Advances in medicine causes new, groundbreaking drug by Quantum Genomics (QNNTF)
To help with chronic hypertension
The creators of Firibastat
New York, August 1st, 2019: Quantum Genomics are the creators of Firibastat, a first-in-class brain aminopeptidase inhibitor (BAPAI) that could potentially treat treatment-resistant hypertension by acting in the brain to interfere with the renin-angiotensin system.
http://www.quantum-genomics.com/
The complications associated with Hypertension
It is estimated that there are around 150 million people worldwide that are affected by treatment resistant hypertension, resulting in almost 10 million deaths per year from complications due to high blood pressure. With such a high number of people dealing with this chronic condition (around 1.1 billion people). For those with treatment resistant hypertension, they can be more susceptible to complications associated with hypertension such as heart failure, coronary artery disease, stroke, kidney disease and peripheral artery disease.
http://www.quantum-genomics.com/
Standard treatments
Standard treatments for hypertension include extensive lifestyle changes to address potential factors that may have contributed to the disease and multi-drug regimens, based on preference of the treating doctor.
http://www.quantum-genomics.com/
A NEW-HOPE
Quantum Genomics has concluded NEW-HOPE, which is phase 2b trial in difficult-to-treat hypertension. The trial included 256 overweight and obese patients with primary hypertension across the US including 53% of minorities patients (of whom 38% of AfricanAmerican) , 44% are female, and 26% are above the age of 65 years old. This kind of population is more likely to suffer from resistant hypertension.
http://www.quantum-genomics.com/
The Results of the trial
Results of the trial indicated that treatment with Firibastat for 8 weeks resulted in significant (p<0.0001) decreased office systolic blood pressure by 9.5 mmHg (from 153.9 down to 144.4 mmHg) and was determined to be safe. Firibastat’s efficiency was similar in black (-10.5mmHg) and nonblack (-8.9mmHg) populations, contrary to other anti-hypertensive classes.
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Not equally common across all demographics
Treatment-resistant hypertension is not equally common across all demographics and ethnicities and was more prevalent in black, Hispanic, elderly and female populations. Obese patients with hypertension were 5 times more likely to be resistant to treatment.
http://www.quantum-genomics.com/
A larger blood pressure decrease
The trial also showed a larger blood pressure decrease for patients with higher baseline hypertension, a predictive factor of resistant hypertension. Based on the outcome of the NEW-HOPE trial, Quantum Genomics will initiate a phase 3 pivotal trial in resistant hypertension with Firibastat. Based in Paris and New York, Quantum Genomics trades on the OTCQX in the United States (symbol: QNNTF) and Euronext Paris (symbol: ALQGC).
http://www.quantum-genomics.com/
Media Contact:
NAME :
Jean-Philippe MILON
Email:
jean-philippe.milon@quantum-genomics.com
Twitter:
https://twitter.com/QuantumGenomics
Linkedin: https://www.linkedin.com/company/quantum-genomics/ Website:
http://www.quantum-genomics.com/