Genetics and Genomics Nationwide Children's at the Forefront - Everything Matters in Patient Care

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Where Passion Meets Purpose

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s part of the 2017-2022 Strategic Plan, Nationwide Children's Hospital committed to Best Outcomes for all children. This commitment includes developing cures for rare diseases and a better understanding of the treatment of genetic conditions in children. Genomics is one of the areas of focus

Lee Ann Wallace that we believe will accelerate our MBA, BSN, RN, NEA-BC Journey to Best Outcomes. At the Abigail Senior Vice President, Patient Care Services, Chief Nursing Officer

Wexner Research Institute at Nationwide Children’s Hospital, our world-renowned research teams are breaking new ground in genomics, gene therapy, and tissue engineering. This research will provide transformational work in understanding the genetic causes of disease, an ability to more rapidly sequence genomes, as well as reducing the cost of this state-ofthe-art medical science and technology. Rather than a one size fits all approach, individualized treatment care plans can be developed using high precision diagnostics. Large research studies are taking place on the identification of cancer tumor DNA while understanding what processes cause a normal cell to

become a cancer cell. Developing a better understanding of the cancer location and causes of these over-expressed genes, we will increase our successful outcomes for cancer therapies. The ability to translate their research into treatment using whole-exome sequencing allowing for diagnosis of pediatric conditions that traditional tests and investigation would not be able to identify. Through genome sequencing, targeted therapies, and medications based on the identification of genetic errors will be developed, all leading to improved outcomes.

The Steve and Cindy Rasmussen Institute for Genomic Medicine: An Overview Richard K. Wilson, PhD, Executive Director, The Steve and Cindy Rasmussen Institute for Genomic Medicine, The Abigail Wexner Research Institute at Nationwide Children’s Hospital Elaine R. Mardis, PhD, Co-executive Director, The Steve and Cindy Rasmussen Institute for Genomic Medicine, The Abigail Wexner Research Institute at Nationwide Children’s Hospital

While work has been focused on rare genetic conditions and cancer, the future is wide open. Other areas of future expansion include diagnosis and treatment of seizure disorders and the ability for rapid identification of neonatal conditions. As care team providers, we need to continue to expand our knowledge and understanding of genomics in our own areas of practice, while identifying the impact of these discoveries on our patients and their families.

2017-2022

JOURNEY TO BEST OUTCOMES VISION

BEST OUTCOMES

GOAL Pre-eminent Clinical & Research Programs

One Team Values

for Kids Everywhere

CORE STRATEGIES Operational Excellence

Growth & Partnerships Education

4 | IN PATIENT CARE

ACCELERATORS Quality, Safety & Service

Behavioral Health

Genomics

Wellness/ Population Health

IN PATIENT CARE | 5


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Genetics and Genomics Nationwide Children's at the Forefront - Everything Matters in Patient Care by NCHFoundation - Issuu