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Sources,ix
Abbreviations,xi
DrugCalculationFormulae,xv
SECTIONI:CriticalCareIntravenousInfusionDrugs— QuickMixingGuide,1
QuickReferenceInfusionDrugCompatibilityand IncompatibilityChart,9
SECTIONII:IntravenousInfusionDrugs,53
Abciximab(ReoPro),54
Alteplase(Activase),59
Aminophylline(Theophylline),63
Amiodarone(Cordarone),67
Argatroban(Acova),73
Atracurium(Tracrium),77
Bivalirudin(Angiomax),80
Cisatracurium(Nimbex),85
Conivaptan(Vaprisol),89
Dexmedetomidine(Precedex),92
Diltiazem(Cardizem),95
Dobutamine(Dobutrex),99
Dopamine(Intropin),107
DrotrecoginAlfa(Xigris),115
Epinephrine(Adrenalin)Injection,123
Eptifibatide(Integrilin),128
Esmolol(Brevibloc),133
Fenoldopam(Corlopam),136
Haloperidol(Haldol),139
Heparin,141
Ibutilide(Corvert),148
ImmuneGlobulinIntravenous(Carimune,Gamimune, Gammagard,Gammar-P,Gamunex,Iveegam, Octagam,Panglobulin,Polygam,Sandoglobulin, Venoglobulin-S),150
Inamrinone(Inocor),154
Infliximab(Remicade),161
InsulinDrip,165
Isoproterenol(Isuprel),168
Labetalol(Trandate),173
Lepirudin(Refludan),177
Lidocaine(Xylocaine),181
Lorazepam(Ativan),185
MagnesiumSulfate(MgSO4),189
Midazolam(Versed),193
Milrinone(Primacor),196
Nesiritide(Natrecor),201
Nicardipine(Cardene),204
Nitroglycerin,208
Nitroprusside(Nipride),212
Norepinephrine(Levophed),224
Octreotide(Sandostatin),232
Pantoprazole(Protonix),234
Phenylephrine(Neo-Synephrine),237
PotassiumChloride(KCl),240
Procainamide(Pronestyl),245
Propofol(Diprivan),249
Reteplase(Retavase),253
Tenecteplase(TNKase),255
TirofibanHCl(Aggrastat),258
Vasopressin(Pitressin),262
SECTIONIII:ACLSGuidelinesforAdultEmergency
CardiacCareAlgorithms,267
PulselessVentricularTachycardia(VT)/Ventricular Fibrillation(VF),268
Asystole,271
PulselessElectricalActivity(PEA),274
PulselessElectricalActivity(PEA):ClinicalSignsand Treatment,277
SymptomaticBradycardia,283
NarrowQRSTachycardia,286
AtrialFibrillation/AtrialFlutterAlgorithm,291
Wolff-Parkinson-White(WPW)SyndromeAlgorithm,296
SustainedMonomorphicVentricularTachycardia,300
PolymorphicVentricularTachycardia,304
WideQRSTachycardiaofUnknownOrigin,309
InitialAssessmentandGeneralTreatmentofthePatient withanAcuteCoronarySyndrome(ACS),313
ManagementofST-SegmentElevationMyocardial Infarction(MI),316
ManagementofUnstableAngina/Non–ST-Segment ElevationMyocardialInfarction(MI),319
ManagementofPatientwithaSuspectedAcuteCoronary SyndromeandNondiagnosticorNormalECG,321
ManagementofAcutePulmonaryEdema,322
ManagementofHypotension/Shock:SuspectedPump Problem,326
ManagementofHypotension/Shock:Suspected VolumeProblem,330
ManagementofHypotension/Shock:SuspectedRate Problem,332
Sources AehlertB: ACLSquickreviewstudyguide,ed3, StLouis,2007,Mosby.
AmericanHeartAssociation: Advancedcardiaclife supportprovidermanual,2006,AmericanHeart AssociationInc.
AmericanHeartAssociationinCollaborationwiththe InternationalLiaisonCommitteeonResuscitation (ILCOR).Part6:Advancedcardiovascularlifesupport; Section7:AlgorithmapproachtoACLSemergencies, Circulation 102(supplI):136-171,2000.
AmericanSocietyofHealthSystemPharmacists: Americanhospitalformularyservice,Bethesda,Md, 2008,TheSociety.
GahartBL,NazarenoAR: 2009intravenous medications,ed25,StLouis,2009,Mosby.
Goldberg,PA,Clinicalresultsofanupdatedinsulin infusionprotocolincriticallyillpatients, Diabetes Spectrum 18:188-191,2005.
HazinskiMF,FieldJM,GilmoreD,editors: Handbook ofemergencycardiovascularcare2008:For healthcareproviders,Dallas,2008,AmericanHeart Association.
LacyCF,ArmstrongLL,GoldmanMP,LanceLL: 2007–2008Druginformationhandbook,ed15, Cleveland,2007,Lexi-CompIncandAmerican PharmaceuticalAssociation.
LesterRM,Dente-CassidyAM: Intravenous medicationsforcriticalcare,ed2,Philadelphia,1996, Saunders.
MedicalEconomicsStaff: Physician’sdeskreference 2008,ed62,Oradell,NJ,2008,MedicalEconomics Company.
TrisselLA: Handbookofinjectabledrugs,ed15, Bethesda,Md,2009,AmericanSocietyofHealth SystemPharmacists.
Abbreviations ACS acutecoronarysyndrome
ACT activatedclottingtime
ADRs adversedrugreactions
AED automaticexternaldefibrillator
AMI acutemyocardialinfarction
aPTT activatedpartialthromboplastintime
AV atrioventricular
AVNRT atrioventricularnodalreentrytachycardia
AVRT atrioventricularreciprocatingtachycardia
BLS basiclifesupport
BP bloodpressure
CABG coronaryarterybypassgrafting
CAD coronaryarterydisease
CBC completebloodcount
CCU cardiaccareunit
CF calculationfactor
CHF congestiveheartfailure
CLL chroniclymphocyticleukemia
CNS centralnervoussystem
COPD chronicobstructivepulmonarydisease
CPR cardiopulmonaryresuscitation
CrCl creatinineclearance
CSU cardiacsurgeryunit
CVA cerebrovascularaccident,cardiovascular accident
CVP centralvenouspressure
D5W dextrose5%
DBP diastolicbloodpressure
DIC disseminatedintravascularcoagulation
DNAR DoNotAttemptResuscitation
ET endotrachealtube
GGT g-glutamyltransferase
GI gastrointestinal HIT heparin-inducedthrombocytopenia
HR heartrate
ICU intensivecareunit
IgG immunoglobulinG
IHSS idiopathichypertropicsubaorticstenosis
IM intramuscular
INR internationalnormalizedratio
IO intraosseous
ITP idiopathicthrombocytopenicpurpura
IV intravenous
IVP intravenouspyelogram
LBBB leftbundlebranchblock
LMWH lowmolecularweightheparin
MAO monamineoxidase
MAP meanarterialpressure
MAT multifocalatrialtachycardia
NG nasogastric
NPO nothingbymouth
OBS organicbrainsyndrome
PCI percutaneouscoronaryintervention
PCWP pulmonarycapillarywedgepressure
PE pulmonaryembolism
PEA pulselesselectricalactivity
PO bymouth
PRN asneeded
PSVT paroxysmalsupraventriculartachycardia
PT prothrombintime
PTCA percutaneoustransluminalcoronaryangioplasty
PTT partialthromboplastintime
PVC polyvinylchloride
RR respiratoryrate
rTPA recombinanttissueplasminogenactivator
SA sinoatrial
SaO2 saturationlevelofoxygeninhemoglobin
SBP systolicbloodpressure
SC subcutaneous
SGOT serumglutamic-oxaloacetictransaminase
SGPT serumglutamic-pyruvictransaminase
TEE transesophagealechocardiography
TNF-a humantumornecrosisfactoralpha
TPA tissueplasminogenactivator
TPN totalparenteralnutrition
USP UnitedStatesPharmacopeia
VF ventricularfibrillation
VT ventriculartachycardia
WPW Wolff-Parkinson-White
Thispageintentionallyleftblank
DrugCalculationFormulae DrugCalculationFormulae 1.Calculateconcentrationofanydruginabag(orbottle).
Amountofdruginbag ðmgÞ
Totalvolumeofthebag ðmLÞ ¼ Concentrationinmg=mL
Example:
Nitroglycerin25mg D5W250mL ¼ 0:1mg=mL ¼ 100mcg=mL
2.Calculatedoseadministeredforagiveninfusionrate.
Concentrationinbag ðmg=mLÞ infusionrate 60min ¼ Doseperminute
Example: Procainamide4mg/mLisinfusingat30mL/hr.Whatdoseisinfusing(mg/min)?
Procainamide4mg=mL 30mL=hr 60mg ¼ 2mg=min
3.Calculateinfusionrateforagivendoseinmcg/kg/min.
Bodyweight ðkgÞ Dose ðmcg=kg=minÞ
Drugconcentration ðmcg=mLÞ ¼ InfusionrateinmL=min 60min=hr ¼ Rate ðmL=hrÞ
Example: Dobutamine5mcg/kg/minfora60-kgpatient.
60kg 5mcg=kg=min
2000mcg=mLbag ¼ 0:15mL=min 60min=hr ¼ 9mL=hr
4.Calculationfactors(CF).
Dose ðmcg=kg=minÞ
Infusionrate ðmL=hrÞ ¼ CF
Example: Dobutamineat5mcg/kg/minina60-kgpatientisinfusingat9mL/hr.
5mcg=kg=min
9mL=hr ¼ 0:556CF
Calculationfactorscanbeusedtoquicklyconvertaparticulardoseofadrugorinfusiontoaspecificinfusionrate inmL/hrorviceversa.Thiscanbehelpfulwhentitratingvariousdrugstoeffect,andfrequentchangesininfusion ratemayneedtobeconvertedtotheactualdoseofdrugadministered.Forexample,ifweneededtochangethe infusionratefrom9mL/hrofdobutamineto15mL/hrtomaintainbloodpressure,howmanymcg/kg/minwould beinfusing?MultiplytheCFbythenewratetogetthenewdose,or0.556 15=8.34mcg/kg/min.
DrugCalculationFormulae DrugCalculationFormulae—cont’d COMMONMETRICCONVERSIONS 1000micrograms(mcg)=1milligram(mg)
1000milligrams(mg)=1gram(g)
1000grams(g)=1kilogram(kg)
1milliliter(mL)=1cubiccentimeter(cc)
1000milliliters(mL)=1liter(L)
CriticalCareIntravenousInfusionDrugs— QuickMixingGuide CriticalCareIntravenousInfusionDrugs—QuickMixingGuide ABCIXIMAB(REOPRO) Bolusdose: GivenIVpush
Maintenancedose: Addrequiredmaintenancedose to 250 mLD5W
ALTEPLASE(ACTIVASE) Add100mgalteplaseto100mLsterilewateror 50mgalteplaseto50mLsterilewater
Finalconcentration: 1mg/mL
AMINOPHYLLINE(THEOPHYLLINE) 500MGIN500MLD5W
Premadesolution: Theophylline400mg/500mLor 800mg/1000 mL
Finalconcentration: 1mg/mLofaminophylline
AMIODARONE(CORDARONE)
Bolusdose: Add150mgto100mLD5W
Maintenancedose: Add900mgto500mLD5Win glassbottle
Final concentration: 1.8mg/mL
ARGATROBAN(ACOVA)250MGIN 250MLNS
Add250mg(2.5mL)argatrobanto250mLNS
Finalconcentration: 250mg/250mL(1mg/mL)
ATRACURIUM(TRACRIUM)250MG (25ML)IN250MLD5W
Add250mg(25mL)atracuriumto225mLD5W
Finalconcentration: 1mg/mL
BIVALIRUDIN(ANGIOMAX)250MG (5ML)IN50MLD5W
Add250mg(5mL)bivalirudinto50mLD5W
Finalconcentration: 5mg/mL
CISATRACURIUM(NIMBEX)250MG IN250MLD5W
Add250mg(25 5-mLvials)cisatracuriumto125mL D5W
Finalconcentration: 1mg/mL
CONIVAPTAN(VAPRISOL)
20mgIVloadingdose;20-40mg/dayIVcontinuous infusion;maximumdurationis4days
Finalconcentration: 200 mg in100mLD5W (0.2mg/mL)and40mgin250mLD5W(0.16mg/mL)
DEXMEDETOMIDINE(PRECEDEX)2MG IN50MLNS
Add2mLPrecedexto48-mLNSminibag
Finalconcentration: 4mcg/mL
DILTIAZEM(CARDIZEM)125MG IN100MLD5W
Add125mg(5 25-mgvials)diltiazemto100mL D5WorNS
Finalconcentration: 125mg/125mL(1mg/mL)
DOBUTAMINE(DOBUTREX)500MG IN250MLD5W
Premadesolution
Finalconcentration: 500mg/250mL(2mg/mL)
DOPAMINE(INTROPIN)400MG IN250MLD5W
Premadesolution
Finalconcentration: 400mg/250mL(1600mcg/mL)
DROTRECOGINALFA(XIGRIS)(2 3 5MG) 10MGIN100MLNS
Add10mg(2 5mgvials)to100mLNS
Finalconcentration: 10,000mcg/100mL(100mcg/ mL)
EPINEPHRINE(ADRENALIN)1MG IN250MLD5WORNS
Add1mg(1ampule)epinephrineto250mLD5WorNS
Finalconcentration: 1mg/250mL(4mcg/mL)
EPTIFIBATIDE(INTEGRILIN)75MG IN100-MLVIAL
Premadesolution
Bolusdose: from10-mLvial
Maintenancedose: from75-mg/100-mLvial
CriticalCareIntravenousInfusionDrugs—QuickMixingGuide ESMOLOL(BREVIBLOC)2.5GIN250ML D5WORNS
Add2.5g(10mLof250-mg/mLvial)esmololto250mL D5WorNS
Finalconcentration: 10mg/mL
FENOLDOPAM(CORLOPAM)10MG IN250MLD5WORNS
Add10mg(1mL)fenoldopamto250mLD5WorNS
Finalconcentration: 40mcg/mL
HALOPERIDOL(HALDOL)FORRAPID TRANQUILIZATION
Availableas5-mg/mLvialforIVpush
HEPARIN25,000UNITSIN500MLD5W
Premadesolution
Finalconcentration: 25,000units/500mL(50units/ mL)
IBUTILIDE(CORVERT)1MGIN50ML D5WORNS
Add1mg(10-mLvial)ibutilideto50mLD5WorNS MayalsobegivenIVpushover10minutes
IMMUNEGLOBULINDOSES Seedosingchart
INAMRINONE(INOCOR)500MG IN100MLNS
Add500mg(5 100-mgampules)inamrinoneto 100mLNS
Finalconcentration: 500mg/200mL(2.5mg/mL)
INFLIXIMAB(REMICADE)100MG TO900MGIN250MLNS
Add100mgto600mg(calculatecorrectdoseby weightindosingcharts)tototalvolumeof250mL NS
Finalconcentration: 0.4to4mg/mL
INSULIN100UNITSIN250MLNS Add100units(1mL)insulinto250mLNS
Finalconcentration: 100units/250mL(2units/5mL)
For intensive insulinprotocolsadd100(1mL)to 100mLNS
Finalconcentration: 100units/100mL(1unit/mL)
ISOPROTERENOL(ISUPREL)1MG IN250MLD5W Add1mg(1ampule)isoproterenolto250mLD5W
Finalconcentration: 1mg/250mL(4mcg/mL)
LABETALOL(TRANDATE)200MG IN200MLNS
Add200mg(40mL)labetalolto160mLNS
Finalconcentration: 200mg/200mL(1mg/mL)
LEPIRUDIN(REFLUDAN)100MG IN250MLNS
Add100mg(2mL)lepirudinto250mLNS
Finalconcentration: 0.4mg/mL
LIDOCAINE2GIN500MLD5W Premadesolution
Finalconcentration: 2g/500mL(4mg/mL)
LORAZEPAM(ATIVAN)40MGIN500ML D5W
Add40mg(10mL)lorazepamto500mLD5Win glassbottle
Finalconcentration: 0.08mg/mL
MAGNESIUMSULFATE(MGSO4) Add1gmagnesiumsulfateto50mLNSor2gto 100mLNS
Premixeddoses4%solution,4g/100mLor40g/ 1000mL(foreclampsia)
1-2g(2-4mLof50%solution)dilutedin10mLD5W maybegivenIVpushforcardiacarrest
Finalconcentration: 1 g/50 mL(20mg/mL)
CriticalCareIntravenousInfusionDrugs—QuickMixingGuide MIDAZOLAM(VERSED)125MG IN125MLNS
Add125mg(25mLof5mg/mLvials)midazolamto 100mLNS
Finalconcentration: 1.0mg/mL
MILRINONE(PRIMACOR)20MG IN100MLD5W
Premadesolution
Finalconcentration: 0.2mg/mL
NESIRITIDE(NATRECOR)1.5MG IN250MLD5W
Add1.5mg(5mL)nesiritideto250mLD5W
Finalconcentration: 1.5mg/250mL(6mcg/mL)
NICARDIPINE(CARDENE)
Add1ampule(25mg/10mL)to240mLofDextrose 5%orNSresultingin250mLofsolution
Finalconcentration: 0.1mg/mL
A premixed 200mLsolutionisalsoavailablecontaining20mginNSorD5W
Finalconcentration: 0.1mg/mL
NITROGLYCERIN25MGIN250MLD5W
Premadesolution
Finalconcentration: 25mg/250mL(100mcg/mL)
NITROPRUSSIDE(NIPRIDE)50MG IN500MLD5W
Add50mg(1vial)nitroprussideto500mLD5W
Finalconcentration: 50mg/500mL(100mcg/mL)
NOREPINEPHRINE(LEVOPHED)4MG IN250MLD5WORNSWITHREGITINE 5MG/250ML
Add4mg(1 4-mgampule)norepinephrineto 250mLD5WorNSandadd5mgRegitine (1 5–mgvial)toeach250-mLbag
Finalconcentration: norepinephrine4mg/250mL (16 mcg/mL)
OCTREOTIDE(SANDOSTATIN) 1200MCGIN250MLD5WORNS
Add1200mcg(2.4mL)Sandostatinto250mLD5W orNS
Finalconcentration: Sandostatin4.8mcg/mL
PANTOPRAZOLE(PROTONIX)40–80MG IN100MLD5WORNS
Add10mLNStoeach40-mgvialandaddcontentsto 90mLNS
Finalconcentration: 40mg/100mL(0.4mg/mL)or 80 mg/100 mL(0.8mg/mL)
PHENYLEPHRINE(NEO-SYNEPHRINE)
10MGIN250MLD5W
Add10mg(1ampule)phenylephrineto250mLD5W
Finalconcentration: 10mg/250mL(40mcg/mL)
POTASSIUMCHLORIDE(KCl)
Basedonserumpotassiumlevels:20-60mEq/dayis usual
Typicaldosesbasedonserumlevels:
3.1-3.4mmol/Lgive20mEqevery2hr 2doses
2.5-3mmol/Lgive20mEqevery2hr 3doses
Lessthan2.5mmol/Lgive20mEqevery2hr 4 doses
1.Max:200mEq/dayandrarelyupto400mEq/ daywithextremecaution.
2.Maxinfusionrate:10mEq/hr;inseverehypokalemia(K < 2.0),20-40mEq/hrwith extremecautionandinfusionpump
Finalconcentration: 10 mEq/100 mL(centralline)or 40mEq/500mL(peripheral)
PROCAINAMIDE(PRONESTYL)1G IN250MLD5WORNS
Add1g(1vial)Pronestylto250mLD5WorNS
Finalconcentration: 1g/250mL(4mg/mL)
PROPOFOL(DIPRIVAN)500MG/50ML OR1G/100MLEMULSION
Premadesolution
Finalconcentration: 10mg/mL
CriticalCareIntravenousInfusionDrugs—QuickMixingGuide RETEPLASE(RETAVASE)20-UNITKIT Add10mLsterilewaterto10unitsRetavasewithkit provided
Repeatforsecond10-unitdose
TENECTEPLASE(TNKase) Add10mLsterilewaterto50mgTNKase
Finalconcentration: 5mg/mL
TIROFIBAN(AGGRASTAT)12.5MG
IN250MLD5WORNS Apremixedsolution100mLor250mLcontainer, Finalconcentration: 50mcg/mLor0.05mg/mL
VASOPRESSIN(PITRESSINSYNTHETIC) 250UNITSIN250ML Add250units(12.5mLof20units/mL)vasopressinto 250mLD5WorNS
Finalconcentration: 250units/250mL(1unit/mL)
QuickReferenceInfusionDrugCompatibilityandIncompatibilityChart
Drug Compatibility Incompatibility
Abciximab Unknownornoinformation
Alteplase
Dextrose5%
Lidocaine
Aminophylline
Allopurinol
AmphotericinB
Bretylium
Ceftazidime
Cimetidine
Cladribine
Diltiazem
Dopamine
Doxorubicin
Enalaprilat
Esmolol
Etoposide
Famotidine
Filgrastim
Metoprolol
Propranolol
Fluconazole
Foscarnet
Gatifloxacin
Gemcitabine
Granisetron
Heparin
Inamrinone(Inocor)
Labetalol
Lidocaine
Linezolid
Meropenem
Morphine
Nitroglycerin
Paclitaxel
Unknownornoinformation
DobutamineDopamine
Amiodarone
Atracurium
Chlorpromazine (Thorazine)
Ciprofloxacin
Clindamycin
Codeine
Dobutamine
Hydralazine
Hydroxyzine (Vistaril)
Insulin
Isoproterenol
Meperidine (Demerol)
Norepinephrine
Ondansetron (Zofran)
Prochlorperazine (Compazine)
Phenytoin (Dilantin)
Promethazine (Phenergan)
Verapamil
Continued
QuickReferenceInfusionDrugCompatibilityandIncompatibilityChart—
Drug Compatibility Incompatibility
Pancuronium
Piperacillin
Potassiumchloride
Propofol
Ranitidine
Amiodarone Amikacin
Bretylium
Clindamycin
Dobutamine
Doxycycline
Erythromycin
Esmolol
Gentamicin
Insulin
Isoproterenol
Labetalol
Lidocaine
Metaraminol
Remifentanil
Sargramostim
Tacrolimus
Vecuronium
Metronidazole
Midazolam
Morphine
Nitroglycerin
Norepinephrine
PenicillinG
Phentolamine
Phenylephrine
Potassiumchloride
Procainamide
Tobramycin
Vancomycin
Aminophylline
Cefazolin
Heparin
Sodiumbicarbonate
ArgatrobanUnknownornoinformation
Atracurium Bretylium
Cefazolin
Cefuroxime
Cimetidine
Dobutamine
Dopamine
Epinephrine
Esmolol
Etomidate
Fentanyl
Gentamicin
Heparin
Hydrocortisone
Bivalirudin
Dexamethasone
Digoxin
Diphenhydramine
Dobutamine
Dopamine
Isoproterenol
Lidocaine
Lorazepam
Midazolam
Milrinone
Morphine
Nitroglycerin
Procainamide
Ranitidine
Sodium nitroprusside
Trimethoprim/sulfa
Vancomycin
Epinephrine
Eptifibatide
Esmolol
Furosemide
Heparin
Unknownornoinformation
Aminophylline
Diazepam
Propofol
Thiopental
[includingY-site]
Alteplase(tPA)
Amiodarone
hydrochloride
AmphotericinB
Chlorpromazine
hydrochloride
Diazepam
Prochlorperazine
Reteplase(rtPA)
Continued
QuickReferenceInfusionDrugCompatibilityandIncompatibilityChart—
Drug Compatibility Incompatibility
Hydrocortisone
Lidocaine
Meperidine
Methylprednisolone
Midazolam
Morphine
Cisatracurium [viaY-site]
Alfentanil
Amikacin
Aztreonam
Bretylium
Bumetanide
Buprenorphine
Butorphanol
Calciumgluconate
Ceftriaxone
Nitroglycerin
Potassiumchloride
Sodiumbicarbonate
Tirofiban
Verapamil
StreptokinaseVancomycin hydrochloride
Chlorpromazine
Cimetidine
Ciprofloxacin
Clindamycin
Dexamethasone
Digoxin
Diphenhydramine
Dobutamine
Dopamine
Doxycycline
Droperidol
Acyclovir
Aminophylline
AmphotericinB
Ampicillin
Ampicillin/ sulbactam
Cefazolin
Cefotaxime
Cefotetan
Cefoxitin
Ceftazidime
Cefuroxime
Diazepam
Diprivan
Furosemide
Ganciclovir
Heparin
Ketorolac
Methylprednisolone
Nitroprusside
Piperacillin
Thiopental
Enalaprilat
Epinephrine
Esmolol
Famotidine
Fentanyl
Fluconazole
Gatifloxacin
Gentamicin
Haloperidol
Hydrocortisone
Hydromorphone
Hydroxyzine
Imipenem/cilastatin
Inamrinone
Isoproterenol
Ketorolac
Lidocaine
Linezolid
Lorazepam
Magnesiumsulfate
Mannitol
Meperidine
Metoclopramide
Metronidazole
Midazolam
Minocycline
Morphine
Nalbuphine
Nitroglycerin
Norepinephrine
Ofloxacin
Ondansetron
Phenylephrine
Potassiumchloride
Procainamide
Prochlorperazine
Promethazine
Ranitidine
Remifentanil
Sufentanil
Ticarcillin/clavulanate
Trimethoprim/sulfa
Zosyn
