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Fatty liver drug shows promise in Tulane study Treatment could clear cells that set stage for disease
BY EMILY WOODRUFF
A Jefferson Street underpass is flooded after an April storm. STAFF FILE PHOTO By BRAD BOWIE
FLOOD WATCH Unlike Texas, Lafayette’s flat topography allows warning of rising waters, but area can still learn from tragedy
BY CLAIRE TAYLOR
Staff writer
Topography is one of the main reasons it isn’t likely Lafayette will see rushing floodwaters along the Vermilion River like those that devastated parts of the Texas Hill Country over the July Fourth weekend. There just aren’t any hills in south Louisiana, and the Vermilion River basically is flat. “Our land’s a lot slower,” said Chad Sonnier, director of Lafayette’s Office of Homeland Security and Emergency Preparedness. At least 120 people are dead and about 170 are missing after heavy rainfall sent a massive wall of water, 25 to 30 feet deep, rushing through Central Texas overnight Friday into Saturday. Residents and vacationers, including children attending summer camps along the Guadalupe River, were caught off guard as, without much warning, the river rose 20 feet in under an hour in some places.
ä See FLOOD, page 4A
ASSOCIATED PRESS PHOTO By RODOLFO GONZALEZ
First responders from College Station Fire Department search Sunday along the banks of the Guadalupe River in Ingram, Texas. Flash floods can develop with little to no warning in parts of Texas with spots that are steep and rocky.
Staff writer
Fatty liver disease affects more than a third of adults in the United States, a silent epidemic closely tied to obesity and diabetes. In Louisiana, where both conditions are more common than the national average, doctors suspect the disease is even more widespread, often going undetected until it becomes life-threatening. Scientists from Tulane University are part of a multiuniversity team exploring a potential new treatment that could stop the disease before it Sometimes turns deadly. In a study published called earlier this year in Na“zombie ture Aging, the team cells,” found that a drug called senescent 753b cleared out harmful aging cells known as cells build up senescent cells. in the liver as Sometimes called people age “zombie cells,” they or develop build up in the liver as obesity and people age or develop diabetes. obesity and diabetes. The cells no longer function properly, but they don’t die off. Instead, they linger in the body, increasing inflammation and damaging nearby tissue, which sets the stage for disease. Senescent cells are a key feature of chronic liver disease, said Liya Pi, a pathologist at Tulane School of Medicine and an author of the study. The drug can clear senescent cells and reduce the development of liver disease to fibrosis and the most common type of liver cancer, she said. The disease, now called MASLD (metabolic dysfunction-associated steatotic liver disease), was previously known as nonalcoholic fatty liver disease. It rarely causes symptoms in early stages.
ä See LIVER, page 4A
Judge pauses Trump’s birthright citizenship order nationwide BY HOLLY RAMER and MIKE CATALINI birthright citizenship issue on a difference. Associated Press
ASSOCIATED PRESS FILE PHOTO By JACQUELyN MARTIN
Mairelise Robinson attends a May protest in support of birthright citizenship outside the Supreme Court in Washington.
WEATHER HIGH 90 LOW 75 PAGE 12C
CONCORD, N.H. — A federal judge in New Hampshire issued a ruling Thursday prohibiting President Donald Trump’s executive order ending birthright citizenship from taking effect anywhere in the U.S. Judge Joseph LaPlante issued a preliminary injunction blocking Trump’s order and certified a class action lawsuit including all children who will be affected. The order, which followed an hourlong hearing, included a seven-day stay to allow for appeal. The judge’s decision puts the
fast track to return to the Supreme Court. The justices could be asked to rule whether the order complies with their decision last month that limited judges’ authority to issue nationwide injunctions. The Supreme Court said district judges generally can’t issue nationwide, or universal, injunctions. But it didn’t rule out whether judges could accomplish much the same thing by a different legal means, a class action. The class approved in New Hampshire is slightly narrower than that sought by the plaintiffs, who wanted to include parents, but attorneys said that wouldn’t make a material
Business ......................6A Commentary ................3B Nation-World................2A Classified ..................10C Living............................5C Opinion ........................2B Comics-Puzzles .....7C-9C Metro ...........................1B Sports ..........................1C
“This is going to protect every single child around the country from this lawless, unconstitutional and cruel executive order,” said Cody Wofsy, an attorney for the plaintiffs. The lawsuit was filed on behalf of a pregnant woman, two parents and their infants. It’s among numerous cases challenging Trump’s January order denying citizenship to those born to parents living in the U.S. illegally or temporarily. The plaintiffs are represented by the American Civil Liberties Union and others.
ä See BIRTHRIGHT, page 4A
101ST yEAR, NO. 11