirvanashetty et al., Open Acc. J. Comp. & Alt. Med., 2023, 5, MS.ID.000202
Application info +86 755 2665 9310
Global approval SAC is approved as a synthetic flavor in food additive inventory worldwide, including:
Benefits Dosage
China
S1157
US
FEMA No. 4322
EU
FL-no. 17.036
WHO
JECFA 1710
Formulation suggestion
About us
Antioxidant, gastric protection, joint care, brain health, H & V care, uric acid regulation sales@szreadline.com 1–10 mg/day GPO, 3’-SL, GSH, NMN, etc.
Contact us
READLINE is a biotech company focusing on developing and manufacturing active ingredients for cosmetics, nutritional supplements and pharmaceuticals in a green and sustainable manner. We are driven by a shared value to enable customer success with high quality green active ingredients, from making to using, from health to beauty.
www.szreadline.com
Copyright © 2026 by Shenzhen Readline Biotech. All rights reserved.
+86 0755 2665 9310
The product information presented on this page is intended for research reference only. Without prior written consent, no part of this page may be copied, reproduced, or quoted by any party. The information herein is derived from research conducted by Readline or based on publicly available literature or information. The company makes no representations or warranties of any kind regarding its accuracy or completeness. Readers should not rely on the information on this page as a substitute for their own independent judgment and shall bear any risks arising from the use of such information.
sales@szreadline.com
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