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Sustainability at AstreaBio_1pg_V2

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Sustainability at Astrea Bioseparations

Manufacturing at our Isle of Man site

Sustainability is embedded in how we design and manufacture bioseparation resins and solutions on our Isle of Man facility, with a focus on efficient resource use, responsible operations, and reliable manufacturing performance.

Sustainable, water-based manufacturing

PuraBead® resins are based on agarose derived from sustainably harvested red seaweed, a renewable biological resource. Manufacturing of the native bead uses a fully aqueous process that avoids oils and oil-derived solvents, helping reduce solvent emissions and complex waste streams.

Our atomization-based bead formation technology is designed to produce highly uniform beads with consistent morphology and narrow particle size distribution. This supports predictable chromatography performance while reducing reprocessing requirements and manufacturing waste.

Manufacturing processes are designed for scalable production, robust batch repeatability, and long operational resin lifetime to help support efficient bioprocessing operations.

Energy and resource efficiency

Manufacturing processes operate at moderate temperatures and pressures, avoiding energy-intensive solvent evaporation or distillation steps. Shared utilities, optimized scheduling, and controlled cleaning procedures help reduce energy and water demand across operations.

The predominantly aqueous nature of PuraBead® manufacture also simplifies wastewater handling compared with solventintensive manufacturing systems.

Responsible operations and supply

We take a disciplined approach to solvent handling, materials management, and waste reduction across manufacturing operations.

Packaging and logistics practices include recyclable HDPE containers, reusable pallets, and groupage or bulk shipping where feasible to help reduce packaging waste and transportation emissions.

Operations are conducted under an ISO 9001-certified Quality Management System with full traceability of raw materials, process parameters, and finished products.

Supporting sustainable bioprocessing

We work collaboratively with customers to support efficient scale-up, consistent manufacturing performance, and responsible process development.

Through carefully managed operations and continuous improvement, we aim to support efficient and responsible bioprocessing through reliable chromatography media and transparent manufacturing practices.

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