People
Women in Chemistry Josie Gaynord
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osie Gaynord is a PhD candidate here under the supervision of Professor David Spring. Her research looks at one of the biggest problems threatening global public health: antimicrobial resistance.
My research sets out to develop new types of antibiotics. Antimicrobial resistance is a global concern at the moment which could threaten public health and food provision as bacteria can develop resistance quickly to common antibiotics. My research is looking at creating new antibiotics which combine old and new drugs with different mechanisms of actions to try and prevent resistance from developing. As a chemist, I am constantly amazed by biology. Some of my research is looking into creating new drugs for bloodrelated diseases, and recently I was able to spend the day looking at blood cells through a microscope – this might not sound very interesting but being able to see it all with my own eyes was incredible and not something you’re able to do day-to-day as a chemist. I want to improve healthcare and this helps spur me on when nothing is working. I think it’s important for all scientists to keep in mind why we want to do our research, and why it is important. I hope my research will lead to at least one drug which is more effective, or has fewer side effects, that what is currently available to patients. My work is laboratory-based – I spend the majority of my time synthesising biologically-relevant compounds. To test these, I visit groups or institutions that the Spring Group has collaborations with, including other departments, other universities and industrial pharmaceutical companies (all within Cambridge). I also have a collaborative research project with a group at the Technical University of Denmark, so have travelled there in the past. It’s always a great moment when I finally manage to make a compound that I’ve been working on for months. After trying again and again, it’s such a good feeling when the hard work pays off. I am lucky that I am surrounded by amazing, inspirational and nurturing women who are there to help me and prove that women can succeed in STEMM. Having mentors and strong female friendships within your field is very important. You should always be ambitious and work towards your goals, but remember to give back. Do every outreach, public speaking and wider-engagement event you are offered, because representation is one of the most important things. Subconsciously, young girls will never believe that they can be successful if women in STEMM are not visible. •
This story, by Sarah Collins, first appeared on the University website as part of their ‘Women in STEM’ series.
Tamsin Newlove
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amsin Newlove was 15 when she obtained her Maths A Level, and 17 when she won a Roentgenium Award (the highest award) in the Cambridge Chemistry Challenge. Along with the other winners, she was invited to a Chemistry summer school here – an experience that encouraged this Southampton state school student to apply to Cambridge for Natural Sciences. She is now a fourth-year undergraduate here, working towards her MSci.
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I have always enjoyed science. Perhaps I get that from Mum who used to be a nurse and was very good at maths and science. My sister studied science subjects too and that spurred me on, because we’re only one school year apart and quite competitive! I was given a lot of support by my school and sixth form college. Both took part in outreach events to encourage our interest in science. I remember some university students bringing a planetarium into our school, and I did a trip to the Chemistry Department at Southampton University with my sixth form college. It was a large college with a good science department, so it had the resources and advisers to support students like me who wanted to apply to Oxbridge. I’ve now been here three years and this summer I did a project with the Grey Group where they study the nature of solid-state materials that have applications in supercapacitors, fuel cells, and batteries. Before it came to applying for a job or PhD, I wanted to get some experience in a research lab to work out if it was something I’d want to do in the future. I spent eight weeks researching the solid electrolyte interphase (SEI) in symmetric Li/Li cells. The SEI acts as a barrier between the electrolyte solution and the electrode, so it plays a major role in battery performance, determining important factors such as lifespan and safety. It’s hard to analyse as it’s only a thin layer and is trapped at the interface. I was trying to characterise it by looking at ways to simulate its properties. The idea was to take a polymer, cast it with a salt, and investigate the way in which it conducts, and what happens to its conduction if you bring in other additives. It was a great learning experience as it was very different from what I did in my BA. I had never worked with polymers before – because it’s not something you do as an undergraduate – so for me that was really interesting. And previously I’d only used solution NMR spectrometry to analyse organic compounds and assign the resultant peaks. The Grey Group does a lot of work in solid state NMR, which is quite different, and they investigate other nuclei alongside carbon and proton. I experienced many other techniques that were new to me, such as using a ‘glove box’ under an argon atmosphere (when I was working with lithium) and doing impedance spectroscopy. The funding for my summer project came from a donation given by an alumnus and I am very grateful for his generosity. Cambridge is an expensive place to stay and without the funding, I wouldn’t have been able to do this project. It was a great opportunity and I feel I learned a great deal in a short space of time. It also helped me discover how much I enjoy research and made me think more about applying for a PhD. •
We are grateful to alumnus Dr Robert Perrin (King’s College, 1948) for his recent donation to support summer projects including Tamsin’s. These projects give undergraduates valuable laboratory experience, expose them to new areas of science, and help them understand how the chemistry they study is applied in practice. We have more demand from students than we can currently meet, so if you too would like to fund a project, please contact our Head of Department, Dr James Keeler: chemhod@hermes.cam.ac.uk
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Issue 60
Winter 2019